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Southeast Illinois

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Southeast Illinois Flights as Low as $604

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Wed, Jan 22 - Tue, Jan 28
ORD
O'Hare Intl.
PAH
Barkley Regional
$604 Roundtrip, found 15 hours ago
$604
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Wed, Jan 22 from O'Hare Intl. to Barkley Regional, returning Tue, Jan 28, priced at $604 found 15 hours ago
American Airlines
Wed, Jan 22 - Tue, Jan 28
ORD
O'Hare Intl.
PAH
Barkley Regional
$614 Roundtrip, found 15 hours ago
$614
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Wed, Jan 22 from O'Hare Intl. to Barkley Regional, returning Tue, Jan 28, priced at $614 found 15 hours ago
American Airlines
Wed, Jan 22 - Tue, Jan 28
ORD
O'Hare Intl.
PAH
Barkley Regional
$624 Roundtrip, found 15 hours ago
$624
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Wed, Jan 22 from O'Hare Intl. to Barkley Regional, returning Tue, Jan 28, priced at $624 found 15 hours ago
American Airlines
Wed, Jan 22 - Tue, Jan 28
ORD
O'Hare Intl.
PAH
Barkley Regional
$791 Roundtrip, found 20 hours ago
$791
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Wed, Jan 22 from O'Hare Intl. to Barkley Regional, returning Tue, Jan 28, priced at $791 found 20 hours ago
American Airlines
Wed, Jan 22 - Tue, Jan 28
ORD
O'Hare Intl.
PAH
Barkley Regional
$801 Roundtrip, found 20 hours ago
$801
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Wed, Jan 22 from O'Hare Intl. to Barkley Regional, returning Tue, Jan 28, priced at $801 found 20 hours ago
American Airlines
Wed, Jan 22 - Tue, Jan 28
ORD
O'Hare Intl.
PAH
Barkley Regional
$813 Roundtrip, found 20 hours ago
$813
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Wed, Jan 22 from O'Hare Intl. to Barkley Regional, returning Tue, Jan 28, priced at $813 found 20 hours ago
American Airlines
Wed, Jan 22 - Tue, Jan 28
ORD
O'Hare Intl.
PAH
Barkley Regional
$817 Roundtrip, found 15 hours ago
$817
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Wed, Jan 22 from O'Hare Intl. to Barkley Regional, returning Tue, Jan 28, priced at $817 found 15 hours ago
American Airlines
Wed, Jan 22 - Tue, Jan 28
ORD
O'Hare Intl.
PAH
Barkley Regional
$823 Roundtrip, found 20 hours ago
$823
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Wed, Jan 22 from O'Hare Intl. to Barkley Regional, returning Tue, Jan 28, priced at $823 found 20 hours ago
American Airlines
Wed, Jan 22 - Tue, Jan 28
ORD
O'Hare Intl.
PAH
Barkley Regional
$823 Roundtrip, found 2 days ago
$823
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Jan 22 from O'Hare Intl. to Barkley Regional, returning Tue, Jan 28, priced at $823 found 2 days ago
American Airlines
Wed, Jan 22 - Tue, Jan 28
ORD
O'Hare Intl.
PAH
Barkley Regional
$827 Roundtrip, found 15 hours ago
$827
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Wed, Jan 22 from O'Hare Intl. to Barkley Regional, returning Tue, Jan 28, priced at $827 found 15 hours ago
American Airlines
Wed, Jan 22 - Tue, Jan 28
ORD
O'Hare Intl.
PAH
Barkley Regional
$833 Roundtrip, found 2 days ago
$833
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Jan 22 from O'Hare Intl. to Barkley Regional, returning Tue, Jan 28, priced at $833 found 2 days ago

Cheap Flights to Southeast Illinois

Fall in love at first flight with your vacation to Southeast Illinois by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southeast Illinois on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Southeast Illinois, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Southeast Illinois

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southeast Illinois with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MDH airport.

What is the cheapest month to fly to Southeast Illinois?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southeast Illinois are in January, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Southeast Illinois?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 11 to choose from for your flight to Southeast Illinois.

What airport is best to fly into Southeast Illinois?

When you’re planning your trip to Southeast Illinois, convenience is the name of the game. Luckily, Southeast Illinois Evansville Regional Airport is nearby so you can deplane and get going on checking off everything on your Southeast Illinois must-do list.

How much are flights to Southeast Illinois?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southeast Illinois on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $604, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Southeast Illinois?

The trick to saving a stack of cash on your flight to Southeast Illinois? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $604 right now, why wait?

Southeast Illinois Flight Information
Destination airport
Decatur
Destination airport IATA code
DEC
Roundtrip price
$224

Last Minute Hotel Deals in Southeast Illinois

Best Western Delta Inn
Best Western Delta Inn
2.5 out of 5
1509 Hampton Dr, Located right off of I-57/70, Effingham, IL
The price is $113 per night from Jan 10 to Jan 11
$113
includes taxes & fees
Jan 10 - Jan 11
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,000 reviews)
"The young lady who checked us in was very friendly and efficient."

Reviewed on Dec 30, 2024

Best Western Delta Inn
La Quinta Inn & Suites by Wyndham Effingham
La Quinta Inn & Suites by Wyndham Effingham
2.5 out of 5
1103 Avenue Of Mid America, Effingham, IL
The price is $103 per night from Jan 10 to Jan 11
$103
includes taxes & fees
Jan 10 - Jan 11
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,000 reviews)
"I loved every single thing about it so did my daughters very safe secure and comfortable stay so comfortable even booked another night. I haven’t felt this safe and relaxed in five years."

Reviewed on Jan 5, 2025

La Quinta Inn & Suites by Wyndham Effingham
Baymont by Wyndham Effingham
Baymont by Wyndham Effingham
2.5 out of 5
1811 W Fayette Avenue, I-57 & 70 Exit 159, Effingham, IL
The price is $85 per night from Jan 14 to Jan 15
$85
includes taxes & fees
Jan 14 - Jan 15
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (828 reviews)
"Rooms are well used and definitely freeway noise but so very convenient when we are only looking for a place to grab a nights sleep and not spend a ton"

Reviewed on Jan 2, 2025

Baymont by Wyndham Effingham
Country Inn & Suites by Radisson, Effingham, IL
Country Inn & Suites by Radisson, Effingham, IL
2.5 out of 5
1200 N Raney, Effingham, IL
The price is $108 per night from Jan 10 to Jan 11
$108
includes taxes & fees
Jan 10 - Jan 11
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,000 reviews)
"Nice 'country' Inn :) right by freeway but quiet!"

Reviewed on Jan 2, 2025

Country Inn & Suites by Radisson, Effingham, IL
Unique Suites Hotel
Unique Suites Hotel
2.5 out of 5
920 W Lincoln Ave, Charleston, IL
The price is $102 per night from Jan 8 to Jan 9
$102
includes taxes & fees
Jan 8 - Jan 9
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (608 reviews)
"Great place to stay. Easy to get to, great parking and staff and very clean."

Reviewed on Dec 19, 2024

Unique Suites Hotel
Harrah's Metropolis Hotel & Casino
Harrah's Metropolis Hotel & Casino
3.5 out of 5
100 E Front St, Metropolis, IL
The price is $125 per night from Feb 6 to Feb 7
$125
includes taxes & fees
Feb 6 - Feb 7
Stay at this 3.5-star hotel in Metropolis. Enjoy free parking, 2 restaurants, and a casino. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,001 reviews)
"The hotel is decent and close to stores and restaurants. The casino slots are extremely tight and no free play was given for new members. After playing over $500 still no free play was added to the rewards card. Will not be returning to this casino but would stay at the hotel again if in the ..."

Reviewed on Jan 3, 2025

Harrah's Metropolis Hotel & Casino
Comfort Suites Mattoon
Comfort Suites Mattoon
2.5 out of 5
1408 Broadway Ave E, Mattoon, IL
The price is $114 per night from Jan 19 to Jan 20
$114
includes taxes & fees
Jan 19 - Jan 20
Book a stay at this business-friendly hotel in Mattoon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (668 reviews)
"clean, quiet, comfortable, at a reasoable price"

Reviewed on Dec 29, 2024

Comfort Suites Mattoon
Holiday Inn Express Metropolis, an IHG Hotel
Holiday Inn Express Metropolis, an IHG Hotel
2.5 out of 5
2179 East 5th Street, Metropolis, IL
The price is $115 per night from Jan 8 to Jan 9
$115
includes taxes & fees
Jan 8 - Jan 9
Book a stay at this business-friendly hotel in Metropolis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,003 reviews)
"Good service, decent room and good breakfast"

Reviewed on Jan 1, 2025

Holiday Inn Express Metropolis, an IHG Hotel
See all 881 properties in Southeast Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.