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Southeast Illinois

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Cheap Flights to Southeast Illinois

Fall in love at first flight with your vacation to Southeast Illinois by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southeast Illinois on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Southeast Illinois, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Southeast Illinois

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southeast Illinois with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MDH airport.

What is the cheapest month to fly to Southeast Illinois?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southeast Illinois are in , but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Southeast Illinois?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find  to choose from for your flight to Southeast Illinois.

What airport is best to fly into Southeast Illinois?

When you’re planning your trip to Southeast Illinois, convenience is the name of the game. Luckily, Southeast Illinois Evansville Regional Airport is nearby so you can deplane and get going on checking off everything on your Southeast Illinois must-do list.

How much are flights to Southeast Illinois?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southeast Illinois on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as , you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Southeast Illinois?

The trick to saving a stack of cash on your flight to Southeast Illinois? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as  right now, why wait?

Southeast Illinois Flight Information
Destination airport
Southeast Illinois
Destination airport IATA code
MDH

Last Minute Hotel Deals in Southeast Illinois

Best Western Delta Inn

Best Western Delta Inn

2.5 out of 5
1509 Hampton Dr, Located right off of I-57/70, Effingham, IL
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,009 reviews)
Clean room, friendly staff, comfortable bed, but the WORST bed pillows ever!! For a king size bed there were 4 small pillows, about the size of a couch throw pillow. They were way too soft, no support at all.

Reviewed on Oct 29, 2025

Best Western Delta Inn
Unique Suites Hotel

Unique Suites Hotel

2.5 out of 5
920 W Lincoln Ave, Charleston, IL
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (697 reviews)
Check in was a little strange but otherwise a good stay

Reviewed on Oct 12, 2025

Unique Suites Hotel
Holiday Inn Express Metropolis by IHG

Holiday Inn Express Metropolis by IHG

2.5 out of 5
2179 East 5th Street, Metropolis, IL
Book a stay at this business-friendly hotel in Metropolis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,002 reviews)
Good checkin staff

Reviewed on Nov 2, 2025

Holiday Inn Express Metropolis by IHG
Comfort Suites Mattoon East

Comfort Suites Mattoon East

2.5 out of 5
1408 Broadway Ave E, Mattoon, IL
Book a stay at this business-friendly hotel in Mattoon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (849 reviews)
Easy check in, great price, room is clean but, there’s an odor that smells like sweaty clothes(?)

Reviewed on Oct 30, 2025

Comfort Suites Mattoon East
La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham

3 out of 5
1103 Avenue Of Mid America, Effingham, IL
Stay at this 3-star business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,005 reviews)
Yes

Reviewed on Oct 30, 2025

La Quinta Inn & Suites by Wyndham Effingham
Days Inn & Suites by Wyndham Casey

Days Inn & Suites by Wyndham Casey

2 out of 5
933 N Route 49, Casey, IL
Book a stay at this business-friendly hotel in Casey. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.4/10 Good! (810 reviews)
Room was clean and it was quiet

Reviewed on Oct 28, 2025

Days Inn & Suites by Wyndham Casey
Hampton Inn & Suites Effingham

Hampton Inn & Suites Effingham

2.5 out of 5
1305 N Keller Dr, Effingham, IL
Stay at this hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
9.4/10 Exceptional! (652 reviews)
Great Experience

Reviewed on Oct 24, 2025

Hampton Inn & Suites Effingham
Super 8 by Wyndham Grayville

Super 8 by Wyndham Grayville

2 out of 5
2060 County Road 2450 N, I-64, Exit 130 (hwy.1), Grayville, IL
Book a stay at this business-friendly motel in Grayville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (472 reviews)
Not bad for the price. The only downside is it’s a small town not many food options. The staff was polite and the coffee was pretty good every morning. Very consistent parking lot had a lot of cigarette butts on the floor every night but overall a good experience there could be a little bit more ...

Reviewed on Oct 18, 2025

Super 8 by Wyndham Grayville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.