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Santiago Vacation Packages

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Santiago Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
per person
Jun 20 - Jun 23
found 14 hours ago
Roundtrip flight included
Medellín (MDE) to Panama City (PTY)
Stay at this 3-star golf B&B in Rio Hato. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Playa Blanca and Farallón Beach are located nearby.
Residencia Natural

Residencia Natural

3 out of 5
per person
Jul 16 - Jul 21
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this 3-star beach aparthotel in Bastimentos. Enjoy free WiFi, free parking, and a beach locale. Popular attractions Playa Larga and Nivida Bat Cave are located nearby.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Save 100% on your flight
per person
Jul 16 - Jul 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
The Gray by Wynwood House

The Gray by Wynwood House

2 out of 5
Save 100% on your flight
per person
Jul 16 - Jul 23
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Punta Caracol Acqua Lodge

Punta Caracol Acqua Lodge

3.5 out of 5
Save 100% on your flight
per person
Jul 16 - Jul 21
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this 3.5-star beach lodge in Bocas del Toro. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions La Gruta Cave and Institute for Tropical Ecology & Conservation - Bocas del Toro Biological Station are located nearby.
La Coralina Island House

La Coralina Island House

3.5 out of 5
per person
Jul 16 - Jul 21
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this 3.5-star beach hotel in Bocas del Toro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Paunch Beach and Tortuga Beach are located nearby.
NAYARA Bocas del Toro

NAYARA Bocas del Toro

4 out of 5
Save 100% on your flight
per person
Jul 16 - Jul 21
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this 4-star spa hotel in Isla Frangipani. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our reviews.

Santiago Vacation Packages 3-4 Night Stays

Price found within the past 48 hours. Click for updated prices.
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
per person
Jun 20 - Jun 23
found 14 hours ago
Roundtrip flight included
Medellín (MDE) to Panama City (PTY)
Residencia Natural

Residencia Natural

3 out of 5
Save 100% on your flight
per person
Jun 20 - Jun 23
found 15 hours ago
Roundtrip flight included
Medellín (MDE) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
per person
Jul 16 - Jul 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Punta Caracol Acqua Lodge

Punta Caracol Acqua Lodge

3.5 out of 5
Punta Caracol
per person
Jul 9 - Jul 13
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

Santiago Vacation Packages 5-7 Night Stays

Price found within the past 48 hours. Click for updated prices.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
per person
Jul 2 - Jul 7
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Residencia Natural

Residencia Natural

3 out of 5
per person
Jul 16 - Jul 21
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
The Gray by Wynwood House

The Gray by Wynwood House

2 out of 5
Bella Vista
Save 100% on your flight
per person
Jul 16 - Jul 23
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Punta Caracol Acqua Lodge

Punta Caracol Acqua Lodge

3.5 out of 5
Punta Caracol
Save 100% on your flight
per person
Jul 16 - Jul 21
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Copa
Wed, May 21 - Sun, May 25
MIA
Miami Intl.
PTY
Tocumen Intl.
$266 Roundtrip, found 22 hours ago
$266
Roundtrip
found 22 hours ago
Select Copa flight, departing Wed, May 21 from Miami Intl. to Tocumen Intl., returning Sun, May 25, priced at $266 found 22 hours ago
Copa
Mon, Aug 11 - Mon, Aug 18
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$314 Roundtrip, found 6 days ago
$314
Roundtrip
found 6 days ago
Select Copa flight, departing Mon, Aug 11 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Mon, Aug 18, priced at $314 found 6 days ago
Aeromexico
Sat, Jul 19 - Sat, Jul 26
MEX
Mexico City Intl.
PTY
Tocumen Intl.
$352 Roundtrip, found 6 days ago
$352
Roundtrip
found 6 days ago
Select Aeromexico flight, departing Sat, Jul 19 from Mexico City Intl. to Tocumen Intl., returning Sat, Jul 26, priced at $352 found 6 days ago
Delta
Fri, Jun 13 - Sat, Jun 14
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$397 Roundtrip, found 20 hours ago
$397
Roundtrip
found 20 hours ago
Select Delta flight, departing Fri, Jun 13 from Hartsfield-Jackson Atlanta Intl. to Tocumen Intl., returning Sat, Jun 14, priced at $397 found 20 hours ago