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4 Star Hotels in Syracuse

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Featured 4 Star Syracuse Hotels

Grand Hotel Villa Politi
4 out of 5
Fully refundableReserve now, pay when you stay
  • 16 min walk from Lungomare di Ortigia
The price is $124 per night from Jan 7 to Jan 8
$124
includes taxes & fees
Jan 7 - Jan 8, 2025
Stay at this 4-star beach hotel in Syracuse. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the comfy rooms in our ...
Grand Hotel Villa Politi
Algila' Ortigia Charme Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min walk from Lungomare di Ortigia
The price is $233 per night from Jan 3 to Jan 4
$233
includes taxes & fees
Jan 3 - Jan 4, 2025
Stay at this 4-star family-friendly hotel in Syracuse. Enjoy free breakfast, free WiFi, and 2 bars/lounges. Our guests praise the breakfast and the helpful staff ...
Algila' Ortigia Charme Hotel
Mercure Siracusa Prometeo
4 out of 5
  • 19 min walk from Lungomare di Ortigia
Stay at this 4-star spa hotel in Syracuse. Enjoy free WiFi, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular ...
Mercure Siracusa Prometeo
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Palazzo Artemide - VRetreats
4 out of 5
Fully refundableReserve now, pay when you stay
  • 9 min walk from Lungomare di Ortigia
The price is $157 per night from Jan 7 to Jan 8
$157
includes taxes & fees
Jan 7 - Jan 8, 2025
Stay at this 4-star hotel in Syracuse. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular ...
Palazzo Artemide - VRetreats
Hotel Palazzo Cavalieri
4 out of 5
Fully refundableReserve now, pay when you stay
  • 7 min walk from Lungomare di Ortigia
The price is $93 per night from Jan 3 to Jan 4
$93
includes taxes & fees
Jan 3 - Jan 4, 2025
Stay at this 4-star hotel in Syracuse. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Santa Lucia Bridge and Syracuse ...
Hotel Palazzo Cavalieri
Eureka Palace Hotel Spa Resort
4 out of 5
Fully refundableReserve now, pay when you stay
  • 18 min drive from Lungomare di Ortigia
The price is $108 per night from Jan 1 to Jan 2
$108
includes taxes & fees
Jan 1 - Jan 2, 2025
Stay at this 4-star spa hotel in Syracuse. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
Eureka Palace Hotel Spa Resort
Grande Albergo Alfeo
4 out of 5
Fully refundableReserve now, pay when you stay
  • 7 min walk from Lungomare di Ortigia
The price is $135 per night from Jan 6 to Jan 7
$135
includes taxes & fees
Jan 6 - Jan 7, 2025
Stay at this 4-star business-friendly hotel in Syracuse. Enjoy free breakfast, free WiFi, and room service. Popular attractions Syracuse Forum Ruins and Santa ...
Grande Albergo Alfeo
UNAHOTELS One Siracusa
4 out of 5
Fully refundableReserve now, pay when you stay
  • 23 min walk from Lungomare di Ortigia
The price is $162 per night from Jan 6 to Jan 7
$162
includes taxes & fees
Jan 6 - Jan 7, 2025
Stay at this 4-star spa hotel in Syracuse. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
UNAHOTELS One Siracusa
Charme Hotel Henry's House
4 out of 5
  • 14 min walk from Lungomare di Ortigia
The price is $242 per night from Jan 2 to Jan 3
$242
includes taxes & fees
Jan 2 - Jan 3, 2025
Stay at this 4-star boutique hotel in Syracuse. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular ...
Charme Hotel Henry's House
Hotel Panorama
4 out of 5
Fully refundableReserve now, pay when you stay
  • 29 min walk from Lungomare di Ortigia
The price is $87 per night from Jan 2 to Jan 3
$87
includes taxes & fees
Jan 2 - Jan 3, 2025
Stay at this 4-star business-friendly hotel in Syracuse. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Rope-makers' Cave and ...
Hotel Panorama
Hotel Livingston Siracusa
4 out of 5
  • 10 min walk from Lungomare di Ortigia
Stay at this 4-star hotel in Syracuse. Enjoy free breakfast, free WiFi, and private spa tubs. Our guests praise the helpful staff in our reviews. Popular attractions ...
Hotel Livingston Siracusa
Hotel Parco delle Fontane
4 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min drive from Lungomare di Ortigia
The price is $121 per night from Jan 26 to Jan 27
$121
includes taxes & fees
Jan 26 - Jan 27, 2025
Stay at this 4-star property in Syracuse. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Rope-makers' Cave and Latomia del Paradiso are ...
Hotel Parco delle Fontane
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4-star hotels in Syracuse

When you want to live it up, but not bust your bank account, then there’s nothing better than a 4-star hotel in Syracuse for your next trip. You’ll get all the amenities you can think of (and then some) at a rate within your means.

No fault in our stars

So what’s with the star rating anyway? Good question. The star rating has little to do with the price, and more to do with the amenities. 4-Star hotels in Syracuse as well as everywhere else, usually have all those thoughtful touches that make you go “Ooh,” “Ahh,” and ”YES!” Think amenities like luxury bedding, high-end electronics, concierge service, and restaurants that make eating in a gourmet experience.

Stars that shine

You know there are as many underground spots, inviting lounges, memory-making music venues as there are stars in the sky. But you’ll need the funds to check them all off. That’s why we give you the chance to take us up on the Hotwire Hot Rate. You can snag Syracuse 4-star hotels and still have plenty of leftover cash to paint the town whatever color you want. Filter hotels by:

  • Hotwire Hot Rate: We’ll snag you a crazy deal on a room by finding your hotel name after you book.
  • Price: You know that paying full price is for suckers? You can get a cheap 4-star hotel in Syracuse starting at $87 per night.
  • Amenities: What makes you flip for your trip? Full-service spa? Heated pool? 24-hour room service? Get a hotel that’ll send you over the moon.

Do you deserve a swanky hotel with a ton of amenities? Yes, yes you do. And you also deserve a sweet deal on it. Book with Hotwire today and get that star-studded Syracuse 4-star hotel and have plenty of cash left over to spend at that secret super star joint in the city.