Hotels Near
Santa Cruz

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Featured Santa Cruz Hotels

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

5 out of 5
San Fernando 2 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Seville. Enjoy 2 restaurants, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (1,000 reviews)
"The breakfast bar offered a nice selection of foods. For dinner, I had the best Flan I’ve ever eaten"

Reviewed on May 17, 2026

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
Hotel Murillo

Hotel Murillo

2 out of 5
Calle Lope de Rueda, 7-9 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this family-friendly hotel in Seville. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,009 reviews)
"La terrasse sur le toit était très charmante. Le petit déjeuner offert est excellent et très varié."

Reviewed on May 27, 2026

Hotel Murillo
Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

4 out of 5
Calle Santa Maria La Blanca 5 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Seville. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,004 reviews)
"A beautiful unique Hotel in the heart of the old town area of Seville. Short walk to Cathedral & lovely restaurants and bars - could not fault the facilities and staff and vibe of the Hotel, will definitely return..."

Reviewed on May 31, 2026

Las Casas de la Judería, Sevilla Historic City Center
Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

4 out of 5
Calle Farnesio 6 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this boutique hotel in Seville. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the breakfast and the bar in ...
9.6/10 Exceptional! (1,221 reviews)
"Nice stay in the heart of the city. Old building transformed with Musical decor. Very attentive staff. Nice breakfast. Clean and comfortable. We did not drive. That could be a challenge, but I did see a parking garage next door. Not sure if affiliated"

Reviewed on May 30, 2026

Hotel Amadeus Sevilla
Hotel Fernando III

Hotel Fernando III

4 out of 5
San Jose 21 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the breakfast and the pool ...
9.6/10 Exceptional! (1,504 reviews)
"Food and hotel room were excellent. Staff were friendly and helpful. Pool felt inaccessible as sunbeds were being hogged all day long by certain guests making use of the actual pool difficult. Signposting for the gym could also be better."

Reviewed on May 29, 2026

Hotel Fernando III
Hotel Rey Alfonso X

Hotel Rey Alfonso X

4 out of 5
Calle Ximenez De Enciso, 35 Seville Seville
Fully refundableReserve now, pay when you stay
Stay at this hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.6/10 Exceptional! (1,192 reviews)
"This hotel was exceptional to stay at. The room was extremely clean and well maintained and the location was absolutely perfect. The staff were fabulous and extremely helpful."

Reviewed on May 29, 2026

Hotel Rey Alfonso X
Hotel Murillo Reinoso

Hotel Murillo Reinoso

2 out of 5
Lope de Rueda, 16 Seville Seville
Fully refundableReserve now, pay when you stay
Stay at this hotel in Seville. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the property condition ...
9.6/10 Exceptional! (140 reviews)
"Pillows were a bit too flat for my liking."

Reviewed on May 30, 2026

Hotel Murillo Reinoso
Hotel Doña Maria

Hotel Doña Maria

4 out of 5
Don Remondo 19 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this historic hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,003 reviews)
"We had a wonderful stay. The only thing negative I could say is one of the ladies at the reception desk was rude when we asked how to turn the lights on. It was our first time in Spain so we were not familiar with using a key card for the lights. This wasn’t explained to us at check-in and when we ..."

Reviewed on May 28, 2026

Hotel Doña Maria
Petit Palace Santa Cruz

Petit Palace Santa Cruz

4 out of 5
Munoz y Pabón 18 Seville Seville
Fully refundableReserve now, pay when you stay
Stay at this hotel in Seville. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,003 reviews)
"Incredibly well positioned hotel deep in some of Seville’s smallest streets and avenues. Great sized rooms that were kept very clean. The staff were always friendly and happy to help. Only minor criticism is that there’s nowhere really to sit comfortably in the reception area but you should be out ..."

Reviewed on May 28, 2026

Petit Palace Santa Cruz
EME Catedral Mercer Hotel

EME Catedral Mercer Hotel

5 out of 5
Calle Alemanes 27 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Seville. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,000 reviews)
"I arrived a bit early due to my flight , because I was working remotely, I needed to find a place to plug into Wi-Fi. The steps for accommodating and giving me a very nice space so that I can work remotely until my room was ready.!! I am so thankful for all the attention they gave me. My day was ..."

Reviewed on May 26, 2026

EME Catedral Mercer Hotel
Hotel Boutique Casa del Poeta Sevilla

Hotel Boutique Casa del Poeta Sevilla

4 out of 5
Don Carlos Alonso Chaparro 3 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this boutique hotel in Seville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (927 reviews)
"We were made so welcome and had a fantastic stay. Lovely staff and a charming hotel."

Reviewed on May 31, 2026

Hotel Boutique Casa del Poeta Sevilla
Hotel Doña Lina

Hotel Doña Lina

2 out of 5
Calle Gloria 7 Seville Seville
Fully refundableReserve now, pay when you stay
Stay at this hotel in Seville. Enjoy free WiFi, a rooftop terrace, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (278 reviews)
"Excellent location next to the Alcazar. No breakfast in hotel."

Reviewed on May 29, 2026

Hotel Doña Lina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santa Cruz

Seville is a city that has a lot going on, but you have your sights set on Santa Cruz. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Santa Cruz has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Santa Cruz hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Seville so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Santa Cruz underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Santa Cruz city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Santa Cruz cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Santa Cruz at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $85
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Santa Cruz hotel you want, book it, and never look back. Because your great escape is ahead of you.