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Hotels in Santa Isabel

Choose from 48 Santa Isabel Hotel Deals

Private Ocean-Front Cabin with private bathroom on San Blas Island
Private Ocean-Front Cabin with private bathroom on San Blas Island
2 out of 5
Diablo Island, Narganá, Guna Yala
  • 2 hours drive from Chagres National Park
The price is $230 per night from Dec 26 to Dec 27
$230
includes taxes & fees
Dec 26 - Dec 27
Stay at this hotel in San Blas Islands. Enjoy free breakfast, an airport shuttle (surcharge), and a garden. Popular attraction Museum of the Kuna Nation is located ...
Private Ocean-Front Cabin with private bathroom on San Blas Island
 San Blas Paradise Private Cabins on Shipwreck Island - meals included
San Blas Paradise Private Cabins on Shipwreck Island - meals included
2 out of 5
Perro Island, Narganá, Guna Yala
  • 2 hours drive from Chagres National Park
The price is $248 per night from Jan 4 to Jan 5
$248
includes taxes & fees
Jan 4 - Jan 5, 2025
Book a stay at this beach hotel in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attraction Museum of the ...
San Blas Paradise Private Cabins on Shipwreck Island - meals included
Private Over the Water Cabin on San Blas Island
Private Over the Water Cabin on San Blas Island
2 out of 5
9.542876, -78.899058, Narganá, San Blas
  • 2 hours drive from Chagres National Park
Book a stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Museum of ...
6.4/10 (5 reviews)
"Communication was good and highly organized. We felt safe and didn’t need to lock up our bags or valuables at all times. Weather was rough (not their fault) so the stay was a challenge with super high winds and rain. The island was covered in trash nearly all the way around. Our cabin doors were ..."

Reviewed on Feb 16, 2022

Private Over the Water Cabin on San Blas Island
Cabins in Asserya Island - San Blas paradise - meals included
Cabins in Asserya Island - San Blas paradise - meals included
2 out of 5
Aroma Island (Isla Anzuelo), Narganá, Guna Yala
  • 1 hour drive from Chagres National Park
The price is $153 per night from Jan 6 to Jan 7
$153
includes taxes & fees
Jan 6 - Jan 7, 2025
Stay at this hotel in San Blas Islands. Enjoy free breakfast, a marina, and an airport shuttle (surcharge). Popular attractions Museum and Porvenir Museum are ...
Cabins in Asserya Island - San Blas paradise - meals included
 Paradise Over the Water Cabins in San Blas
Paradise Over the Water Cabins in San Blas
2.5 out of 5
G4V2 48, Narganá, Guna Yala
  • 1 hour drive from Chagres National Park
Book a stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Porvenir Museum ...
6/10 (1 review)
"29/22 i stay with my family for three nights and 4 days the beds are not comfortable and the fan doesn't work the bathroom need cleaning, the worst part is the sandflyies we got bitten all over our bodies, the owners can do better with proper new nets and fan and maybe spray the place, after the ..."

Reviewed on Sep 4, 2022

Paradise Over the Water Cabins in San Blas
Private wood Cabins on San Blas island - private bathroom
Private wood Cabins on San Blas island - private bathroom
2 out of 5
Wailidup Island, Narganá, Guna Yala
  • 2 hours drive from Chagres National Park
Stay at this hotel in San Blas Islands. Enjoy free breakfast, a beach locale, and a marina. Popular attractions Museum of the Kuna Nation and Porvenir Museum ...
Private wood Cabins on San Blas island - private bathroom
Cabins on paradise San Blas island
Cabins on paradise San Blas island
2 out of 5
9.587566, -78.879820, Narganá, San Blas
  • 1 hour drive from Chagres National Park
Stay at this hotel in Narganá. Enjoy free breakfast, an airport shuttle (surcharge), and a snack bar/deli. Popular attraction Museum is located nearby.
Cabins on paradise San Blas island
The Jungle Lodge at Kalu Yala - Glamping
The Jungle Lodge at Kalu Yala - Glamping
2 out of 5
7P47 2M Cerro Azul, San Martín, Panama
  • 37 min drive from Chagres National Park
Book a stay at this family-friendly campground in San Martín. Enjoy free WiFi, free parking, and 5 outdoor pools. Popular attractions Honeycreeper Ridge Trail ...
2/10 (1 review)
Rats and Mangey dogs
"The place is dirty and falling apart. The food is similar to that served in an elementary cafeteria. I was placed in a Teepee where the linens were dirty and wet towels were on the footstool. I was told to put my things there, and they would send someone to clean it. That never happened, so I moved ..."

Reviewed on Jul 27, 2022

The Jungle Lodge at Kalu Yala - Glamping
Hotel El Porvenir
Hotel El Porvenir
2 out of 5
Isla Porvenir, Narganá, Guna Yala
  • 1 hour drive from Chagres National Park
Stay at this hotel in San Blas Islands. Enjoy free breakfast, a beach locale, and a bar/lounge. Popular attractions Porvenir Museum and Museum are located ...
Hotel El Porvenir
BURBAYAR ECO LODGE
BURBAYAR ECO LODGE
3 out of 5
Vía a Nasugandí, KM 14, El Llano, Panama Province
  • 1 hour drive from Chagres National Park
Stay at this 3-star farm stay in El Llano. Enjoy free parking, breakfast (surcharge), and a garden.
8/10 Very Good! (1 review)
"Hotel rústico en medio de la montaña. Muy limpio. Excelente atención de parte de Mirna y Antonio. Comida sencilla pero muy sabrosa. Un lugar para desconectarse de la ciudad. Aspectos a mejorar: la presión de agua en la ducha es muy baja. No había jabón en los baños. Actualmente están arreglando la ..."

Reviewed on May 15, 2023

BURBAYAR ECO LODGE
The Camp at Kalu Yala
The Camp at Kalu Yala
2 out of 5
San Martín, San Martín, Panama Province
  • 31 min drive from Chagres National Park
Book a stay at this family-friendly campground in San Martín. Enjoy free parking, 10 outdoor pools, and breakfast (surcharge). Popular attraction Honeycreeper ...
The Camp at Kalu Yala
Cabañas Isla Nubesidub San Blas
Cabañas Isla Nubesidub San Blas
2 out of 5
Isla Nubesidub San Blas, Narganá, San Blas Guna Yala
  • 1 hour drive from Chagres National Park
Book a stay at this beach lodge in San Blas Islands. Enjoy a beach locale, breakfast (surcharge), and an airport shuttle (surcharge). Popular attractions Porvenir ...
Cabañas Isla Nubesidub San Blas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Santa Isabel

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Santa Isabel.

Choosing the right hotel in Colón has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Santa Isabel’s 48 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $153. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Santa Isabel hotel deals at the last minute.

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Frequently Asked Questions About Santa Isabel hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Santa Isabel?

With over 48 hotels in Santa Isabel, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $153.

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