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Santa Clara

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Santa Clara Flights as Low as $472

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

avianca
Mon, Jul 13 - Fri, Jul 17
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$472 Roundtrip, found 2 days ago
$472
Roundtrip
found 2 days ago
Select avianca flight, departing Mon, Jul 13 from John F. Kennedy Intl. to Tocumen Intl., returning Fri, Jul 17, priced at $472 found 2 days ago
United
Sun, Oct 25 - Fri, Oct 30
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$510 Roundtrip, found 1 hour ago
$510
Roundtrip
found 1 hour ago
Select United flight, departing Sun, Oct 25 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Fri, Oct 30, priced at $510 found 1 hour ago
avianca
Mon, Jul 13 - Tue, Jul 14
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$531 Roundtrip, found 2 days ago
$531
Roundtrip
found 2 days ago
Select avianca flight, departing Mon, Jul 13 from John F. Kennedy Intl. to Tocumen Intl., returning Tue, Jul 14, priced at $531 found 2 days ago
avianca
Mon, Jul 13 - Tue, Jul 14
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$533 Roundtrip, found 2 days ago
$533
Roundtrip
found 2 days ago
Select avianca flight, departing Mon, Jul 13 from John F. Kennedy Intl. to Tocumen Intl., returning Tue, Jul 14, priced at $533 found 2 days ago
avianca
Mon, Jul 13 - Tue, Jul 14
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$534 Roundtrip, found 2 days ago
$534
Roundtrip
found 2 days ago
Select avianca flight, departing Mon, Jul 13 from John F. Kennedy Intl. to Tocumen Intl., returning Tue, Jul 14, priced at $534 found 2 days ago
United
Wed, Oct 28 - Wed, Nov 4
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$536 Roundtrip, found 12 hours ago
$536
Roundtrip
found 12 hours ago
Select United flight, departing Wed, Oct 28 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Wed, Nov 4, priced at $536 found 12 hours ago
avianca
Mon, Jul 13 - Tue, Jul 14
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$544 Roundtrip, found 2 days ago
$544
Roundtrip
found 2 days ago
Select avianca flight, departing Mon, Jul 13 from John F. Kennedy Intl. to Tocumen Intl., returning Tue, Jul 14, priced at $544 found 2 days ago
Copa
Wed, Jul 29 - Tue, Aug 4
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$551 Roundtrip, found 12 hours ago
$551
Roundtrip
found 12 hours ago
Select Copa flight, departing Wed, Jul 29 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Tue, Aug 4, priced at $551 found 12 hours ago
Copa
Mon, Aug 24 - Mon, Sep 7
AUS
Austin-Bergstrom Intl.
PTY
Tocumen Intl.
$560 Roundtrip, found 15 hours ago
$560
Roundtrip
found 15 hours ago
Select Copa flight, departing Mon, Aug 24 from Austin-Bergstrom Intl. to Tocumen Intl., returning Mon, Sep 7, priced at $560 found 15 hours ago
United
Sun, Oct 25 - Fri, Oct 30
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$563 Roundtrip, found 1 hour ago
$563
Roundtrip
found 1 hour ago
Select United flight, departing Sun, Oct 25 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Fri, Oct 30, priced at $563 found 1 hour ago
Delta
Sat, Sep 19 - Sat, Oct 3
AUS
Austin-Bergstrom Intl.
PTY
Tocumen Intl.
$565 Roundtrip, found 3 hours ago
$565
Roundtrip
found 3 hours ago
Select Delta flight, departing Sat, Sep 19 from Austin-Bergstrom Intl. to Tocumen Intl., returning Sat, Oct 3, priced at $565 found 3 hours ago
American Airlines
Sat, Sep 19 - Sat, Oct 3
AUS
Austin-Bergstrom Intl.
PTY
Tocumen Intl.
$569 Roundtrip, found 3 hours ago
$569
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Sat, Sep 19 from Austin-Bergstrom Intl. to Tocumen Intl., returning Sat, Oct 3, priced at $569 found 3 hours ago
Delta
Mon, Aug 10 - Thu, Aug 13
RDU
Raleigh - Durham Intl.
PTY
Tocumen Intl.
$587 Roundtrip, found 1 day ago
$587
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Aug 10 from Raleigh - Durham Intl. to Tocumen Intl., returning Thu, Aug 13, priced at $587 found 1 day ago
United
Tue, Oct 27 - Tue, Nov 17
MSP
Minneapolis - St. Paul Intl.
PTY
Tocumen Intl.
$705 Roundtrip, found 1 day ago
$705
Roundtrip
found 1 day ago
Select United flight, departing Tue, Oct 27 from Minneapolis - St. Paul Intl. to Tocumen Intl., returning Tue, Nov 17, priced at $705 found 1 day ago
United
Thu, Jul 9 - Tue, Jul 14
OMA
Eppley Field
PTY
Tocumen Intl.
$793 Roundtrip, found 1 hour ago
$793
Roundtrip
found 1 hour ago
Select United flight, departing Thu, Jul 9 from Eppley Field to Tocumen Intl., returning Tue, Jul 14, priced at $793 found 1 hour ago
Aeromexico
Mon, Jan 18 - Sun, Jan 31
AUS
Austin-Bergstrom Intl.
PTY
Tocumen Intl.
$877 Roundtrip, found 23 hours ago
$877
Roundtrip
found 23 hours ago
Select Aeromexico flight, departing Mon, Jan 18 from Austin-Bergstrom Intl. to Tocumen Intl., returning Sun, Jan 31, priced at $877 found 23 hours ago

Cheap Flights to Santa Clara

Fall in love at first flight with your vacation to Santa Clara by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Clara on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Clara, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Clara

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Clara with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the PAC airport.

What is the cheapest month to fly to Santa Clara?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Clara are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Clara?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Clara.

What airport is best to fly into Santa Clara?

When you’re planning your trip to Santa Clara, convenience is the name of the game. Luckily, Santa Clara Scarlett Martinez Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santa Clara must-do list.

How much are flights to Santa Clara?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Clara on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $472, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Clara?

The trick to saving a stack of cash on your flight to Santa Clara? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $472 right now, why wait?

Santa Clara Flight Information
Destination airport
Tocumen Intl.
Destination airport IATA code
PTY
Roundtrip price
$471

Last Minute Hotel Deals in Santa Clara

Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Calle Central, 5 Rio Hato Cocle
Book a stay at this golf B&B in Rio Hato. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Playa Blanca and Santa Clara Beach are ...
9.8/10 Exceptional! (69 reviews)
"Christophe and his family were amazing hosts. The breakfast was incredible and fit for a king. The grounds, room and pool were decorated beautifully and very well maintained. We would stay here again in a heartbeat. We highly recommend this place."

Reviewed on Jun 17, 2026

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Villa Botero By Casa Mojito B&B
Gran Evenia Bijao - All Inclusive

Gran Evenia Bijao - All Inclusive

3.5 out of 5
Carretera Interamericana km 108, guias de Anton Rio Hato Coclé
Book a stay at this beach hotel in Rio Hato. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
8.2/10 Very Good! (1,000 reviews)
"La comida excelente, quedamos súper satisfechos. Sería excelente que tuvieran alguna otra dinámica en la noche para niños, cine o teatro. Y el snack de la madrugada también seria bueno que estuviera más completo, la comida estaba muy dura, y poquitas opciones. Pero por lo demás todo estuvo excelente, ..."

Reviewed on Jun 22, 2026

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Gran Evenia Bijao - All Inclusive
Hotel Riu Playa Blanca - All Inclusive

Hotel Riu Playa Blanca - All Inclusive

3.5 out of 5
Finca 43.668 Rio Hato Cocle
Book a stay at this beach property in Rio Hato. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8/10 Very Good! (1,002 reviews)
"AC was well maintained"

Reviewed on Jun 27, 2026

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Hotel Riu Playa Blanca - All Inclusive
Grand Decameron Panama, A Trademark All Inclusive Resort

Grand Decameron Panama, A Trademark All Inclusive Resort

3.5 out of 5
Avenida Principal Farallon Kilometro 115 Rio Hato Cocle
Book a stay at this beach property in Rio Hato. Enjoy free parking, 6 outdoor pools, and a full-service spa. Popular attractions Playa Blanca and Santa Clara ...
7.4/10 Good! (1,000 reviews)
"The staff is kind and helpful...extremely."

Reviewed on Jun 19, 2026

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Grand Decameron Panama, A Trademark All Inclusive Resort
Playa Blanca Beach Resort - All Inclusive

Playa Blanca Beach Resort - All Inclusive

4 out of 5
115 Km Via Interamericana Rio Hato Cocle
Book a stay at this beach property in Rio Hato. Enjoy free breakfast, free parking, and 3 outdoor pools. Popular attractions Playa Blanca and Santa Clara Beach ...
6.8/10 (235 reviews)
"My experience wasn't pleasant when I checked in. One member of the hotel who approached me was very aggressive trying to show us the hotel, for some kind of membership, and because, we refused to do it, didn't let us do early check in and wait at the lobby for an hour and a half or I had to pay $12:00 ..."

Reviewed on Jun 26, 2026

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Playa Blanca Beach Resort - All Inclusive
The Buenaventura Golf & Beach Resort Panama, Autograph Collection

The Buenaventura Golf & Beach Resort Panama, Autograph Collection

5 out of 5
340 Calle 3ra Buenaventura El Chiru Cocle
Book a stay at this luxury resort in El Chiru. Enjoy free WiFi, free parking, and 12 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (754 reviews)
"Ok"

Reviewed on Jun 22, 2026

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The Buenaventura Golf & Beach Resort Panama, Autograph Collection
Hotel La Compania Del Valle

Hotel La Compania Del Valle

5 out of 5
C. El Ciclo El Valle de Anton
Book a stay at this luxury hotel in El Valle de Anton. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Anton Valley Historical and Cultural ...
9.8/10 Exceptional! (122 reviews)
"The statues are unique, the property and the room beautiful, restaurants i gave mixed reviews, the toilet paper needs to be changed but overall a good stay and the staff are super nice…"

Reviewed on Jun 15, 2026

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Hotel La Compania Del Valle
The Golden Frog Inn

The Golden Frog Inn

3 out of 5
Calle Las Veraneras El Valle de Anton Panama
Stay at this hotel in El Valle de Anton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.6/10 Exceptional! (282 reviews)
"I love it! It was clean, the staff was friendly and surprisingly spoke English very well, which was great for me as I’m not a Spanish speaker. The grounds were so beautiful with butterflies and hummingbirds all over the place. I didn’t go in the pool, but it looked very inviting. The complementary ..."

Reviewed on Jun 20, 2026

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The Golden Frog Inn
See all 505 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.