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De Soto

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De Soto Flights as Low as $148

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Mon, Aug 18 - Thu, Aug 21
DEN
Denver Intl.
DSM
Des Moines Intl.
$148 Roundtrip, found 1 day ago
$148
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Aug 18 from Denver Intl. to Des Moines Intl., returning Thu, Aug 21, priced at $148 found 1 day ago
United
Fri, Aug 1 - Mon, Aug 4
ORD
O'Hare Intl.
DSM
Des Moines Intl.
$189 Roundtrip, just found
$189
Roundtrip
just found
Select United flight, departing Fri, Aug 1 from O'Hare Intl. to Des Moines Intl., returning Mon, Aug 4, priced at $189 just found
American Airlines
Tue, Jul 29 - Wed, Jul 30
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$189 Roundtrip, found 18 hours ago
$189
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Tue, Jul 29 from Sky Harbor Intl. to Des Moines Intl., returning Wed, Jul 30, priced at $189 found 18 hours ago
Bargain Flight
Thu, Jun 12 - Sun, Jun 15
CVG
Cincinnati - Northern Kentucky Intl.
DSM
Des Moines Intl.
$231 Roundtrip, found 1 day ago
$231
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Thu, Jun 12 from Cincinnati - Northern Kentucky Intl. to Des Moines Intl., returning Sun, Jun 15, priced at $231 found 1 day ago
United
Tue, Jun 17 - Tue, Jun 24
IAH
George Bush Intercontinental
DSM
Des Moines Intl.
$234 Roundtrip, just found
$234
Roundtrip
just found
Select United flight, departing Tue, Jun 17 from George Bush Intercontinental to Des Moines Intl., returning Tue, Jun 24, priced at $234 just found
Frontier Airlines
Mon, Jun 9 - Mon, Jun 16
DFW
Dallas-Fort Worth Intl.
DSM
Des Moines Intl.
$245 Roundtrip, found 2 days ago
$245
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Mon, Jun 9 from Dallas-Fort Worth Intl. to Des Moines Intl., returning Mon, Jun 16, priced at $245 found 2 days ago
Delta
Tue, Jul 1 - Fri, Jul 4
SDF
Louisville Intl.
DSM
Des Moines Intl.
$252 Roundtrip, found 17 hours ago
$252
Roundtrip
found 17 hours ago
Select Delta flight, departing Tue, Jul 1 from Louisville Intl. to Des Moines Intl., returning Fri, Jul 4, priced at $252 found 17 hours ago
Frontier Airlines
Fri, Jun 20 - Mon, Jun 30
SNA
John Wayne
DSM
Des Moines Intl.
$254 Roundtrip, found 1 day ago
$254
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Jun 20 from John Wayne to Des Moines Intl., returning Mon, Jun 30, priced at $254 found 1 day ago
Bargain Flight
Thu, Jun 5 - Mon, Jun 9
CMH
John Glenn Columbus Intl.
DSM
Des Moines Intl.
$258 Roundtrip, found 14 hours ago
$258
Roundtrip
found 14 hours ago
Select Bargain Flight flight, departing Thu, Jun 5 from John Glenn Columbus Intl. to Des Moines Intl., returning Mon, Jun 9, priced at $258 found 14 hours ago
Delta
Thu, Jun 19 - Tue, Jun 24
EWR
Newark Liberty Intl. Airport
DSM
Des Moines Intl.
$259 Roundtrip, found 1 day ago
$259
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Jun 19 from Newark Liberty Intl. Airport to Des Moines Intl., returning Tue, Jun 24, priced at $259 found 1 day ago
Bargain Flight
Wed, Jul 9 - Tue, Jul 15
DCA
Ronald Reagan Washington National
DSM
Des Moines Intl.
$263 Roundtrip, found 1 day ago
$263
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Wed, Jul 9 from Ronald Reagan Washington National to Des Moines Intl., returning Tue, Jul 15, priced at $263 found 1 day ago
Bargain Flight
Wed, Jul 23 - Tue, Jul 29
TPA
Tampa Intl.
DSM
Des Moines Intl.
$264 Roundtrip, found 15 hours ago
$264
Roundtrip
found 15 hours ago
Select Bargain Flight flight, departing Wed, Jul 23 from Tampa Intl. to Des Moines Intl., returning Tue, Jul 29, priced at $264 found 15 hours ago
Delta
Tue, Jul 22 - Tue, Jul 29
IAD
Washington Dulles Intl.
DSM
Des Moines Intl.
$277 Roundtrip, found 6 days ago
$277
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Jul 22 from Washington Dulles Intl. to Des Moines Intl., returning Tue, Jul 29, priced at $277 found 6 days ago
Delta
Wed, Jun 25 - Tue, Jul 1
LGA
LaGuardia
DSM
Des Moines Intl.
$300 Roundtrip, found 1 day ago
$300
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Jun 25 from LaGuardia to Des Moines Intl., returning Tue, Jul 1, priced at $300 found 1 day ago
Bargain Flight
Wed, Sep 17 - Tue, Sep 30
SLC
Salt Lake City Intl.
DSM
Des Moines Intl.
$302 Roundtrip, found 4 hours ago
$302
Roundtrip
found 4 hours ago
Select Bargain Flight flight, departing Wed, Sep 17 from Salt Lake City Intl. to Des Moines Intl., returning Tue, Sep 30, priced at $302 found 4 hours ago
American Airlines
Wed, Jul 9 - Wed, Jul 16
CLD
McClellan-Palomar
DSM
Des Moines Intl.
$309 Roundtrip, found 6 days ago
$309
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Jul 9 from McClellan-Palomar to Des Moines Intl., returning Wed, Jul 16, priced at $309 found 6 days ago

Cheap Flights to De Soto

Fall in love at first flight with your vacation to De Soto by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to De Soto on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in De Soto, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to De Soto

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to De Soto with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to De Soto?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to De Soto are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to De Soto?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 11 to choose from for your flight to De Soto.

What airport is best to fly into De Soto?

When you’re planning your trip to De Soto, convenience is the name of the game. Luckily, De Soto Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your De Soto must-do list.

How much are flights to De Soto?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to De Soto on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $148, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to De Soto?

The trick to saving a stack of cash on your flight to De Soto? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $148 right now, why wait?

De Soto Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$148

Last Minute Hotel Deals in De Soto

Edgetowner Motel
Edgetowner Motel
2.5 out of 5
804 Guthrie St, De Soto, IA
Book a stay at this business-friendly motel in De Soto. Enjoy free parking, a business center, and a garden. Popular attractions Van Meter Recreation Complex ...
6/10 (135 reviews)
"Its what i was looking for"

Reviewed on Apr 21, 2025

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Edgetowner Motel
Stoney Creek Hotel Des Moines - Johnston
Stoney Creek Hotel Des Moines - Johnston
2.5 out of 5
5291 Stoney Creek Court, Johnston, IA
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (1,700 reviews)
"Very nice, cute little hotel"

Reviewed on May 26, 2025

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Stoney Creek Hotel Des Moines - Johnston
Days Inn & Suites by Wyndham Des Moines Airport
Days Inn & Suites by Wyndham Des Moines Airport
2 out of 5
1901 Hackley Ave, Des Moines, IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,492 reviews)
"Staff was nice, but the place was really noisy which made it hard to sleep"

Reviewed on May 26, 2025

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Days Inn & Suites by Wyndham Des Moines Airport
Sonesta Essential Des Moines
Sonesta Essential Des Moines
2 out of 5
4755 Merle Hay Road, Des Moines, IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.2/10 Good! (1,007 reviews)
"Normally I stay downtown or higher end hotels but I had a good time at the hotel. My room was right next to parking spot and I got good deal thru online booking. Nice updates. Breakfast could have been more options and wish the gym was available but I found one down the street from where I was."

Reviewed on May 27, 2025

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Sonesta Essential Des Moines
Motel 6 West Des Moines, IA
Motel 6 West Des Moines, IA
2 out of 5
7655 Office Plaza Dr N, West Des Moines, IA
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (342 reviews)
"Clean - the most important aspect of a hotel. It’s an older building and you can tell but it’s clean and didn’t have any bad smells. Which for the price point, is more than what you would expect from other properties at the same price point. Service was good, efficient check-in. Would stay ..."

Reviewed on May 26, 2025

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Motel 6 West Des Moines, IA
Fairfield Inn and Suites by Marriott Des Moines West
Fairfield Inn and Suites by Marriott Des Moines West
2.5 out of 5
7225 Vista Dr, West Des Moines, IA
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,007 reviews)
"I would stay there again."

Reviewed on May 28, 2025

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Fairfield Inn and Suites by Marriott Des Moines West
Quality Inn & Suites Des Moines - Merle Hay Road
Quality Inn & Suites Des Moines - Merle Hay Road
2.5 out of 5
4995 Merle Hay Rd, Des Moines, IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (885 reviews)
"I was comfortable enough to get a goodnight sleep,and the room location with parking was very convenient"

Reviewed on May 21, 2025

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Quality Inn & Suites Des Moines - Merle Hay Road
La Quinta Inn & Suites by Wyndham Des Moines West Clive
La Quinta Inn & Suites by Wyndham Des Moines West Clive
3 out of 5
1390 Nw 118th St, Clive, IA
Stay at this 3-star family-friendly hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,003 reviews)
Nice place to stay, small bathroom
"The room was very nice, the only down side about the stay was how small the bathroom was and there was no place to put items besides sitting them on the toilet"

Reviewed on May 20, 2025

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La Quinta Inn & Suites by Wyndham Des Moines West Clive
See all 370 properties in De Soto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.