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Wytheville

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Wytheville Flights as Low as $217

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Tue, Aug 19 - Sun, Aug 31
BUF
Buffalo Niagara Intl.
ROA
Roanoke Regional
$217 Roundtrip, found 20 hours ago
$217
Roundtrip
found 20 hours ago
Select Delta flight, departing Tue, Aug 19 from Buffalo Niagara Intl. to Roanoke Regional, returning Sun, Aug 31, priced at $217 found 20 hours ago
Delta
Sat, Aug 30 - Sun, Aug 31
BOS
Logan Intl.
ROA
Roanoke Regional
$220 Roundtrip, found 7 hours ago
$220
Roundtrip
found 7 hours ago
Select Delta flight, departing Sat, Aug 30 from Logan Intl. to Roanoke Regional, returning Sun, Aug 31, priced at $220 found 7 hours ago
American Airlines
Tue, Aug 26 - Sat, Aug 30
BOS
Logan Intl.
ROA
Roanoke Regional
$225 Roundtrip, found 2 days ago
$225
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Aug 26 from Logan Intl. to Roanoke Regional, returning Sat, Aug 30, priced at $225 found 2 days ago
United
Tue, Aug 26 - Sat, Aug 30
BOS
Logan Intl.
ROA
Roanoke Regional
$228 Roundtrip, found 2 days ago
$228
Roundtrip
found 2 days ago
Select United flight, departing Tue, Aug 26 from Logan Intl. to Roanoke Regional, returning Sat, Aug 30, priced at $228 found 2 days ago
American Airlines
Wed, Sep 10 - Sat, Sep 13
ALB
Albany Intl.
ROA
Roanoke Regional
$229 Roundtrip, found 6 hours ago
$229
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Wed, Sep 10 from Albany Intl. to Roanoke Regional, returning Sat, Sep 13, priced at $229 found 6 hours ago
United
Wed, Sep 10 - Sat, Sep 13
ALB
Albany Intl.
ROA
Roanoke Regional
$229 Roundtrip, found 6 hours ago
$229
Roundtrip
found 6 hours ago
Select United flight, departing Wed, Sep 10 from Albany Intl. to Roanoke Regional, returning Sat, Sep 13, priced at $229 found 6 hours ago
Delta
Mon, Sep 8 - Tue, Sep 16
ALB
Albany Intl.
ROA
Roanoke Regional
$230 Roundtrip, found 5 days ago
$230
Roundtrip
found 5 days ago
Select Delta flight, departing Mon, Sep 8 from Albany Intl. to Roanoke Regional, returning Tue, Sep 16, priced at $230 found 5 days ago
Delta
Thu, Sep 11 - Tue, Sep 16
ALB
Albany Intl.
ROA
Roanoke Regional
$232 Roundtrip, found 23 hours ago
$232
Roundtrip
found 23 hours ago
Select Delta flight, departing Thu, Sep 11 from Albany Intl. to Roanoke Regional, returning Tue, Sep 16, priced at $232 found 23 hours ago
American Airlines
Sat, Oct 18 - Tue, Oct 21
DEN
Denver Intl.
ROA
Roanoke Regional
$251 Roundtrip, found 1 day ago
$251
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Oct 18 from Denver Intl. to Roanoke Regional, returning Tue, Oct 21, priced at $251 found 1 day ago
American Airlines
Tue, Aug 12 - Tue, Aug 19
COS
Colorado Springs
ROA
Roanoke Regional
$272 Roundtrip, found 1 day ago
$272
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Aug 12 from Colorado Springs to Roanoke Regional, returning Tue, Aug 19, priced at $272 found 1 day ago
Delta
Tue, Sep 9 - Tue, Sep 16
BUF
Buffalo Niagara Intl.
TRI
Tri-Cities Regional
$289 Roundtrip, found 5 days ago
$289
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Sep 9 from Buffalo Niagara Intl. to Tri-Cities Regional, returning Tue, Sep 16, priced at $289 found 5 days ago
American Airlines
Tue, Aug 5 - Sat, Aug 9
ORD
O'Hare Intl.
TRI
Tri-Cities Regional
$307 Roundtrip, found 5 days ago
$307
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Aug 5 from O'Hare Intl. to Tri-Cities Regional, returning Sat, Aug 9, priced at $307 found 5 days ago
United
Tue, Jul 29 - Sat, Aug 2
ORD
O'Hare Intl.
ROA
Roanoke Regional
$318 Roundtrip, found 1 day ago
$318
Roundtrip
found 1 day ago
Select United flight, departing Tue, Jul 29 from O'Hare Intl. to Roanoke Regional, returning Sat, Aug 2, priced at $318 found 1 day ago
United
Tue, Sep 16 - Tue, Sep 23
SHV
Shreveport Regional
ROA
Roanoke Regional
$320 Roundtrip, found 1 day ago
$320
Roundtrip
found 1 day ago
Select United flight, departing Tue, Sep 16 from Shreveport Regional to Roanoke Regional, returning Tue, Sep 23, priced at $320 found 1 day ago
American Airlines
Sat, Sep 27 - Mon, Sep 29
VPS
Northwest Florida Regional
ROA
Roanoke Regional
$327 Roundtrip, found 2 hours ago
$327
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Sep 27 from Northwest Florida Regional to Roanoke Regional, returning Mon, Sep 29, priced at $327 found 2 hours ago
Delta
Mon, Aug 4 - Sun, Aug 10
BOS
Logan Intl.
TRI
Tri-Cities Regional
$352 Roundtrip, found 14 hours ago
$352
Roundtrip
found 14 hours ago
Select Delta flight, departing Mon, Aug 4 from Logan Intl. to Tri-Cities Regional, returning Sun, Aug 10, priced at $352 found 14 hours ago

Cheap Flights to Wytheville

Fall in love at first flight with your vacation to Wytheville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Wytheville on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Wytheville, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Wytheville

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Wytheville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the ROA airport.

What is the cheapest month to fly to Wytheville?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Wytheville are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Wytheville?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Wytheville.

What airport is best to fly into Wytheville?

When you’re planning your trip to Wytheville, convenience is the name of the game. Luckily, Wytheville Virginia Highlands Airport is nearby so you can deplane and get going on checking off everything on your Wytheville must-do list.

How much are flights to Wytheville?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Wytheville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $217, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Wytheville?

The trick to saving a stack of cash on your flight to Wytheville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $217 right now, why wait?

Wytheville Flight Information
Destination airport
Roanoke Regional
Destination airport IATA code
ROA
Roundtrip price
$217

Last Minute Hotel Deals in Wytheville

Ramada by Wyndham Wytheville

Ramada by Wyndham Wytheville

2.5 out of 5
955 Peppers Ferry Rd, Wytheville, VA
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the pool ...
8.2/10 Very Good! (1,332 reviews)
"Great Pool. Very friendly staff."

Reviewed on Jul 27, 2025

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Ramada by Wyndham Wytheville
Days Inn by Wyndham Wytheville

Days Inn by Wyndham Wytheville

2 out of 5
150 Malin Dr, I-81 and I-77 Exit 73, Wytheville, VA
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,019 reviews)
"Great!"

Reviewed on Jul 23, 2025

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Days Inn by Wyndham Wytheville
Sleep Inn Wytheville I-77 and I-81

Sleep Inn Wytheville I-77 and I-81

2.5 out of 5
135 Nye Cir, Wytheville, VA
Stay at this hotel in Wytheville. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,623 reviews)
"Hotel is nice, in a great location, always a great selection of snacks and drinks as well as breakfast foods. Only downfall is that the breakfast space is very small with only about 4 tables so there isn’t always a seat available for breakfast."

Reviewed on Jul 26, 2025

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Sleep Inn Wytheville I-77 and I-81
Travelodge by Wyndham Wytheville

Travelodge by Wyndham Wytheville

2 out of 5
140 Lithia Rd, Wytheville, VA
Book a stay at this business-friendly motel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,334 reviews)
"Nice place to stay"

Reviewed on Jul 13, 2025

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Travelodge by Wyndham Wytheville
Country Inn & Suites by Radisson, Wytheville, VA

Country Inn & Suites by Radisson, Wytheville, VA

3 out of 5
697 Peppers Ferry Road, Wytheville, VA
Stay at this 3-star business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,021 reviews)
"The lady attending the breakfast room was very kind and pleasant."

Reviewed on Jul 26, 2025

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Country Inn & Suites by Radisson, Wytheville, VA
Comfort Suites Wytheville

Comfort Suites Wytheville

2.5 out of 5
695 Peppers Ferry Rd, Wytheville, VA
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the ...
8.6/10 Excellent! (1,016 reviews)
Highly recommend !
"Very nice and clean, comfortable beds, slept well."

Reviewed on Jul 26, 2025

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Comfort Suites Wytheville
Super 8 by Wyndham Wytheville

Super 8 by Wyndham Wytheville

2 out of 5
130 Nye Circle, I-77 exit 41, Wytheville, VA
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,008 reviews)
"Outstanding value. Property is older but the room has been updated (be aware shower/commode area is small/cramped which could be an issue for some). Shower area fan was loud but not audible in the room with ac running. Staff was very friendly and welcoming. Nice Asian restaurant across parking lot. ..."

Reviewed on Jul 25, 2025

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Super 8 by Wyndham Wytheville
Tru by Hilton Wytheville

Tru by Hilton Wytheville

2.5 out of 5
245 Boyd Ave, Wytheville, VA
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (980 reviews)
"Excellent staff. Amazing breakfast. Very modern. Not sure if my small room is a thing, or if it was small because I booked last minute."

Reviewed on Jul 25, 2025

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Tru by Hilton Wytheville
See all 370 properties in Wytheville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.