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Santa Clara

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Santa Clara Flights as Low as $299

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Sat, May 17 - Sun, May 25
MIA
Miami Intl.
PTY
Tocumen Intl.
$299 Roundtrip, found 3 days ago
$299
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, May 17 from Miami Intl. to Tocumen Intl., returning Sun, May 25, priced at $299 found 3 days ago
Delta
Sat, May 17 - Sat, May 24
MIA
Miami Intl.
PTY
Tocumen Intl.
$313 Roundtrip, found 1 day ago
$313
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, May 17 from Miami Intl. to Tocumen Intl., returning Sat, May 24, priced at $313 found 1 day ago
Delta
Tue, Apr 1 - Wed, Apr 23
MIA
Miami Intl.
PTY
Tocumen Intl.
$314 Roundtrip, found 2 days ago
$314
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Apr 1 from Miami Intl. to Tocumen Intl., returning Wed, Apr 23, priced at $314 found 2 days ago
American Airlines
Thu, Oct 23 - Mon, Oct 27
MIA
Miami Intl.
PTY
Tocumen Intl.
$319 Roundtrip, found 21 hours ago
$319
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Thu, Oct 23 from Miami Intl. to Tocumen Intl., returning Mon, Oct 27, priced at $319 found 21 hours ago
Delta
Sat, May 17 - Thu, May 22
MIA
Miami Intl.
PTY
Tocumen Intl.
$320 Roundtrip, found 1 day ago
$320
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, May 17 from Miami Intl. to Tocumen Intl., returning Thu, May 22, priced at $320 found 1 day ago
Delta
Tue, Mar 18 - Wed, Mar 26
MIA
Miami Intl.
PTY
Tocumen Intl.
$335 Roundtrip, found 3 days ago
$335
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Mar 18 from Miami Intl. to Tocumen Intl., returning Wed, Mar 26, priced at $335 found 3 days ago
Copa
Fri, May 16 - Mon, May 26
MIA
Miami Intl.
PTY
Tocumen Intl.
$347 Roundtrip, found 1 day ago
$347
Roundtrip
found 1 day ago
Select Copa flight, departing Fri, May 16 from Miami Intl. to Tocumen Intl., returning Mon, May 26, priced at $347 found 1 day ago
Delta
Mon, Apr 14 - Tue, Apr 29
SAT
San Antonio Intl.
PTY
Tocumen Intl.
$447 Roundtrip, found 4 days ago
$447
Roundtrip
found 4 days ago
Select Delta flight, departing Mon, Apr 14 from San Antonio Intl. to Tocumen Intl., returning Tue, Apr 29, priced at $447 found 4 days ago
United
Sun, Apr 13 - Wed, Apr 30
SAT
San Antonio Intl.
PTY
Tocumen Intl.
$465 Roundtrip, found 4 days ago
$465
Roundtrip
found 4 days ago
Select United flight, departing Sun, Apr 13 from San Antonio Intl. to Tocumen Intl., returning Wed, Apr 30, priced at $465 found 4 days ago
avianca
Thu, Oct 23 - Mon, Oct 27
MIA
Miami Intl.
PTY
Tocumen Intl.
$475 Roundtrip, found 21 hours ago
$475
Roundtrip
found 21 hours ago
Select avianca flight, departing Thu, Oct 23 from Miami Intl. to Tocumen Intl., returning Mon, Oct 27, priced at $475 found 21 hours ago
Copa
Tue, Apr 1 - Wed, Apr 2
MBJ
Sir Donald Sangster Intl.
PTY
Tocumen Intl.
$495 Roundtrip, found 1 day ago
$495
Roundtrip
found 1 day ago
Select Copa flight, departing Tue, Apr 1 from Sir Donald Sangster Intl. to Tocumen Intl., returning Wed, Apr 2, priced at $495 found 1 day ago
United
Sat, Nov 1 - Sun, Nov 16
AUS
Austin-Bergstrom Intl.
PTY
Tocumen Intl.
$503 Roundtrip, found 14 hours ago
$503
Roundtrip
found 14 hours ago
Select United flight, departing Sat, Nov 1 from Austin-Bergstrom Intl. to Tocumen Intl., returning Sun, Nov 16, priced at $503 found 14 hours ago
Delta
Tue, Apr 8 - Tue, May 6
PHX
Sky Harbor Intl.
PTY
Tocumen Intl.
$531 Roundtrip, found 1 day ago
$531
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Apr 8 from Sky Harbor Intl. to Tocumen Intl., returning Tue, May 6, priced at $531 found 1 day ago
United
Mon, Jul 7 - Mon, Aug 4
EWR
Newark Liberty Intl. Airport
PTY
Tocumen Intl.
$611 Roundtrip, found 5 days ago
$611
Roundtrip
found 5 days ago
Select United flight, departing Mon, Jul 7 from Newark Liberty Intl. Airport to Tocumen Intl., returning Mon, Aug 4, priced at $611 found 5 days ago
Copa
Sat, Mar 8 - Sun, Mar 9
GYE
Jose Joaquin de Olmedo Intl.
PTY
Tocumen Intl.
$683 Roundtrip, found 1 day ago
$683
Roundtrip
found 1 day ago
Select Copa flight, departing Sat, Mar 8 from Jose Joaquin de Olmedo Intl. to Tocumen Intl., returning Sun, Mar 9, priced at $683 found 1 day ago
Aeromexico
Thu, Oct 23 - Mon, Oct 27
MIA
Miami Intl.
PTY
Tocumen Intl.
$691 Roundtrip, found 21 hours ago
$691
Roundtrip
found 21 hours ago
Select Aeromexico flight, departing Thu, Oct 23 from Miami Intl. to Tocumen Intl., returning Mon, Oct 27, priced at $691 found 21 hours ago

Cheap Flights to Santa Clara

Fall in love at first flight with your vacation to Santa Clara by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Clara on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Clara, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Clara

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Clara with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the PAC airport.

What is the cheapest month to fly to Santa Clara?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Clara are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Clara?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Clara.

What airport is best to fly into Santa Clara?

When you’re planning your trip to Santa Clara, convenience is the name of the game. Luckily, Santa Clara Scarlett Martinez Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santa Clara must-do list.

How much are flights to Santa Clara?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Clara on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $299, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Clara?

The trick to saving a stack of cash on your flight to Santa Clara? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $299 right now, why wait?

Santa Clara Flight Information
Destination airport
Tocumen Intl.
Destination airport IATA code
PTY
Roundtrip price
$298

Last Minute Hotel Deals in Santa Clara

Villa Botero By Casa Mojito B&B
Villa Botero By Casa Mojito B&B
3 out of 5
Calle Central, 5, Rio Hato, Cocle
The price is $132 per night from Mar 9 to Mar 10
$132
includes taxes & fees
Mar 9 - Mar 10
Stay at this 3-star golf B&B in Rio Hato. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Playa Blanca and Farallón Beach are located ...
9.6/10 Exceptional! (53 reviews)
"Christophe was an amazing host! Very kind to us, and was there for any questions we had. The cats were very friendly around the property, and the breakfast was delicious!"

Reviewed on Dec 16, 2024

Villa Botero By Casa Mojito B&B
Las Sirenas de Santa Clara
Las Sirenas de Santa Clara
3 out of 5
Carretera Interamericana Km.113, Rio Hato, Cocle
Stay at this 3-star beach villa in Rio Hato. Enjoy free WiFi, free parking, and a beach locale. Popular attractions Playa Blanca and Farallón Beach are located ...
10/10 Exceptional! (1 review)
Excelente lugar para Familia - Enfocarse en eso!!
"Todo estuvo perfecto, solo pienso que si deben controlar un poco las personas que se hospedan en las cabañas, ejemplo: todas las cabañas que estábamos eramos familias con niños solo una donde todos eran jóvenes, esa cabaña tenia música y bulla hasta altas horas de la noche y aunque varios de las ..."

Reviewed on May 2, 2017

Get rates
Las Sirenas de Santa Clara
Gran Evenia Bijao & Convention Center
Gran Evenia Bijao & Convention Center
3.5 out of 5
Carretera Interamericana km 108, Rio Hato
The price is $175 per night from Mar 7 to Mar 8
$175
includes taxes & fees
Mar 7 - Mar 8
Stay at this 3.5-star beach hotel in Rio Hato. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
7.6/10 Good! (807 reviews)
"Divino!! Todo muy bien. Buena comida. Hermosa playa. Bonitas instalaciones"

Reviewed on Feb 25, 2025

Gran Evenia Bijao & Convention Center
Hotel Riu Playa Blanca - All Inclusive
Hotel Riu Playa Blanca - All Inclusive
3.5 out of 5
Finca 43.668, Rio Hato, Cocle
Stay at this 3.5-star beach property in Rio Hato. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8/10 Very Good! (1,003 reviews)
"We ended our family vacation to Panama with this all-inclusive stay at Riu Playa Blanca. In general our stay was quite pleasant. The hotel, our room and all areas are quite clean. The staff are lovely and quite good at their jobs. And lastly, since it's an all-inclusive, I must mention the food. ..."

Reviewed on Feb 26, 2025

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Hotel Riu Playa Blanca - All Inclusive
Playa Blanca Beach Resort - All Inclusive
Playa Blanca Beach Resort - All Inclusive
4 out of 5
115 Km Via Interamericana, Rio Hato, Cocle
The price is $191 per night from Apr 2 to Apr 3
$191
includes taxes & fees
Apr 2 - Apr 3
Stay at this 4-star beach property in Rio Hato. Enjoy free breakfast, free parking, and 3 outdoor pools. Our guests praise the property condition in our reviews. ...
6.6/10 (972 reviews)
"The room was very clean and had a kitchen. The balcony was large and had chairs to sit and relax. The area is clean and quiet."

Reviewed on Feb 28, 2025

Playa Blanca Beach Resort - All Inclusive
The Buenaventura Golf & Beach Resort Panama, Autograph Collection
The Buenaventura Golf & Beach Resort Panama, Autograph Collection
5 out of 5
340 Calle 3ra Buenaventura, Buenaventura Beach Community, El Chiru, Cocle
The price is $271 per night from Apr 5 to Apr 6
$271
includes taxes & fees
Apr 5 - Apr 6
Stay at this 5-star luxury resort in El Chiru. Enjoy free WiFi, free parking, and 12 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (609 reviews)
Excellent
"Todaa las personas en el hotel son super Amables y Serviciales. La Comida muy rica y de Calidad ."

Reviewed on Jan 3, 2025

The Buenaventura Golf & Beach Resort Panama, Autograph Collection
Grand Decameron Panama, A Trademark All Inclusive Resort
Grand Decameron Panama, A Trademark All Inclusive Resort
3.5 out of 5
Avenida Principal Farallon. Kilometro 11, Carretera Interamericana - Penonome, Rio Hato, Cocle
The price is $201 per night from Mar 9 to Mar 10
$201
includes taxes & fees
Mar 9 - Mar 10
Stay at this 3.5-star beach property in Rio Hato. Enjoy free breakfast, free parking, and 6 outdoor pools. Popular attractions Playa Blanca and Farallón Beach ...
7.2/10 Good! (968 reviews)
"There were lots of options for pools, restaurants and bars. It would have been nice if more staff had a basic understanding of English."

Reviewed on Feb 12, 2025

Grand Decameron Panama, A Trademark All Inclusive Resort
Hotel Campestre
Hotel Campestre
3 out of 5
Calle El Hato, El Valle de Anton
The price is $134 per night from Mar 7 to Mar 8
$134
includes taxes & fees
Mar 7 - Mar 8
Stay at this 3-star hotel in El Valle de Anton. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Square Trees Nature Trail and Anton ...
8.2/10 Very Good! (228 reviews)
Beautiful Spot in El Valle
"Took a quick trip up to El Valle during our stay in Panama on the beach. What a beautiful location, the grounds are so lush, and the scenery so beautiful. We enjoyed drinks down at the brewery and a lovely dinner and breakfast on site. The rooms are simple, but clean and had everything we ..."

Reviewed on Mar 5, 2025

Hotel Campestre
See all 573 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.