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De Soto

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De Soto Flights as Low as $130

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Fri, Aug 22 - Sun, Aug 24
DEN
Denver Intl.
DSM
Des Moines Intl.
$130 Roundtrip, found 1 day ago
$130
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Aug 22 from Denver Intl. to Des Moines Intl., returning Sun, Aug 24, priced at $130 found 1 day ago
Bargain Flight
Sat, Sep 13 - Sat, Sep 20
SDF
Louisville Intl.
DSM
Des Moines Intl.
$185 Roundtrip, found 1 day ago
$185
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Sat, Sep 13 from Louisville Intl. to Des Moines Intl., returning Sat, Sep 20, priced at $185 found 1 day ago
American Airlines
Tue, Jul 29 - Sun, Aug 3
ORD
O'Hare Intl.
DSM
Des Moines Intl.
$203 Roundtrip, found 1 day ago
$203
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jul 29 from O'Hare Intl. to Des Moines Intl., returning Sun, Aug 3, priced at $203 found 1 day ago
Bargain Flight
Tue, Aug 12 - Tue, Aug 19
BUF
Buffalo Niagara Intl.
DSM
Des Moines Intl.
$210 Roundtrip, found 1 day ago
$210
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Tue, Aug 12 from Buffalo Niagara Intl. to Des Moines Intl., returning Tue, Aug 19, priced at $210 found 1 day ago
Bargain Flight
Sat, Aug 9 - Wed, Aug 13
DFW
Dallas-Fort Worth Intl.
DSM
Des Moines Intl.
$233 Roundtrip, found 3 days ago
$233
Roundtrip
found 3 days ago
Select Bargain Flight flight, departing Sat, Aug 9 from Dallas-Fort Worth Intl. to Des Moines Intl., returning Wed, Aug 13, priced at $233 found 3 days ago
Bargain Flight
Thu, Sep 11 - Wed, Sep 17
CLT
Charlotte-Douglas Intl.
DSM
Des Moines Intl.
$235 Roundtrip, found 19 hours ago
$235
Roundtrip
found 19 hours ago
Select Bargain Flight flight, departing Thu, Sep 11 from Charlotte-Douglas Intl. to Des Moines Intl., returning Wed, Sep 17, priced at $235 found 19 hours ago
American Airlines
Tue, Nov 4 - Tue, Nov 11
VPS
Northwest Florida Regional
DSM
Des Moines Intl.
$235 Roundtrip, found 20 hours ago
$235
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Tue, Nov 4 from Northwest Florida Regional to Des Moines Intl., returning Tue, Nov 11, priced at $235 found 20 hours ago
Delta
Wed, Aug 13 - Tue, Aug 19
ECP
Northwest Florida Beaches Intl.
DSM
Des Moines Intl.
$237 Roundtrip, found 1 day ago
$237
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Aug 13 from Northwest Florida Beaches Intl. to Des Moines Intl., returning Tue, Aug 19, priced at $237 found 1 day ago
Bargain Flight
Wed, Aug 20 - Mon, Aug 25
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$242 Roundtrip, found 1 day ago
$242
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Wed, Aug 20 from Sky Harbor Intl. to Des Moines Intl., returning Mon, Aug 25, priced at $242 found 1 day ago
United
Thu, Aug 28 - Thu, Sep 11
FNT
Bishop Intl.
DSM
Des Moines Intl.
$252 Roundtrip, found 1 day ago
$252
Roundtrip
found 1 day ago
Select United flight, departing Thu, Aug 28 from Bishop Intl. to Des Moines Intl., returning Thu, Sep 11, priced at $252 found 1 day ago
Bargain Flight
Sat, Sep 6 - Sat, Sep 13
LAX
Los Angeles Intl.
DSM
Des Moines Intl.
$254 Roundtrip, found 23 hours ago
$254
Roundtrip
found 23 hours ago
Select Bargain Flight flight, departing Sat, Sep 6 from Los Angeles Intl. to Des Moines Intl., returning Sat, Sep 13, priced at $254 found 23 hours ago
Bargain Flight
Sat, Oct 18 - Tue, Oct 21
BOI
Boise
DSM
Des Moines Intl.
$255 Roundtrip, found 1 day ago
$255
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Sat, Oct 18 from Boise to Des Moines Intl., returning Tue, Oct 21, priced at $255 found 1 day ago
United
Fri, Jul 25 - Sun, Aug 3
IAH
George Bush Intercontinental
DSM
Des Moines Intl.
$268 Roundtrip, found 6 days ago
$268
Roundtrip
found 6 days ago
Select United flight, departing Fri, Jul 25 from George Bush Intercontinental to Des Moines Intl., returning Sun, Aug 3, priced at $268 found 6 days ago
Bargain Flight
Tue, Jul 22 - Tue, Jul 29
BOS
Logan Intl.
DSM
Des Moines Intl.
$286 Roundtrip, found 1 day ago
$286
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Tue, Jul 22 from Logan Intl. to Des Moines Intl., returning Tue, Jul 29, priced at $286 found 1 day ago
Frontier Airlines
Mon, Sep 15 - Mon, Sep 22
SEA
Seattle - Tacoma Intl.
DSM
Des Moines Intl.
$294 Roundtrip, found 1 day ago
$294
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Sep 15 from Seattle - Tacoma Intl. to Des Moines Intl., returning Mon, Sep 22, priced at $294 found 1 day ago
Delta
Wed, Aug 20 - Sat, Aug 23
TUS
Tucson Intl.
DSM
Des Moines Intl.
$303 Roundtrip, found 3 days ago
$303
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Aug 20 from Tucson Intl. to Des Moines Intl., returning Sat, Aug 23, priced at $303 found 3 days ago

Cheap Flights to De Soto

Fall in love at first flight with your vacation to De Soto by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to De Soto on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in De Soto, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to De Soto

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to De Soto with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to De Soto?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to De Soto are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to De Soto?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 8 to choose from for your flight to De Soto.

What airport is best to fly into De Soto?

When you’re planning your trip to De Soto, convenience is the name of the game. Luckily, De Soto Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your De Soto must-do list.

How much are flights to De Soto?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to De Soto on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $130, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to De Soto?

The trick to saving a stack of cash on your flight to De Soto? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $130 right now, why wait?

De Soto Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$130

Last Minute Hotel Deals in De Soto

Edgetowner Motel

Edgetowner Motel

2.5 out of 5
804 Guthrie St, De Soto, IA
Book a stay at this business-friendly motel in De Soto. Enjoy free parking, a business center, and a garden. Popular attractions Van Meter Recreation Complex ...
6/10 (139 reviews)
"Its what i was looking for"

Reviewed on Apr 21, 2025

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Edgetowner Motel
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave, Des Moines, IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,548 reviews)
"I liked the fact that it wasn’t the most expensive hotel room on the planet but it wasn’t great either. It was just so so. It poured for the entire first night and what do you know I couldn’t get a single tv channel to come in, not a one. It just said signal loss. Oh well, thank goodness for cell ..."

Reviewed on Jul 14, 2025

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Days Inn & Suites by Wyndham Des Moines Airport
Days Inn by Wyndham West Des Moines / Clive

Days Inn by Wyndham West Des Moines / Clive

2 out of 5
1600 NW 114th St, Clive, IA
Book a stay at this business-friendly hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Jordan Creek Town Center and Clive ...
6/10 (1,004 reviews)
"My response is the same as the page response."

Reviewed on Jul 8, 2025

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Days Inn by Wyndham West Des Moines / Clive
Sonesta Essential Des Moines

Sonesta Essential Des Moines

2 out of 5
4755 Merle Hay Road, Des Moines, IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.2/10 Good! (1,015 reviews)
"Booked as pet friendly and then they charged a fee on arrival for the pet. Otherwise great stay. They do give you a dog bowl and treats for your pet"

Reviewed on Jul 11, 2025

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Sonesta Essential Des Moines
Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N, West Des Moines, IA
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
7.8/10 Good! (442 reviews)
"It was nice to walk into a nice and cool room"

Reviewed on Jul 13, 2025

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Motel 6 West Des Moines, IA
Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

2.5 out of 5
5291 Stoney Creek Court, Johnston, IA
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (1,747 reviews)
"Very cute! Hidden gem!"

Reviewed on Jul 14, 2025

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Stoney Creek Hotel Des Moines - Johnston
Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave, Clive, IA
Stay at this 3-star hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,216 reviews)
"All good"

Reviewed on Jul 14, 2025

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Wildwood Lodge
Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd, Urbandale, IA
Book a stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.6/10 (500 reviews)
"The only issue I had was with the slides. The rules on what life jacket to wear wasn’t posted anywhere. My son went down one slide with a life jacket and the second time was told he couldn’t wear that one. He had to wear one that buckled in the back not in the front. The rules weren’t posted on the ..."

Reviewed on Jul 12, 2025

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Ramada Tropics Resort & Conf Center by Wyndham Des Moines
See all 387 properties in De Soto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.