Search Cheap Flights to
Mission

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Cheap Flights to Mission

Fall in love at first flight with your vacation to Mission by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Mission on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Mission, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Mission

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Mission with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MFE airport.

What is the cheapest month to fly to Mission?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Mission are in , but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Mission?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find  to choose from for your flight to Mission.

What airport is best to fly into Mission?

When you’re planning your trip to Mission, convenience is the name of the game. Luckily, Mission Miller Intl. Airport is nearby so you can deplane and get going on checking off everything on your Mission must-do list.

How much are flights to Mission?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Mission on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as , you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Mission?

The trick to saving a stack of cash on your flight to Mission? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as  right now, why wait?

Mission Flight Information
Destination airport
Mission
Destination airport IATA code
MFE

Last Minute Hotel Deals in Mission

Motel 6 Mission, TX

Motel 6 Mission, TX

2 out of 5
1813 E Expressway 83, Mission, TX
Stay at this motel in Mission. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.4/10 Very Good! (1,017 reviews)
"Its good"

Reviewed on Sep 28, 2025

Motel 6 Mission, TX
La Quinta Inn & Suites by Wyndham Mission at West McAllen

La Quinta Inn & Suites by Wyndham Mission at West McAllen

3 out of 5
805 Travis Street, Mission, TX
Stay at this 3-star business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,011 reviews)
"This old building has a musty, damp smell in the room. The beds and pillows aren’t as comfortable as the ones in other franchises of the same chain. However, the customer service is excellent."

Reviewed on Sep 21, 2025

La Quinta Inn & Suites by Wyndham Mission at West McAllen
The Bungalows on Shary, Mission-McAllen

The Bungalows on Shary, Mission-McAllen

2.5 out of 5
3700 Plantation Grove Blvd, Mission, TX
Stay at this hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions La ...
8.4/10 Very Good! (938 reviews)
"Annie was awesome. Everyone was so friendly to us"

Reviewed on Sep 22, 2025

The Bungalows on Shary, Mission-McAllen
Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG

Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG

2.5 out of 5
901 S Shary Rd, Mission, TX
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Popular attractions La Plaza Mall and Cinemark Tinseltown ...
8.6/10 Excellent! (1,007 reviews)
"I enjoyed my stay"

Reviewed on Aug 24, 2025

Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG
Shary Inn and Suites

Shary Inn and Suites

2.5 out of 5
203 S Shary Rd, Mission, TX
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (936 reviews)
"Good"

Reviewed on Sep 14, 2025

Shary Inn and Suites
Hampton Inn & Suites Mission

Hampton Inn & Suites Mission

2.5 out of 5
2505 Victoria Rd, Mission, TX
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,009 reviews)
"El chico de recepción muy amable"

Reviewed on Sep 20, 2025

Hampton Inn & Suites Mission
SureStay Hotel By Best Western Mission

SureStay Hotel By Best Western Mission

2.5 out of 5
609 East Interstate Highway 2, Mission, TX
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free parking, and a fitness center. Popular attractions La Plaza Mall and Mission ...
7.8/10 Good! (654 reviews)
Family trip 2025
"Very clean and will be staying there more often and a lot of places to eat close by too"

Reviewed on Sep 23, 2025

SureStay Hotel By Best Western Mission
La Quinta Inn & Suites by Wyndham McAllen La Plaza Mall

La Quinta Inn & Suites by Wyndham McAllen La Plaza Mall

3 out of 5
1120 S 10th St, McAllen, TX
Stay at this 3-star business-friendly hotel in McAllen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,443 reviews)
"Very nice"

Reviewed on Sep 27, 2025

La Quinta Inn & Suites by Wyndham McAllen La Plaza Mall
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Comfort Inn Near Medical Center

Comfort Inn Near Medical Center

2.5 out of 5
203 S Shary Rd, Mission, TX
Book a stay at this business-friendly hotel in Mission. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions La Plaza Mall and Cinemark Tinseltown ...
"The outside was nice. Didn’t really like the lighting in the rooms."

Reviewed on Dec 16, 2020

Comfort Inn Near Medical Center
Hampton Inn & Suites Mission

Hampton Inn & Suites Mission

2.5 out of 5
2505 Victoria Rd, Mission, TX
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,009 reviews)
"El chico de recepción muy amable"

Reviewed on Sep 20, 2025

Hampton Inn & Suites Mission
Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG

Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG

2.5 out of 5
901 S Shary Rd, Mission, TX
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Popular attractions La Plaza Mall and Cinemark Tinseltown ...
8.6/10 Excellent! (1,007 reviews)
"I enjoyed my stay"

Reviewed on Aug 24, 2025

Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG
La Quinta Inn & Suites by Wyndham Mission at West McAllen

La Quinta Inn & Suites by Wyndham Mission at West McAllen

3 out of 5
805 Travis Street, Mission, TX
Stay at this 3-star business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,011 reviews)
"This old building has a musty, damp smell in the room. The beds and pillows aren’t as comfortable as the ones in other franchises of the same chain. However, the customer service is excellent."

Reviewed on Sep 21, 2025

La Quinta Inn & Suites by Wyndham Mission at West McAllen
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.