Hotels Near
Santa Cruz

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking!


Featured Santa Cruz Hotels

Las Casas de la Juderia

Las Casas de la Juderia

4 out of 5
Calle Santa Maria La Blanca 5, Seville, Seville
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Seville. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the bar in our reviews. Popular ...
9.2/10 Wonderful! (1,004 reviews)
"A charming hotel whose rooms are connected homes in the old part of Seville. Access for some is through long underground tunnels with stone floors and walls. The rooms are large and spacious, with classical furniture. This is no problem and to be expected in this unique hotel, located in the heart ..."

Reviewed on Jul 6, 2025

Las Casas de la Juderia
Hotel Rey Alfonso X

Hotel Rey Alfonso X

4 out of 5
Calle Ximenez De Enciso, 35, Seville, Seville
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.4/10 Exceptional! (1,024 reviews)
"Staff was helpful and always there for us. Ines was a wonderful host. Always smiling. Hey Ines, keep up the good work. See you next time. Alvaro & Nilda"

Reviewed on Jul 14, 2025

Hotel Rey Alfonso X
Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

4 out of 5
Calle Farnesio 6, Seville, Seville
Fully refundableReserve now, pay when you stay
Stay at this 4-star boutique hotel in Seville. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the breakfast and the bar in ...
9.6/10 Exceptional! (1,006 reviews)
"Nice property close to but away from the busy square."

Reviewed on Jul 11, 2025

Hotel Amadeus Sevilla
Hotel Fernando III

Hotel Fernando III

4 out of 5
San Jose 21, Seville, Seville
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (1,511 reviews)
"Excellent location close enough to all the important sights without any disturbance from the streets. All members of the staff are very professional and extremely courteous. The only change required is more shade provision for the lovely roof top poo But would definitely stay here again"

Reviewed on Jul 10, 2025

Hotel Fernando III
Hotel Murillo

Hotel Murillo

2 out of 5
Calle Lope de Rueda, 7-9, Seville, Seville
Fully refundable
Book a stay at this family-friendly hotel in Seville. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,004 reviews)
Great location. Avoid arriving at night.
"Loved how central the hotel is, right in the heart of Seville. Few steps away from the cathedral, cafes, shops right outside the hotel. Just make sure to arrive in the day as it is difficult to find at night. Parking is not on site and there is a public parking space not too far away but can be tricky ..."

Reviewed on Jul 12, 2025

Hotel Murillo
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

5 out of 5
San Fernando 2, Seville, Seville
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Seville. Enjoy 2 restaurants, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (992 reviews)
"Giovani was wonderful! Concierge desk was also excellent. Breakfast was superior."

Reviewed on Jun 21, 2025

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
Legado Alcázar Hotel

Legado Alcázar Hotel

4 out of 5
Calle Mariana de Pineda, 18, Seville, Sevilla
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in Seville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful staff in our ...
9.6/10 Exceptional! (875 reviews)
"Tout a été parfait du début à la fin de notre séjour. Mention particulière pour le personnel à l'accueil qui offrait un service exceptionnel."

Reviewed on Jul 5, 2025

Legado Alcázar Hotel
Hotel Doña Maria

Hotel Doña Maria

4 out of 5
Don Remondo 19, Seville, Seville
Fully refundableReserve now, pay when you stay
Stay at this 4-star historic hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the bar and the helpful staff in our ...
8.8/10 Excellent! (996 reviews)
"Loved everything about this property. Everything was perfect"

Reviewed on Jul 12, 2025

Hotel Doña Maria
EME Catedral Mercer Hotel

EME Catedral Mercer Hotel

5 out of 5
Calle Alemanes 27, Seville, Seville
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Seville. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (991 reviews)
"Excellent stay!!"

Reviewed on Jul 12, 2025

EME Catedral Mercer Hotel
Petit Palace Santa Cruz

Petit Palace Santa Cruz

4 out of 5
Munoz y Pabón 18, Seville, Seville
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Seville. Enjoy free WiFi, breakfast (surcharge), and free bicycles on site. Our guests praise the helpful staff ...
8.8/10 Excellent! (956 reviews)
"The service of Amira was wonderful, she was very kind and helpful. The breakfast was delicious. Front desk staff was very nice and friendly."

Reviewed on Jul 12, 2025

Petit Palace Santa Cruz
El Rey Moro Hotel Boutique

El Rey Moro Hotel Boutique

4 out of 5
Reinoso, 8, Seville, Seville
Fully refundableReserve now, pay when you stay
Stay at this 4-star luxury hotel in Seville. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (854 reviews)
"I had an exceptional stay and must give a shoutout to the outstanding service provided by the staff. I will definitely be visiting again and highly recommend El Rey Moro."

Reviewed on Jun 24, 2025

El Rey Moro Hotel Boutique
Hotel Doña Lina

Hotel Doña Lina

2 out of 5
Calle Gloria 7, Seville, Seville
Stay at this hotel in Seville. Enjoy free WiFi, a rooftop terrace, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.4/10 Very Good! (186 reviews)
Excellent location, decent in-room amenities
"The staff was very welcoming and room amenities were very adequate. Rooms are a little small, but considering the location (it’s right behind the Alcázar), quite understandable."

Reviewed on Jul 12, 2025

Hotel Doña Lina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santa Cruz

Seville is a city that has a lot going on, but you have your sights set on Santa Cruz. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Santa Cruz has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Santa Cruz hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Seville so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Santa Cruz underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Santa Cruz city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Santa Cruz cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Santa Cruz at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $56
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Santa Cruz hotel you want, book it, and never look back. Because your great escape is ahead of you.