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De Soto

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De Soto Flights as Low as $152

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, Aug 12 - Mon, Aug 17
DEN
Denver Intl.
DSM
Des Moines Intl.
$152 Roundtrip, found 6 hours ago
$152
Roundtrip
found 6 hours ago
Select Frontier Airlines flight, departing Wed, Aug 12 from Denver Intl. to Des Moines Intl., returning Mon, Aug 17, priced at $152 found 6 hours ago
Frontier Airlines
Wed, Aug 5 - Wed, Aug 12
IAH
George Bush Intercontinental
DSM
Des Moines Intl.
$215 Roundtrip, found 6 hours ago
$215
Roundtrip
found 6 hours ago
Select Frontier Airlines flight, departing Wed, Aug 5 from George Bush Intercontinental to Des Moines Intl., returning Wed, Aug 12, priced at $215 found 6 hours ago
United
Tue, Aug 18 - Tue, Aug 25
DEN
Denver Intl.
DSM
Des Moines Intl.
$227 Roundtrip, found 6 hours ago
$227
Roundtrip
found 6 hours ago
Select United flight, departing Tue, Aug 18 from Denver Intl. to Des Moines Intl., returning Tue, Aug 25, priced at $227 found 6 hours ago
Frontier Airlines
Tue, Jul 21 - Wed, Aug 5
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$236 Roundtrip, found 4 days ago
$236
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Tue, Jul 21 from Sky Harbor Intl. to Des Moines Intl., returning Wed, Aug 5, priced at $236 found 4 days ago
Bargain Flight
Tue, Jul 7 - Thu, Jul 9
PIT
Pittsburgh Intl.
DSM
Des Moines Intl.
$246 Roundtrip, found 6 days ago
$246
Roundtrip
found 6 days ago
Select Bargain Flight flight, departing Tue, Jul 7 from Pittsburgh Intl. to Des Moines Intl., returning Thu, Jul 9, priced at $246 found 6 days ago
Delta
Tue, Aug 18 - Tue, Aug 25
DEN
Denver Intl.
DSM
Des Moines Intl.
$247 Roundtrip, found 6 hours ago
$247
Roundtrip
found 6 hours ago
Select Delta flight, departing Tue, Aug 18 from Denver Intl. to Des Moines Intl., returning Tue, Aug 25, priced at $247 found 6 hours ago
American Airlines
Tue, Aug 18 - Tue, Aug 25
DEN
Denver Intl.
DSM
Des Moines Intl.
$247 Roundtrip, found 6 hours ago
$247
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Tue, Aug 18 from Denver Intl. to Des Moines Intl., returning Tue, Aug 25, priced at $247 found 6 hours ago
Bargain Flight
Tue, Jul 21 - Wed, Jul 29
SAT
San Antonio Intl.
DSM
Des Moines Intl.
$275 Roundtrip, found 6 hours ago
$275
Roundtrip
found 6 hours ago
Select Bargain Flight flight, departing Tue, Jul 21 from San Antonio Intl. to Des Moines Intl., returning Wed, Jul 29, priced at $275 found 6 hours ago
Bargain Flight
Tue, Nov 17 - Fri, Nov 20
JAX
Jacksonville Intl.
DSM
Des Moines Intl.
$277 Roundtrip, found 6 hours ago
$277
Roundtrip
found 6 hours ago
Select Bargain Flight flight, departing Tue, Nov 17 from Jacksonville Intl. to Des Moines Intl., returning Fri, Nov 20, priced at $277 found 6 hours ago
Bargain Flight
Tue, Jul 28 - Tue, Aug 4
LAX
Los Angeles Intl.
DSM
Des Moines Intl.
$280 Roundtrip, found 22 hours ago
$280
Roundtrip
found 22 hours ago
Select Bargain Flight flight, departing Tue, Jul 28 from Los Angeles Intl. to Des Moines Intl., returning Tue, Aug 4, priced at $280 found 22 hours ago
Frontier Airlines
Sun, Aug 2 - Mon, Aug 10
TPA
Tampa Intl.
DSM
Des Moines Intl.
$290 Roundtrip, found 1 day ago
$290
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Aug 2 from Tampa Intl. to Des Moines Intl., returning Mon, Aug 10, priced at $290 found 1 day ago
American Airlines
Wed, Jul 8 - Sat, Jul 11
EWR
Newark Liberty Intl. Airport
DSM
Des Moines Intl.
$326 Roundtrip, found 6 days ago
$326
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Jul 8 from Newark Liberty Intl. Airport to Des Moines Intl., returning Sat, Jul 11, priced at $326 found 6 days ago
Bargain Flight
Wed, Jul 8 - Sat, Jul 11
LGA
LaGuardia
DSM
Des Moines Intl.
$349 Roundtrip, found 6 hours ago
$349
Roundtrip
found 6 hours ago
Select Bargain Flight flight, departing Wed, Jul 8 from LaGuardia to Des Moines Intl., returning Sat, Jul 11, priced at $349 found 6 hours ago
American Airlines
Tue, Jul 28 - Wed, Aug 5
FLL
Fort Lauderdale - Hollywood Intl.
DSM
Des Moines Intl.
$355 Roundtrip, found 6 hours ago
$355
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Tue, Jul 28 from Fort Lauderdale - Hollywood Intl. to Des Moines Intl., returning Wed, Aug 5, priced at $355 found 6 hours ago
Delta
Sun, Jul 12 - Tue, Jul 14
SAV
Savannah - Hilton Head Intl.
DSM
Des Moines Intl.
$380 Roundtrip, found 8 hours ago
$380
Roundtrip
found 8 hours ago
Select Delta flight, departing Sun, Jul 12 from Savannah - Hilton Head Intl. to Des Moines Intl., returning Tue, Jul 14, priced at $380 found 8 hours ago
Frontier Airlines
Tue, Jun 23 - Fri, Jun 26
ORD
O'Hare Intl.
DSM
Des Moines Intl.
$404 Roundtrip, found 1 day ago
$404
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Tue, Jun 23 from O'Hare Intl. to Des Moines Intl., returning Fri, Jun 26, priced at $404 found 1 day ago

Cheap Flights to De Soto

Fall in love at first flight with your vacation to De Soto by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to De Soto on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in De Soto, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to De Soto

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to De Soto with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to De Soto?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to De Soto are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to De Soto?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 11 to choose from for your flight to De Soto.

What airport is best to fly into De Soto?

When you’re planning your trip to De Soto, convenience is the name of the game. Luckily, De Soto Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your De Soto must-do list.

How much are flights to De Soto?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to De Soto on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $152, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to De Soto?

The trick to saving a stack of cash on your flight to De Soto? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $152 right now, why wait?

De Soto Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$151

Last Minute Hotel Deals in De Soto

Edgetowner Motel

Edgetowner Motel

2.5 out of 5
804 Guthrie St De Soto IA
Book a stay at this business-friendly motel in De Soto. Enjoy free parking, a business center, and a garden. Popular attractions Van Meter Recreation Complex ...
6.2/10 (165 reviews)
"The sheets were clean but not much else. Bathroom was full of mold, faucets installed backwards, rough towels, cracked and peeling cabinets."

Reviewed on Jun 5, 2026

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Edgetowner Motel
Fairfield Inn and Suites by Marriott Des Moines West

Fairfield Inn and Suites by Marriott Des Moines West

3 out of 5
7225 Vista Dr West Des Moines IA
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,003 reviews)
"The staff were very polite and helpful. The rooms were clean and well maintained."

Reviewed on Jun 19, 2026

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Fairfield Inn and Suites by Marriott Des Moines West
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,812 reviews)
"Things were generally clean but room showed some aging. Toilet flushing wasn't the greatest but we made it work. Sink handle seemed like it could use some lubrication. Hotel generally ok."

Reviewed on Jun 20, 2026

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Days Inn & Suites by Wyndham Des Moines Airport
Drury Inn & Suites West Des Moines

Drury Inn & Suites West Des Moines

3 out of 5
5505 Mills Civic Pkwy West Des Moines IA
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,062 reviews)
"Elevator was broken lots of people trying to use 1 elevator"

Reviewed on Jun 20, 2026

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Drury Inn & Suites West Des Moines
Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

2.5 out of 5
5291 Stoney Creek Court Johnston IA
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (1,852 reviews)
"They have been renovating and things are kind of a mess. Pool being worked on. 2nd floor under renovation. 1st floor still needs done. Only 3rd floor done. No wash cloths in our room the first night. No hot water 2nd day in the afternoon. Had to take a cold shower. One of these things is no big deal ..."

Reviewed on Jun 20, 2026

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Stoney Creek Hotel Des Moines - Johnston
Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N West Des Moines IA
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
7.8/10 Good! (913 reviews)
"Staff was kind an friendly Cons other guests are rude an disrespectful I have so many door dings on my vehicle now but not property's fault they cant control their customers some people just dont have respect nor manners But property's other then that was quiet an relaxing"

Reviewed on Jun 15, 2026

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Motel 6 West Des Moines, IA
Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,232 reviews)
"Front desk staff was amazing. The place was spotless and the price was awesome for how nice it was. We were riding back from Sturgis heading back home to Cincinnati and just needed a place to sleep for the night. This place is awesome. If I’m ever back in that area I’ll 100% stay there again."

Reviewed on Jun 20, 2026

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Wildwood Lodge
Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd Urbandale IA
Book a stay at this family-friendly hotel in Urbandale. Enjoy free WiFi, free parking, and a water park. Our guests praise the helpful staff and the clean rooms ...
5.8/10 (877 reviews)
"The Waterpark is pretty good and oie kids had fun. The rooms smell and are not the greatest. Beds were decent and we slept well. The price is inexpensive...and the Waterpark being included was great. But if I would have known the state of the rooms I would have made reservations elsewhere."

Reviewed on Jun 19, 2026

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Ramada Tropics Resort & Conf Center by Wyndham Des Moines
See all 424 properties in De Soto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.