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De Soto

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De Soto Flights as Low as $58

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, Mar 25 - Sat, Mar 28
DEN
Denver Intl.
DSM
Des Moines Intl.
$58 Roundtrip, found 19 hours ago
$58
Roundtrip
found 19 hours ago
Select Frontier Airlines flight, departing Wed, Mar 25 from Denver Intl. to Des Moines Intl., returning Sat, Mar 28, priced at $58 found 19 hours ago
Frontier Airlines
Sat, Mar 14 - Sat, Mar 21
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$112 Roundtrip, found 1 day ago
$112
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sat, Mar 14 from Sky Harbor Intl. to Des Moines Intl., returning Sat, Mar 21, priced at $112 found 1 day ago
Frontier Airlines
Wed, Mar 11 - Wed, Mar 25
IAH
George Bush Intercontinental
DSM
Des Moines Intl.
$160 Roundtrip, found 1 day ago
$160
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Mar 11 from George Bush Intercontinental to Des Moines Intl., returning Wed, Mar 25, priced at $160 found 1 day ago
Frontier Airlines
Thu, Apr 16 - Mon, May 4
PHL
Philadelphia Intl.
DSM
Des Moines Intl.
$172 Roundtrip, found 6 days ago
$172
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Thu, Apr 16 from Philadelphia Intl. to Des Moines Intl., returning Mon, May 4, priced at $172 found 6 days ago
United
Wed, Mar 25 - Wed, Apr 1
DEN
Denver Intl.
DSM
Des Moines Intl.
$181 Roundtrip, found 3 hours ago
$181
Roundtrip
found 3 hours ago
Select United flight, departing Wed, Mar 25 from Denver Intl. to Des Moines Intl., returning Wed, Apr 1, priced at $181 found 3 hours ago
Frontier Airlines
Thu, Apr 23 - Fri, May 15
DTW
Detroit Metropolitan Wayne County
DSM
Des Moines Intl.
$191 Roundtrip, found 3 hours ago
$191
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Thu, Apr 23 from Detroit Metropolitan Wayne County to Des Moines Intl., returning Fri, May 15, priced at $191 found 3 hours ago
Delta
Wed, Mar 25 - Wed, Apr 1
DEN
Denver Intl.
DSM
Des Moines Intl.
$201 Roundtrip, found 3 hours ago
$201
Roundtrip
found 3 hours ago
Select Delta flight, departing Wed, Mar 25 from Denver Intl. to Des Moines Intl., returning Wed, Apr 1, priced at $201 found 3 hours ago
Frontier Airlines
Wed, Mar 25 - Mon, Apr 6
LAX
Los Angeles Intl.
DSM
Des Moines Intl.
$223 Roundtrip, found 9 hours ago
$223
Roundtrip
found 9 hours ago
Select Frontier Airlines flight, departing Wed, Mar 25 from Los Angeles Intl. to Des Moines Intl., returning Mon, Apr 6, priced at $223 found 9 hours ago
Frontier Airlines
Fri, Mar 13 - Thu, Mar 19
TTN
Mercer
DSM
Des Moines Intl.
$234 Roundtrip, found 6 days ago
$234
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Fri, Mar 13 from Mercer to Des Moines Intl., returning Thu, Mar 19, priced at $234 found 6 days ago
Bargain Flight
Sat, Mar 14 - Sat, Mar 28
BNA
Nashville Intl.
DSM
Des Moines Intl.
$239 Roundtrip, found 3 hours ago
$239
Roundtrip
found 3 hours ago
Select Bargain Flight flight, departing Sat, Mar 14 from Nashville Intl. to Des Moines Intl., returning Sat, Mar 28, priced at $239 found 3 hours ago
Frontier Airlines
Fri, Feb 27 - Sat, Mar 7
SMF
Sacramento Intl.
DSM
Des Moines Intl.
$255 Roundtrip, found 4 days ago
$255
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Fri, Feb 27 from Sacramento Intl. to Des Moines Intl., returning Sat, Mar 7, priced at $255 found 4 days ago
Frontier Airlines
Thu, Feb 26 - Sat, Mar 7
BOI
Boise
DSM
Des Moines Intl.
$260 Roundtrip, found 14 hours ago
$260
Roundtrip
found 14 hours ago
Select Frontier Airlines flight, departing Thu, Feb 26 from Boise to Des Moines Intl., returning Sat, Mar 7, priced at $260 found 14 hours ago
Frontier Airlines
Mon, Feb 23 - Tue, Mar 10
ATL
Hartsfield-Jackson Atlanta Intl.
DSM
Des Moines Intl.
$260 Roundtrip, found 1 day ago
$260
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Feb 23 from Hartsfield-Jackson Atlanta Intl. to Des Moines Intl., returning Tue, Mar 10, priced at $260 found 1 day ago
American Airlines
Tue, Apr 28 - Tue, May 5
COS
Colorado Springs
DSM
Des Moines Intl.
$263 Roundtrip, found 8 hours ago
$263
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Tue, Apr 28 from Colorado Springs to Des Moines Intl., returning Tue, May 5, priced at $263 found 8 hours ago
Delta
Tue, Jul 28 - Sat, Aug 8
EWR
Newark Liberty Intl. Airport
DSM
Des Moines Intl.
$279 Roundtrip, found 1 hour ago
$279
Roundtrip
found 1 hour ago
Select Delta flight, departing Tue, Jul 28 from Newark Liberty Intl. Airport to Des Moines Intl., returning Sat, Aug 8, priced at $279 found 1 hour ago
Delta
Wed, Aug 5 - Sat, Aug 15
LGA
LaGuardia
DSM
Des Moines Intl.
$351 Roundtrip, found 4 hours ago
$351
Roundtrip
found 4 hours ago
Select Delta flight, departing Wed, Aug 5 from LaGuardia to Des Moines Intl., returning Sat, Aug 15, priced at $351 found 4 hours ago

Cheap Flights to De Soto

Fall in love at first flight with your vacation to De Soto by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to De Soto on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in De Soto, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to De Soto

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to De Soto with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to De Soto?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to De Soto are in March, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to De Soto?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to De Soto.

What airport is best to fly into De Soto?

When you’re planning your trip to De Soto, convenience is the name of the game. Luckily, De Soto Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your De Soto must-do list.

How much are flights to De Soto?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to De Soto on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $58, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to De Soto?

The trick to saving a stack of cash on your flight to De Soto? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $58 right now, why wait?

De Soto Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$58

Last Minute Hotel Deals in De Soto

Edgetowner Motel

Edgetowner Motel

2.5 out of 5
804 Guthrie St De Soto IA
Book a stay at this business-friendly motel in De Soto. Enjoy free parking, a business center, and a garden. Popular attractions Van Meter Recreation Complex ...
6.2/10 (161 reviews)
This was a good, older, inexpensive motel - clean and all the stuff works properly.

Reviewed on Feb 19, 2026

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Edgetowner Motel
Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd Urbandale IA
Book a stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.6/10 (725 reviews)
For

Reviewed on Feb 17, 2026

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Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Sonesta Simply Suites Des Moines

Sonesta Simply Suites Des Moines

2 out of 5
7625 Office Plaza Dr N West Des Moines IA
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful ...
8.4/10 Very Good! (984 reviews)
Hotel was accomodating and welcoming...3 or 4 staff changes and still courteous. Definitely will be staying there again in the future!!

Reviewed on Feb 19, 2026

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Sonesta Simply Suites Des Moines
Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

2.5 out of 5
5291 Stoney Creek Court Johnston IA
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (1,837 reviews)
Water poured from the light fixture in the bathroom. Room above us was having bath tub draining issues. The rest of the hotel is outdated and falling apart. The pictures on line are 20+ years old. I don’t recommend but our room was clean for the most part.

Reviewed on Feb 16, 2026

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Stoney Creek Hotel Des Moines - Johnston
Hyatt Place West Des Moines Jordan Creek

Hyatt Place West Des Moines Jordan Creek

3 out of 5
295 South 64th st West Des Moines IA
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,002 reviews)
Room was very nice. The size was larger than I anticipated. However, if you think you might have a nice breakfast, think again. The hotel was sold out Saturday evening with basketball teams. Sunday breakfast was from7a-10a. They did not have enough food for all of the guests. At 9a when we went down, ...

Reviewed on Feb 18, 2026

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Hyatt Place West Des Moines Jordan Creek
Drury Inn & Suites West Des Moines

Drury Inn & Suites West Des Moines

3 out of 5
5505 Mills Civic Pkwy West Des Moines IA
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,002 reviews)
Clean rooms, happy hour from 5:30-7 where every day you received three free alcoholic drinks and "snacks" that were equivalent to a meal. Free breakfast with that and I didn't spend any money on dinner for my entire stay.

Reviewed on Feb 19, 2026

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Drury Inn & Suites West Des Moines
Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,228 reviews)
Jenn was amazing!!! She was so easy to talk yo and answer all my questions. The hot tub was perfect- hot & it bubbled!! I have had a hard time finding hotels with the hot tubs that jets work and are actually hot and not pool temps! Breakfast was good variety of food as well. Pretty wuiet hotel and ...

Reviewed on Feb 17, 2026

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Wildwood Lodge
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,759 reviews)
Excellent hotel near airport. Convenient shuttle service. And breakfast is served as early as 4:30am. Room is not so big but clean and ample space is provided for large and small roller suitcases. And price is a bonus. Highly recommended!

Reviewed on Feb 19, 2026

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Days Inn & Suites by Wyndham Des Moines Airport
See all 423 properties in De Soto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.