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Santa Isabel

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Santa Isabel Flights as Low as $330

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Copa
Wed, Oct 16 - Sat, Oct 19
MDE
José María Córdova Intl.
PTY
Tocumen Intl.
$330 Roundtrip, found 1 day ago
$330
Roundtrip
found 1 day ago
Select Copa flight, departing Wed, Oct 16 from José María Córdova Intl. to Tocumen Intl., returning Sat, Oct 19, priced at $330 found 1 day ago
Copa
Thu, Oct 17 - Mon, Oct 21
MDE
José María Córdova Intl.
PTY
Tocumen Intl.
$343 Roundtrip, found 1 day ago
$343
Roundtrip
found 1 day ago
Select Copa flight, departing Thu, Oct 17 from José María Córdova Intl. to Tocumen Intl., returning Mon, Oct 21, priced at $343 found 1 day ago
Copa
Sat, Oct 19 - Sat, Oct 19
MDE
José María Córdova Intl.
PTY
Tocumen Intl.
$357 Roundtrip, found 1 day ago
$357
Roundtrip
found 1 day ago
Select Copa flight, departing Sat, Oct 19 from José María Córdova Intl. to Tocumen Intl., returning Sat, Oct 19, priced at $357 found 1 day ago
Copa
Wed, Oct 16 - Fri, Oct 18
MDE
José María Córdova Intl.
PTY
Tocumen Intl.
$366 Roundtrip, found 1 day ago
$366
Roundtrip
found 1 day ago
Select Copa flight, departing Wed, Oct 16 from José María Córdova Intl. to Tocumen Intl., returning Fri, Oct 18, priced at $366 found 1 day ago
Delta
Fri, Dec 6 - Tue, Dec 10
CHS
Charleston Intl.
PTY
Tocumen Intl.
$382 Roundtrip, found 8 hours ago
$382
Roundtrip
found 8 hours ago
Select Delta flight, departing Fri, Dec 6 from Charleston Intl. to Tocumen Intl., returning Tue, Dec 10, priced at $382 found 8 hours ago
American Airlines
Fri, Dec 6 - Mon, Dec 9
CHS
Charleston Intl.
PTY
Tocumen Intl.
$387 Roundtrip, found 8 hours ago
$387
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Fri, Dec 6 from Charleston Intl. to Tocumen Intl., returning Mon, Dec 9, priced at $387 found 8 hours ago
Delta
Mon, Oct 14 - Tue, Oct 29
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$402 Roundtrip, found 3 days ago
$402
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Oct 14 from Hartsfield-Jackson Atlanta Intl. to Tocumen Intl., returning Tue, Oct 29, priced at $402 found 3 days ago
United
Sat, Oct 12 - Fri, Oct 18
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$417 Roundtrip, just found
$417
Roundtrip
just found
Select United flight, departing Sat, Oct 12 from Hartsfield-Jackson Atlanta Intl. to Tocumen Intl., returning Fri, Oct 18, priced at $417 just found
avianca
Thu, Oct 17 - Mon, Oct 21
MDE
José María Córdova Intl.
PTY
Tocumen Intl.
$426 Roundtrip, found 1 day ago
$426
Roundtrip
found 1 day ago
Select avianca flight, departing Thu, Oct 17 from José María Córdova Intl. to Tocumen Intl., returning Mon, Oct 21, priced at $426 found 1 day ago
Copa
Thu, Oct 31 - Tue, Nov 5
MCO
Orlando Intl.
PTY
Tocumen Intl.
$448 Roundtrip, found 2 days ago
$448
Roundtrip
found 2 days ago
Select Copa flight, departing Thu, Oct 31 from Orlando Intl. to Tocumen Intl., returning Tue, Nov 5, priced at $448 found 2 days ago
Delta
Mon, Jun 30 - Thu, Aug 14
SAT
San Antonio Intl.
PTY
Tocumen Intl.
$448 Roundtrip, found 6 days ago
$448
Roundtrip
found 6 days ago
Select Delta flight, departing Mon, Jun 30 from San Antonio Intl. to Tocumen Intl., returning Thu, Aug 14, priced at $448 found 6 days ago
Delta
Mon, Nov 11 - Mon, Nov 18
AUS
Austin-Bergstrom Intl.
PTY
Tocumen Intl.
$454 Roundtrip, just found
$454
Roundtrip
just found
Select Delta flight, departing Mon, Nov 11 from Austin-Bergstrom Intl. to Tocumen Intl., returning Mon, Nov 18, priced at $454 just found
United
Tue, Oct 29 - Tue, Nov 5
EWR
Newark Liberty Intl. Airport
PTY
Tocumen Intl.
$474 Roundtrip, found 15 hours ago
$474
Roundtrip
found 15 hours ago
Select United flight, departing Tue, Oct 29 from Newark Liberty Intl. Airport to Tocumen Intl., returning Tue, Nov 5, priced at $474 found 15 hours ago
Copa
Tue, Jan 14 - Sat, Jan 18
MBJ
Sir Donald Sangster Intl.
PTY
Tocumen Intl.
$495 Roundtrip, found 9 hours ago
$495
Roundtrip
found 9 hours ago
Select Copa flight, departing Tue, Jan 14 from Sir Donald Sangster Intl. to Tocumen Intl., returning Sat, Jan 18, priced at $495 found 9 hours ago
Delta
Mon, Oct 14 - Thu, Oct 17
OKC
Will Rogers World
PTY
Tocumen Intl.
$573 Roundtrip, found 13 hours ago
$573
Roundtrip
found 13 hours ago
Select Delta flight, departing Mon, Oct 14 from Will Rogers World to Tocumen Intl., returning Thu, Oct 17, priced at $573 found 13 hours ago
Copa
Mon, Nov 25 - Wed, Dec 4
SFO
San Francisco Intl.
PTY
Tocumen Intl.
$675 Roundtrip, found 23 hours ago
$675
Roundtrip
found 23 hours ago
Select Copa flight, departing Mon, Nov 25 from San Francisco Intl. to Tocumen Intl., returning Wed, Dec 4, priced at $675 found 23 hours ago

Cheap Flights to Santa Isabel

Fall in love at first flight with your vacation to Santa Isabel by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Isabel on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Isabel, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Isabel

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Isabel with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the PAC airport.

What is the cheapest month to fly to Santa Isabel?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Isabel are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Isabel?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Isabel.

What airport is best to fly into Santa Isabel?

When you’re planning your trip to Santa Isabel, convenience is the name of the game. Luckily, Santa Isabel Tocumen Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santa Isabel must-do list.

How much are flights to Santa Isabel?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Isabel on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $330, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Isabel?

The trick to saving a stack of cash on your flight to Santa Isabel? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $330 right now, why wait?

Santa Isabel Flight Information
Destination airport
Tocumen Intl.
Destination airport IATA code
PTY
Roundtrip price
$330

Last Minute Hotel Deals in Santa Isabel

San Blas Paradise Private Cabins on Shipwreck Island - meals included
San Blas Paradise Private Cabins on Shipwreck Island - meals included
2 out of 5
Perro Island, Narganá, Guna Yala
The price is $196 per night from Oct 5 to Oct 6
$196
includes taxes & fees
Oct 5 - Oct 6
Book a stay at this beach hotel in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attraction Museum of the ...
San Blas Paradise Private Cabins on Shipwreck Island - meals included
Private Over the Water Cabin on San Blas Island
Private Over the Water Cabin on San Blas Island
2 out of 5
9.542876, -78.899058, Narganá, San Blas
Book a stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Museum of ...
6.4/10 (5 reviews)
"Communication was good and highly organized. We felt safe and didn’t need to lock up our bags or valuables at all times. Weather was rough (not their fault) so the stay was a challenge with super high winds and rain. The island was covered in trash nearly all the way around. Our cabin doors were ..."

Reviewed on Feb 16, 2022

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Private Over the Water Cabin on San Blas Island
Paradise Over the Water Cabins in San Blas
Paradise Over the Water Cabins in San Blas
2.5 out of 5
G4V2 48, Narganá, Guna Yala
Book a stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Porvenir Museum ...
6/10 (1 review)
"29/22 i stay with my family for three nights and 4 days the beds are not comfortable and the fan doesn't work the bathroom need cleaning, the worst part is the sandflyies we got bitten all over our bodies, the owners can do better with proper new nets and fan and maybe spray the place, after the ..."

Reviewed on Sep 4, 2022

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Paradise Over the Water Cabins in San Blas
Private Ocean-Front Cabin with private bathroom on San Blas Island
Private Ocean-Front Cabin with private bathroom on San Blas Island
2 out of 5
Diablo Island, Narganá, Guna Yala
The price is $230 per night from Oct 5 to Oct 6
$230
includes taxes & fees
Oct 5 - Oct 6
Stay at this hotel in San Blas Islands. Enjoy free breakfast, an airport shuttle (surcharge), and a garden. Popular attraction Museum of the Kuna Nation is located ...
Private Ocean-Front Cabin with private bathroom on San Blas Island
Private wood Cabins on San Blas island - private bathroom
Private wood Cabins on San Blas island - private bathroom
2 out of 5
Wailidup Island, Narganá, Guna Yala
Stay at this hotel in San Blas Islands. Enjoy free breakfast, a beach locale, and a marina. Popular attractions Museum of the Kuna Nation and Porvenir Museum ...
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Private wood Cabins on San Blas island - private bathroom
Cabins on paradise San Blas island
Cabins on paradise San Blas island
2 out of 5
9.587566, -78.879820, Narganá, San Blas
The price is $329 per night from Oct 5 to Oct 6
$329
includes taxes & fees
Oct 5 - Oct 6
Stay at this hotel in Narganá. Enjoy free breakfast, an airport shuttle (surcharge), and a snack bar/deli. Popular attraction Museum is located nearby.
Cabins on paradise San Blas island
The Jungle Lodge at Kalu Yala - Glamping
The Jungle Lodge at Kalu Yala - Glamping
2 out of 5
7P47 2M Cerro Azul, San Martín, Panama
Book a stay at this family-friendly campground in San Martín. Enjoy free WiFi, free parking, and 5 outdoor pools. Popular attractions Honeycreeper Ridge Trail ...
2/10 (1 review)
Rats and Mangey dogs
"The place is dirty and falling apart. The food is similar to that served in an elementary cafeteria. I was placed in a Teepee where the linens were dirty and wet towels were on the footstool. I was told to put my things there, and they would send someone to clean it. That never happened, so I moved ..."

Reviewed on Jul 27, 2022

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The Jungle Lodge at Kalu Yala - Glamping
Hotel El Porvenir
Hotel El Porvenir
2 out of 5
Isla Porvenir, Narganá, Guna Yala
Stay at this hotel in San Blas Islands. Enjoy free breakfast, a beach locale, and a bar/lounge. Popular attractions Porvenir Museum and Museum are located ...
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Hotel El Porvenir
See all 46 properties in Santa Isabel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.