Search Deals onRío Sereno Vacation Packages
Río Sereno Flight + Hotel Packages
Price found within the past 48 hours. Click for updated prices.
Decapolis Hotel Panama City
Price was $1,352, price is now $903 per person
$903
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Decapolis hotel is in an excellent location, the breakfast buffet, the Bistro restaurant restaurant and gym are all nice. The rooms are clean and the bedding comfortable staff were friendly and helpful. However, the carpets especially on floor 19 need replacing or a deep clean. Floor 19 is also pretty loud I'm not sure what the cause is but I suspect it's the air-conditioning.
Reviewed on Sep 9, 2026
Central Hotel Panama Casco Viejo
Save 100% on your flight
Price was $2,732, price is now $1,233 per person
$1,233
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Very very nice, especially given that this hotel is a historic building. The food is excellent in the restaurants too. The breakfast is yummy!
Reviewed on Sep 9, 2026
Megapolis Hotel Panamá
Save 100% on your flight
Price was $1,736, price is now $963 per person
$963
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Riande Aeropuerto Hotel & Casino
Price was $1,487, price is now $960 per person
$960
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.
Casa Mallet by Wynwood House
Save 100% on your flight
Price was $2,956, price is now $2,000 per person
$2,000
per person
Oct 31 - Nov 7
found 1 day ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, parking (surcharge), and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Nice apartment ! Clean and great location
Reviewed on Aug 13, 2026
Hotel Riu Plaza Panama
Price was $1,429, price is now $979 per person
$979
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
The property was amazing. I enjoyed my stay.
Beautiful pool. The breakfast buffet was huge, and all the food was delicious.
Hotel also had a fine dining restaurant, bar with great food and a grab and go shop with hot food and pastry.
Staff was helpful.
Reviewed on Sep 9, 2026
Las Americas Golden Tower Panama
Price was $1,497, price is now $1,040 per person
$1,040
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Thanks
Reviewed on Sep 8, 2026
Hyatt Regency Panama City
Price was $1,533, price is now $1,089 per person
$1,089
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and 2 restaurants. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Río Sereno Vacation Packages 3-4 Night Stays
Price found within the past 48 hours. Click for updated prices.
Río Sereno Vacation Packages 5-7 Night Stays
Price found within the past 48 hours. Click for updated prices.
Top Flight Deals
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
Sat, Sep 12 - Mon, Sep 21
FLL
Fort Lauderdale - Hollywood Intl.
DAV
Enrique Malek Intl.
$630 Roundtrip, found 9 hours ago
$630
Roundtrip
found 9 hours ago
Tue, Sep 15 - Thu, Sep 17
MIA
Miami Intl.
DAV
Enrique Malek Intl.
$680 Roundtrip, found 9 hours ago
$680
Roundtrip
found 9 hours ago
Fri, Sep 11 - Fri, Sep 18
FLL
Fort Lauderdale - Hollywood Intl.
DAV
Enrique Malek Intl.
$1,018 Roundtrip, found 2 hours ago
$1,018
Roundtrip
found 2 hours ago
Sat, Sep 12 - Thu, Oct 1
JFK
John F. Kennedy Intl.
DAV
Enrique Malek Intl.
$1,120 Roundtrip, found 9 hours ago
$1,120
Roundtrip
found 9 hours ago
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