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Santa Clara

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Santa Clara Flights as Low as $257

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Copa
Sat, Oct 17 - Tue, Oct 27
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$257 Roundtrip, found 2 hours ago
$257
Roundtrip
found 2 hours ago
Select Copa flight, departing Sat, Oct 17 from Juan Santamaría Intl. to Tocumen Intl., returning Tue, Oct 27, priced at $257 found 2 hours ago
Copa
Tue, Oct 20 - Sun, Oct 25
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$264 Roundtrip, found 6 hours ago
$264
Roundtrip
found 6 hours ago
Select Copa flight, departing Tue, Oct 20 from Juan Santamaría Intl. to Tocumen Intl., returning Sun, Oct 25, priced at $264 found 6 hours ago
Copa
Sat, Oct 17 - Tue, Oct 27
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$275 Roundtrip, found 2 hours ago
$275
Roundtrip
found 2 hours ago
Select Copa flight, departing Sat, Oct 17 from Juan Santamaría Intl. to Tocumen Intl., returning Tue, Oct 27, priced at $275 found 2 hours ago
Copa
Sat, Oct 17 - Tue, Oct 27
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$282 Roundtrip, found 2 hours ago
$282
Roundtrip
found 2 hours ago
Select Copa flight, departing Sat, Oct 17 from Juan Santamaría Intl. to Tocumen Intl., returning Tue, Oct 27, priced at $282 found 2 hours ago
Copa
Sat, Oct 17 - Tue, Oct 27
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$284 Roundtrip, found 2 hours ago
$284
Roundtrip
found 2 hours ago
Select Copa flight, departing Sat, Oct 17 from Juan Santamaría Intl. to Tocumen Intl., returning Tue, Oct 27, priced at $284 found 2 hours ago
avianca
Tue, Oct 6 - Tue, Oct 6
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$290 Roundtrip, found 15 hours ago
$290
Roundtrip
found 15 hours ago
Select avianca flight, departing Tue, Oct 6 from Juan Santamaría Intl. to Tocumen Intl., returning Tue, Oct 6, priced at $290 found 15 hours ago
Copa
Tue, Oct 6 - Tue, Oct 6
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$292 Roundtrip, found 15 hours ago
$292
Roundtrip
found 15 hours ago
Select Copa flight, departing Tue, Oct 6 from Juan Santamaría Intl. to Tocumen Intl., returning Tue, Oct 6, priced at $292 found 15 hours ago
avianca
Tue, Nov 17 - Sun, Nov 22
GUA
La Aurora Intl.
PTY
Tocumen Intl.
$410 Roundtrip, found 1 day ago
$410
Roundtrip
found 1 day ago
Select avianca flight, departing Tue, Nov 17 from La Aurora Intl. to Tocumen Intl., returning Sun, Nov 22, priced at $410 found 1 day ago
United
Wed, Jan 27 - Mon, Feb 1
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$417 Roundtrip, found 2 hours ago
$417
Roundtrip
found 2 hours ago
Select United flight, departing Wed, Jan 27 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Mon, Feb 1, priced at $417 found 2 hours ago
United
Tue, Mar 9 - Wed, Mar 17
SEA
Seattle - Tacoma Intl.
PTY
Tocumen Intl.
$565 Roundtrip, found 1 day ago
$565
Roundtrip
found 1 day ago
Select United flight, departing Tue, Mar 9 from Seattle - Tacoma Intl. to Tocumen Intl., returning Wed, Mar 17, priced at $565 found 1 day ago
Delta
Fri, Oct 16 - Thu, Oct 22
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$580 Roundtrip, found 1 day ago
$580
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Oct 16 from Hartsfield-Jackson Atlanta Intl. to Tocumen Intl., returning Thu, Oct 22, priced at $580 found 1 day ago
American Airlines
Mon, Jan 18 - Thu, Jan 21
SEA
Seattle - Tacoma Intl.
PTY
Tocumen Intl.
$586 Roundtrip, found 1 day ago
$586
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Jan 18 from Seattle - Tacoma Intl. to Tocumen Intl., returning Thu, Jan 21, priced at $586 found 1 day ago
Delta
Tue, Apr 13 - Wed, Apr 28
AUS
Austin-Bergstrom Intl.
PTY
Tocumen Intl.
$607 Roundtrip, found 5 days ago
$607
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Apr 13 from Austin-Bergstrom Intl. to Tocumen Intl., returning Wed, Apr 28, priced at $607 found 5 days ago
Aeromexico
Wed, Nov 18 - Wed, Nov 25
GUA
La Aurora Intl.
PTY
Tocumen Intl.
$638 Roundtrip, found 1 day ago
$638
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Wed, Nov 18 from La Aurora Intl. to Tocumen Intl., returning Wed, Nov 25, priced at $638 found 1 day ago
Delta
Mon, Nov 30 - Mon, Dec 7
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$639 Roundtrip, found 6 days ago
$639
Roundtrip
found 6 days ago
Select Delta flight, departing Mon, Nov 30 from John F. Kennedy Intl. to Tocumen Intl., returning Mon, Dec 7, priced at $639 found 6 days ago
Alaska Airlines
Mon, Jan 18 - Wed, Jan 27
PAE
Seattle Paine Field Intl. Airport
PTY
Tocumen Intl.
$920 Roundtrip, found 2 days ago
$920
Roundtrip
found 2 days ago
Select Alaska Airlines flight, departing Mon, Jan 18 from Seattle Paine Field Intl. Airport to Tocumen Intl., returning Wed, Jan 27, priced at $920 found 2 days ago

Cheap Flights to Santa Clara

Fall in love at first flight with your vacation to Santa Clara by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Clara on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Clara, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Clara

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Clara with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the PAC airport.

What is the cheapest month to fly to Santa Clara?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Clara are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Clara?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Clara.

What airport is best to fly into Santa Clara?

When you’re planning your trip to Santa Clara, convenience is the name of the game. Luckily, Santa Clara Scarlett Martinez Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santa Clara must-do list.

How much are flights to Santa Clara?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Clara on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $257, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Clara?

The trick to saving a stack of cash on your flight to Santa Clara? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $257 right now, why wait?

Santa Clara Flight Information
Destination airport
Tocumen Intl.
Destination airport IATA code
PTY
Roundtrip price
$256

Last Minute Hotel Deals in Santa Clara

Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Calle Central, 5 Rio Hato Cocle
Book a stay at this golf B&B in Rio Hato. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Playa Blanca and Farallón Beach are located ...
9.8/10 Exceptional! (69 reviews)
"Christophe and his family were amazing hosts. The breakfast was incredible and fit for a king. The grounds, room and pool were decorated beautifully and very well maintained. We would stay here again in a heartbeat. We highly recommend this place."

Reviewed on Jun 17, 2026

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Villa Botero By Casa Mojito B&B
Gran Evenia Bijao - All Inclusive

Gran Evenia Bijao - All Inclusive

3.5 out of 5
Carretera Interamericana km 108, guias de Anton Rio Hato Coclé
Book a stay at this beach hotel in Rio Hato. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
8.2/10 Very Good! (1,008 reviews)
"This is a very nice place for people with kids or want to party all day long. Noises all day long, no matter where you go. Very loud music, animation, group events and ongoing constructions. In fact, it was so loud, we couldn't hear the big excavator working right next to us at the beach chair. The ..."

Reviewed on Sep 25, 2026

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Gran Evenia Bijao - All Inclusive
Hotel Riu Playa Blanca - All Inclusive

Hotel Riu Playa Blanca - All Inclusive

3.5 out of 5
Finca 43.668 Rio Hato Cocle
Book a stay at this golf property in Rio Hato. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8.2/10 Very Good! (1,004 reviews)
"."

Reviewed on Sep 25, 2026

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Hotel Riu Playa Blanca - All Inclusive
Grand Decameron Panama, A Trademark Resort

Grand Decameron Panama, A Trademark Resort

3.5 out of 5
Avenida Principal Farallon Kilometro 115 Rio Hato Cocle
Book a stay at this beach property in Rio Hato. Enjoy free parking, 6 outdoor pools, and a full-service spa. Popular attractions Playa Blanca and Farallón Beach ...
7.4/10 Good! (1,003 reviews)
"Día 1 : hacer check-in tomo 45 minutos , hora de la cena no llegaba a la mesa a ofrecer las bebidas nos tocó un cubierto sucio. El joven del bar la actitud debe mejorar . Día 2 : hacer la reservación en un restaurante es imposible el día que pedimos solo nos dieron hasta las 9:30 pm para cenar como ..."

Reviewed on Sep 25, 2026

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Grand Decameron Panama, A Trademark Resort
Playa Blanca Beach Resort - All Inclusive

Playa Blanca Beach Resort - All Inclusive

4 out of 5
115 Km Via Interamericana Rio Hato Cocle
Book a stay at this beach property in Rio Hato. Enjoy free breakfast, free parking, and 3 outdoor pools. Popular attractions Playa Blanca and Farallón Beach ...
7/10 Good! (262 reviews)
"Muy buena atención al cliente, en especial en recepción del town center, muy buen trato en todo, la comida muy buena y en general todo bien."

Reviewed on Sep 21, 2026

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Playa Blanca Beach Resort - All Inclusive
The Buenaventura Golf & Beach Resort Panama, Autograph Collection

The Buenaventura Golf & Beach Resort Panama, Autograph Collection

5 out of 5
340 Calle 3ra Buenaventura El Chiru Cocle
Book a stay at this luxury resort in El Chiru. Enjoy free WiFi, free parking, and 12 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
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The Buenaventura Golf & Beach Resort Panama, Autograph Collection
Hotel La Compania Del Valle

Hotel La Compania Del Valle

5 out of 5
C. El Ciclo El Valle de Anton
Book a stay at this luxury hotel in El Valle de Anton. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Anton Valley Historical and Cultural ...
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Hotel La Compania Del Valle
The Golden Frog Inn

The Golden Frog Inn

3 out of 5
Calle Las Veraneras El Valle de Anton Panama
Stay at this hotel in El Valle de Anton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.6/10 Exceptional! (304 reviews)
"On a walk on a side road just outside of town my wife tripped and fell face first into the pavement. She sprained her ankle and badly bruised her entire face and her nose was broken in a few places. A stranger gave us a lift back to the hotel. My wife limped into the lobby, Her face wa bleeding and ..."

Reviewed on Sep 25, 2026

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The Golden Frog Inn
See all 503 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.