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Santa Catalina Vacation Packages

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A tropical island with a sandy beach and turquoise waters.

Santa Catalina
Hicaco
Veraguas
Panama
Mexico and Central America
Hotwire.com

Santa Catalina Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Hotel Riu Plaza Panama

5 out of 5

Price was $1,025, price is now $761 per person

$761

per person

Oct 15 - Oct 18

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.

The hotel was clean, staff was very courteous and breakfast was excellent 👌 I definitely recommend. You will have a great experience.

Reviewed on Jul 20, 2026

Central Hotel Panama Casco Viejo

4 out of 5

Save 100% on your flight

Price was $1,747, price is now $928 per person

$928

per person

Sep 3 - Sep 7

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

The breakfast was so good! Best fresh squeezed orange and pineapple juice.

Reviewed on Jul 20, 2026

Megapolis Hotel Panamá

4.5 out of 5

Price was $1,483, price is now $920 per person

$920

per person

Sep 3 - Sep 7

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

I highly recommend this hotel….. from the buffet breakfast straight to the cleanliness 9.5/10

Reviewed on Jul 19, 2026

Riande Aeropuerto Hotel & Casino

4 out of 5

Price was $1,146, price is now $819 per person

$819

per person

Sep 3 - Sep 7

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.

Las Clementinas

3.5 out of 5

Price was $1,363, price is now $1,024 per person

$1,024

per person

Sep 20 - Sep 25

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Stay at this aparthotel in Panama City. Enjoy free WiFi, parking (surcharge), and an airport shuttle (surcharge). Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Great food and location

Reviewed on Jul 11, 2026

Decapolis Hotel Panama City

4 out of 5

Price was $1,045, price is now $794 per person

$794

per person

Sep 10 - Sep 14

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Las Americas Golden Tower Panama

4 out of 5

Price was $985, price is now $763 per person

$763

per person

Oct 15 - Oct 18

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Clean room

Reviewed on Jul 14, 2026

Hyatt Regency Panama City

5 out of 5

Price was $1,153, price is now $908 per person

$908

per person

Sep 3 - Sep 7

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and 2 restaurants. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.