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Santa Isabel

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Santa Isabel Flights as Low as $307

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Fri, Dec 6 - Mon, Dec 9
MIA
Miami Intl.
PTY
Tocumen Intl.
$307 Roundtrip, found 3 days ago
$307
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Dec 6 from Miami Intl. to Tocumen Intl., returning Mon, Dec 9, priced at $307 found 3 days ago
Copa
Fri, Dec 6 - Mon, Dec 9
MIA
Miami Intl.
PTY
Tocumen Intl.
$345 Roundtrip, found 3 days ago
$345
Roundtrip
found 3 days ago
Select Copa flight, departing Fri, Dec 6 from Miami Intl. to Tocumen Intl., returning Mon, Dec 9, priced at $345 found 3 days ago
American Airlines
Fri, Dec 6 - Mon, Dec 9
MIA
Miami Intl.
PTY
Tocumen Intl.
$352 Roundtrip, found 3 days ago
$352
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Dec 6 from Miami Intl. to Tocumen Intl., returning Mon, Dec 9, priced at $352 found 3 days ago
Copa
Wed, Jan 1 - Tue, Jan 14
MIA
Miami Intl.
PTY
Tocumen Intl.
$355 Roundtrip, found 4 days ago
$355
Roundtrip
found 4 days ago
Select Copa flight, departing Wed, Jan 1 from Miami Intl. to Tocumen Intl., returning Tue, Jan 14, priced at $355 found 4 days ago
American Airlines
Sat, Jan 11 - Wed, Jan 15
MIA
Miami Intl.
PTY
Tocumen Intl.
$441 Roundtrip, found 12 hours ago
$441
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sat, Jan 11 from Miami Intl. to Tocumen Intl., returning Wed, Jan 15, priced at $441 found 12 hours ago
Delta
Thu, May 1 - Sat, May 10
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$491 Roundtrip, found 3 days ago
$491
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, May 1 from Hartsfield-Jackson Atlanta Intl. to Tocumen Intl., returning Sat, May 10, priced at $491 found 3 days ago
Delta
Mon, Apr 28 - Sun, May 4
TPA
Tampa Intl.
PTY
Tocumen Intl.
$502 Roundtrip, found 6 days ago
$502
Roundtrip
found 6 days ago
Select Delta flight, departing Mon, Apr 28 from Tampa Intl. to Tocumen Intl., returning Sun, May 4, priced at $502 found 6 days ago
American Airlines
Mon, Feb 3 - Thu, Feb 20
PNS
Pensacola Intl.
PTY
Tocumen Intl.
$516 Roundtrip, found 11 hours ago
$516
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Mon, Feb 3 from Pensacola Intl. to Tocumen Intl., returning Thu, Feb 20, priced at $516 found 11 hours ago
United
Wed, Feb 5 - Wed, Feb 12
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$516 Roundtrip, found 4 days ago
$516
Roundtrip
found 4 days ago
Select United flight, departing Wed, Feb 5 from Hartsfield-Jackson Atlanta Intl. to Tocumen Intl., returning Wed, Feb 12, priced at $516 found 4 days ago
Copa
Sat, Nov 30 - Thu, Dec 5
MBJ
Sir Donald Sangster Intl.
PTY
Tocumen Intl.
$519 Roundtrip, found 11 hours ago
$519
Roundtrip
found 11 hours ago
Select Copa flight, departing Sat, Nov 30 from Sir Donald Sangster Intl. to Tocumen Intl., returning Thu, Dec 5, priced at $519 found 11 hours ago
Copa
Wed, Dec 25 - Wed, Jan 1
POS
Piarco Intl.
PTY
Tocumen Intl.
$525 Roundtrip, found 12 hours ago
$525
Roundtrip
found 12 hours ago
Select Copa flight, departing Wed, Dec 25 from Piarco Intl. to Tocumen Intl., returning Wed, Jan 1, priced at $525 found 12 hours ago
avianca
Thu, Jan 9 - Sun, Jan 12
MIA
Miami Intl.
PTY
Tocumen Intl.
$536 Roundtrip, found 12 hours ago
$536
Roundtrip
found 12 hours ago
Select avianca flight, departing Thu, Jan 9 from Miami Intl. to Tocumen Intl., returning Sun, Jan 12, priced at $536 found 12 hours ago
Copa
Tue, Dec 24 - Sun, Dec 29
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$583 Roundtrip, found 1 day ago
$583
Roundtrip
found 1 day ago
Select Copa flight, departing Tue, Dec 24 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Sun, Dec 29, priced at $583 found 1 day ago
Copa
Sun, Dec 29 - Mon, Dec 30
ORD
O'Hare Intl.
PTY
Tocumen Intl.
$624 Roundtrip, found 17 hours ago
$624
Roundtrip
found 17 hours ago
Select Copa flight, departing Sun, Dec 29 from O'Hare Intl. to Tocumen Intl., returning Mon, Dec 30, priced at $624 found 17 hours ago
Delta
Wed, Jan 1 - Wed, Jan 8
CVG
Cincinnati - Northern Kentucky Intl.
PTY
Tocumen Intl.
$731 Roundtrip, found 1 day ago
$731
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Jan 1 from Cincinnati - Northern Kentucky Intl. to Tocumen Intl., returning Wed, Jan 8, priced at $731 found 1 day ago
United
Sun, Feb 2 - Thu, Feb 20
OGG
Kahului
PTY
Tocumen Intl.
$833 Roundtrip, found 1 day ago
$833
Roundtrip
found 1 day ago
Select United flight, departing Sun, Feb 2 from Kahului to Tocumen Intl., returning Thu, Feb 20, priced at $833 found 1 day ago

Cheap Flights to Santa Isabel

Fall in love at first flight with your vacation to Santa Isabel by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Isabel on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Isabel, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Isabel

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Isabel with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the PAC airport.

What is the cheapest month to fly to Santa Isabel?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Isabel are in December, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Isabel?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Isabel.

What airport is best to fly into Santa Isabel?

When you’re planning your trip to Santa Isabel, convenience is the name of the game. Luckily, Santa Isabel Tocumen Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santa Isabel must-do list.

How much are flights to Santa Isabel?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Isabel on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $307, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Isabel?

The trick to saving a stack of cash on your flight to Santa Isabel? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $307 right now, why wait?

Santa Isabel Flight Information
Destination airport
Tocumen Intl.
Destination airport IATA code
PTY
Roundtrip price
$307

Last Minute Hotel Deals in Santa Isabel

Private Ocean-Front Cabin with private bathroom on San Blas Island
Private Ocean-Front Cabin with private bathroom on San Blas Island
2 out of 5
Diablo Island, Narganá, Guna Yala
The price is $230 per night from Nov 28 to Nov 29
$230
includes taxes & fees
Nov 28 - Nov 29
Stay at this hotel in San Blas Islands. Enjoy free breakfast, an airport shuttle (surcharge), and a garden. Popular attraction Museum of the Kuna Nation is located ...
Private Ocean-Front Cabin with private bathroom on San Blas Island
San Blas Paradise Private Cabins on Shipwreck Island - meals included
San Blas Paradise Private Cabins on Shipwreck Island - meals included
2 out of 5
Perro Island, Narganá, Guna Yala
The price is $196 per night from Nov 28 to Nov 29
$196
includes taxes & fees
Nov 28 - Nov 29
Book a stay at this beach hotel in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attraction Museum of the ...
San Blas Paradise Private Cabins on Shipwreck Island - meals included
Private Over the Water Cabin on San Blas Island
Private Over the Water Cabin on San Blas Island
2 out of 5
9.542876, -78.899058, Narganá, San Blas
Book a stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Museum of ...
6.4/10 (5 reviews)
"Communication was good and highly organized. We felt safe and didn’t need to lock up our bags or valuables at all times. Weather was rough (not their fault) so the stay was a challenge with super high winds and rain. The island was covered in trash nearly all the way around. Our cabin doors were ..."

Reviewed on Feb 16, 2022

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Private Over the Water Cabin on San Blas Island
Paradise Over the Water Cabins in San Blas
Paradise Over the Water Cabins in San Blas
2.5 out of 5
G4V2 48, Narganá, Guna Yala
Book a stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Porvenir Museum ...
6/10 (1 review)
"29/22 i stay with my family for three nights and 4 days the beds are not comfortable and the fan doesn't work the bathroom need cleaning, the worst part is the sandflyies we got bitten all over our bodies, the owners can do better with proper new nets and fan and maybe spray the place, after the ..."

Reviewed on Sep 4, 2022

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Paradise Over the Water Cabins in San Blas
Private wood Cabins on San Blas island - private bathroom
Private wood Cabins on San Blas island - private bathroom
2 out of 5
Wailidup Island, Narganá, Guna Yala
Stay at this hotel in San Blas Islands. Enjoy free breakfast, a beach locale, and a marina. Popular attractions Museum of the Kuna Nation and Porvenir Museum ...
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Private wood Cabins on San Blas island - private bathroom
Cabins on paradise San Blas island
Cabins on paradise San Blas island
2 out of 5
9.587566, -78.879820, Narganá, San Blas
Stay at this hotel in Narganá. Enjoy free breakfast, an airport shuttle (surcharge), and a snack bar/deli. Popular attraction Museum is located nearby.
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Cabins on paradise San Blas island
The Jungle Lodge at Kalu Yala - Glamping
The Jungle Lodge at Kalu Yala - Glamping
2 out of 5
7P47 2M Cerro Azul, San Martín, Panama
Book a stay at this family-friendly campground in San Martín. Enjoy free WiFi, free parking, and 5 outdoor pools. Popular attractions Honeycreeper Ridge Trail ...
2/10 (1 review)
Rats and Mangey dogs
"The place is dirty and falling apart. The food is similar to that served in an elementary cafeteria. I was placed in a Teepee where the linens were dirty and wet towels were on the footstool. I was told to put my things there, and they would send someone to clean it. That never happened, so I moved ..."

Reviewed on Jul 27, 2022

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The Jungle Lodge at Kalu Yala - Glamping
Hotel El Porvenir
Hotel El Porvenir
2 out of 5
Isla Porvenir, Narganá, Guna Yala
Stay at this hotel in San Blas Islands. Enjoy free breakfast, a beach locale, and a bar/lounge. Popular attractions Porvenir Museum and Museum are located ...
Get rates
Hotel El Porvenir
See all 47 properties in Santa Isabel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.