Search for Cheap Deals on
Spa Resort Hotels in Santiago

Check Last Minute Santiago Hotel Deals

Tonight Nov 23 - Nov 24Next weekend Nov 29 - Dec 1

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking, and you save up to 60%!


Featured Santiago Resorts & Hotels with Spas

Hotel Gran David
Hotel Gran David
3.5 out of 5
Vía Interamericana, Santiago, Veraguas
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Hotel Gran David
Hotel Mykonos Panama
Hotel Mykonos Panama
3.5 out of 5
Panamerican Highway, in front of Ruben Cantu Airport, Nuevo Santiago, Veraguas
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star spa hotel in Nuevo Santiago. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Parque Nacional Cerro Hoya and Cerámica ...
Hotel Mykonos Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.