Search for Cheap Deals on
Hotels in Picayune

Check Last Minute Picayune Hotel Deals

Tonight Jun 19 - Jun 20This weekend Jun 19 - Jun 21

Choose from 1069 Picayune Hotel Deals

Holiday Inn Express Picayune-Stennis Space Center by IHG

Holiday Inn Express Picayune-Stennis Space Center by IHG

2.5 out of 5
1001 Dauphin Street Picayune MS
  • 21 min walk from Crosby Arboretum
Book a stay at this business-friendly hotel in Picayune. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (685 reviews)
"Close to family"

Reviewed on May 13, 2026

Holiday Inn Express Picayune-Stennis Space Center by IHG
Heritage Inn Picayune

Heritage Inn Picayune

2 out of 5
1122 Memorial Blvd. Picayune MS
  • 20 min walk from Crosby Arboretum
Stay at this hotel in Picayune. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (303 reviews)
"Amazing experience...cleanliness I loved it 😍 Bed quality and softness will take your whole day tiredness out ... I LOVED THE MATRESS"

Reviewed on May 27, 2026

Heritage Inn Picayune
Ramada by Wyndham Diamondhead I-10/Gulfport

Ramada by Wyndham Diamondhead I-10/Gulfport

2.5 out of 5
103 Live Oak Drive Diamondhead MS
  • 34 min drive from Crosby Arboretum
Book a stay at this golf hotel in Diamondhead. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
7.8/10 Good! (712 reviews)
"We stayed two non-consecutive nights. One on our way to our destination and the next on our return trip. On 5/28/26 we stopped on our drive to Florida. We were surprised with the room, it was very clean, quiet, and the A/C worked fine to remove the humidity which during this time was more important ..."

Reviewed on Jun 8, 2026

Ramada by Wyndham Diamondhead I-10/Gulfport
Hollywood Casino Gulf Coast

Hollywood Casino Gulf Coast

3.5 out of 5
711 Hollywood Blvd Bay St Louis MS
  • 40 min drive from Crosby Arboretum
Book a stay at this spa resort in Bay St Louis. Enjoy free parking, a full-service spa, and 3 restaurants. Our guests praise the pool and the helpful staff in ...
8/10 Very Good! (1,000 reviews)
"We only liked the pool The hotel had hair in the bed and hair from a person shaving in soap dish"

Reviewed on Jun 14, 2026

Hollywood Casino Gulf Coast
Quality Inn Slidell I-10

Quality Inn Slidell I-10

2.5 out of 5
794 E I 10 Service Rd Slidell LA
  • 38 min drive from Crosby Arboretum
Book a stay at this business-friendly hotel in Slidell. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Skater's Paradise and Rue Rochelle ...
7.8/10 Good! (468 reviews)
"Waas dirty. We stayed for a week and house keeping didn't come unless we requested it. Horrible won't stay there again"

Reviewed on Jun 13, 2026

Quality Inn Slidell I-10
Pass Bungalows

Pass Bungalows

4.5 out of 5
100 W Scenic Dr Pass Christian MS
  • 48 min drive from Crosby Arboretum
Book a stay at this luxury aparthotel in Pass Christian. Enjoy free WiFi, free parking, and onsite spa services. Popular attractions Thou Art Gallery & GIfts ...
10/10 Exceptional! (14 reviews)
"The bungalows were amazing."

Reviewed on Jun 17, 2026

Pass Bungalows
Silver Slipper Casino & Hotel - Adults Only

Silver Slipper Casino & Hotel - Adults Only

3.5 out of 5
5000 South Beach Boulevard Bay St Louis MS
  • 48 min drive from Crosby Arboretum
Book a stay at this beach hotel in Bay St Louis. Enjoy free WiFi, free parking, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in ...
8.6/10 Excellent! (1,001 reviews)
"The beds were horrible !!!"

Reviewed on Jun 16, 2026

Silver Slipper Casino & Hotel - Adults Only
SpringHill Suites by Marriott Slidell

SpringHill Suites by Marriott Slidell

2.5 out of 5
2214 Ruth Garrett Way Slidell LA
  • 42 min drive from Crosby Arboretum
Book a stay at this business-friendly hotel in Slidell. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (417 reviews)
"Great stay. We love it. Thanks"

Reviewed on Jun 14, 2026

SpringHill Suites by Marriott Slidell
The Southern Hotel

The Southern Hotel

3.5 out of 5
428 E. Boston St Covington LA
  • 44 min drive from Crosby Arboretum
Book a stay at this business-friendly hotel in Covington. Enjoy free parking, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
9.6/10 Exceptional! (620 reviews)
"The Southern Hotel is our new favorite place. Everything was above par.One of the desk clerks was interested in history. My great grandfather opened The Southern Hotel as a hospital in the early 1900s. Later building "The Fenwick Sanatarium" she had read about it. Her interest made me feel special. ..."

Reviewed on Jun 10, 2026

The Southern Hotel
Candlewood Suites Slidell Northshore by IHG

Candlewood Suites Slidell Northshore by IHG

2.5 out of 5
100 Holiday Blvd Slidell LA
  • 35 min drive from Crosby Arboretum
Book a stay at this business-friendly hotel in Slidell. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff in our ...
8.4/10 Very Good! (746 reviews)
"Great stay! Staff was so helpful, room was very clean!"

Reviewed on Jun 18, 2026

Candlewood Suites Slidell Northshore by IHG
Country Inn & Suites by Radisson, Covington, LA

Country Inn & Suites by Radisson, Covington, LA

3 out of 5
130 Holiday Blvd Covington LA
  • 42 min drive from Crosby Arboretum
Book a stay at this business-friendly hotel in Covington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,002 reviews)
"Great place to stay and staff is very friendly!"

Reviewed on Jun 18, 2026

Country Inn & Suites by Radisson, Covington, LA
Best Western Slidell Hotel

Best Western Slidell Hotel

2.5 out of 5
120 Taos St Slidell LA
  • 38 min drive from Crosby Arboretum
Book a stay at this business-friendly hotel in Slidell. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,000 reviews)
"We have stayed here several times before leaving on a cruise out of New Orleans. Great location , clean and a good breakfast. All was great!"

Reviewed on Jun 16, 2026

Best Western Slidell Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Picayune

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Picayune hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Picayune.

Choosing the right hotel in Mississippi has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Picayune’s 1,069 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $69. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Picayune hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Picayune. No matter your reason for visiting Picayune, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Picayune hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Picayune for as low as $69.

How many hotels are there in Picayune?

With over 1,069 hotels in Picayune, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $69.

How to find cheap car rentals in Picayune?

Finding a cheap car rental deal in Picayune is as easy as scoring cheap hotels in Picayune. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.