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De Soto Vacation Packages

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De Soto Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.
Baymont by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport

2.5 out of 5
per person
Apr 30 - May 2
found 1 hour ago
Roundtrip flight included
St. Louis (STL) to Des Moines (DSM)
Book a stay at this family-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Jordan Creek Town Center and Wells Fargo Arena are located nearby.
Comfort Inn and Suites Ames near ISU Campus

Comfort Inn and Suites Ames near ISU Campus

2.5 out of 5
per person
Apr 30 - May 2
found 1 hour ago
Roundtrip non-stop flight included
St. Louis (STL) to Des Moines (DSM)
Book a stay at this golf hotel in Ames. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Jack Trice Stadium and Reiman Gardens are located nearby.
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
per person
Apr 30 - May 2
found 1 hour ago
Roundtrip flight included
St. Louis (STL) to Des Moines (DSM)
Stay at this 3-star business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Wells Fargo Arena and Iowa State Fairgrounds are located nearby.
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
per person
Apr 30 - May 2
found 1 hour ago
Roundtrip flight included
St. Louis (STL) to Des Moines (DSM)
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Wells Fargo Arena and Air Lanes Bowling Center are located nearby.
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
per person
Apr 30 - May 2
found 1 hour ago
Roundtrip flight included
St. Louis (STL) to Des Moines (DSM)
Stay at this 4.5-star luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Wells Fargo Arena and Iowa State Fairgrounds are located nearby.
Wildwood Lodge

Wildwood Lodge

3 out of 5
per person
Apr 30 - May 2
found 1 hour ago
Roundtrip flight included
St. Louis (STL) to Des Moines (DSM)
Stay at this 3-star hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Jordan Creek Town Center and Clive Aquatic Center are located nearby.
Hyatt Place Des Moines/Downtown

Hyatt Place Des Moines/Downtown

3 out of 5
per person
Apr 30 - May 2
found 1 hour ago
Roundtrip flight included
St. Louis (STL) to Des Moines (DSM)
Stay at this 3-star business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Wells Fargo Arena and Iowa State Fairgrounds are located nearby.
Quality Inn & Suites Ames Conference Center Near ISU Campus

Quality Inn & Suites Ames Conference Center Near ISU Campus

2.5 out of 5
per person
Apr 30 - May 2
found 1 hour ago
Roundtrip non-stop flight included
St. Louis (STL) to Des Moines (DSM)
Book a stay at this business-friendly hotel in Ames. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Octagon Center for the Arts and Main Street Cultural District are located nearby.

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, May 14 - Sat, May 24
DEN
Denver Intl.
DSM
Des Moines Intl.
$119 Roundtrip, found 6 days ago
$119
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Wed, May 14 from Denver Intl. to Des Moines Intl., returning Sat, May 24, priced at $119 found 6 days ago
Frontier Airlines
Fri, Mar 28 - Fri, Apr 4
ORD
O'Hare Intl.
DSM
Des Moines Intl.
$211 Roundtrip, found 6 days ago
$211
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Fri, Mar 28 from O'Hare Intl. to Des Moines Intl., returning Fri, Apr 4, priced at $211 found 6 days ago
Frontier Airlines
Wed, Apr 23 - Wed, Apr 30
DFW
Dallas-Fort Worth Intl.
DSM
Des Moines Intl.
$251 Roundtrip, found 4 days ago
$251
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Wed, Apr 23 from Dallas-Fort Worth Intl. to Des Moines Intl., returning Wed, Apr 30, priced at $251 found 4 days ago
Frontier Airlines
Fri, Mar 28 - Fri, Apr 4
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$269 Roundtrip, found 3 days ago
$269
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Fri, Mar 28 from Sky Harbor Intl. to Des Moines Intl., returning Fri, Apr 4, priced at $269 found 3 days ago