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De Soto

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De Soto Flights as Low as $191

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, Apr 23 - Wed, Apr 30
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$191 Roundtrip, found 22 hours ago
$191
Roundtrip
found 22 hours ago
Select Frontier Airlines flight, departing Wed, Apr 23 from Sky Harbor Intl. to Des Moines Intl., returning Wed, Apr 30, priced at $191 found 22 hours ago
Frontier Airlines
Mon, Apr 21 - Wed, Apr 23
DCA
Ronald Reagan Washington National
DSM
Des Moines Intl.
$200 Roundtrip, found 21 hours ago
$200
Roundtrip
found 21 hours ago
Select Frontier Airlines flight, departing Mon, Apr 21 from Ronald Reagan Washington National to Des Moines Intl., returning Wed, Apr 23, priced at $200 found 21 hours ago
American Airlines
Tue, Jun 10 - Tue, Jul 8
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$203 Roundtrip, found 4 days ago
$203
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Jun 10 from Sky Harbor Intl. to Des Moines Intl., returning Tue, Jul 8, priced at $203 found 4 days ago
Bargain Flight
Tue, May 13 - Tue, May 20
COS
Colorado Springs
DSM
Des Moines Intl.
$203 Roundtrip, found 21 hours ago
$203
Roundtrip
found 21 hours ago
Select Bargain Flight flight, departing Tue, May 13 from Colorado Springs to Des Moines Intl., returning Tue, May 20, priced at $203 found 21 hours ago
Delta
Tue, Jul 1 - Wed, Jul 2
COS
Colorado Springs
DSM
Des Moines Intl.
$217 Roundtrip, found 22 hours ago
$217
Roundtrip
found 22 hours ago
Select Delta flight, departing Tue, Jul 1 from Colorado Springs to Des Moines Intl., returning Wed, Jul 2, priced at $217 found 22 hours ago
Frontier Airlines
Mon, May 12 - Wed, May 21
SAN
San Diego Intl.
DSM
Des Moines Intl.
$222 Roundtrip, found 20 hours ago
$222
Roundtrip
found 20 hours ago
Select Frontier Airlines flight, departing Mon, May 12 from San Diego Intl. to Des Moines Intl., returning Wed, May 21, priced at $222 found 20 hours ago
Frontier Airlines
Sun, Apr 20 - Wed, Apr 23
DFW
Dallas-Fort Worth Intl.
DSM
Des Moines Intl.
$243 Roundtrip, found 19 hours ago
$243
Roundtrip
found 19 hours ago
Select Frontier Airlines flight, departing Sun, Apr 20 from Dallas-Fort Worth Intl. to Des Moines Intl., returning Wed, Apr 23, priced at $243 found 19 hours ago
Delta
Wed, Jun 11 - Wed, Jun 18
IAD
Washington Dulles Intl.
DSM
Des Moines Intl.
$271 Roundtrip, found 22 hours ago
$271
Roundtrip
found 22 hours ago
Select Delta flight, departing Wed, Jun 11 from Washington Dulles Intl. to Des Moines Intl., returning Wed, Jun 18, priced at $271 found 22 hours ago
Delta
Wed, May 14 - Tue, May 20
CLT
Charlotte-Douglas Intl.
DSM
Des Moines Intl.
$271 Roundtrip, found 6 days ago
$271
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, May 14 from Charlotte-Douglas Intl. to Des Moines Intl., returning Tue, May 20, priced at $271 found 6 days ago
Delta
Wed, May 14 - Wed, May 14
YUL
Pierre Elliott Trudeau Intl.
DSM
Des Moines Intl.
$289 Roundtrip, found 1 day ago
$289
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, May 14 from Pierre Elliott Trudeau Intl. to Des Moines Intl., returning Wed, May 14, priced at $289 found 1 day ago
American Airlines
Thu, May 15 - Sun, May 18
CLD
McClellan-Palomar
DSM
Des Moines Intl.
$291 Roundtrip, found 20 hours ago
$291
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Thu, May 15 from McClellan-Palomar to Des Moines Intl., returning Sun, May 18, priced at $291 found 20 hours ago
Delta
Fri, May 16 - Tue, May 20
ELM
Elmira - Corning Regional
DSM
Des Moines Intl.
$456 Roundtrip, found 19 hours ago
$456
Roundtrip
found 19 hours ago
Select Delta flight, departing Fri, May 16 from Elmira - Corning Regional to Des Moines Intl., returning Tue, May 20, priced at $456 found 19 hours ago
Delta
Fri, Apr 18 - Sun, Apr 20
DAL
Love Field
DSM
Des Moines Intl.
$497 Roundtrip, found 19 hours ago
$497
Roundtrip
found 19 hours ago
Select Delta flight, departing Fri, Apr 18 from Love Field to Des Moines Intl., returning Sun, Apr 20, priced at $497 found 19 hours ago
United
Tue, Jun 24 - Wed, Jul 9
CZM
Cozumel Intl.
DSM
Des Moines Intl.
$504 Roundtrip, found 22 hours ago
$504
Roundtrip
found 22 hours ago
Select United flight, departing Tue, Jun 24 from Cozumel Intl. to Des Moines Intl., returning Wed, Jul 9, priced at $504 found 22 hours ago
American Airlines
Mon, May 5 - Sat, May 17
YQB
Jean Lesage Intl.
DSM
Des Moines Intl.
$557 Roundtrip, found 21 hours ago
$557
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Mon, May 5 from Jean Lesage Intl. to Des Moines Intl., returning Sat, May 17, priced at $557 found 21 hours ago
United
Wed, Jun 11 - Wed, Jun 25
MLM
General Francisco Mujica Intl.
DSM
Des Moines Intl.
$612 Roundtrip, found 19 hours ago
$612
Roundtrip
found 19 hours ago
Select United flight, departing Wed, Jun 11 from General Francisco Mujica Intl. to Des Moines Intl., returning Wed, Jun 25, priced at $612 found 19 hours ago

Cheap Flights to De Soto

Fall in love at first flight with your vacation to De Soto by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to De Soto on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in De Soto, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to De Soto

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to De Soto with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to De Soto?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to De Soto are in April, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to De Soto?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to De Soto.

What airport is best to fly into De Soto?

When you’re planning your trip to De Soto, convenience is the name of the game. Luckily, De Soto Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your De Soto must-do list.

How much are flights to De Soto?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to De Soto on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $191, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to De Soto?

The trick to saving a stack of cash on your flight to De Soto? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $191 right now, why wait?

De Soto Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$190

Last Minute Hotel Deals in De Soto

Edgetowner Motel
Edgetowner Motel
2.5 out of 5
804 Guthrie St, De Soto, IA
The price is $50 per night from Apr 17 to Apr 18
$50
includes taxes & fees
Apr 17 - Apr 18
Book a stay at this business-friendly motel in De Soto. Enjoy free parking, a business center, and a garden. Popular attractions Van Meter Recreation Complex ...
6/10 (133 reviews)
"Lol"

Reviewed on Mar 30, 2025

Edgetowner Motel
Stoney Creek Hotel Des Moines - Johnston
Stoney Creek Hotel Des Moines - Johnston
2.5 out of 5
5291 Stoney Creek Court, Johnston, IA
The price is $122 per night from Apr 17 to Apr 18
$122
includes taxes & fees
Apr 17 - Apr 18
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (1,656 reviews)
Great place good location
"It was good, rooms are spacious, pool area is nice"

Reviewed on Apr 12, 2025

Stoney Creek Hotel Des Moines - Johnston
Fairfield Inn and Suites by Marriott Des Moines West
Fairfield Inn and Suites by Marriott Des Moines West
2.5 out of 5
7225 Vista Dr, West Des Moines, IA
The price is $88 per night from May 4 to May 5
$88
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,006 reviews)
"Stopped here on our way to Nebraska."

Reviewed on Apr 11, 2025

Fairfield Inn and Suites by Marriott Des Moines West
Days Inn & Suites by Wyndham Des Moines Airport
Days Inn & Suites by Wyndham Des Moines Airport
2 out of 5
1901 Hackley Ave, Des Moines, IA
The price is $78 per night from Apr 20 to Apr 21
$78
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,463 reviews)
"The staff was pleasant and helpful. They had a great breakfast. The room was very clean."

Reviewed on Apr 12, 2025

Days Inn & Suites by Wyndham Des Moines Airport
Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Ramada Tropics Resort & Conf Center by Wyndham Des Moines
3 out of 5
5000 Merle Hay Rd, Urbandale, IA
The price is $87 per night from May 4 to May 5
$87
includes taxes & fees
May 4 - May 5
Book a stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.6/10 (396 reviews)
"It was ok . Could have been better staffed"

Reviewed on Apr 11, 2025

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Wildwood Lodge
Wildwood Lodge
3 out of 5
11431 Forest Ave, Clive, IA
The price is $122 per night from Apr 17 to Apr 18
$122
includes taxes & fees
Apr 17 - Apr 18
Stay at this 3-star hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,232 reviews)
"Our favorite place to stay in Des Moines!"

Reviewed on Apr 13, 2025

Wildwood Lodge
SpringHill Suites Des Moines West
SpringHill Suites Des Moines West
3 out of 5
1236 Jordan Creek Pkwy, West Des Moines, IA
The price is $93 per night from May 4 to May 5
$93
includes taxes & fees
May 4 - May 5
Stay at this 3-star business-friendly hotel in West Des Moines. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast ...
8.4/10 Very Good! (1,002 reviews)
"Very nice and clean"

Reviewed on Apr 12, 2025

SpringHill Suites Des Moines West
Sonesta Essential Des Moines
Sonesta Essential Des Moines
2 out of 5
4755 Merle Hay Road, Des Moines, IA
The price is $74 per night from Apr 27 to Apr 28
$74
includes taxes & fees
Apr 27 - Apr 28
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.2/10 Good! (1,000 reviews)
"People above us were load they took care of it right away. Overall the stay was fine remodeled rooms. Pillows were Terrible"

Reviewed on Apr 13, 2025

Sonesta Essential Des Moines
See all 366 properties in De Soto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.