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Featured Opelousas Resorts & Hotels with Spas
Holiday Inn Express & Suites Opelousas, an IHG Hotel
5696 I-49 N Service Rd, Opelousas, LA
Fully refundable
Stay at this 3-star business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in Opelousas
- Hotels with a Pool in Opelousas
- Historic Hotels in Opelousas
- Hotels with Free Parking in Opelousas
- Family Hotels in Opelousas
- Pet-friendly Hotels in Opelousas
- Casinos in Opelousas
- Hotel Wedding Venues in Opelousas
- Hotels with smoking rooms in Opelousas
- Hotels with an Indoor Pool in Opelousas
- Hotels with Hot Tubs in Opelousas
Top Points of Interests in Opelousas
- Hotels near Evangeline Downs Racetrack & Casino
- Hotels near St. Landry Catholic Church
- Hotels near Louisiana Orphan Train Museum
- Hotels near Cajundome
- Hotels near University of Louisiana at Lafayette
- Hotels near Acadian Village
- Hotels near CIty Club at River Ranch
- Hotels near Cajun Field
- Hotels near Moore Park
- Hotels near Acadiana Mall
- Hotels near Frem Boustany Convention Center at The Heymann Center
Cities near Opelousas
- Lafayette Hotels (21.68 mi)
- Gulf Coast Hotels (114.46 mi)
- Scott Hotels (20.58 mi)
- Breaux Bridge Hotels (20.98 mi)
- Broussard Hotels (27.63 mi)
- Eunice Hotels (20.18 mi)
- Crowley Hotels (28.13 mi)
- Youngsville Hotels (30.41 mi)
- Oakdale Hotels (39.46 mi)
- Rayne Hotels (23.43 mi)
- The South Hotels (233.48 mi)
- Carencro Hotels (15.07 mi)
- Ville Platte Hotels (15.53 mi)
- St. Martinville Hotels (32.07 mi)
- Duson Hotels (23.45 mi)
- Bunkie Hotels (30.06 mi)
- Central United States Hotels (587.96 mi)
- Southern Louisiana Hotels (34.4 mi)
- Mamou Hotels (21.24 mi)
- Henderson Hotels (23.06 mi)
Car Rentals Near Opelousas
- Car rentals in Lafayette
- Car rentals in Gulf Coast
- Car rentals in Scott
- Car rentals in Breaux Bridge
- Car rentals in Broussard
- Car rentals in Eunice
- Car rentals in Crowley
- Car rentals in Youngsville
- Car rentals in Oakdale
- Car rentals in Rayne
- Car rentals in The South
- Car rentals in Carencro
- Car rentals in Ville Platte
- Car rentals in St. Martinville
- Car rentals in Duson
- Car rentals in Bunkie
Top Spa Resort Destinations
- Annapolis Spa Hotels
- Ottawa Valley Spa Hotels
- Tallahassee Spa Hotels
- Appalachian Mountains Spa Hotels
- Corpus Christi Spa Hotels
- Raleigh Spa Hotels
- Syracuse Spa Hotels
- Chattanooga Spa Hotels
- Grand Canyon Spa Hotels
- Toledo Spa Hotels
- Edmonton Spa Hotels
- El Paso Spa Hotels
- Omaha Spa Hotels
- Cincinnati Spa Hotels
- Fargo Spa Hotels
- Des Moines Spa Hotels
- Dayton Spa Hotels
- Flagstaff Spa Hotels
- Little Rock Spa Hotels
- Waco Spa Hotels
Top Booked Hotels in Opelousas
- Evangeline Downs Hotel, Ascend Hotel Collection
- Motel 6 Opelousas, LA
- Days Inn & Suites by Wyndham Opelousas
- Holiday Inn Express & Suites Opelousas, an IHG Hotel
- Hampton Inn Opelousas
- Quality Inn Opelousas
- Studio 6 Opelousas, LA
- La Quinta Inn & Suites by Wyndham Lafayette Oil Center
- DoubleTree by Hilton Hotel Lafayette
- Homewood Suites by Hilton Lafayette, LA
- Hilton Garden Inn Lafayette/Cajundome
- Microtel Inn & Suites by Wyndham Scott/Lafayette