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Santa Isabel Vacation Packages

Build your package with 2 more options

Santa Isabel Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.
The Sands by Wynwood House

The Sands by Wynwood House

3 out of 5
Price was $595, price is now $465 per person
$465
per person
May 7 - May 11
found 1 hour ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, rainfall showerheads, and an outdoor pool. Popular attractions Cinta Costera and Albrook Shopping Mall are located nearby.
Mahogany Suites

Mahogany Suites

2 out of 5
Price was $783, price is now $502 per person
$502
per person
May 14 - May 17
found 9 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this golf hotel in Arraijan. Enjoy free WiFi, a golf course, and a garden. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Save 100% on your flight
Price was $2,334, price is now $1,546 per person
$1,546
per person
Apr 29 - May 6
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Cinta Costera and Amador Causeway are located nearby.
Hotel Plaza Herrera

Hotel Plaza Herrera

4 out of 5
Price was $1,106, price is now $763 per person
$763
per person
May 14 - May 17
found 9 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, an attached winery, and 2 bars/lounges. Popular attractions Cinta Costera and Amador Causeway are located nearby.
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Price was $870, price is now $609 per person
$609
per person
Jun 23 - Jun 27
found 5 hours ago
Roundtrip non-stop flight included
Miami (MIA) to Panama City (PTY)
Book a stay at this golf B&B in Rio Hato. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Playa Blanca and Santa Clara Beach are located nearby.
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Price was $1,331, price is now $986 per person
$986
per person
Jun 4 - Jun 8
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Avenida Balboa and Via Espana are located nearby.
W Panama

W Panama

5 out of 5
Price was $1,260, price is now $943 per person
$943
per person
Apr 30 - May 5
found 13 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy 2 restaurants, 3 hot tubs, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions Via Espana and Avenida Balboa are located nearby.

Santa Isabel Vacation Packages 3-4 Night Stays

Price found within the past 48 hours. Click for updated prices.
Mahogany Suites

Mahogany Suites

2 out of 5
Price was $783, price is now $502 per person
$502
per person
May 14 - May 17
found 9 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Hotel Plaza Herrera

Hotel Plaza Herrera

4 out of 5
Casco Viejo
Price was $1,106, price is now $763 per person
$763
per person
May 14 - May 17
found 9 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Price was $870, price is now $609 per person
$609
per person
Jun 23 - Jun 27
found 5 hours ago
Roundtrip non-stop flight included
Miami (MIA) to Panama City (PTY)

Santa Isabel Vacation Packages 5-7 Night Stays

Price found within the past 48 hours. Click for updated prices.
Mahogany Suites

Mahogany Suites

2 out of 5
Price was $1,434, price is now $758 per person
$758
per person
May 30 - Jun 6
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $2,316, price is now $1,407 per person
$1,407
per person
Jun 18 - Jun 25
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Price was $1,182, price is now $868 per person
$868
per person
May 3 - May 8
found 1 hour ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Copa
Tue, Jun 30 - Thu, Jul 9
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$275 Roundtrip, found 1 hour ago
$275
Roundtrip
found 1 hour ago
Select Copa flight, departing Tue, Jun 30 from Juan Santamaría Intl. to Tocumen Intl., returning Thu, Jul 9, priced at $275 found 1 hour ago
Copa
Wed, May 13 - Wed, May 20
MIA
Miami Intl.
PTY
Tocumen Intl.
$285 Roundtrip, just found
$285
Roundtrip
just found
Select Copa flight, departing Wed, May 13 from Miami Intl. to Tocumen Intl., returning Wed, May 20, priced at $285 just found
United
Sat, May 16 - Wed, May 20
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$370 Roundtrip, found 2 days ago
$370
Roundtrip
found 2 days ago
Select United flight, departing Sat, May 16 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Wed, May 20, priced at $370 found 2 days ago
avianca
Sat, Oct 31 - Sun, Nov 15
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$398 Roundtrip, just found
$398
Roundtrip
just found
Select avianca flight, departing Sat, Oct 31 from John F. Kennedy Intl. to Tocumen Intl., returning Sun, Nov 15, priced at $398 just found