Search Deals onSanta Isabel Vacation Packages
Santa Isabel Flight + Hotel Packages
Price found within the past 48 hours. Click for updated prices.
Casa Mallet by Wynwood House
Price was $1,199, price is now $888 per person
$888
per person
Oct 19 - Oct 23
found 3 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, parking (surcharge), and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Nice apartment ! Clean and great location
Reviewed on Aug 13, 2026
Central Hotel Panama Casco Viejo
Price was $2,083, price is now $952 per person
$952
per person
Nov 14 - Nov 19
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Don’t expect to sleep
Upon checkin I was out in my “Jr Suite”. It was just a room. But worse, I tried to soon and heard a rhythmic banging that was impossible to sleep through. It was so bad that I decided to see what it was. My room was DIRECTLY UNDER the gym, in a centuries old building?! If anyone is on the treadmill- you’re screwed! Anyone dropping weights, anything. Walls were paper thin. Outside of that… the place was beautiful, and fantastic location!
Reviewed on Aug 29, 2026
Megapolis Hotel Panamá
Save 100% on your flight
Price was $2,455, price is now $1,171 per person
$1,171
per person
Oct 6 - Oct 13
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
El agua caliente no funcionaba me cambiaron de habitación y no funcionaba el control del
TV y no hubo quien lo arreglara
Reviewed on Aug 28, 2026
Decapolis Hotel Panama City
Price was $1,517, price is now $950 per person
$950
per person
Oct 6 - Oct 13
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
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Reviewed on Aug 29, 2026
Hotel Riu Plaza Panama
Price was $1,475, price is now $974 per person
$974
per person
Oct 6 - Oct 13
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
The breakfast was excellent and the staff was great. All in all, the hotel is an A+
Reviewed on Aug 29, 2026
Hyatt Regency Panama City
Price was $1,635, price is now $1,114 per person
$1,114
per person
Oct 6 - Oct 13
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and 2 restaurants. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Great place and great personal, hope to be back some time soon
Reviewed on Aug 28, 2026
Riande Aeropuerto Hotel & Casino
Price was $1,409, price is now $1,032 per person
$1,032
per person
Nov 13 - Nov 19
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.
Sheraton Grand Panama
Price was $1,383, price is now $1,036 per person
$1,036
per person
Oct 6 - Oct 13
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Multiplaza Pacific Mall are located nearby.
Santa Isabel Vacation Packages 3-4 Night Stays
Price found within the past 48 hours. Click for updated prices.
Santa Isabel Vacation Packages 5-7 Night Stays
Price found within the past 48 hours. Click for updated prices.
Top Flight Deals
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
Tue, Oct 20 - Sun, Oct 25
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$264 Roundtrip, found 1 hour ago
$264
Roundtrip
found 1 hour ago
Tue, Oct 27 - Sun, Nov 1
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$398 Roundtrip, found 1 day ago
$398
Roundtrip
found 1 day ago
Sat, Oct 31 - Mon, Nov 9
MIA
Miami Intl.
PTY
Tocumen Intl.
$475 Roundtrip, found 13 hours ago
$475
Roundtrip
found 13 hours ago
Thu, Dec 31 - Wed, Jan 13
LAX
Los Angeles Intl.
PTY
Tocumen Intl.
$539 Roundtrip, found 1 hour ago
$539
Roundtrip
found 1 hour ago
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