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Santo Domingo Vacation Packages

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Santo Domingo
Los Santos
Panama
Mexico and Central America
Hotwire.com

Santo Domingo Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Mahogany Suites

2 out of 5

Price was $978, price is now $471 per person

$471

per person

Apr 5 - Apr 9

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this golf hotel in Arraijan. Enjoy free WiFi, a golf course, and an outdoor pool. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.

Hotel Riu Plaza Panama

5 out of 5

Price was $1,142, price is now $803 per person

$803

per person

Mar 1 - Mar 6

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Central Hotel Panama Casco Viejo

4 out of 5

Price was $1,690, price is now $1,268 per person

$1,268

per person

Mar 20 - Mar 23

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Nomada Republic Hotel El Valle

3 out of 5

Price was $767, price is now $582 per person

$582

per person

Apr 15 - Apr 19

found 18 hours ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Stay at this hotel in El Valle de Anton. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Chorro Macho Waterfall and El Chorro Macho are located nearby.

The Gray by Wynwood House

3 out of 5

Price was $1,399, price is now $1,082 per person

$1,082

per person

Apr 3 - Apr 10

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

Stay at this apartment in Panama City. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Villa Botero By Casa Mojito B&B

3 out of 5

Price was $976, price is now $760 per person

$760

per person

Apr 9 - Apr 12

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

Book a stay at this golf B&B in Rio Hato. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Playa Blanca and Farallón Beach are located nearby.

Casa Fofo Family House

3 out of 5

Price was $1,307, price is now $1,029 per person

$1,029

per person

Apr 9 - Apr 12

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

Stay at this guesthouse in San Carlos. Enjoy free WiFi, free parking, and private pools. Popular attractions Playa La Ensenada and Playa El Palmar are located nearby.

Hilton Panama

5 out of 5

Price was $1,647, price is now $1,308 per person

$1,308

per person

Apr 3 - Apr 11

found 10 hours ago

Roundtrip flight included

Boston (BOS) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy a full-service spa, 4 restaurants, and an attached winery. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.