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Hotels in Wapello

Choose from 81 Wapello Hotel Deals

The Catfish Bend Inn & Spa

The Catfish Bend Inn & Spa

3.5 out of 5
3001 Winegard Dr, Burlington, IA
  • 4 hours drive from Mississippi River
Stay at this 3.5-star spa hotel in Burlington. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular ...
The Catfish Bend Inn & Spa
AmericInn by Wyndham West Burlington

AmericInn by Wyndham West Burlington

2.5 out of 5
628 S Gear Ave, West Burlington, IA
  • 4 hours drive from Mississippi River
Book a stay at this family-friendly hotel in West Burlington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
AmericInn by Wyndham West Burlington
Fun City Resort Hotel

Fun City Resort Hotel

3.5 out of 5
3001 Winegard Drive, Burlington, IA
  • 4 hours drive from Mississippi River
Stay at this 3.5-star family-friendly hotel in Burlington. Enjoy free WiFi, free parking, and a casino. Popular attractions FunCity and Catfish Bend Casino are ...
Fun City Resort Hotel
Best Western Mt. Pleasant Inn

Best Western Mt. Pleasant Inn

2.5 out of 5
810 N Grand Avenue, Mount Pleasant, IA
  • 4 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Mount Pleasant. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Best Western Mt. Pleasant Inn
Best Western Muscatine / Pearl City Hotel

Best Western Muscatine / Pearl City Hotel

2.5 out of 5
305 Cleveland St, Muscatine, IA
  • 5 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Muscatine. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
Best Western Muscatine / Pearl City Hotel
AmericInn by Wyndham Muscatine

AmericInn by Wyndham Muscatine

2.5 out of 5
3115 Hwy 61 North, Muscatine, IA
  • 5 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and ...
AmericInn by Wyndham Muscatine
Super 8 by Wyndham Burlington

Super 8 by Wyndham Burlington

2 out of 5
3001 Kirkwood St, Burlington, IA
  • 4 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Burlington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Super 8 by Wyndham Burlington
Holiday Inn Express Hotel & Suites Burlington by IHG

Holiday Inn Express Hotel & Suites Burlington by IHG

2.5 out of 5
1605 North Roosevelt Ave, Burlington, IA
  • 4 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Burlington. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Catfish Bend Casino and FunCity ...
Holiday Inn Express Hotel & Suites Burlington by IHG
AmericInn by Wyndham Mount Pleasant

AmericInn by Wyndham Mount Pleasant

2 out of 5
1100 N Grand Ave, Mount Pleasant, IA
  • 4 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Mount Pleasant. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
AmericInn by Wyndham Mount Pleasant
Quality Inn Burlington near Hwy 34

Quality Inn Burlington near Hwy 34

2.5 out of 5
3051 Kirkwood St, Burlington, IA
  • 4 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Burlington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Quality Inn Burlington near Hwy 34
Hampton Inn Muscatine

Hampton Inn Muscatine

2.5 out of 5
3303 N Port Drive, Muscatine, IA
  • 5 hours drive from Mississippi River
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and Muscatine Municipal Golf ...
Hampton Inn Muscatine
Comfort Inn Muscatine near Hwy 61

Comfort Inn Muscatine near Hwy 61

2.5 out of 5
115 Cleveland St, Muscatine, IA
  • 5 hours drive from Mississippi River
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and Geneva Golf and Country ...
Comfort Inn Muscatine near Hwy 61
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Wapello

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Wapello.

Choosing the right hotel in Iowa has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Wapello’s 81 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $62. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Wapello hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Wapello. No matter your reason for visiting Wapello, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Wapello hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Wapello for as low as $62.

How many hotels are there in Wapello?

With over 81 hotels in Wapello, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $62.

How to find cheap car rentals in Wapello?

Finding a cheap car rental deal in Wapello is as easy as scoring cheap hotels in Wapello. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.