Hotels NearSanta Cruz
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Featured Santa Cruz Hotels

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
"The breakfast bar offered a nice selection of foods. For dinner, I had the best Flan I’ve ever eaten"
Reviewed on May 17, 2026

Hotel Murillo
"La terrasse sur le toit était très charmante. Le petit déjeuner offert est excellent et très varié."
Reviewed on May 27, 2026

Las Casas de la Judería, Sevilla Historic City Center
"Hotel was ideally located in the historic part of the city . It was unique with its tunnel access to rooms and internal courtyards added to its charm. It had a calm peaceful air that didn’t reflect its central location. Staff very helpful and charming. The roof top pool was a delightful place to ..."
Reviewed on Jun 1, 2026

Hotel Amadeus Sevilla
"Nice stay in the heart of the city. Old building transformed with Musical decor. Very attentive staff. Nice breakfast. Clean and comfortable. We did not drive. That could be a challenge, but I did see a parking garage next door. Not sure if affiliated"
Reviewed on May 30, 2026

Hotel Fernando III
"Food and hotel room were excellent. Staff were friendly and helpful. Pool felt inaccessible as sunbeds were being hogged all day long by certain guests making use of the actual pool difficult. Signposting for the gym could also be better."
Reviewed on May 29, 2026

Hotel Rey Alfonso X
"This hotel was exceptional to stay at. The room was extremely clean and well maintained and the location was absolutely perfect. The staff were fabulous and extremely helpful."
Reviewed on May 29, 2026

Hotel Murillo Reinoso
"Pillows were a bit too flat for my liking."
Reviewed on May 30, 2026

Hotel Doña Maria
"We had a wonderful stay. The only thing negative I could say is one of the ladies at the reception desk was rude when we asked how to turn the lights on. It was our first time in Spain so we were not familiar with using a key card for the lights. This wasn’t explained to us at check-in and when we ..."
Reviewed on May 28, 2026

Petit Palace Santa Cruz
"Incredibly well positioned hotel deep in some of Seville’s smallest streets and avenues. Great sized rooms that were kept very clean. The staff were always friendly and happy to help. Only minor criticism is that there’s nowhere really to sit comfortably in the reception area but you should be out ..."
Reviewed on May 28, 2026

EME Catedral Mercer Hotel
"I arrived a bit early due to my flight , because I was working remotely, I needed to find a place to plug into Wi-Fi. The steps for accommodating and giving me a very nice space so that I can work remotely until my room was ready.!! I am so thankful for all the attention they gave me. My day was ..."
Reviewed on May 26, 2026

Hotel Boutique Casa del Poeta Sevilla
"We were made so welcome and had a fantastic stay. Lovely staff and a charming hotel."
Reviewed on May 31, 2026

Hotel Doña Lina
"Excellent location next to the Alcazar. No breakfast in hotel."
Reviewed on May 29, 2026
Hotels in Santa Cruz
Seville is a city that has a lot going on, but you have your sights set on Santa Cruz. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Santa Cruz has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Santa Cruz hotels that will do the trick.
A beautiful day in the neighborhood
As much as you like getting out there, it’s also good to know a part of Seville so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Santa Cruz underground. What’s a journey without a good story to go with it?
Beyond the block
We’re not talking about the Santa Cruz city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Santa Cruz cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:
- Hotwire Hot Rate: Snag some of the best hotels in Santa Cruz at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
- Price: You have a price in mind, and we have solutions. Hotels start as low as $85
- Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.
Find the Santa Cruz hotel you want, book it, and never look back. Because your great escape is ahead of you.
- Top Hotels by Star Rating
- More Hotel Options
- Popular Neighborhoods
- Hotels Near Top Attractions
- Nearby Cities
Hotels by Star Rating
More Hotel Options in Santa Cruz
- Historic Hotels in Santa Cruz
- Family Hotels in Santa Cruz
- Apartment Hotel in Santa Cruz
- Romantic Hotels in Santa Cruz
- Boutique Hotels in Santa Cruz
- Luxury Hotels in Santa Cruz
- Pet-friendly Hotels in Santa Cruz
- Hotels with a Pool in Santa Cruz
- Hotels with smoking rooms in Santa Cruz
- Resorts & Hotels with Spas in Santa Cruz
Santa Cruz Neighborhoods
Top Attractions in Santa Cruz
- Hotels near Seville Cathedral (0.07 mi)
- Hotels near Royal Alcázar of Seville (0.21 mi)
- Hotels near Giralda Tower (0.04 mi)
- Hotels near University of Seville (0.32 mi)
- Hotels near Santa Cruz Church (0.15 mi)
- Hotels near Murillo Gardens (0.25 mi)
- Hotels near General Archive of the Indies (0.12 mi)
- Hotels near Murillo House (0.16 mi)
- Hotels near Convent of the Incarnation (0.01 mi)
- Hotels near San Telmo Palace (0.4 mi)
- Hotels near Juderia de Sevilla Interpretation Center (0.15 mi)
- Hotels near Baile Flamenco Museum (0.21 mi)
- Hotels near Casa de Salinas Palace (0.13 mi)
- Hotels near Casa del Flamenco Theater (0.16 mi)
- Hotels near Los Pinelo House (0.13 mi)
- Hotels near Triunfo Plaza (0.05 mi)
- Hotels near Hospital de los Venerables (0.13 mi)
- Hotels near Archbishop's Palace (0.03 mi)
- Hotels near Libreria Vertice (0.31 mi)
- Hotels near Santa María la Blanca Church (0.24 mi)
Cities near Santa Cruz
- Seville Hotels (0.02 mi)
- San Juan de Aznalfarache Hotels (2.97 mi)
- Costa de la Luz Hotels (26.78 mi)
- Carmona Hotels (20.09 mi)
- Bormujos Hotels (4.39 mi)
- Mairena del Aljarafe Hotels (4.09 mi)
- Paseo de Las Delicias Hotels (0.74 mi)
- Alcala de Guadaira Hotels (8.84 mi)
- Dos Hermanas Hotels (7.8 mi)
- Castilleja de la Cuesta Hotels (3.46 mi)
- Benacazon Hotels (11.45 mi)
- Huevar del Aljarafe Hotels (15.79 mi)
- Camas Hotels (2.44 mi)
- Utrera Hotels (18.14 mi)
- European Union Hotels (1312.11 mi)
- Sanlucar la Mayor Hotels (11.51 mi)
- Guillena Hotels (11.41 mi)
- Salteras Hotels (6.94 mi)
- Tomares Hotels (2.99 mi)
- Valencina de la Concepcion Hotels (5.08 mi)
