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Flights to Antofagasta Region starting at

Have you been telling yourself, “2025 is the year I travel more and sit less”? Well, here we are and there you are. So, where are you going? Looks like a flight to Antofagasta Region is calling. Good thing we can help you bag that flight out of town for cheap, so you can get your resolutions resolved.

Travel like you mean it

When you land it’s not straight to the tourist traps for you. You have things to do and see in Antofagasta Region that aren’t on a map or in the “Best of. . .” guides. You know this region is filled with hidden haunts, locals-only know favorites, and the off-beat-so-weird-it’s-amazing places. And you plan to find every last one of them. Good thing you’ll save a grip of cash on your flight so you can daytrip far and wide.

You won’t have to wing it

So how do you score that killer deal on a flight to Antofagasta Region? Easy, go through us. These aren’t pie in the sky deals, but ones you can actually score. Filter flights to Antofagasta Region by:

  • Hotwire Hot Rate: Do you have a flexible schedule? Hit up the Hotwire Hot Rate and land a super cheap flight to Antofagasta Region. We’ll reveal the airline and exact time after you book.
  • Price: How low can we go? Find out. We have prices from to .
  • Duration: Want to get to Antofagasta Region as fast as you can? Or maybe you don’t mind taking your time to save a few bucks here and there.
  • Departure or Arrival: Like to arrive in the a.m. to get your day going? Or are you a night owl that knows the best fun happens late night? The choice is yours.

So are you going to live up to those travel plans or kick the can to next year? Book your flight to Antofagasta Region today and get going.

Last Minute Hotel Deals in Antofagasta Region

Park Hotel Calama

Park Hotel Calama

3.5 out of 5
Alcalde Jose Lira 1392, Calama, Antofagasta
Stay at this 3.5-star business-friendly hotel in Calama. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Calama Municipal Stadium and ...
8/10 Very Good! (282 reviews)
Room was clean and the bathroom was efficient. Good selection of restaurant food to late into the evening and a very good breakfast. Lots to eat. Also very close to the airport so perfect for a one night stop

Reviewed on Nov 10, 2025

Opens in a new windowPark Hotel Calama
Diego de Almagro San Pedro de Atacama

Diego de Almagro San Pedro de Atacama

3 out of 5
Toconao 460, San Pedro de Atacama, Antofagasta
Stay at this 3-star hotel in San Pedro de Atacama. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (309 reviews)
Ótimo, EXCELENTE, maravilhoso Sem duvidas eu recomendo muito.

Reviewed on Nov 1, 2025

Opens in a new windowDiego de Almagro San Pedro de Atacama
Noi Casa Atacama

Noi Casa Atacama

4.5 out of 5
Tocopilla E-8, San Pedro de Atacama, Antofagasta
Stay at this 4.5-star luxury hotel in San Pedro de Atacama. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our ...
8.6/10 Excellent! (239 reviews)
Great room. Comfortable and great service. Well located close to the center of town. Pleasant and helpful staff. Arranged for us some amazing excursions. We had a great stay. Thank you!

Reviewed on Nov 9, 2025

Opens in a new windowNoi Casa Atacama
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Hotel Cumbres San Pedro de Atacama

Hotel Cumbres San Pedro de Atacama

4 out of 5
Avenida Las Chilcas S/N, Lote 10 Parcela 2, San Pedro de Atacama, Antofagasta
Stay at this 4-star luxury hotel in San Pedro de Atacama. Enjoy free WiFi, free parking, and 3 outdoor pools. Popular attractions Plaza de San Pedro de Atacama ...
8.8/10 Excellent! (469 reviews)
so nice 😍

Reviewed on Oct 24, 2025

Opens in a new windowHotel Cumbres San Pedro de Atacama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.