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Independent in San Francisco

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Featured San Francisco Independent

Hotel Mykonos Panama
Hotel Mykonos Panama
3.5 out of 5
Panamerican Highway, in front of Ruben Cantu Airport, Nuevo Santiago, Veraguas
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star spa hotel in Nuevo Santiago. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Parque Nacional Cerro Hoya and Cerámica ...
Hotel Mykonos Panama
Hotel Gran David
Hotel Gran David
3.5 out of 5
Vía Interamericana, Santiago, Veraguas
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Hotel Gran David
Hotel Galería
Hotel Galería
3 out of 5
Vía Interamericana Santiago, Km 232.88, Nuevo Santiago
Fully refundable
Stay at this 3-star business-friendly hotel in Nuevo Santiago. Enjoy free WiFi, free parking, and 2 outdoor pools. Popular attractions Plaza Banconal and Parque ...
Hotel Galería
HOTEL VISTA LAGO
HOTEL VISTA LAGO
3 out of 5
Rincón Largo, La Pena, Santiago de Veraguas
Stay at this 3-star hotel in La Pena. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Parque Acuatico Italia Guadalupe Panama and Omar ...
HOTEL VISTA LAGO
Hotel Plaza
Hotel Plaza
3 out of 5
Interamericana, Nuevo Santiago, Veraguas
Stay at this 3-star business-friendly hotel in Nuevo Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Parque Nacional ...
Hotel Plaza
Hotel Anachoreo
Hotel Anachoreo
3 out of 5
Calle Chinita, Santa Fe, Veraguas Province
Fully refundableReserve now, pay when you stay
Stay at this 3-star B&B in Santa Fe. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Town Square and Catholic Church of Santa Fe are located ...
Hotel Anachoreo
La Qhia Eco Retreat
La Qhia Eco Retreat
2.5 out of 5
Barriada el Cerro A 100 Mts De, Santa Fe, Veraguas
Stay at this hostal in Santa Fe. Enjoy free parking, breakfast (surcharge), and onsite spa services. Popular attractions Town Square and Catholic Church of Santa ...
La Qhia Eco Retreat
Residencial Camino del Sol
Residencial Camino del Sol
2.5 out of 5
Calle 10ma, Santiago, Panama
Stay at this hotel in Santiago. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Omar Torrijos Herrera Stadium and Plaza Banconal ...
Residencial Camino del Sol
Hotel La Hacienda
Hotel La Hacienda
3 out of 5
Via Interamericana, Rodrigo Luque, Veraguas
Stay at this 3-star family-friendly hotel in Rodrigo Luque. Enjoy free WiFi, free parking, and a casino. Popular attractions Parque Acuatico Italia Guadalupe ...
Hotel La Hacienda
Hostal Travelers
Hostal Travelers
2 out of 5
Santiago de Veraguas, Paso las Tablas, Santiago, Veraguas
Stay at this hostal in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Omar Torrijos Herrera Stadium and Plaza Banconal ...
Hostal Travelers
Hostel Bulaba
Hostel Bulaba
2.5 out of 5
Santa Fe (Centro) calle el Pantano, 2da casa mano izquierd, Santa Fe, Provincia de Veraguas
Stay at this hostal in Santa Fe. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Town Square and Catholic Church of Santa Fe are located ...
Hostel Bulaba
Rainforest Yasmin Hotel
Rainforest Yasmin Hotel
2.5 out of 5
Veraguas, Santa Fe, Provincia de Veraguas
Stay at this hotel in Santa Fe. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Town Square and Catholic Church of Santa Fe are ...
Rainforest Yasmin Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Independent hotels in San Francisco

You’ve already taken the guesswork out of your next vacation. You know you want a Independent hotel in San Francisco. What can you say? You like their style, they’re in a good part of San Francisco, and they never let you down. New bar in town? You’re the first one to check it out. Spiciest item on the menu? You can take the heat. But even the best gamblers hedge their bets. No matter how crazy good your trip is, you want something familiar waiting for you at the end of the day.

All in a name

We all have favorites. There’s nothing wrong with knowing what you like. You like to stay at Independent near , San Francisco to do the tourist thing (because sometimes it is fun) and then hit up the places that aren’t on the map. And no matter what fun you get into, you have Independent hotels with their comfy beds and thoughtful amenities waiting to tuck you in.

As you like it

Have a price you want to stick to, so you can paint the town red? Maybe, it’s all about the hotel features. Who couldn’t use a hot tub? Pick your pleasure by:

  • Hotwire Hot Rate: Grab the Independent hotel in San Francisco at an absolute steal. After you book it, we’ll tell you the hotel name. You might nab that 4-star hotel for a 2-star price.
  • Price: How low can we go? Quite low in fact. Check out our prices per night, starting at $74.
  • Amenities: Grab a cocktail at the lounge and maybe wander upstairs to the rooftop terrace—all the stuff that makes a great vacay.

You’ve already done the hard part—figuring out where you want to stay. Now it’s time to use the money you saved to let the real fun begin. Underground shows? Off-beat attractions? Rooftop escapes? The choice is yours. The only thing wonderfully predictable about this trip is the Independent room you’ll be staying in.