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Semmes

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Semmes Flights as Low as $245

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Tue, Jun 3 - Wed, Aug 6
STL
Lambert-St. Louis Intl.
MOB
Mobile Regional
$245 Roundtrip, found 6 hours ago
$245
Roundtrip
found 6 hours ago
Select Delta flight, departing Tue, Jun 3 from Lambert-St. Louis Intl. to Mobile Regional, returning Wed, Aug 6, priced at $245 found 6 hours ago
Delta
Thu, May 29 - Wed, Aug 6
STL
Lambert-St. Louis Intl.
MOB
Mobile Regional
$246 Roundtrip, found 7 hours ago
$246
Roundtrip
found 7 hours ago
Select Delta flight, departing Thu, May 29 from Lambert-St. Louis Intl. to Mobile Regional, returning Wed, Aug 6, priced at $246 found 7 hours ago
United
Sun, Apr 13 - Sat, Apr 19
STL
Lambert-St. Louis Intl.
MOB
Mobile Regional
$249 Roundtrip, found 2 hours ago
$249
Roundtrip
found 2 hours ago
Select United flight, departing Sun, Apr 13 from Lambert-St. Louis Intl. to Mobile Regional, returning Sat, Apr 19, priced at $249 found 2 hours ago
Delta
Mon, Apr 14 - Sat, Apr 19
STL
Lambert-St. Louis Intl.
MOB
Mobile Regional
$250 Roundtrip, found 2 hours ago
$250
Roundtrip
found 2 hours ago
Select Delta flight, departing Mon, Apr 14 from Lambert-St. Louis Intl. to Mobile Regional, returning Sat, Apr 19, priced at $250 found 2 hours ago
Delta
Fri, Apr 11 - Fri, Apr 18
STL
Lambert-St. Louis Intl.
MOB
Mobile Regional
$251 Roundtrip, found 2 hours ago
$251
Roundtrip
found 2 hours ago
Select Delta flight, departing Fri, Apr 11 from Lambert-St. Louis Intl. to Mobile Regional, returning Fri, Apr 18, priced at $251 found 2 hours ago
Delta
Fri, Apr 11 - Wed, Apr 16
STL
Lambert-St. Louis Intl.
MOB
Mobile Regional
$256 Roundtrip, found 2 hours ago
$256
Roundtrip
found 2 hours ago
Select Delta flight, departing Fri, Apr 11 from Lambert-St. Louis Intl. to Mobile Regional, returning Wed, Apr 16, priced at $256 found 2 hours ago
Delta
Sun, Apr 13 - Sat, Apr 19
STL
Lambert-St. Louis Intl.
MOB
Mobile Regional
$258 Roundtrip, found 2 hours ago
$258
Roundtrip
found 2 hours ago
Select Delta flight, departing Sun, Apr 13 from Lambert-St. Louis Intl. to Mobile Regional, returning Sat, Apr 19, priced at $258 found 2 hours ago
United
Sun, Apr 13 - Sat, Apr 19
STL
Lambert-St. Louis Intl.
MOB
Mobile Regional
$259 Roundtrip, found 2 hours ago
$259
Roundtrip
found 2 hours ago
Select United flight, departing Sun, Apr 13 from Lambert-St. Louis Intl. to Mobile Regional, returning Sat, Apr 19, priced at $259 found 2 hours ago
Delta
Sun, Apr 13 - Sat, Apr 19
STL
Lambert-St. Louis Intl.
MOB
Mobile Regional
$275 Roundtrip, found 2 hours ago
$275
Roundtrip
found 2 hours ago
Select Delta flight, departing Sun, Apr 13 from Lambert-St. Louis Intl. to Mobile Regional, returning Sat, Apr 19, priced at $275 found 2 hours ago
Delta
Fri, Jun 6 - Wed, Aug 6
STL
Lambert-St. Louis Intl.
MOB
Mobile Regional
$276 Roundtrip, found 6 hours ago
$276
Roundtrip
found 6 hours ago
Select Delta flight, departing Fri, Jun 6 from Lambert-St. Louis Intl. to Mobile Regional, returning Wed, Aug 6, priced at $276 found 6 hours ago
Delta
Fri, Apr 4 - Wed, Apr 9
ORF
Norfolk Intl.
MOB
Mobile Regional
$279 Roundtrip, found 1 day ago
$279
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Apr 4 from Norfolk Intl. to Mobile Regional, returning Wed, Apr 9, priced at $279 found 1 day ago
Delta
Wed, Apr 2 - Tue, Apr 8
ORD
O'Hare Intl.
MOB
Mobile Regional
$280 Roundtrip, found 6 days ago
$280
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Apr 2 from O'Hare Intl. to Mobile Regional, returning Tue, Apr 8, priced at $280 found 6 days ago
Delta
Tue, Apr 1 - Tue, Apr 8
MKE
General Mitchell Intl.
MOB
Mobile Regional
$280 Roundtrip, found 2 days ago
$280
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Apr 1 from General Mitchell Intl. to Mobile Regional, returning Tue, Apr 8, priced at $280 found 2 days ago
American Airlines
Sun, Apr 13 - Sat, Apr 19
STL
Lambert-St. Louis Intl.
MOB
Mobile Regional
$280 Roundtrip, found 2 hours ago
$280
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sun, Apr 13 from Lambert-St. Louis Intl. to Mobile Regional, returning Sat, Apr 19, priced at $280 found 2 hours ago
Delta
Tue, May 13 - Tue, May 20
DTW
Detroit Metropolitan Wayne County
MOB
Mobile Regional
$374 Roundtrip, found 2 days ago
$374
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, May 13 from Detroit Metropolitan Wayne County to Mobile Regional, returning Tue, May 20, priced at $374 found 2 days ago
Delta
Sun, Mar 30 - Sat, Apr 5
ATL
Hartsfield-Jackson Atlanta Intl.
MOB
Mobile Regional
$658 Roundtrip, found 3 hours ago
$658
Roundtrip
found 3 hours ago
Select Delta flight, departing Sun, Mar 30 from Hartsfield-Jackson Atlanta Intl. to Mobile Regional, returning Sat, Apr 5, priced at $658 found 3 hours ago

Cheap Flights to Semmes

Fall in love at first flight with your vacation to Semmes by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Semmes on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Semmes, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Semmes

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Semmes with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MOB airport.

What is the cheapest month to fly to Semmes?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Semmes are in June, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Semmes?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Semmes.

What airport is best to fly into Semmes?

When you’re planning your trip to Semmes, convenience is the name of the game. Luckily, Semmes Mobile Regional Airport is nearby so you can deplane and get going on checking off everything on your Semmes must-do list.

How much are flights to Semmes?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Semmes on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $245, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Semmes?

The trick to saving a stack of cash on your flight to Semmes? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $245 right now, why wait?

Semmes Flight Information
Destination airport
Mobile Regional
Destination airport IATA code
MOB
Roundtrip price
$245

Last Minute Hotel Deals in Semmes

The Admiral, Downtown Historic District
The Admiral, Downtown Historic District
4 out of 5
251 Government Street, Mobile, AL
The price is $148 per night from Apr 13 to Apr 14
$148
includes taxes & fees
Apr 13 - Apr 14
Stay at this 4-star hotel in Mobile. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (454 reviews)
"Will definitely stay here everyone I’m in Mobile!!"

Reviewed on Mar 23, 2025

The Admiral, Downtown Historic District
Holiday Inn Mobile-Dwtn/Hist. District by IHG
Holiday Inn Mobile-Dwtn/Hist. District by IHG
3 out of 5
301 Government St, Mobile, AL
The price is $120 per night from Mar 30 to Mar 31
$120
includes taxes & fees
Mar 30 - Mar 31
Stay at this 3-star business-friendly hotel in Mobile. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (1,001 reviews)
"This a great place to stay when going to the Saenger. It's less than a three-block walk. The area was clean, and we felt very safe. The hotel was clean and very comfortable. All of the staff members were very friendly and helpful. Diesha at the front desk was awesome. The lady waiting tables for ..."

Reviewed on Mar 17, 2025

Holiday Inn Mobile-Dwtn/Hist. District by IHG
Hyatt Studios Mobile/Tillmans Corner
Hyatt Studios Mobile/Tillmans Corner
2 out of 5
5195 Motel Ct, Mobile, AL
The price is $96 per night from Apr 18 to Apr 19
$96
includes taxes & fees
Apr 18 - Apr 19
Stay at this hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Westgate Plaza and Boykin Park are located nearby.
9.4/10 Exceptional! (21 reviews)
"The staff was very courteous"

Reviewed on Mar 24, 2025

Hyatt Studios Mobile/Tillmans Corner
Renaissance Mobile Riverview Plaza Hotel
Renaissance Mobile Riverview Plaza Hotel
3.5 out of 5
64 S Water St, Mobile, AL
The price is $184 per night from Apr 12 to Apr 13
$184
includes taxes & fees
Apr 12 - Apr 13
Book a stay at this business-friendly hotel in Mobile. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (999 reviews)
"Went for Mardi Gras ball. Great location since ball was at convention center"

Reviewed on Mar 1, 2025

Renaissance Mobile Riverview Plaza Hotel
Quality Inn & Suites at Airport Blvd I-65
Quality Inn & Suites at Airport Blvd I-65
2.5 out of 5
150 W I-65 Service Road, Mobile, AL
The price is $64 per night from Apr 7 to Apr 8
$64
includes taxes & fees
Apr 7 - Apr 8
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Mobile Cruise Terminal and Herndon ...
7.4/10 Good! (83 reviews)
"It was great staying at the Quality Inn & Suites except for when the Internet went down and I had to use my WiFi from Guam. Also, they need to provide a better breakfast than what they have everyday."

Reviewed on Mar 25, 2025

Quality Inn & Suites at Airport Blvd I-65
Comfort Suites Mobile-South Alabama University Area
Comfort Suites Mobile-South Alabama University Area
2.5 out of 5
80 Springdale Blvd, Mobile, AL
The price is $94 per night from Apr 20 to Apr 21
$94
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this spa hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
7.8/10 Good! (1,001 reviews)
"It was safe and comfortable"

Reviewed on Mar 26, 2025

Comfort Suites Mobile-South Alabama University Area
Fairfield Inn & Suites by Marriott Mobile
Fairfield Inn & Suites by Marriott Mobile
2.5 out of 5
950-A W I-65 Service Road South, Mobile, AL
The price is $97 per night from Apr 14 to Apr 15
$97
includes taxes & fees
Apr 14 - Apr 15
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,002 reviews)
"They made us take our own trash out from our room during our stay. Very few of them smiled. The shower floor was slimy."

Reviewed on Mar 25, 2025

Fairfield Inn & Suites by Marriott Mobile
La Quinta Inn & Suites by Wyndham Mobile
La Quinta Inn & Suites by Wyndham Mobile
2.5 out of 5
3650 Airport Blvd, Mobile, AL
The price is $86 per night from Apr 20 to Apr 21
$86
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (1,001 reviews)
"Would stay again"

Reviewed on Mar 11, 2025

La Quinta Inn & Suites by Wyndham Mobile
See all 443 properties in Semmes
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.