Search Cheap Flights to
Wytheville

Photo by Meng Fan

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Wytheville Flights as Low as $213

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

United
Fri, Jul 18 - Tue, Jul 22
ORD
O'Hare Intl.
ROA
Roanoke Regional
$213 Roundtrip, found 1 day ago
$213
Roundtrip
found 1 day ago
Select United flight, departing Fri, Jul 18 from O'Hare Intl. to Roanoke Regional, returning Tue, Jul 22, priced at $213 found 1 day ago
United
Sat, Jul 12 - Sat, Jul 19
ORD
O'Hare Intl.
ROA
Roanoke Regional
$219 Roundtrip, found 1 day ago
$219
Roundtrip
found 1 day ago
Select United flight, departing Sat, Jul 12 from O'Hare Intl. to Roanoke Regional, returning Sat, Jul 19, priced at $219 found 1 day ago
Delta
Tue, Jul 1 - Fri, Jul 4
DFW
Dallas-Fort Worth Intl.
ROA
Roanoke Regional
$220 Roundtrip, found 1 day ago
$220
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jul 1 from Dallas-Fort Worth Intl. to Roanoke Regional, returning Fri, Jul 4, priced at $220 found 1 day ago
United
Thu, Jul 10 - Sat, Jul 19
ORD
O'Hare Intl.
ROA
Roanoke Regional
$222 Roundtrip, found 1 day ago
$222
Roundtrip
found 1 day ago
Select United flight, departing Thu, Jul 10 from O'Hare Intl. to Roanoke Regional, returning Sat, Jul 19, priced at $222 found 1 day ago
American Airlines
Wed, Aug 20 - Mon, Sep 1
BUF
Buffalo Niagara Intl.
ROA
Roanoke Regional
$229 Roundtrip, found 21 hours ago
$229
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Wed, Aug 20 from Buffalo Niagara Intl. to Roanoke Regional, returning Mon, Sep 1, priced at $229 found 21 hours ago
Delta
Fri, Jul 4 - Fri, Jul 18
SYR
Hancock Intl.
ROA
Roanoke Regional
$232 Roundtrip, found 23 hours ago
$232
Roundtrip
found 23 hours ago
Select Delta flight, departing Fri, Jul 4 from Hancock Intl. to Roanoke Regional, returning Fri, Jul 18, priced at $232 found 23 hours ago
Bargain Flight
Sat, May 31 - Thu, Jun 5
PHL
Philadelphia Intl.
ROA
Roanoke Regional
$240 Roundtrip, found 7 hours ago
$240
Roundtrip
found 7 hours ago
Select Bargain Flight flight, departing Sat, May 31 from Philadelphia Intl. to Roanoke Regional, returning Thu, Jun 5, priced at $240 found 7 hours ago
Delta
Tue, Jun 24 - Fri, Jul 4
DAL
Love Field
ROA
Roanoke Regional
$241 Roundtrip, found 2 days ago
$241
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Jun 24 from Love Field to Roanoke Regional, returning Fri, Jul 4, priced at $241 found 2 days ago
Bargain Flight
Fri, Jun 13 - Sun, Jun 15
AUS
Austin-Bergstrom Intl.
ROA
Roanoke Regional
$252 Roundtrip, found 13 hours ago
$252
Roundtrip
found 13 hours ago
Select Bargain Flight flight, departing Fri, Jun 13 from Austin-Bergstrom Intl. to Roanoke Regional, returning Sun, Jun 15, priced at $252 found 13 hours ago
American Airlines
Fri, Jun 13 - Mon, Jun 16
ORD
O'Hare Intl.
TRI
Tri-Cities Regional
$278 Roundtrip, found 8 hours ago
$278
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Fri, Jun 13 from O'Hare Intl. to Tri-Cities Regional, returning Mon, Jun 16, priced at $278 found 8 hours ago
Bargain Flight
Tue, Jun 3 - Tue, Jun 10
LGA
LaGuardia
ROA
Roanoke Regional
$281 Roundtrip, found 1 day ago
$281
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Tue, Jun 3 from LaGuardia to Roanoke Regional, returning Tue, Jun 10, priced at $281 found 1 day ago
Delta
Tue, Oct 14 - Tue, Oct 21
LGA
LaGuardia
TRI
Tri-Cities Regional
$335 Roundtrip, found 14 hours ago
$335
Roundtrip
found 14 hours ago
Select Delta flight, departing Tue, Oct 14 from LaGuardia to Tri-Cities Regional, returning Tue, Oct 21, priced at $335 found 14 hours ago
Delta
Tue, Aug 5 - Tue, Aug 12
DAL
Love Field
TRI
Tri-Cities Regional
$359 Roundtrip, found 2 days ago
$359
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Aug 5 from Love Field to Tri-Cities Regional, returning Tue, Aug 12, priced at $359 found 2 days ago
American Airlines
Wed, Jun 18 - Mon, Jul 14
SFO
San Francisco Intl.
ROA
Roanoke Regional
$385 Roundtrip, found 1 day ago
$385
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Jun 18 from San Francisco Intl. to Roanoke Regional, returning Mon, Jul 14, priced at $385 found 1 day ago
American Airlines
Wed, May 28 - Sun, Jul 20
SFO
San Francisco Intl.
TRI
Tri-Cities Regional
$404 Roundtrip, found 4 days ago
$404
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, May 28 from San Francisco Intl. to Tri-Cities Regional, returning Sun, Jul 20, priced at $404 found 4 days ago
Delta
Wed, Aug 6 - Sun, Aug 10
DFW
Dallas-Fort Worth Intl.
TRI
Tri-Cities Regional
$440 Roundtrip, found 2 days ago
$440
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Aug 6 from Dallas-Fort Worth Intl. to Tri-Cities Regional, returning Sun, Aug 10, priced at $440 found 2 days ago

Cheap Flights to Wytheville

Fall in love at first flight with your vacation to Wytheville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Wytheville on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Wytheville, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Wytheville

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Wytheville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the ROA airport.

What is the cheapest month to fly to Wytheville?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Wytheville are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Wytheville?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 13 to choose from for your flight to Wytheville.

What airport is best to fly into Wytheville?

When you’re planning your trip to Wytheville, convenience is the name of the game. Luckily, Wytheville Virginia Highlands Airport is nearby so you can deplane and get going on checking off everything on your Wytheville must-do list.

How much are flights to Wytheville?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Wytheville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $213, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Wytheville?

The trick to saving a stack of cash on your flight to Wytheville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $213 right now, why wait?

Wytheville Flight Information
Destination airport
Roanoke Regional
Destination airport IATA code
ROA
Roundtrip price
$212

Last Minute Hotel Deals in Wytheville

Ramada by Wyndham Wytheville
Ramada by Wyndham Wytheville
2.5 out of 5
955 Peppers Ferry Rd, Wytheville, VA
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the pool ...
8.2/10 Very Good! (1,203 reviews)
Comfortable and quiet in Wytheville
"Quiet, comfortable, and clean room, basic breakfast, weak Wi-Fi. I'll stay here again."

Reviewed on May 21, 2025

Get rates
Ramada by Wyndham Wytheville
Sleep Inn Wytheville I-77 and I-81
Sleep Inn Wytheville I-77 and I-81
2.5 out of 5
135 Nye Cir, Wytheville, VA
Stay at this hotel in Wytheville. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,566 reviews)
"Clean, attractively furnished, and an excellent breakfast."

Reviewed on May 22, 2025

Get rates
Sleep Inn Wytheville I-77 and I-81
Days Inn by Wyndham Wytheville
Days Inn by Wyndham Wytheville
2 out of 5
150 Malin Dr, I-81 and I-77 Exit 73, Wytheville, VA
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,002 reviews)
"Breakfast area and they were out of stuff. Only had the one worker at the front desk and you were out of food in The breakfast area."

Reviewed on May 20, 2025

Get rates
Days Inn by Wyndham Wytheville
Country Inn & Suites by Radisson, Wytheville, VA
Country Inn & Suites by Radisson, Wytheville, VA
3 out of 5
697 Peppers Ferry Road, Wytheville, VA
Stay at this 3-star business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,001 reviews)
"👍"

Reviewed on May 22, 2025

Get rates
Country Inn & Suites by Radisson, Wytheville, VA
Comfort Suites Wytheville
Comfort Suites Wytheville
2.5 out of 5
695 Peppers Ferry Rd, Wytheville, VA
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the ...
8.8/10 Excellent! (1,001 reviews)
"Very good."

Reviewed on May 20, 2025

Get rates
Comfort Suites Wytheville
Travelodge by Wyndham Wytheville
Travelodge by Wyndham Wytheville
2 out of 5
140 Lithia Rd, Wytheville, VA
Book a stay at this business-friendly motel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,338 reviews)
"Great, convenient and reasonably priced place to stay. Excellent for pets. Will stay there again. A++++++"

Reviewed on May 19, 2025

Get rates
Travelodge by Wyndham Wytheville
Super 8 by Wyndham Wytheville
Super 8 by Wyndham Wytheville
2 out of 5
130 Nye Circle, I-77 exit 41, Wytheville, VA
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,010 reviews)
"Great staff, friendly service."

Reviewed on May 22, 2025

Get rates
Super 8 by Wyndham Wytheville
La Quinta Inn & Suites by Wyndham Wytheville
La Quinta Inn & Suites by Wyndham Wytheville
3 out of 5
1800 East Main Street, Wytheville, VA
Stay at this 3-star business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,002 reviews)
"Outside needs to be cleaned up some"

Reviewed on May 18, 2025

Get rates
La Quinta Inn & Suites by Wyndham Wytheville
See all 327 properties in Wytheville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.