Search Deals onMain Street Cultural District Vacation Packages
Main Street Cultural District Flight + Hotel Packages
Price found within the past 48 hours. Click for updated prices.

Motel 6 West Des Moines, IA
Price was $452, price is now $417 per person
$417
per person
Oct 31 - Nov 5
found 5 hours ago
Roundtrip non-stop flight included
Tampa (TPA) to Des Moines (DSM)
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Jordan Creek Town Center and Des Moines Golf & Country Club are located nearby.

AmericInn by Wyndham Des Moines Airport
Price was $573, price is now $489 per person
$489
per person
Oct 31 - Nov 5
found 5 hours ago
Roundtrip non-stop flight included
Tampa (TPA) to Des Moines (DSM)
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Casey's Center and Air Lanes Bowling Center are located nearby.

Microtel Inn & Suites by Wyndham Urbandale/Des Moines
Price was $577, price is now $510 per person
$510
per person
Oct 31 - Nov 5
found 5 hours ago
Roundtrip non-stop flight included
Tampa (TPA) to Des Moines (DSM)
Book a stay at this business-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. Popular attractions Merle Hay Mall and Pump It Up are located nearby.

Hampton Inn & Suites Des Moines Downtown
Price was $671, price is now $597 per person
$597
per person
Oct 31 - Nov 5
found 5 hours ago
Roundtrip non-stop flight included
Tampa (TPA) to Des Moines (DSM)
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Casey's Center and Iowa State Fairgrounds are located nearby.

Baymont by Wyndham Des Moines Airport
Price was $610, price is now $544 per person
$544
per person
Oct 31 - Nov 5
found 5 hours ago
Roundtrip non-stop flight included
Tampa (TPA) to Des Moines (DSM)
Book a stay at this family-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Jordan Creek Town Center and Casey's Center are located nearby.

Residence Inn Des Moines Downtown
Price was $651, price is now $583 per person
$583
per person
Oct 31 - Nov 5
found 5 hours ago
Roundtrip non-stop flight included
Tampa (TPA) to Des Moines (DSM)
Stay at this 3-star hotel in Des Moines. Enjoy free breakfast, a fitness center, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Casey's Center and Iowa State Fairgrounds are located nearby.

AmericInn by Wyndham Johnston Des Moines
Price was $543, price is now $490 per person
$490
per person
Oct 31 - Nov 5
found 5 hours ago
Roundtrip non-stop flight included
Tampa (TPA) to Des Moines (DSM)
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Casey's Center and Merle Hay Mall are located nearby.

Hampton Inn Des Moines-Airport
Price was $598, price is now $549 per person
$549
per person
Oct 31 - Nov 5
found 5 hours ago
Roundtrip non-stop flight included
Tampa (TPA) to Des Moines (DSM)
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Casey's Center and Air Lanes Bowling Center are located nearby.

Hilton Des Moines Downtown
Price was $818, price is now $751 per person
$751
per person
Oct 31 - Nov 5
found 5 hours ago
Roundtrip non-stop flight included
Tampa (TPA) to Des Moines (DSM)
Stay at this 3.5-star business-friendly hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Casey's Center and Iowa State Fairgrounds are located nearby.

Wildwood Lodge
Price was $688, price is now $633 per person
$633
per person
Oct 31 - Nov 5
found 5 hours ago
Roundtrip non-stop flight included
Tampa (TPA) to Des Moines (DSM)
Stay at this 3-star hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Jordan Creek Town Center and Clive Aquatic Center are located nearby.

Home2 Suites by Hilton Des Moines at Drake University
Price was $608, price is now $560 per person
$560
per person
Oct 31 - Nov 5
found 5 hours ago
Roundtrip non-stop flight included
Tampa (TPA) to Des Moines (DSM)
Stay at this 3-star business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Casey's Center and Iowa State Fairgrounds are located nearby.

Days Inn & Suites by Wyndham Des Moines Airport
Price was $545, price is now $502 per person
$502
per person
Oct 31 - Nov 5
found 5 hours ago
Roundtrip non-stop flight included
Tampa (TPA) to Des Moines (DSM)
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Casey's Center and Air Lanes Bowling Center are located nearby.
3-4 Night Vacations in Main Street Cultural District
Price found within the past 48 hours. Click for updated prices.



5-7 Night Vacations in Main Street Cultural District
Price found within the past 48 hours. Click for updated prices.



Main Street Cultural District Last Minute Hotel Deals

Gateway Hotel and Conference Center at Iowa State University
2100 Green Hills Drive, Ames, IA
Stay at this 3-star business-friendly hotel in Ames. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms ...

Comfort Inn and Suites Ames near ISU Campus
603 South 16th Street, Ames, IA
Book a stay at this golf hotel in Ames. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff and the clean rooms in ...

Country Inn & Suites by Radisson, Ames, IA
2605 Se 16th St, Ames, IA
Book a stay at this business-friendly hotel in Ames. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

GrandStay Hotel & Suites
1606 S Kellogg Ave, Ames, IA
Book a stay at this business-friendly hotel in Ames. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...

AmericInn by Wyndham Ames
2507 SE 16th St., Ames, IA
Book a stay at this business-friendly hotel in Ames. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. ...

SpringHill Suites by Marriott Ames
1810 SE 16TH STREET, Ames, IA
Book a stay at this business-friendly hotel in Ames. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...

Sonesta Essential Ames
1400 S Dayton Place, Ames, IA
Book a stay at this family-friendly hotel in Ames. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...

Microtel Inn & Suites by Wyndham Ames
2216 Se 16th St, Ames, IA
Book a stay at this business-friendly hotel in Ames. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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