Search Cheap Flights to
Semmes

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Semmes Flights as Low as $265

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Bargain Flight
United
Bargain Flight
Delta
Delta
Delta
American Airlines
American Airlines
Delta
Delta
Delta
Delta
Delta
Delta
Delta
Delta

Cheap Flights to Semmes

Fall in love at first flight with your vacation to Semmes by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Semmes on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Semmes, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Semmes

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Semmes with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MOB airport.

What is the cheapest month to fly to Semmes?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Semmes are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Semmes?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 14 to choose from for your flight to Semmes.

What airport is best to fly into Semmes?

When you’re planning your trip to Semmes, convenience is the name of the game. Luckily, Semmes Mobile Regional Airport is nearby so you can deplane and get going on checking off everything on your Semmes must-do list.

How much are flights to Semmes?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Semmes on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $265, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Semmes?

The trick to saving a stack of cash on your flight to Semmes? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $265 right now, why wait?

Semmes Flight Information
Destination airport
Mobile Regional
Destination airport IATA code
MOB
Roundtrip price
$265

Last Minute Hotel Deals in Semmes

The Admiral, Downtown Historic District

The Admiral, Downtown Historic District

4 out of 5
251 Government Street Mobile AL
Stay at this hotel in Mobile. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in ...
9.4/10 Exceptional! (1,135 reviews)
Great hotel with excellent service, food, drinks and amenities.

Reviewed on May 16, 2026

The Admiral, Downtown Historic District
Renaissance Mobile Riverview Plaza Hotel

Renaissance Mobile Riverview Plaza Hotel

3.5 out of 5
64 S Water St Mobile AL
Book a stay at this business-friendly hotel in Mobile. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,000 reviews)
Clean staff was nice

Reviewed on May 12, 2026

Renaissance Mobile Riverview Plaza Hotel
Courtyard by Marriott Mobile Daphne/Eastern Shore

Courtyard by Marriott Mobile Daphne/Eastern Shore

3 out of 5
13000 Cypress Way Spanish Fort AL
Book a stay at this business-friendly hotel in Spanish Fort. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9/10 Wonderful! (1,004 reviews)
Clean room

Reviewed on May 15, 2026

Courtyard by Marriott Mobile Daphne/Eastern Shore
Fairfield Inn & Suites by Marriott Mobile Daphne/ E Shore

Fairfield Inn & Suites by Marriott Mobile Daphne/ E Shore

3 out of 5
12000 Cypress Way Spanish Fort AL
Book a stay at this business-friendly hotel in Spanish Fort. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,001 reviews)
Love the property and the staff was friendly and helpful. I am mobility-challenged and did not get my requested handicapped room on a low floor. I did get a nice handicapped room on the top floor a very long walk from the elevator. My only other complaint was the free breakfast. There was no meat, ...

Reviewed on May 15, 2026

Fairfield Inn & Suites by Marriott Mobile Daphne/ E Shore
Quality Inn & Suites at Airport Blvd I-65

Quality Inn & Suites at Airport Blvd I-65

2.5 out of 5
150 W I-65 Service Road Mobile AL
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Herndon Park and Dauphin Street ...
7.8/10 Good! (356 reviews)
Great place to stay the night bed was comfy and very quiet for some really good rest

Reviewed on May 14, 2026

Quality Inn & Suites at Airport Blvd I-65
Hilton Garden Inn Mobile East Bay / Daphne

Hilton Garden Inn Mobile East Bay / Daphne

3 out of 5
29546 N Main St Daphne AL
Stay at this hotel in Daphne. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
9/10 Wonderful! (1,001 reviews)
Great stay. Everyone very friendly and helpful

Reviewed on May 15, 2026

Hilton Garden Inn Mobile East Bay / Daphne
Comfort Suites Daphne - Mobile East Bay

Comfort Suites Daphne - Mobile East Bay

2.5 out of 5
29450 N. Main St Daphne AL
Book a stay at this business-friendly hotel in Daphne. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,002 reviews)
The property staff and room were fine the only complaint I have is they took a $100 security deposit and it

Reviewed on May 16, 2026

Comfort Suites Daphne - Mobile East Bay
Hampton Inn & Suites Mobile I-65@ Airport Blvd

Hampton Inn & Suites Mobile I-65@ Airport Blvd

3 out of 5
1028 W I-65 Service Rd S Mobile AL
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (1,002 reviews)
Toilet was running continuously. Loud buzzing sound emitting from ceiling. Sound of traffic was loud. Bed was very uncomfortable- hard as a rock - old. Sheets were very rough - not up to any hotel standard that charges over $150 a night. Pillows not comfortable at all .. like footballs. Breakfast ...

Reviewed on May 14, 2026

Hampton Inn & Suites Mobile I-65@ Airport Blvd
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.