Search Deals onPreston Vacation Packages
Preston Flight + Hotel Packages
Price found within the past 48 hours. Click for updated prices.
MainStay Suites Rochester South Mayo Clinic
Price was $532, price is now $527 per person
$527
per person
Dec 4 - Dec 7
found 1 day ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Rochester (RST)
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Mayo Civic Center and Marcus Rochester Cinema are located nearby.
The room was large and well lit, the bed was comfortable, and the temperature controls worked well.
Reviewed on Nov 2, 2026
The Berkman
Price was $1,011, price is now $910 per person
$910
per person
Dec 7 - Dec 11
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Rochester (RST)
Book a stay at this golf aparthotel in Rochester. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular attractions Mayo Civic Center and Kutzky Park Tennis Center are located nearby.
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Price was $886, price is now $809 per person
$809
per person
Dec 7 - Dec 11
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Rochester (RST)
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff in our reviews. Popular attractions Mayo Civic Center and Kutzky Park Tennis Center are located nearby.
Alexander Mansion Bed and Breakfast
Price was $627, price is now $577 per person
$577
per person
Dec 4 - Dec 7
found 1 day ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Rochester (RST)
Stay at this B&B in Winona. Enjoy free parking, a business center, and daily housekeeping. Popular attractions Winona Arts Center and Watkins Heritage Museum are located nearby.
Wonderful host Richard and the beautiful home
Reviewed on Nov 2, 2026
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Price was $811, price is now $752 per person
$752
per person
Dec 7 - Dec 11
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Rochester (RST)
Book a stay at this golf hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. Popular attractions Mayo Civic Center and Soldiers Field Veterans Memorial are located nearby.
Holiday Inn Express Rochester South - Mayo Area by IHG
Price was $790, price is now $742 per person
$742
per person
Dec 7 - Dec 11
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Rochester (RST)
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Mayo Civic Center and Marcus Rochester Cinema are located nearby.
The first room we were given did not have a working AC unit nor a working landline phone to call the desk. (Walking down to talk to the gal at the desk was easy, I just found it humorous that I couldn’t call her from the room. The second room we were given was awesome! And breakfast was great (pancake machine, omelets, biscuits and gravy, etc) I would stay here again if we are in the area.
Reviewed on Nov 3, 2026
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Price was $810, price is now $763 per person
$763
per person
Dec 7 - Dec 11
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Rochester (RST)
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free parking, and a free area shuttle. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Mayo Civic Center and Kutzky Park Tennis Center are located nearby.
Very clean nice spread for breakfast
Reviewed on Oct 28, 2026
Quality Inn near Medical Center
Price was $546, price is now $540 per person
$540
per person
Dec 4 - Dec 7
found 1 day ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Rochester (RST)
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Mayo Civic Center and Northern Hills Golf Course are located nearby.
Always a good experience. I highly recommend them
Reviewed on Nov 3, 2026
Preston Vacation Packages 3-4 Night Stays
Price found within the past 48 hours. Click for updated prices.
Preston Vacation Packages 5-7 Night Stays
Price found within the past 48 hours. Click for updated prices.
Top Flight Deals
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
Thu, Nov 12 - Mon, Nov 23
DTW
Detroit Metropolitan Wayne County
RST
Rochester Intl.
$388 Roundtrip, found 1 hour ago
$388
Roundtrip
found 1 hour ago
Sat, Nov 7 - Tue, Nov 10
EWR
Newark Liberty Intl. Airport
RST
Rochester Intl.
$402 Roundtrip, found 2 hours ago
$402
Roundtrip
found 2 hours ago
Sat, Nov 7 - Mon, Nov 9
JFK
John F. Kennedy Intl.
RST
Rochester Intl.
$541 Roundtrip, found 1 hour ago
$541
Roundtrip
found 1 hour ago
Sat, Nov 7 - Sat, Nov 7
LGA
LaGuardia
RST
Rochester Intl.
$931 Roundtrip, found 1 hour ago
$931
Roundtrip
found 1 hour ago
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