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Choose from 459 Semmes Hotel Deals

The Admiral, Downtown Historic District

The Admiral, Downtown Historic District

4 out of 5
251 Government Street Mobile AL
  • 31 min drive from Semmes Health Center
Stay at this hotel in Mobile. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in ...
9.4/10 Exceptional! (1,063 reviews)
This hotel is exactly as advertised! Vallet parking and check-in was fast with excellent customer service. Le Moyne’s Chophouse was top tier! I will definitely be coming back in the coming months to enjoy another stay.

Reviewed on Mar 27, 2026

The Admiral, Downtown Historic District
Fairfield Inn & Suites by Marriott Mobile Daphne/ E Shore

Fairfield Inn & Suites by Marriott Mobile Daphne/ E Shore

3 out of 5
12000 Cypress Way Spanish Fort AL
  • 48 min drive from Semmes Health Center
Book a stay at this business-friendly hotel in Spanish Fort. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,006 reviews)
I liked the clean hotel - staff

Reviewed on Mar 26, 2026

Fairfield Inn & Suites by Marriott Mobile Daphne/ E Shore
Courtyard by Marriott Mobile Daphne/Eastern Shore

Courtyard by Marriott Mobile Daphne/Eastern Shore

3 out of 5
13000 Cypress Way Spanish Fort AL
  • 48 min drive from Semmes Health Center
Book a stay at this business-friendly hotel in Spanish Fort. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9/10 Wonderful! (1,002 reviews)
the hotel is clean, convenient, and with all amenities we needed.

Reviewed on Mar 25, 2026

Courtyard by Marriott Mobile Daphne/Eastern Shore
Best Western Plus Mobile Inn & Suites

Best Western Plus Mobile Inn & Suites

2.5 out of 5
600 W I65 Service Rd S Mobile AL
  • 23 min drive from Semmes Health Center
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (645 reviews)
Breakfast was fantastic!!!!

Reviewed on Mar 28, 2026

Best Western Plus Mobile Inn & Suites
Renaissance Mobile Riverview Plaza Hotel

Renaissance Mobile Riverview Plaza Hotel

3.5 out of 5
64 S Water St Mobile AL
  • 32 min drive from Semmes Health Center
Book a stay at this business-friendly hotel in Mobile. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,001 reviews)
We enjoyed this beautiful hotel! The staff was very professional and helpful. Our room was a corner on the 6th floor so, though it was beautiful we heard the traffic below and the train that went through the Convention center across the street.

Reviewed on Mar 28, 2026

Renaissance Mobile Riverview Plaza Hotel
Hampton Inn & Suites Mobile I-65@ Airport Blvd

Hampton Inn & Suites Mobile I-65@ Airport Blvd

3 out of 5
1028 W I-65 Service Rd S Mobile AL
  • 24 min drive from Semmes Health Center
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (1,002 reviews)
It was good, staff was nice.

Reviewed on Mar 26, 2026

Hampton Inn & Suites Mobile I-65@ Airport Blvd
Hilton Garden Inn Mobile East Bay / Daphne

Hilton Garden Inn Mobile East Bay / Daphne

3 out of 5
29546 N Main St Daphne AL
  • 49 min drive from Semmes Health Center
Stay at this hotel in Daphne. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
9/10 Wonderful! (1,003 reviews)
The hotel lobby was very inviting and the staff was friendly. If you were there on business the lobby had several intimate seating areas to meet. We were there for leisure. The pool was heated and clean. The rooms were comfortable and clean. The only negative was the breakfast. There is a fee of ...

Reviewed on Mar 28, 2026

Hilton Garden Inn Mobile East Bay / Daphne
Holiday Inn Express & Suites Mobile West I-10 by IHG

Holiday Inn Express & Suites Mobile West I-10 by IHG

2.5 out of 5
5190 Motel Court Mobile AL
  • 34 min drive from Semmes Health Center
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (1,001 reviews)
Was a very nice place to stay for a very good price. Breakfast was awesome

Reviewed on Mar 25, 2026

Holiday Inn Express & Suites Mobile West I-10 by IHG
Springhill Suites Mobile

Springhill Suites Mobile

3 out of 5
3655 Springhill Memorial Drive Mobile AL
  • 23 min drive from Semmes Health Center
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (883 reviews)
Our stay was great. Clean, felt safe.

Reviewed on Mar 24, 2026

Springhill Suites Mobile
Quality Inn & Suites at Airport Blvd I-65

Quality Inn & Suites at Airport Blvd I-65

2.5 out of 5
150 W I-65 Service Road Mobile AL
  • 23 min drive from Semmes Health Center
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Mobile Cruise Terminal and Herndon ...
7.8/10 Good! (295 reviews)
Staff

Reviewed on Mar 28, 2026

Quality Inn & Suites at Airport Blvd I-65
Stay Express Inn & Suites - Mobile AL

Stay Express Inn & Suites - Mobile AL

2.5 out of 5
5170 Motel Ct Mobile AL
  • 34 min drive from Semmes Health Center
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Westgate Plaza and Boykin Park ...
7.8/10 Good! (336 reviews)
I can only speak for room 216 as that was the room I stayed in. There were more non-working light bulbs than working. The tub was so slow to drain that I thought I was taking a bath instead of a shower, the desk chair appeared to have melted chocolate or something else in it, the other chair was ...

Reviewed on Mar 27, 2026

Stay Express Inn & Suites - Mobile AL
Hilton Garden Inn Mobile West I-65/Airport Blvd

Hilton Garden Inn Mobile West I-65/Airport Blvd

3 out of 5
828 W. I-65 Service Road South Mobile AL
  • 23 min drive from Semmes Health Center
Book a stay at this business-friendly hotel in Mobile. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (851 reviews)
Breakfast was great!

Reviewed on Mar 25, 2026

Hilton Garden Inn Mobile West I-65/Airport Blvd
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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