Search Cheap Flights to
Mission

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Mission Flights as Low as $222

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Delta
Delta
Delta
Delta
Delta
Delta
Delta
Delta
Delta
Delta
United
American Airlines
Delta
Delta
Bargain Flight

Cheap Flights to Mission

Fall in love at first flight with your vacation to Mission by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Mission on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Mission, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Mission

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Mission with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MFE airport.

What is the cheapest month to fly to Mission?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Mission are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Mission?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to Mission.

What airport is best to fly into Mission?

When you’re planning your trip to Mission, convenience is the name of the game. Luckily, Mission Miller Intl. Airport is nearby so you can deplane and get going on checking off everything on your Mission must-do list.

How much are flights to Mission?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Mission on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $222, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Mission?

The trick to saving a stack of cash on your flight to Mission? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $222 right now, why wait?

Mission Flight Information
Destination airport
Miller Intl.
Destination airport IATA code
MFE
Roundtrip price
$221

Last Minute Hotel Deals in Mission

La Quinta Inn & Suites by Wyndham Mission at West McAllen

La Quinta Inn & Suites by Wyndham Mission at West McAllen

3 out of 5
805 Travis Street Mission TX
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,006 reviews)
"just a nicely staffed clean place to rest your head while away from home ."

Reviewed on Jun 4, 2026

La Quinta Inn & Suites by Wyndham Mission at West McAllen
The Bungalows on Shary, Mission-McAllen

The Bungalows on Shary, Mission-McAllen

2.5 out of 5
3700 Plantation Grove Blvd Mission TX
Stay at this hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions La ...
8.8/10 Excellent! (1,013 reviews)
"The area is beautiful as well as the rooms. I was left waiting for at least 10-15 min while an employee/ mgr excused herself and went to talk to what looked like a new hire? Also, it took us approx 30-40 min to check in. Other than that, the staff was real friendly and we enjoyed our stay and really ..."

Reviewed on Jun 7, 2026

The Bungalows on Shary, Mission-McAllen
Motel 6 Mission, TX

Motel 6 Mission, TX

2 out of 5
1813 E Expressway 83 Mission TX
Stay at this motel in Mission. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.6/10 Excellent! (1,199 reviews)
"It sounds like people where throw a party above me all day long, and it was 2am and there was people just screaming and laughing all night long making it very difficult to rest no respect for the rest of the people there"

Reviewed on Jun 6, 2026

Motel 6 Mission, TX
Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG

Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG

2.5 out of 5
901 S Shary Rd Mission TX
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Popular attractions La Plaza Mall and Cinemark Tinseltown ...
9/10 Wonderful! (1,015 reviews)
"Nice staff"

Reviewed on Jun 6, 2026

Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG
Hampton Inn & Suites Mission

Hampton Inn & Suites Mission

3 out of 5
2505 Victoria Rd Mission TX
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,013 reviews)
"clean rooms and good breakfast"

Reviewed on Jun 1, 2026

Hampton Inn & Suites Mission
SureStay Hotel By Best Western Mission

SureStay Hotel By Best Western Mission

2.5 out of 5
609 East Interstate Highway 2 Mission TX
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free parking, and a fitness center. Popular attractions La Plaza Mall and Mission ...
8/10 Very Good! (755 reviews)
"It’s clean, convenient and affordable. It’s a great option if you’re passing through town"

Reviewed on Jun 5, 2026

SureStay Hotel By Best Western Mission
avid Hotel Mission East Mcallen Area by IHG

avid Hotel Mission East Mcallen Area by IHG

2 out of 5
101 Grapefruit Blvd Mission TX
Stay at this hotel in Mission. Enjoy free breakfast and a 24-hour front desk. Popular attractions La Plaza Mall and Cinemark Tinseltown USA Mission are located ...
8.6/10 Excellent! (51 reviews)
"Good location and good price."

Reviewed on May 31, 2026

avid Hotel Mission East Mcallen Area by IHG
Candlewood Suites Mission East Mcallen Area by IHG

Candlewood Suites Mission East Mcallen Area by IHG

2.5 out of 5
101 Grapefruit Blvd.Suite B. Mission TX
Stay at this hotel in Mission. Enjoy a 24-hour front desk. Popular attractions La Plaza Mall and Cinemark Tinseltown USA Mission are located nearby.
9/10 Wonderful! (23 reviews)
"The overall stay was pretty good. Nice beds, pretty good ac, nice staff, quick an easy check in and check out. Although because the staff mentioned the hotel was newly built it was missing some quality of life features. Such as streaming services on the TV, no Netflix or Hulu unless you connected ..."

Reviewed on Jun 6, 2026

Candlewood Suites Mission East Mcallen Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Comfort Inn Near Medical Center

Comfort Inn Near Medical Center

2.5 out of 5
203 S Shary Rd Mission TX
Book a stay at this business-friendly hotel in Mission. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions La Plaza Mall and Cinemark Tinseltown ...
Comfort Inn Near Medical Center
Hampton Inn & Suites Mission

Hampton Inn & Suites Mission

3 out of 5
2505 Victoria Rd Mission TX
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,013 reviews)
"clean rooms and good breakfast"

Reviewed on Jun 1, 2026

Hampton Inn & Suites Mission
Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG

Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG

2.5 out of 5
901 S Shary Rd Mission TX
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Popular attractions La Plaza Mall and Cinemark Tinseltown ...
9/10 Wonderful! (1,015 reviews)
"Nice staff"

Reviewed on Jun 6, 2026

Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG
La Quinta Inn & Suites by Wyndham Mission at West McAllen

La Quinta Inn & Suites by Wyndham Mission at West McAllen

3 out of 5
805 Travis Street Mission TX
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,006 reviews)
"just a nicely staffed clean place to rest your head while away from home ."

Reviewed on Jun 4, 2026

La Quinta Inn & Suites by Wyndham Mission at West McAllen
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.