Search for Cheap Deals on
Hotels in Semmes

Check Last Minute Semmes Hotel Deals

Tonight Jun 27 - Jun 28Next weekend Jul 3 - Jul 5

Choose from 488 Semmes Hotel Deals

The Admiral, Downtown Historic District

The Admiral, Downtown Historic District

4 out of 5
251 Government Street Mobile AL
  • 32 min drive from Semmes Library
Stay at this hotel in Mobile. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in ...
9.4/10 Exceptional! (1,213 reviews)
"Nice hotel , staff very friendly bed very comfortable. Bathroom very basic could’ve been upgraded better."

Reviewed on Jun 26, 2026

The Admiral, Downtown Historic District
Quality Inn & Suites at Airport Blvd I-65

Quality Inn & Suites at Airport Blvd I-65

2.5 out of 5
150 W I-65 Service Road Mobile AL
  • 24 min drive from Semmes Library
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Dauphin Street and Mobile Cruise ...
7.8/10 Good! (424 reviews)
"Ok at best. They need to work on their continental breakfast. And what is up about the white bread?"

Reviewed on Jun 27, 2026

Quality Inn & Suites at Airport Blvd I-65
La Quinta Inn & Suites by Wyndham Mobile

La Quinta Inn & Suites by Wyndham Mobile

3 out of 5
3650 Airport Blvd Mobile AL
  • 24 min drive from Semmes Library
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,006 reviews)
"Clean"

Reviewed on Jun 26, 2026

La Quinta Inn & Suites by Wyndham Mobile
Hilton Garden Inn Mobile East Bay / Daphne

Hilton Garden Inn Mobile East Bay / Daphne

3 out of 5
29546 N Main St Daphne AL
  • 49 min drive from Semmes Library
Stay at this hotel in Daphne. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
9/10 Wonderful! (1,005 reviews)
"The pool needed cleaned. Fellow swimmers were told it had just been cleaned but cloudy and very strong chlorine! Perfect stay beyond that and it did not stop my son from swimming!"

Reviewed on Jun 25, 2026

Hilton Garden Inn Mobile East Bay / Daphne
Stay Express Inn & Suites - Mobile AL

Stay Express Inn & Suites - Mobile AL

2.5 out of 5
5170 Motel Ct Mobile AL
  • 35 min drive from Semmes Library
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Westgate Plaza and Boykin Park ...
7.6/10 Good! (434 reviews)
"Had to ask for clean sheets. What’s that saying you get what you pay for."

Reviewed on Jun 23, 2026

Stay Express Inn & Suites - Mobile AL
Fairfield Inn & Suites by Marriott Mobile Daphne/ E Shore

Fairfield Inn & Suites by Marriott Mobile Daphne/ E Shore

3 out of 5
12000 Cypress Way Spanish Fort AL
  • 49 min drive from Semmes Library
Book a stay at this business-friendly hotel in Spanish Fort. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,002 reviews)
"Great location and a very clean property."

Reviewed on Jun 27, 2026

Fairfield Inn & Suites by Marriott Mobile Daphne/ E Shore
Courtyard by Marriott Mobile

Courtyard by Marriott Mobile

3 out of 5
1000 West I-65 Service Road South Mobile AL
  • 25 min drive from Semmes Library
Book a stay at this business-friendly hotel in Mobile. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.2/10 Very Good! (476 reviews)
"Clean and as shown! Staff was friendly and helpful"

Reviewed on Jun 25, 2026

Courtyard by Marriott Mobile
Courtyard by Marriott Mobile Daphne/Eastern Shore

Courtyard by Marriott Mobile Daphne/Eastern Shore

3 out of 5
13000 Cypress Way Spanish Fort AL
  • 49 min drive from Semmes Library
Book a stay at this business-friendly hotel in Spanish Fort. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9/10 Wonderful! (1,003 reviews)
"Loved everything about it"

Reviewed on Jun 26, 2026

Courtyard by Marriott Mobile Daphne/Eastern Shore
Springhill Suites Mobile

Springhill Suites Mobile

3 out of 5
3655 Springhill Memorial Drive Mobile AL
  • 24 min drive from Semmes Library
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (952 reviews)
"The property was old, building really needed to be updated."

Reviewed on Jun 26, 2026

Springhill Suites Mobile
Comfort Suites Daphne - Mobile East Bay

Comfort Suites Daphne - Mobile East Bay

2.5 out of 5
29450 N. Main St Daphne AL
  • 49 min drive from Semmes Library
Book a stay at this business-friendly hotel in Daphne. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,001 reviews)
"Well our room started leaking with all the rain ,and they offered to move us to another room but we were leaving to a condo at orange beach and they refunded our money for that day and was great of them doing that so I will stay there again"

Reviewed on Jun 23, 2026

Comfort Suites Daphne - Mobile East Bay
Hampton Inn & Suites Mobile I-65@ Airport Blvd

Hampton Inn & Suites Mobile I-65@ Airport Blvd

3 out of 5
1028 W I-65 Service Rd S Mobile AL
  • 25 min drive from Semmes Library
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (1,003 reviews)
"The lady at the front desk, when we checked in, was very polite and accommodating. The room was very clean and spacious. The AC worked very well. Breakfast was good. The hotel was easy to access and parking was easy. I would definitely stay here again"

Reviewed on Jun 25, 2026

Hampton Inn & Suites Mobile I-65@ Airport Blvd
Holiday Inn Express & Suites Mobile West I-10 by IHG

Holiday Inn Express & Suites Mobile West I-10 by IHG

2.5 out of 5
5190 Motel Court Mobile AL
  • 35 min drive from Semmes Library
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (1,004 reviews)
"THE SEVING STAFF WAS EXTEMELY RUDE. ON SUNDAY MORNING ONE STAFF TOLD MY WIFE AND ME WE COULD GET ANYTHING THAT WAS ALREADY OUT[ IT WAS EARLY 5- 10 MINUTES SOME PEOPLE WERE ALREADY EATING] I WAS LOOK AT THE SERVING AREA TO SEE WHAT WAS OUT ANOTHER STAFF TOLD ME TO WAIT THAT BREAKFAST DID NOT START ..."

Reviewed on Jun 26, 2026

Holiday Inn Express & Suites Mobile West I-10 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Semmes

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Semmes hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Semmes.

Choosing the right hotel in Alabama has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Semmes’s 488 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $76. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Semmes hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Semmes. No matter your reason for visiting Semmes, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Semmes hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Semmes for as low as $76.

How many hotels are there in Semmes?

With over 488 hotels in Semmes, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $76.

How to find cheap car rentals in Semmes?

Finding a cheap car rental deal in Semmes is as easy as scoring cheap hotels in Semmes. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.