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Santa Fe Vacation Packages

Build your package with 2 more options

Santa Fe Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Museo Relic

Hotel Museo Relic

2 out of 5
Price was $835, price is now $577 per person
$577
per person
Oct 20 - Oct 24
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Stay at this hostel in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Totalmente diferente a como se ve en las fotos y mal trato por parte de la recepcionista

Reviewed on Sep 5, 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Save 100% on your flight
Price was $2,063, price is now $963 per person
$963
per person
Oct 24 - Oct 30
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Save 100% on your flight
Price was $1,913, price is now $981 per person
$981
per person
Nov 27 - Dec 1
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
A little over priced water but everyt

Reviewed on Sep 11, 2026

Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Price was $1,366, price is now $910 per person
$910
per person
Oct 24 - Oct 30
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
The SPA do not work. The Jaccuzi do not work

Reviewed on Sep 11, 2026

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was $1,234, price is now $823 per person
$823
per person
Nov 20 - Nov 25
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.

Yoo by Wynwood House

Yoo by Wynwood House

4 out of 5
Price was $1,519, price is now $1,089 per person
$1,089
per person
Nov 3 - Nov 8
found 1 day ago
Roundtrip flight included
San Juan (SJU) to Panama City (PTY)
Stay at this condo in Panama City. Enjoy free WiFi, a fitness center, and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Unfortunately the name of the property was not Yoo by Wynwood. It is P. H. Yoo Panama & Arts Tower. This detail that was incorrect cost us time, money and stress at the beginning of our trip. We weren't able to get in touch with anyone at the property or at expedia and we ended up having to cross reference google photos to figure out the correct name and address of the location. This took us about an hour to do in a Country that we had never been to. We are very displeased with Expedia about this. We still have not been contacted by anyone.

Reviewed on Jul 26, 2025

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Price was $1,390, price is now $1,020 per person
$1,020
per person
Oct 24 - Oct 30
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Thanks

Reviewed on Sep 8, 2026

Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House

3.5 out of 5
Price was $1,490, price is now $1,114 per person
$1,114
per person
Nov 27 - Dec 1
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, cable TV channels, and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Santa Fe Vacation Packages 3-4 Night Stays

Price found within the past 48 hours. Click for updated prices.
La Moderna Downtown Nights by Wynwood

La Moderna Downtown Nights by Wynwood

3 out of 5
Casco Viejo
Price was $1,031, price is now $687 per person
$687
per person
Oct 20 - Oct 24
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,913, price is now $981 per person
$981
per person
Nov 27 - Dec 1
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was $1,292, price is now $817 per person
$817
per person
Nov 27 - Dec 1
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Donovan Night Scene by Wynwood

Donovan Night Scene by Wynwood

3 out of 5
Casco Viejo
Price was $1,051, price is now $698 per person
$698
per person
Oct 20 - Oct 24
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)

Santa Fe Vacation Packages 5-7 Night Stays

Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was $1,234, price is now $823 per person
$823
per person
Nov 20 - Nov 25
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Save 100% on your flight
Price was $2,063, price is now $963 per person
$963
per person
Oct 24 - Oct 30
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $2,196, price is now $1,050 per person
$1,050
per person
Nov 20 - Nov 25
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
San Francisco
Price was $1,366, price is now $910 per person
$910
per person
Oct 24 - Oct 30
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Copa
Sat, Oct 17 - Tue, Oct 27
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$257 Roundtrip, just found
$257
Roundtrip
just found
Select Copa flight, departing Sat, Oct 17 from Juan Santamaría Intl. to Tocumen Intl., returning Tue, Oct 27, priced at $257 just found
Copa
Sat, Oct 31 - Mon, Nov 9
MIA
Miami Intl.
PTY
Tocumen Intl.
$502 Roundtrip, found 4 hours ago
$502
Roundtrip
found 4 hours ago
Select Copa flight, departing Sat, Oct 31 from Miami Intl. to Tocumen Intl., returning Mon, Nov 9, priced at $502 found 4 hours ago
Copa
Mon, Oct 12 - Tue, Oct 27
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$514 Roundtrip, found 1 day ago
$514
Roundtrip
found 1 day ago
Select Copa flight, departing Mon, Oct 12 from Hartsfield-Jackson Atlanta Intl. to Tocumen Intl., returning Tue, Oct 27, priced at $514 found 1 day ago
Copa
Sun, Nov 8 - Thu, Nov 12
LAX
Los Angeles Intl.
PTY
Tocumen Intl.
$534 Roundtrip, found 2 hours ago
$534
Roundtrip
found 2 hours ago
Select Copa flight, departing Sun, Nov 8 from Los Angeles Intl. to Tocumen Intl., returning Thu, Nov 12, priced at $534 found 2 hours ago