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Santa Clara

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Santa Clara Flights as Low as $268

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Copa
Tue, Jun 30 - Thu, Jul 9
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$268 Roundtrip, found 5 hours ago
$268
Roundtrip
found 5 hours ago
Select Copa flight, departing Tue, Jun 30 from Juan Santamaría Intl. to Tocumen Intl., returning Thu, Jul 9, priced at $268 found 5 hours ago
Copa
Tue, Jun 30 - Thu, Jul 9
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$273 Roundtrip, found 5 hours ago
$273
Roundtrip
found 5 hours ago
Select Copa flight, departing Tue, Jun 30 from Juan Santamaría Intl. to Tocumen Intl., returning Thu, Jul 9, priced at $273 found 5 hours ago
Copa
Wed, May 13 - Wed, May 20
MIA
Miami Intl.
PTY
Tocumen Intl.
$285 Roundtrip, found 1 hour ago
$285
Roundtrip
found 1 hour ago
Select Copa flight, departing Wed, May 13 from Miami Intl. to Tocumen Intl., returning Wed, May 20, priced at $285 found 1 hour ago
avianca
Tue, Jun 30 - Thu, Jul 9
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$294 Roundtrip, found 5 hours ago
$294
Roundtrip
found 5 hours ago
Select avianca flight, departing Tue, Jun 30 from Juan Santamaría Intl. to Tocumen Intl., returning Thu, Jul 9, priced at $294 found 5 hours ago
Copa
Wed, May 13 - Wed, May 20
MIA
Miami Intl.
PTY
Tocumen Intl.
$295 Roundtrip, found 1 hour ago
$295
Roundtrip
found 1 hour ago
Select Copa flight, departing Wed, May 13 from Miami Intl. to Tocumen Intl., returning Wed, May 20, priced at $295 found 1 hour ago
avianca
Tue, Jun 30 - Thu, Jul 9
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$297 Roundtrip, found 5 hours ago
$297
Roundtrip
found 5 hours ago
Select avianca flight, departing Tue, Jun 30 from Juan Santamaría Intl. to Tocumen Intl., returning Thu, Jul 9, priced at $297 found 5 hours ago
Copa
Wed, May 13 - Wed, May 20
MIA
Miami Intl.
PTY
Tocumen Intl.
$305 Roundtrip, found 1 hour ago
$305
Roundtrip
found 1 hour ago
Select Copa flight, departing Wed, May 13 from Miami Intl. to Tocumen Intl., returning Wed, May 20, priced at $305 found 1 hour ago
United
Wed, Apr 8 - Wed, Apr 15
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$320 Roundtrip, found 11 hours ago
$320
Roundtrip
found 11 hours ago
Select United flight, departing Wed, Apr 8 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Wed, Apr 15, priced at $320 found 11 hours ago
United
Fri, Apr 10 - Tue, Apr 14
MIA
Miami Intl.
PTY
Tocumen Intl.
$320 Roundtrip, found 6 hours ago
$320
Roundtrip
found 6 hours ago
Select United flight, departing Fri, Apr 10 from Miami Intl. to Tocumen Intl., returning Tue, Apr 14, priced at $320 found 6 hours ago
American Airlines
Wed, Oct 28 - Wed, Nov 4
MIA
Miami Intl.
PTY
Tocumen Intl.
$352 Roundtrip, found 8 hours ago
$352
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Oct 28 from Miami Intl. to Tocumen Intl., returning Wed, Nov 4, priced at $352 found 8 hours ago
Delta
Fri, May 1 - Thu, May 14
AUS
Austin-Bergstrom Intl.
PTY
Tocumen Intl.
$385 Roundtrip, found 10 hours ago
$385
Roundtrip
found 10 hours ago
Select Delta flight, departing Fri, May 1 from Austin-Bergstrom Intl. to Tocumen Intl., returning Thu, May 14, priced at $385 found 10 hours ago
Delta
Tue, May 5 - Tue, May 12
DAL
Love Field
PTY
Tocumen Intl.
$467 Roundtrip, found 11 hours ago
$467
Roundtrip
found 11 hours ago
Select Delta flight, departing Tue, May 5 from Love Field to Tocumen Intl., returning Tue, May 12, priced at $467 found 11 hours ago
avianca
Fri, May 8 - Fri, May 15
DFW
Dallas-Fort Worth Intl.
PTY
Tocumen Intl.
$479 Roundtrip, found 11 hours ago
$479
Roundtrip
found 11 hours ago
Select avianca flight, departing Fri, May 8 from Dallas-Fort Worth Intl. to Tocumen Intl., returning Fri, May 15, priced at $479 found 11 hours ago
United
Mon, Apr 27 - Wed, Apr 29
IAD
Washington Dulles Intl.
PTY
Tocumen Intl.
$490 Roundtrip, found 1 day ago
$490
Roundtrip
found 1 day ago
Select United flight, departing Mon, Apr 27 from Washington Dulles Intl. to Tocumen Intl., returning Wed, Apr 29, priced at $490 found 1 day ago
Delta
Tue, Apr 28 - Thu, May 14
SAT
San Antonio Intl.
PTY
Tocumen Intl.
$571 Roundtrip, found 13 hours ago
$571
Roundtrip
found 13 hours ago
Select Delta flight, departing Tue, Apr 28 from San Antonio Intl. to Tocumen Intl., returning Thu, May 14, priced at $571 found 13 hours ago
Aeromexico
Fri, May 8 - Fri, May 15
DFW
Dallas-Fort Worth Intl.
PTY
Tocumen Intl.
$971 Roundtrip, found 11 hours ago
$971
Roundtrip
found 11 hours ago
Select Aeromexico flight, departing Fri, May 8 from Dallas-Fort Worth Intl. to Tocumen Intl., returning Fri, May 15, priced at $971 found 11 hours ago

Cheap Flights to Santa Clara

Fall in love at first flight with your vacation to Santa Clara by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Clara on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Clara, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Clara

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Clara with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the PAC airport.

What is the cheapest month to fly to Santa Clara?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Clara are in June, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Clara?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Clara.

What airport is best to fly into Santa Clara?

When you’re planning your trip to Santa Clara, convenience is the name of the game. Luckily, Santa Clara Scarlett Martinez Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santa Clara must-do list.

How much are flights to Santa Clara?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Clara on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $268, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Clara?

The trick to saving a stack of cash on your flight to Santa Clara? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $268 right now, why wait?

Santa Clara Flight Information
Destination airport
Tocumen Intl.
Destination airport IATA code
PTY
Roundtrip price
$268

Last Minute Hotel Deals in Santa Clara

Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Calle Central, 5 Rio Hato Cocle
Book a stay at this golf B&B in Rio Hato. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Playa Blanca and Santa Clara Beach are ...
9.8/10 Exceptional! (64 reviews)
Beautiful grounds, flowers , trees and palms. The casita was perfect, clean and cosy. Loved loved loved the breakfasts!

Reviewed on Jan 26, 2026

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Villa Botero By Casa Mojito B&B
Gran Evenia Bijao & Convention Center

Gran Evenia Bijao & Convention Center

3.5 out of 5
Carretera Interamericana km 108 Rio Hato
Book a stay at this beach hotel in Rio Hato. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
8.2/10 Very Good! (1,014 reviews)
Horrible customer service, tried calling to cancel as our flights to Panama were cancelled and they had no number to call, the number given was a house number. Expedia tried calling and no answer in the end we lost out on our money, we lost out on the hotel.

Reviewed on Mar 9, 2026

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Gran Evenia Bijao & Convention Center
Hotel Riu Playa Blanca - All Inclusive

Hotel Riu Playa Blanca - All Inclusive

3.5 out of 5
Finca 43.668 Rio Hato Cocle
Book a stay at this beach property in Rio Hato. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8/10 Very Good! (1,004 reviews)
The property is clean, the beach is beautiful, pools are nice and food was good. Had an oceanfront view which was perfect. The things that lacked for us was fridge refills every two days, if you called in between then never return unless you call. Room cleaning was mediocre if they showed up each ...

Reviewed on Mar 6, 2026

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Hotel Riu Playa Blanca - All Inclusive
Grand Decameron Panama, A Trademark All Inclusive Resort

Grand Decameron Panama, A Trademark All Inclusive Resort

3.5 out of 5
Avenida Principal Farallon Kilometro 115 Rio Hato Cocle
Book a stay at this beach property in Rio Hato. Enjoy free parking, 6 outdoor pools, and a full-service spa. Popular attractions Playa Blanca and Farallón Beach ...
7.2/10 Good! (1,004 reviews)
Good place but the room was a little bit dirty. The staff were very friendly and helpful.

Reviewed on Mar 6, 2026

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Grand Decameron Panama, A Trademark All Inclusive Resort
The Buenaventura Golf & Beach Resort Panama, Autograph Collection

The Buenaventura Golf & Beach Resort Panama, Autograph Collection

5 out of 5
340 Calle 3ra Buenaventura El Chiru Cocle
Book a stay at this luxury resort in El Chiru. Enjoy free WiFi, free parking, and 12 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (721 reviews)
The property is beautiful and our kids loved their time in the many pools - as well as in the ocean! My one minor complaint is that the shower leaked out the bottom of the door - otherwise, everything was great!

Reviewed on Mar 8, 2026

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The Buenaventura Golf & Beach Resort Panama, Autograph Collection
Hotel La Compania Del Valle

Hotel La Compania Del Valle

5 out of 5
C. El Ciclo El Valle de Anton
Book a stay at this luxury hotel in El Valle de Anton. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Anton Valley Historical and Cultural ...
9.8/10 Exceptional! (96 reviews)
We wish we could have had time to use the spa, but not on this trip. The property was stunning, the pools were perfect, the complimentary happy hour was a very pleasant surprise, the food at Fuego was amazing, the complimentary breakfasts were the best among the 4 hotels we stayed at on our trip. ...

Reviewed on Mar 8, 2026

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Hotel La Compania Del Valle
Gran Evenia Bijao - All Inclusive

Gran Evenia Bijao - All Inclusive

4.5 out of 5
Carretera Interamericana km 108, guias de Anton Rio Hato Coclé
Book a stay at this luxury hotel in Rio Hato. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Playa Blanca and Santa Clara Beach are located ...
7.4/10 Good! (1,003 reviews)
Receptionist was very serious, employees should look happy as they are enjoying their job.

Reviewed on Mar 8, 2026

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Gran Evenia Bijao - All Inclusive
The Golden Frog Inn

The Golden Frog Inn

3 out of 5
Calle Las Veraneras El Valle de Anton Panama
Stay at this hotel in El Valle de Anton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.6/10 Exceptional! (246 reviews)
The hotel is beautifully located surrounded by a tropical garden. We had a luxury room with a pretty view but to get there we had to climb very steep steps. The food was very good but the dinner/lunch menu was the same the 4 days we stayed there.

Reviewed on Mar 8, 2026

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The Golden Frog Inn
See all 543 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.