Search Cheap Flights to
Mission

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Cheap Flights to Mission

Fall in love at first flight with your vacation to Mission by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Mission on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Mission, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Mission

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Mission with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MFE airport.

What is the cheapest month to fly to Mission?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Mission are in , but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Mission?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find  to choose from for your flight to Mission.

What airport is best to fly into Mission?

When you’re planning your trip to Mission, convenience is the name of the game. Luckily, Mission Miller Intl. Airport is nearby so you can deplane and get going on checking off everything on your Mission must-do list.

How much are flights to Mission?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Mission on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as , you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Mission?

The trick to saving a stack of cash on your flight to Mission? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as  right now, why wait?

Mission Flight Information
Destination airport
Mission
Destination airport IATA code
MFE

Last Minute Hotel Deals in Mission

La Quinta Inn & Suites by Wyndham Mission at West McAllen

La Quinta Inn & Suites by Wyndham Mission at West McAllen

3 out of 5
805 Travis Street Mission TX
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,007 reviews)
"In the many years I’ve stayed there this night was the worse no TV in room and room started leaking when rain came. They did offer to move room for the water issue."

Reviewed on May 16, 2026

La Quinta Inn & Suites by Wyndham Mission at West McAllen
The Bungalows on Shary, Mission-McAllen

The Bungalows on Shary, Mission-McAllen

2.5 out of 5
3700 Plantation Grove Blvd Mission TX
Stay at this hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions La ...
The Bungalows on Shary, Mission-McAllen
Motel 6 Mission, TX

Motel 6 Mission, TX

2 out of 5
1813 E Expressway 83 Mission TX
Stay at this motel in Mission. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.6/10 Excellent! (1,183 reviews)
"Check in person was nice, rooms were clean."

Reviewed on May 17, 2026

Motel 6 Mission, TX
Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG

Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG

2.5 out of 5
901 S Shary Rd Mission TX
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Popular attractions La Plaza Mall and Cinemark Tinseltown ...
8.8/10 Excellent! (1,019 reviews)
"We had an amazing stay at this hotel! Everything was clean, comfortable, and well-maintained. One of our favorite things was how cold the room got—we love sleeping in a nice, chilly room, and the air conditioning worked perfectly. The staff was friendly and welcoming, and the overall experience exceeded ..."

Reviewed on May 14, 2026

Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG
avid Hotel Mission East Mcallen Area by IHG

avid Hotel Mission East Mcallen Area by IHG

2 out of 5
101 Grapefruit Blvd Mission TX
Stay at this hotel in Mission. Enjoy free breakfast and a 24-hour front desk. Popular attractions La Plaza Mall and Cinemark Tinseltown USA Mission are located ...
8.6/10 Excellent! (47 reviews)
"It was amazing"

Reviewed on May 16, 2026

avid Hotel Mission East Mcallen Area by IHG
SureStay Hotel By Best Western Mission

SureStay Hotel By Best Western Mission

2.5 out of 5
609 East Interstate Highway 2 Mission TX
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free parking, and a fitness center. Popular attractions La Plaza Mall and Mission ...
SureStay Hotel By Best Western Mission
Hampton Inn & Suites Mission

Hampton Inn & Suites Mission

3 out of 5
2505 Victoria Rd Mission TX
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,003 reviews)
"Great overnight stay"

Reviewed on May 14, 2026

Hampton Inn & Suites Mission
Candlewood Suites Mission East Mcallen Area by IHG

Candlewood Suites Mission East Mcallen Area by IHG

2.5 out of 5
101 Grapefruit Blvd.Suite B. Mission TX
Stay at this hotel in Mission. Enjoy a 24-hour front desk. Popular attractions La Plaza Mall and Cinemark Tinseltown USA Mission are located nearby.
8.6/10 Excellent! (17 reviews)
"The rooms were a great size with a small kitchenette and small refrigerator. The hotel was immaculate, the beds were very comfortable, and the water pressure was great with plenty of hotel water. The hotel is a little pricey since it is right next to the Mission Event Center but the location was ..."

Reviewed on May 8, 2026

Candlewood Suites Mission East Mcallen Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Comfort Inn Near Medical Center

Comfort Inn Near Medical Center

2.5 out of 5
203 S Shary Rd Mission TX
Book a stay at this business-friendly hotel in Mission. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions La Plaza Mall and Cinemark Tinseltown ...
Comfort Inn Near Medical Center
Hampton Inn & Suites Mission

Hampton Inn & Suites Mission

3 out of 5
2505 Victoria Rd Mission TX
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,003 reviews)
"Great overnight stay"

Reviewed on May 14, 2026

Hampton Inn & Suites Mission
Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG

Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG

2.5 out of 5
901 S Shary Rd Mission TX
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Popular attractions La Plaza Mall and Cinemark Tinseltown ...
8.8/10 Excellent! (1,019 reviews)
"We had an amazing stay at this hotel! Everything was clean, comfortable, and well-maintained. One of our favorite things was how cold the room got—we love sleeping in a nice, chilly room, and the air conditioning worked perfectly. The staff was friendly and welcoming, and the overall experience exceeded ..."

Reviewed on May 14, 2026

Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG
La Quinta Inn & Suites by Wyndham Mission at West McAllen

La Quinta Inn & Suites by Wyndham Mission at West McAllen

3 out of 5
805 Travis Street Mission TX
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,007 reviews)
"In the many years I’ve stayed there this night was the worse no TV in room and room started leaking when rain came. They did offer to move room for the water issue."

Reviewed on May 16, 2026

La Quinta Inn & Suites by Wyndham Mission at West McAllen
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.