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Hotels in Isla Santay

Choose from 402 Isla Santay Hotel Deals

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 out of 5
Calle Numa Pompilio Llona S N, Ciudad del Rio - Puerto Santa Ana, Guayaquil, Guayas
  • 7 min drive from U.S. Consulate General
Stay at this 4.5-star luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (1,003 reviews)
"Excelente hotel, valió cada centavo"

Reviewed on Sep 30, 2025

Wyndham Guayaquil Puerto Santa Ana
Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

3.5 out of 5
Av. de Las Américas,junto al Aeropuerto, Intl. Jose Joaquin de Olmedo, Guayaquil, Guayas
  • 10 min drive from U.S. Consulate General
Stay at this 3.5-star business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
9.2/10 Wonderful! (1,011 reviews)
"Great staff and restaurant"

Reviewed on Oct 11, 2025

Holiday Inn Guayaquil Airport by IHG
Oro Verde Guayaquil

Oro Verde Guayaquil

5 out of 5
9 De Octubre Y Garcia Moreno, Guayaquil, Guayas
  • 5 min drive from U.S. Consulate General
Book a stay at this spa hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in our ...
9.4/10 Exceptional! (1,010 reviews)
"Ok"

Reviewed on Oct 10, 2025

Oro Verde Guayaquil
Hilton Colon Guayaquil

Hilton Colon Guayaquil

4.5 out of 5
Av Francisco de Orellana Mz 111, Guayaquil
  • 7 min drive from U.S. Consulate General
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (778 reviews)
"Excellent Stay at Hilton Guayaquil I had a wonderful experience at the Hilton Hotel Guayaquil. The staff was welcoming and attentive, the room was spacious, clean, and very comfortable, and the amenities were top-notch. The location is convenient for both business and leisure, and the breakfast buffet ..."

Reviewed on Oct 10, 2025

Hilton Colon Guayaquil
Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil

3.5 out of 5
Av. Francisco De Orellana #236, Guayaquil, Guayas
  • 6 min drive from U.S. Consulate General
Stay at this 3.5-star spa hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,004 reviews)
"Muy limpio, excelente ubicación y todo el personal es muy cordial"

Reviewed on Aug 20, 2025

Courtyard by Marriott Guayaquil
Wyndham Garden Guayaquil

Wyndham Garden Guayaquil

3.5 out of 5
Juan Tanca Marengo Ave, Abel Romero St. Plaza Del Sol, Guayaquil, Guayas
  • 7 min drive from U.S. Consulate General
Stay at this 3.5-star business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,008 reviews)
"The hotel was clean and the staff was extremely friendly — even though the shuttle doesn’t run from midnight to the early hours, they arranged a taxi for me to get to the airport. Overall, five stars!"

Reviewed on Oct 8, 2025

Wyndham Garden Guayaquil
Grand Hotel Guayaquil, an Ascend Collection Hotel

Grand Hotel Guayaquil, an Ascend Collection Hotel

4 out of 5
Boyaca 1615, Guayaquil, Guayas
  • 6 min drive from U.S. Consulate General
Stay at this 4-star family-friendly hotel in Guayaquil. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (964 reviews)
"I love it"

Reviewed on Oct 9, 2025

Grand Hotel Guayaquil, an Ascend Collection Hotel
Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels

4 out of 5
Clemente Ballén 406, entre Chile y Chimborazo, Guayaquil, Guayas
  • 6 min drive from U.S. Consulate General
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the comfy ...
9/10 Wonderful! (1,002 reviews)
"Excellent"

Reviewed on Oct 8, 2025

Unipark by Oro Verde Hotels
Ibis Styles El Malecon Guayaquil

Ibis Styles El Malecon Guayaquil

4 out of 5
Av Malecon Simon Bolivar, Guayaquil
  • 6 min drive from U.S. Consulate General
Stay at this 4-star business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (254 reviews)
"Great location and great hotel"

Reviewed on Sep 29, 2025

Ibis Styles El Malecon Guayaquil
Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel

5 out of 5
Av. Constitucion, Plaza del Sol, Frente al Mall del Sol, Guayaquil, Guayas
  • 8 min drive from U.S. Consulate General
Stay at this 5-star luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (587 reviews)
"The Front Desk Andrea was amazing and very kind."

Reviewed on Oct 5, 2025

Sheraton Guayaquil Hotel
TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport

4.5 out of 5
Av. Joaquín Orrantia y L. Benitez, Guayaquil, Guayas
  • 8 min drive from U.S. Consulate General
Stay at this 4.5-star luxury hotel in Guayaquil. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the breakfast and the helpful staff in ...
8.8/10 Excellent! (1,008 reviews)
"It’s excellent very good"

Reviewed on Oct 10, 2025

TRYP by Wyndham Guayaquil Airport
Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport

4 out of 5
Av 33. Ciudadela La Garzota, Mz. 83 Solar 6-9, Guayaquil, Guayas
  • 9 min drive from U.S. Consulate General
Stay at this 4-star family-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.6/10 Excellent! (212 reviews)
"Check in was smooth. I chose this hotel due to close proximity to the airport, however staff shared that although the hotel is a 9 minute walk, it's best to take a $5 taxi. I paid way more than I intended. Especially hotel tax added on and I was forced to pay for breakfast while making reservation ..."

Reviewed on Sep 29, 2025

Hotel Puerto Pacifico Guayaquil Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Isla Santay

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Isla Santay.

Choosing the right hotel in Guayas has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Isla Santay’s 402 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $68. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Isla Santay hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Isla Santay. No matter your reason for visiting Isla Santay, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Isla Santay hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Isla Santay for as low as $68.

How many hotels are there in Isla Santay?

With over 402 hotels in Isla Santay, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $68.

How to find cheap car rentals in Isla Santay?

Finding a cheap car rental deal in Isla Santay is as easy as scoring cheap hotels in Isla Santay. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.