Search Cheap Flights to
Wytheville

Photo by Meng Fan

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Wytheville Flights as Low as $359

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Wed, Jul 16 - Wed, Jul 23
SJC
Norman Y. Mineta San Jose Intl.
ROA
Roanoke Regional
$359 Roundtrip, found 5 days ago
$359
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Jul 16 from Norman Y. Mineta San Jose Intl. to Roanoke Regional, returning Wed, Jul 23, priced at $359 found 5 days ago
Delta
Wed, Jun 25 - Tue, Jul 1
SJC
Norman Y. Mineta San Jose Intl.
ROA
Roanoke Regional
$379 Roundtrip, found 5 days ago
$379
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, Jun 25 from Norman Y. Mineta San Jose Intl. to Roanoke Regional, returning Tue, Jul 1, priced at $379 found 5 days ago
Delta
Wed, Jun 25 - Sun, Jun 29
SJC
Norman Y. Mineta San Jose Intl.
ROA
Roanoke Regional
$404 Roundtrip, found 5 days ago
$404
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, Jun 25 from Norman Y. Mineta San Jose Intl. to Roanoke Regional, returning Sun, Jun 29, priced at $404 found 5 days ago
American Airlines
Wed, Jul 16 - Sat, Jul 19
SJC
Norman Y. Mineta San Jose Intl.
ROA
Roanoke Regional
$404 Roundtrip, found 5 days ago
$404
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Jul 16 from Norman Y. Mineta San Jose Intl. to Roanoke Regional, returning Sat, Jul 19, priced at $404 found 5 days ago
Delta
Wed, Jun 25 - Mon, Jun 30
SJC
Norman Y. Mineta San Jose Intl.
ROA
Roanoke Regional
$409 Roundtrip, found 5 days ago
$409
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, Jun 25 from Norman Y. Mineta San Jose Intl. to Roanoke Regional, returning Mon, Jun 30, priced at $409 found 5 days ago
American Airlines
Wed, Jul 16 - Thu, Jul 24
SJC
Norman Y. Mineta San Jose Intl.
ROA
Roanoke Regional
$419 Roundtrip, found 5 days ago
$419
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Jul 16 from Norman Y. Mineta San Jose Intl. to Roanoke Regional, returning Thu, Jul 24, priced at $419 found 5 days ago
Delta
Tue, Apr 29 - Wed, May 7
MSP
Minneapolis - St. Paul Intl.
TRI
Tri-Cities Regional
$427 Roundtrip, found 3 days ago
$427
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Apr 29 from Minneapolis - St. Paul Intl. to Tri-Cities Regional, returning Wed, May 7, priced at $427 found 3 days ago
Delta
Wed, Apr 30 - Wed, May 7
MSP
Minneapolis - St. Paul Intl.
TRI
Tri-Cities Regional
$429 Roundtrip, found 3 days ago
$429
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Apr 30 from Minneapolis - St. Paul Intl. to Tri-Cities Regional, returning Wed, May 7, priced at $429 found 3 days ago
Delta
Tue, Apr 29 - Thu, May 8
MSP
Minneapolis - St. Paul Intl.
TRI
Tri-Cities Regional
$433 Roundtrip, found 3 days ago
$433
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Apr 29 from Minneapolis - St. Paul Intl. to Tri-Cities Regional, returning Thu, May 8, priced at $433 found 3 days ago
Delta
Wed, Apr 30 - Thu, May 8
MSP
Minneapolis - St. Paul Intl.
TRI
Tri-Cities Regional
$435 Roundtrip, found 3 days ago
$435
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Apr 30 from Minneapolis - St. Paul Intl. to Tri-Cities Regional, returning Thu, May 8, priced at $435 found 3 days ago
Delta
Sat, May 3 - Thu, May 8
MSP
Minneapolis - St. Paul Intl.
TRI
Tri-Cities Regional
$439 Roundtrip, found 3 days ago
$439
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, May 3 from Minneapolis - St. Paul Intl. to Tri-Cities Regional, returning Thu, May 8, priced at $439 found 3 days ago
American Airlines
Fri, May 2 - Mon, May 5
MSP
Minneapolis - St. Paul Intl.
TRI
Tri-Cities Regional
$442 Roundtrip, found 3 days ago
$442
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, May 2 from Minneapolis - St. Paul Intl. to Tri-Cities Regional, returning Mon, May 5, priced at $442 found 3 days ago
American Airlines
Sat, Mar 22 - Tue, Mar 25
CLT
Charlotte-Douglas Intl.
ROA
Roanoke Regional
$445 Roundtrip, found 20 hours ago
$445
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Sat, Mar 22 from Charlotte-Douglas Intl. to Roanoke Regional, returning Tue, Mar 25, priced at $445 found 20 hours ago
Delta
Fri, Jun 27 - Tue, Jul 1
SJC
Norman Y. Mineta San Jose Intl.
ROA
Roanoke Regional
$451 Roundtrip, found 5 days ago
$451
Roundtrip
found 5 days ago
Select Delta flight, departing Fri, Jun 27 from Norman Y. Mineta San Jose Intl. to Roanoke Regional, returning Tue, Jul 1, priced at $451 found 5 days ago
American Airlines
Tue, Mar 18 - Tue, Mar 25
CLT
Charlotte-Douglas Intl.
ROA
Roanoke Regional
$455 Roundtrip, found 20 hours ago
$455
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Tue, Mar 18 from Charlotte-Douglas Intl. to Roanoke Regional, returning Tue, Mar 25, priced at $455 found 20 hours ago
United
Fri, Jul 18 - Mon, Jul 21
SJC
Norman Y. Mineta San Jose Intl.
ROA
Roanoke Regional
$784 Roundtrip, found 1 day ago
$784
Roundtrip
found 1 day ago
Select United flight, departing Fri, Jul 18 from Norman Y. Mineta San Jose Intl. to Roanoke Regional, returning Mon, Jul 21, priced at $784 found 1 day ago

Cheap Flights to Wytheville

Fall in love at first flight with your vacation to Wytheville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Wytheville on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Wytheville, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Wytheville

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Wytheville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the ROA airport.

What is the cheapest month to fly to Wytheville?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Wytheville are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Wytheville?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Wytheville.

What airport is best to fly into Wytheville?

When you’re planning your trip to Wytheville, convenience is the name of the game. Luckily, Wytheville Virginia Highlands Airport is nearby so you can deplane and get going on checking off everything on your Wytheville must-do list.

How much are flights to Wytheville?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Wytheville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $359, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Wytheville?

The trick to saving a stack of cash on your flight to Wytheville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $359 right now, why wait?

Wytheville Flight Information
Destination airport
Roanoke Regional
Destination airport IATA code
ROA
Roundtrip price
$359

Last Minute Hotel Deals in Wytheville

Sleep Inn Wytheville I-77 and I-81
Sleep Inn Wytheville I-77 and I-81
2.5 out of 5
135 Nye Cir, Wytheville, VA
The price is $103 per night from Mar 18 to Mar 19
$103
includes taxes & fees
Mar 18 - Mar 19
Stay at this hotel in Wytheville. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,448 reviews)
"We spent one night on a road trip. The experience was very good. The staff was very helpful and check in was simple. The lobby was pleasant, fruit and water was available. The room was clean and pleasant. Great for our overnight stay,"

Reviewed on Mar 14, 2025

Sleep Inn Wytheville I-77 and I-81
Ramada by Wyndham Wytheville
Ramada by Wyndham Wytheville
2.5 out of 5
955 Peppers Ferry Rd, Wytheville, VA
The price is $69 per night from Mar 23 to Mar 24
$69
includes taxes & fees
Mar 23 - Mar 24
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the pool ...
8.2/10 Very Good! (1,100 reviews)
"Nice staff, convenient, good stay for the price."

Reviewed on Mar 14, 2025

Ramada by Wyndham Wytheville
Country Inn & Suites by Radisson, Wytheville, VA
Country Inn & Suites by Radisson, Wytheville, VA
3 out of 5
697 Peppers Ferry Road, Wytheville, VA
The price is $130 per night from Apr 15 to Apr 16
$130
includes taxes & fees
Apr 15 - Apr 16
Stay at this 3-star business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,001 reviews)
Great place to stay
"Great place to stay. There is quite a lot of highway noise, but the convenience of returning to the highway and restaurants close by make it worth the noise."

Reviewed on Mar 15, 2025

Country Inn & Suites by Radisson, Wytheville, VA
Holiday Inn Express and Suites Wytheville by IHG
Holiday Inn Express and Suites Wytheville by IHG
2.5 out of 5
165 Malin Dr, Wytheville, VA
The price is $155 per night from Mar 23 to Mar 24
$155
includes taxes & fees
Mar 23 - Mar 24
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,002 reviews)
"Wonderful staff. Big clean rooms. Only stayed I night while passing through but would definitely stay again."

Reviewed on Mar 15, 2025

Holiday Inn Express and Suites Wytheville by IHG
Tru by Hilton Wytheville
Tru by Hilton Wytheville
2.5 out of 5
245 Boyd Ave, Wytheville, VA
The price is $125 per night from Mar 23 to Mar 24
$125
includes taxes & fees
Mar 23 - Mar 24
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (886 reviews)
Super clean and comfortable!
"Very clean! There are things to do for the family, even if just stopping for the night while traveling. We had our small pups with us, there is a great potty station. Will definitely choose Tru by Hilton again."

Reviewed on Mar 4, 2025

Tru by Hilton Wytheville
Travelodge by Wyndham Wytheville
Travelodge by Wyndham Wytheville
2 out of 5
140 Lithia Rd, Wytheville, VA
The price is $78 per night from Mar 18 to Mar 19
$78
includes taxes & fees
Mar 18 - Mar 19
Book a stay at this business-friendly motel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,344 reviews)
"We stay here a couple times a year in our travels and this place is always improving."

Reviewed on Mar 12, 2025

Travelodge by Wyndham Wytheville
Comfort Suites Wytheville
Comfort Suites Wytheville
2.5 out of 5
695 Peppers Ferry Rd, Wytheville, VA
The price is $112 per night from Apr 6 to Apr 7
$112
includes taxes & fees
Apr 6 - Apr 7
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the ...
8.8/10 Excellent! (1,005 reviews)
10 out of 10
"Very clean, quiet, comfortable bed and a great breakfast."

Reviewed on Mar 16, 2025

Comfort Suites Wytheville
La Quinta Inn & Suites by Wyndham Wytheville
La Quinta Inn & Suites by Wyndham Wytheville
2.5 out of 5
1800 East Main Street, Wytheville, VA
The price is $111 per night from Apr 15 to Apr 16
$111
includes taxes & fees
Apr 15 - Apr 16
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,001 reviews)
"It was a good over night stay"

Reviewed on Mar 1, 2025

La Quinta Inn & Suites by Wyndham Wytheville
See all 307 properties in Wytheville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.