Hotels Near
Santa Cruz

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Featured Santa Cruz Hotels

Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

4 out of 5
Calle Santa Maria La Blanca 5 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Seville. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,001 reviews)
staff were very courteous and happy to help with any and all requests. The hotel is quite charming and scenic, which I loved about it. only downside was, i think the heat in my room wasn’t working. but i was too lazy to ask about it; im sure they would have either fixed it or changed my room. The ...

Reviewed on Dec 20, 2025

Las Casas de la Judería, Sevilla Historic City Center
Hotel Fernando III

Hotel Fernando III

4 out of 5
San Jose 21 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the breakfast and the pool ...
9.6/10 Exceptional! (1,528 reviews)
The whole hotel was spotless and the staff were so friendly. Location to historical centre in only minutes away on foot but also with good choices on same street as hotel for food and drinks.

Reviewed on Dec 10, 2025

Hotel Fernando III
Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

4 out of 5
Calle Farnesio 6 Seville Seville
Book a stay at this boutique hotel in Seville. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the breakfast and the bar in ...
9.6/10 Exceptional! (1,090 reviews)
Everything was great The service was great. The rooms were clean and the location was great.

Reviewed on Dec 21, 2025

Hotel Amadeus Sevilla
Hotel Rey Alfonso X

Hotel Rey Alfonso X

4 out of 5
Calle Ximenez De Enciso, 35 Seville Seville
Stay at this hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.4/10 Exceptional! (1,117 reviews)
El hotel muy limpio y moderno y el staff muy amable y servicial. Llegamos antes de la hora del check-in y muy amablemente nos guardaron nuestro equipaje. La habitación espaciosa e impecable. Adicional, nos regalaron una botella de Cava ❤️ También nos asistieron a coordinar la transportación hacia ...

Reviewed on Dec 17, 2025

Hotel Rey Alfonso X
Hotel Murillo

Hotel Murillo

2 out of 5
Calle Lope de Rueda, 7-9 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this family-friendly hotel in Seville. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,003 reviews)
Staff was very friendly, perfect location can’t get any better than this hotel

Reviewed on Dec 10, 2025

Hotel Murillo
Petit Palace Santa Cruz

Petit Palace Santa Cruz

4 out of 5
Munoz y Pabón 18 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Seville. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
9/10 Wonderful! (958 reviews)
Very good central position. Friendly helpful staff. Everywhere very clean. Comfortable beds.

Reviewed on Dec 13, 2025

Petit Palace Santa Cruz
Hotel Boutique Casa del Poeta Sevilla

Hotel Boutique Casa del Poeta Sevilla

4 out of 5
Don Carlos Alonso Chaparro 3 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this boutique hotel in Seville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (863 reviews)
The hotel was centrally located and The staff was a pleasure and informative . The room was spacious and clean .. perfect overnight stay

Reviewed on Dec 14, 2025

Hotel Boutique Casa del Poeta Sevilla
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

5 out of 5
San Fernando 2 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Seville. Enjoy 2 restaurants, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (993 reviews)
Phenomenal experience. Finest hotel I’ve ever stayed in by a good measure. Staff went extra mile to help. Stunning facilities, location cannot be bettered.

Reviewed on Dec 13, 2025

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
Suites Murillo Catedral

Suites Murillo Catedral

3.5 out of 5
Calle Segovias, 2 Seville
Fully refundableReserve now, pay when you stay
Stay at this aparthotel in Seville. Enjoy free WiFi, a rooftop terrace, and daily housekeeping. Our guests praise the helpful staff and the clean rooms in our ...
9.4/10 Exceptional! (627 reviews)
It’s a Hotel but it’s felt like I was in home. As an extra there was a washing machine for our room. All of the mini bar was included.

Reviewed on Nov 30, 2025

Suites Murillo Catedral
Hotel Doña Maria

Hotel Doña Maria

4 out of 5
Don Remondo 19 Seville Seville
Book a stay at this historic hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (995 reviews)
Clean room. Friendly and helpful staff. Very central and lovely historic building

Reviewed on Dec 15, 2025

Hotel Doña Maria
EME Catedral Mercer Hotel

EME Catedral Mercer Hotel

5 out of 5
Calle Alemanes 27 Seville Seville
Book a stay at this luxury hotel in Seville. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (988 reviews)
Great breakfast with a very attentive staff. If we didn’t walk so much while there I probably would have gained weight it was that good.

Reviewed on Dec 4, 2025

EME Catedral Mercer Hotel
Hotel Boutique Corral del Rey by ALUZ Collection

Hotel Boutique Corral del Rey by ALUZ Collection

3 out of 5
Calle Corral Del Rey 12 Seville Seville
Fully refundable
Book a stay at this historic hostal in Seville. Enjoy free breakfast, free WiFi, and room service. Popular attractions Giralda Tower and Metropol Parasol are ...
9.6/10 Exceptional! (95 reviews)
Staff was extremely helpful and always very pleasant.

Reviewed on Dec 11, 2025

Hotel Boutique Corral del Rey by ALUZ Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santa Cruz

Seville is a city that has a lot going on, but you have your sights set on Santa Cruz. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Santa Cruz has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Santa Cruz hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Seville so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Santa Cruz underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Santa Cruz city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Santa Cruz cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Santa Cruz at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $72
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Santa Cruz hotel you want, book it, and never look back. Because your great escape is ahead of you.