Search Cheap Flights to
Wytheville

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Wytheville Flights as Low as $219

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Sat, May 10 - Mon, May 12
CLE
Hopkins Intl.
ROA
Roanoke Regional
$219 Roundtrip, found 17 hours ago
$219
Roundtrip
found 17 hours ago
Select Delta flight, departing Sat, May 10 from Hopkins Intl. to Roanoke Regional, returning Mon, May 12, priced at $219 found 17 hours ago
Delta
Wed, May 7 - Mon, May 12
CLE
Hopkins Intl.
ROA
Roanoke Regional
$224 Roundtrip, found 17 hours ago
$224
Roundtrip
found 17 hours ago
Select Delta flight, departing Wed, May 7 from Hopkins Intl. to Roanoke Regional, returning Mon, May 12, priced at $224 found 17 hours ago
United
Fri, May 9 - Mon, May 12
CLE
Hopkins Intl.
ROA
Roanoke Regional
$232 Roundtrip, found 17 hours ago
$232
Roundtrip
found 17 hours ago
Select United flight, departing Fri, May 9 from Hopkins Intl. to Roanoke Regional, returning Mon, May 12, priced at $232 found 17 hours ago
United
Fri, May 9 - Mon, May 12
PIT
Pittsburgh Intl.
ROA
Roanoke Regional
$234 Roundtrip, found 17 hours ago
$234
Roundtrip
found 17 hours ago
Select United flight, departing Fri, May 9 from Pittsburgh Intl. to Roanoke Regional, returning Mon, May 12, priced at $234 found 17 hours ago
Delta
Sat, May 10 - Tue, May 13
PBI
Palm Beach Intl.
ROA
Roanoke Regional
$249 Roundtrip, found 1 day ago
$249
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, May 10 from Palm Beach Intl. to Roanoke Regional, returning Tue, May 13, priced at $249 found 1 day ago
Delta
Wed, May 7 - Tue, May 13
PBI
Palm Beach Intl.
ROA
Roanoke Regional
$253 Roundtrip, found 1 day ago
$253
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, May 7 from Palm Beach Intl. to Roanoke Regional, returning Tue, May 13, priced at $253 found 1 day ago
Delta
Tue, May 6 - Mon, May 12
CLE
Hopkins Intl.
ROA
Roanoke Regional
$258 Roundtrip, found 17 hours ago
$258
Roundtrip
found 17 hours ago
Select Delta flight, departing Tue, May 6 from Hopkins Intl. to Roanoke Regional, returning Mon, May 12, priced at $258 found 17 hours ago
United
Fri, May 9 - Mon, May 12
PIT
Pittsburgh Intl.
ROA
Roanoke Regional
$272 Roundtrip, found 17 hours ago
$272
Roundtrip
found 17 hours ago
Select United flight, departing Fri, May 9 from Pittsburgh Intl. to Roanoke Regional, returning Mon, May 12, priced at $272 found 17 hours ago
Delta
Fri, May 9 - Mon, May 12
CLE
Hopkins Intl.
ROA
Roanoke Regional
$274 Roundtrip, found 17 hours ago
$274
Roundtrip
found 17 hours ago
Select Delta flight, departing Fri, May 9 from Hopkins Intl. to Roanoke Regional, returning Mon, May 12, priced at $274 found 17 hours ago
United
Fri, May 9 - Mon, May 12
CLE
Hopkins Intl.
ROA
Roanoke Regional
$279 Roundtrip, found 17 hours ago
$279
Roundtrip
found 17 hours ago
Select United flight, departing Fri, May 9 from Hopkins Intl. to Roanoke Regional, returning Mon, May 12, priced at $279 found 17 hours ago
American Airlines
Sat, May 10 - Mon, May 12
PIT
Pittsburgh Intl.
ROA
Roanoke Regional
$283 Roundtrip, found 17 hours ago
$283
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Sat, May 10 from Pittsburgh Intl. to Roanoke Regional, returning Mon, May 12, priced at $283 found 17 hours ago
Delta
Tue, May 6 - Tue, May 13
PBI
Palm Beach Intl.
ROA
Roanoke Regional
$283 Roundtrip, found 1 day ago
$283
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, May 6 from Palm Beach Intl. to Roanoke Regional, returning Tue, May 13, priced at $283 found 1 day ago
Delta
Fri, May 9 - Mon, May 12
CLE
Hopkins Intl.
ROA
Roanoke Regional
$284 Roundtrip, found 17 hours ago
$284
Roundtrip
found 17 hours ago
Select Delta flight, departing Fri, May 9 from Hopkins Intl. to Roanoke Regional, returning Mon, May 12, priced at $284 found 17 hours ago
Delta
Thu, May 8 - Mon, May 12
CLE
Hopkins Intl.
ROA
Roanoke Regional
$288 Roundtrip, found 17 hours ago
$288
Roundtrip
found 17 hours ago
Select Delta flight, departing Thu, May 8 from Hopkins Intl. to Roanoke Regional, returning Mon, May 12, priced at $288 found 17 hours ago
Delta
Tue, May 6 - Tue, May 13
LGA
LaGuardia
ROA
Roanoke Regional
$315 Roundtrip, found 1 day ago
$315
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, May 6 from LaGuardia to Roanoke Regional, returning Tue, May 13, priced at $315 found 1 day ago
American Airlines
Sat, May 10 - Tue, May 13
CAK
Akron-Canton
ROA
Roanoke Regional
$464 Roundtrip, found 17 hours ago
$464
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Sat, May 10 from Akron-Canton to Roanoke Regional, returning Tue, May 13, priced at $464 found 17 hours ago

Cheap Flights to Wytheville

Fall in love at first flight with your vacation to Wytheville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Wytheville on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Wytheville, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Wytheville

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Wytheville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the ROA airport.

What is the cheapest month to fly to Wytheville?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Wytheville are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Wytheville?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Wytheville.

What airport is best to fly into Wytheville?

When you’re planning your trip to Wytheville, convenience is the name of the game. Luckily, Wytheville Virginia Highlands Airport is nearby so you can deplane and get going on checking off everything on your Wytheville must-do list.

How much are flights to Wytheville?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Wytheville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $219, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Wytheville?

The trick to saving a stack of cash on your flight to Wytheville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $219 right now, why wait?

Wytheville Flight Information
Destination airport
Tri-Cities Regional
Destination airport IATA code
TRI
Roundtrip price
$356

Last Minute Hotel Deals in Wytheville

Sleep Inn Wytheville I-77 and I-81
Sleep Inn Wytheville I-77 and I-81
2.5 out of 5
135 Nye Cir, Wytheville, VA
The price is $103 per night from Apr 14 to Apr 15
$103
includes taxes & fees
Apr 14 - Apr 15
Stay at this hotel in Wytheville. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,482 reviews)
"Very nice clean and quiet"

Reviewed on Apr 8, 2025

Sleep Inn Wytheville I-77 and I-81
Ramada by Wyndham Wytheville
Ramada by Wyndham Wytheville
2.5 out of 5
955 Peppers Ferry Rd, Wytheville, VA
The price is $69 per night from Apr 20 to Apr 21
$69
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the pool ...
8.2/10 Very Good! (1,144 reviews)
"The bed was very comfortable. The room was clean. The breakfast was excellent, many options. I liked having the gas station and restaurants right next to it. A community center just down the road was great for a workout."

Reviewed on Apr 11, 2025

Ramada by Wyndham Wytheville
Travelodge by Wyndham Wytheville
Travelodge by Wyndham Wytheville
2 out of 5
140 Lithia Rd, Wytheville, VA
The price is $81 per night from Apr 14 to Apr 15
$81
includes taxes & fees
Apr 14 - Apr 15
Book a stay at this business-friendly motel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,343 reviews)
"I have stayed there several times and it has always been a good experience"

Reviewed on Apr 7, 2025

Travelodge by Wyndham Wytheville
Country Inn & Suites by Radisson, Wytheville, VA
Country Inn & Suites by Radisson, Wytheville, VA
3 out of 5
697 Peppers Ferry Road, Wytheville, VA
The price is $134 per night from Apr 14 to Apr 15
$134
includes taxes & fees
Apr 14 - Apr 15
Stay at this 3-star business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,003 reviews)
"Good"

Reviewed on Apr 12, 2025

Country Inn & Suites by Radisson, Wytheville, VA
Comfort Suites Wytheville
Comfort Suites Wytheville
2.5 out of 5
695 Peppers Ferry Rd, Wytheville, VA
The price is $115 per night from May 11 to May 12
$115
includes taxes & fees
May 11 - May 12
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the ...
8.6/10 Excellent! (1,000 reviews)
"Clean, spacious room"

Reviewed on Apr 7, 2025

Comfort Suites Wytheville
Days Inn by Wyndham Wytheville
Days Inn by Wyndham Wytheville
2 out of 5
150 Malin Dr, I-81 and I-77 Exit 73, Wytheville, VA
The price is $64 per night from Apr 27 to Apr 28
$64
includes taxes & fees
Apr 27 - Apr 28
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,004 reviews)
Great value.
"Very nice hotel. Great value for the cost of the room. Will stay again in the future."

Reviewed on Apr 9, 2025

Days Inn by Wyndham Wytheville
Tru by Hilton Wytheville
Tru by Hilton Wytheville
2.5 out of 5
245 Boyd Ave, Wytheville, VA
The price is $126 per night from May 11 to May 12
$126
includes taxes & fees
May 11 - May 12
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (915 reviews)
"Very good breakfast, nice pool, and clean hotel"

Reviewed on Apr 11, 2025

Tru by Hilton Wytheville
Holiday Inn Express and Suites Wytheville by IHG
Holiday Inn Express and Suites Wytheville by IHG
2.5 out of 5
165 Malin Dr, Wytheville, VA
The price is $160 per night from Apr 15 to Apr 16
$160
includes taxes & fees
Apr 15 - Apr 16
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,001 reviews)
"Nice clean spot for overnight"

Reviewed on Apr 6, 2025

Holiday Inn Express and Suites Wytheville by IHG
See all 317 properties in Wytheville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.