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Featured Opelousas Family Hotels
Evangeline Downs Hotel, Ascend Hotel Collection
2235 Creswell Ln Ext, Lot B, Opelousas, LA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Holiday Inn Express & Suites Opelousas by IHG
5696 I-49 N Service Rd, Opelousas, LA
Fully refundable
Stay at this 3-star business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Spark by Hilton Opelousas
5454 I-49 North Service Rd., Opelousas, LA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
Days Inn & Suites by Wyndham Opelousas
5761 I-49 S Service Rd, Opelousas, LA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Studio 6 Opelousas, LA
5791 I-49 S Service Road, Opelousas, LA
Fully refundableReserve now, pay when you stay
Stay at this hotel in Opelousas. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Evangeline Downs Racetrack & Casino and South Park ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels with Pools in Opelousas
Evangeline Downs Hotel, Ascend Hotel Collection
2235 Creswell Ln Ext, Lot B, Opelousas, LA
Stay at this 3-star business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (643 reviews)
"very nice room!"
Reviewed on Mar 31, 2025
Holiday Inn Express & Suites Opelousas by IHG
5696 I-49 N Service Rd, Opelousas, LA
Stay at this 3-star business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (142 reviews)
"I liked that it was convenient. Easy access to the highway and local shopping. Was very close to a friend I was visiting. Ice make did stop working during my stay. Breakfast was a little cold when I tried it around 8 am."
Reviewed on Apr 2, 2025
Spark by Hilton Opelousas
5454 I-49 North Service Rd., Opelousas, LA
Book a stay at this business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
7.2/10 Good! (332 reviews)
Softball trip
"Big clean room. Nice location . Only complaint was sound proofing, could hear outside noises and voices in hall way."
Reviewed on Mar 26, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels With Connecting Rooms in Opelousas
Days Inn & Suites by Wyndham Opelousas
5761 I-49 S Service Rd, Opelousas, LA
Book a stay at this business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Evangeline Downs Hotel, Ascend Hotel Collection
2235 Creswell Ln Ext, Lot B, Opelousas, LA
Stay at this 3-star business-friendly hotel in Opelousas. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options
- Hotels with a Pool in Opelousas
- Historic Hotels in Opelousas
- Hotels with Free Parking in Opelousas
- Pet-friendly Hotels in Opelousas
- Casinos in Opelousas
- Hotel Wedding Venues in Opelousas
- Hotels with smoking rooms in Opelousas
- Hotels with an Indoor Pool in Opelousas
- Hotels with Hot Tubs in Opelousas
- Resorts & Hotels with Spas in Opelousas
Top Points of Interests in Opelousas
- Hotels near Evangeline Downs Racetrack & Casino
- Hotels near St. Landry Catholic Church
- Hotels near Louisiana Orphan Train Museum
- Hotels near Cajundome
- Hotels near University of Louisiana at Lafayette
- Hotels near Acadian Village
- Hotels near CIty Club at River Ranch
- Hotels near Moore Park
- Hotels near Cajun Field
- Hotels near Vermilionville
- Hotels near Vermilionville Historic Village
Cities near Opelousas
- Lafayette Hotels (21.68 mi)
- Gulf Coast Hotels (114.46 mi)
- Breaux Bridge Hotels (20.98 mi)
- Scott Hotels (20.58 mi)
- Broussard Hotels (27.63 mi)
- Youngsville Hotels (30.41 mi)
- Eunice Hotels (20.18 mi)
- Crowley Hotels (28.13 mi)
- Rayne Hotels (23.43 mi)
- Oakdale Hotels (39.46 mi)
- St. Martinville Hotels (32.07 mi)
- Carencro Hotels (15.07 mi)
- Ville Platte Hotels (15.53 mi)
- Duson Hotels (23.45 mi)
- Mamou Hotels (21.24 mi)
- Bunkie Hotels (30.06 mi)
- Henderson Hotels (23.06 mi)
- Southern Louisiana Hotels (34.4 mi)
- Sunset Hotels (8.47 mi)
- Church Point Hotels (12.02 mi)
Car Rentals Near Opelousas
- Car rentals in Lafayette
- Car rentals in Gulf Coast
- Car rentals in Breaux Bridge
- Car rentals in Scott
- Car rentals in Broussard
- Car rentals in Youngsville
- Car rentals in Eunice
- Car rentals in Crowley
- Car rentals in Rayne
- Car rentals in Oakdale
- Car rentals in St. Martinville
- Car rentals in Carencro
- Car rentals in Ville Platte
- Car rentals in Duson
- Car rentals in Mamou
- Car rentals in Bunkie
Top Family Hotel Destinations
- Las Vegas Family Hotels
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- Houston Family Hotels
- Fort Walton Beach Family Hotels
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- Tampa Family Hotels
- Myrtle Beach Family Hotels
- Miami Beach Family Hotels
- Birmingham Family Hotels
Top Booked Hotels in Opelousas
- Evangeline Downs Hotel, Ascend Hotel Collection
- Days Inn & Suites by Wyndham Opelousas
- Holiday Inn Express & Suites Opelousas by IHG
- Motel 6 Opelousas, LA
- Spark by Hilton Opelousas
- Hampton Inn Opelousas
- Studio 6 Opelousas, LA
- DoubleTree by Hilton Hotel Lafayette
- La Quinta Inn & Suites by Wyndham Lafayette Oil Center
- Microtel Inn & Suites by Wyndham Scott/Lafayette
- Holiday Inn Hotel & Suites Lafayette North by IHG
- Staybridge Suites Lafayette by IHG
- Candlewood Suites Lafayette - River Ranch by IHG
- Holiday Inn Express Hotel & Suites Lafayette by IHG
- Tru by Hilton Lafayette River Ranch