Search Deals onSanta Isabel Vacation Packages
Santa Isabel Flight + Hotel Packages
Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino
Price was $1,017, price is now $780 per person
$780
per person
Oct 2 - Oct 5
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.
Muy bonito y muy comds la habitación
Reviewed on Aug 6, 2026
Megapolis Hotel Panamá
Save 100% on your flight
Price was $1,676, price is now $965 per person
$965
per person
Oct 9 - Oct 13
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Central Hotel Panama Casco Viejo
Price was $1,376, price is now $807 per person
$807
per person
Oct 1 - Oct 4
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
El hotel está perfectamente ubicado. El edificio está impecable.
Reviewed on Aug 7, 2026
Hotel Riu Plaza Panama
Price was $1,132, price is now $843 per person
$843
per person
Oct 9 - Oct 13
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Hyatt Regency Panama City
Price was $1,194, price is now $905 per person
$905
per person
Oct 9 - Oct 13
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and 2 restaurants. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Great atmosphere. Staff was very helpful when asking for directions and information, some more than others.
Everything was clean. I really liked this hotel and my stay.
Reviewed on Aug 4, 2026
Villa Marina Hotel
Price was $1,038, price is now $800 per person
$800
per person
Oct 11 - Oct 16
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Book a stay at this beach hotel in Las Escobas del Venado. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the helpful staff in our reviews. Popular attraction Venao Beach is located nearby.
We stayed at the Condos, very clean, spacious, well mantained, comfortable. A little too far from the main hotel and restaurant, i recommend to have a car if staying there.
Staff VERY nice and helpful.
Reviewed on Aug 3, 2026
Casa Mallet by Wynwood House
Price was $1,651, price is now $1,289 per person
$1,289
per person
Oct 8 - Oct 13
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, parking (surcharge), and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Well appointed, friendly staff on site and excellent location. Noise from the outside does get in but it didnt bother us too much. Would definitely stay again!
Reviewed on Jul 28, 2026
Las Clementinas
Price was $1,096, price is now $870 per person
$870
per person
Oct 1 - Oct 4
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this aparthotel in Panama City. Enjoy free WiFi, parking (surcharge), and an airport shuttle (surcharge). Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Very comfortable bed, cold air conditioning. The area felt very safe, being right across the street from the police station. Walkable to everything.
Reviewed on Aug 7, 2026
Santa Isabel Vacation Packages 3-4 Night Stays
Price found within the past 48 hours. Click for updated prices.
Santa Isabel Vacation Packages 5-7 Night Stays
Price found within the past 48 hours. Click for updated prices.
Top Flight Deals
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
Tue, Oct 20 - Sun, Oct 25
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$243 Roundtrip, found 2 hours ago
$243
Roundtrip
found 2 hours ago
Sat, Oct 3 - Tue, Oct 6
MIA
Miami Intl.
PTY
Tocumen Intl.
$416 Roundtrip, found 3 hours ago
$416
Roundtrip
found 3 hours ago
Sat, Oct 3 - Tue, Oct 6
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$496 Roundtrip, found 21 hours ago
$496
Roundtrip
found 21 hours ago
Mon, Nov 16 - Mon, Nov 23
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$590 Roundtrip, found 5 days ago
$590
Roundtrip
found 5 days ago
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