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Featured Opelousas Family Hotels
Evangeline Downs Hotel, Ascend Hotel Collection
2235 Creswell Ln Ext, Lot B, Opelousas, LA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Holiday Inn Express & Suites Opelousas by IHG
5696 I-49 N Service Rd, Opelousas, LA
Fully refundable
Stay at this 3-star business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Spark by Hilton Opelousas
5454 I-49 North Service Rd., Opelousas, LA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
Days Inn & Suites by Wyndham Opelousas
5761 I-49 S Service Rd, Opelousas, LA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Studio 6 Opelousas, LA
5791 I-49 S Service Road, Opelousas, LA
Fully refundableReserve now, pay when you stay
Stay at this hotel in Opelousas. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Evangeline Downs Racetrack & Casino and South Park ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels with Pools in Opelousas
Evangeline Downs Hotel, Ascend Hotel Collection
2235 Creswell Ln Ext, Lot B, Opelousas, LA
Stay at this 3-star business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (680 reviews)
"Nice and clean with friendly staff"
Reviewed on Jun 16, 2025
Holiday Inn Express & Suites Opelousas by IHG
5696 I-49 N Service Rd, Opelousas, LA
Stay at this 3-star business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (172 reviews)
"Very clean and comfortable!"
Reviewed on Jun 16, 2025
Spark by Hilton Opelousas
5454 I-49 North Service Rd., Opelousas, LA
Book a stay at this business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
7.4/10 Good! (345 reviews)
"Very clean, staff very friendly and trustworthy love it there"
Reviewed on Jun 9, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels With Connecting Rooms in Opelousas
Days Inn & Suites by Wyndham Opelousas
5761 I-49 S Service Rd, Opelousas, LA
Book a stay at this business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Evangeline Downs Hotel, Ascend Hotel Collection
2235 Creswell Ln Ext, Lot B, Opelousas, LA
Stay at this 3-star business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options
- Hotels with a Pool in Opelousas
- Historic Hotels in Opelousas
- Hotels with Free Parking in Opelousas
- Pet-friendly Hotels in Opelousas
- Casinos in Opelousas
- Hotel Wedding Venues in Opelousas
- Hotels with smoking rooms in Opelousas
- Hotels with an Indoor Pool in Opelousas
- Hotels with Hot Tubs in Opelousas
- Resorts & Hotels with Spas in Opelousas
Top Points of Interests in Opelousas
- Hotels near Evangeline Downs Racetrack & Casino
- Hotels near Louisiana Orphan Train Museum
- Hotels near St. Landry Catholic Church
- Hotels near University of Louisiana at Lafayette
- Hotels near Cajundome
- Hotels near Acadian Village
- Hotels near CIty Club at River Ranch
- Hotels near Girard Park
- Hotels near Chicot State Park
- Hotels near Vermilionville Historic Village
- Hotels near Cajun Field
Cities near Opelousas
- Lafayette Hotels (21.68 mi)
- Gulf Coast Hotels (146.43 mi)
- Scott Hotels (20.58 mi)
- Breaux Bridge Hotels (20.98 mi)
- Broussard Hotels (27.63 mi)
- Youngsville Hotels (30.41 mi)
- Crowley Hotels (28.13 mi)
- Eunice Hotels (20.18 mi)
- Rayne Hotels (23.43 mi)
- Oakdale Hotels (39.46 mi)
- Carencro Hotels (15.07 mi)
- Bunkie Hotels (30.06 mi)
- St. Martinville Hotels (32.07 mi)
- Ville Platte Hotels (15.53 mi)
- Duson Hotels (23.45 mi)
- Southern Louisiana Hotels (34.4 mi)
- Henderson Hotels (23.06 mi)
- Church Point Hotels (12.02 mi)
- Mamou Hotels (21.24 mi)
- Sunset Hotels (8.47 mi)
Car Rentals Near Opelousas
- Car rentals in Lafayette
- Car rentals in Gulf Coast
- Car rentals in Scott
- Car rentals in Breaux Bridge
- Car rentals in Broussard
- Car rentals in Youngsville
- Car rentals in Crowley
- Car rentals in Eunice
- Car rentals in Rayne
- Car rentals in Oakdale
- Car rentals in Carencro
- Car rentals in Bunkie
- Car rentals in St. Martinville
- Car rentals in Ville Platte
- Car rentals in Duson
- Car rentals in Southern Louisiana
Top Family Hotel Destinations
- Las Vegas Family Hotels
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- Ocean City Family Hotels
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- Reno Family Hotels
- Colorado Springs Family Hotels
- Phoenix Family Hotels
- Niagara Falls Family Hotels
- New York Family Hotels
- Whistler Family Hotels
- Houston Family Hotels
- Fort Walton Beach Family Hotels
- Pensacola Beach Family Hotels
- Tampa Family Hotels
- Myrtle Beach Family Hotels
- Miami Beach Family Hotels
- Birmingham Family Hotels
Top Booked Hotels in Opelousas
- Evangeline Downs Hotel, Ascend Hotel Collection
- Holiday Inn Express & Suites Opelousas by IHG
- Motel 6 Opelousas, LA
- Days Inn & Suites by Wyndham Opelousas
- Spark by Hilton Opelousas
- Hampton Inn Opelousas
- Studio 6 Opelousas, LA
- Microtel Inn & Suites by Wyndham Scott/Lafayette
- DoubleTree by Hilton Hotel Lafayette
- La Quinta Inn & Suites by Wyndham Lafayette Oil Center
- Comfort Suites Oil Center
- Hilton Garden Inn Lafayette/Cajundome
- Tru by Hilton Lafayette River Ranch
- Howard Johnson by Wyndham Scott Lafayette
- Holiday Inn Express Hotel & Suites Lafayette South by IHG