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Hotels in Seneca

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Waterfront Hotel

Waterfront Hotel

3 out of 5
113 S Main St Prairie Du Chien WI
  • 10 hours drive from Mississippi River
Stay at this hotel in Prairie Du Chien. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. ...
9.2/10 Wonderful! (940 reviews)
"Great location when you’re on a motorcycle and can walk into old downtown"

Reviewed on Jun 28, 2026

Waterfront Hotel
Quality Inn & Suites Prairie Du Chien

Quality Inn & Suites Prairie Du Chien

2.5 out of 5
37268 US Highway 18 Prairie Du Chien WI
  • 10 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Prairie Du Chien. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
8.4/10 Very Good! (461 reviews)
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Reviewed on Jun 28, 2026

Quality Inn & Suites Prairie Du Chien
Windsor Place Inn

Windsor Place Inn

2 out of 5
1936 Marquette Road South Prairie Du Chien WI
  • 10 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Prairie Du Chien. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,001 reviews)
"Breakfast could have been better with just a little attention from the staff… tables needed wiped down and out of food with time remaining and staff just sat behind the desk reading a book or playing on phone… on positive note room was extremely clean and quiet"

Reviewed on Jun 25, 2026

Windsor Place Inn
AmericInn by Wyndham Prairie du Chien

AmericInn by Wyndham Prairie du Chien

3 out of 5
37502 Us Highway 35 And 18 S Prairie Du Chien WI
  • 10 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Prairie Du Chien. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (630 reviews)
"Clean room breakfast was good bed hard as a rock"

Reviewed on Jun 28, 2026

AmericInn by Wyndham Prairie du Chien
Country Inn & Suites by Radisson, Prairie du Chien

Country Inn & Suites by Radisson, Prairie du Chien

3 out of 5
1801 Cabela's Lane Prairie Du Chien WI
  • 10 hours drive from Mississippi River
Book a stay at this family-friendly hotel in Prairie Du Chien. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
8.4/10 Very Good! (1,001 reviews)
"Had a wonderful stay! The staff was very accommodating and helpful upon arrival. Would have been nice to have the hot tub open till 11pm."

Reviewed on Jun 27, 2026

Country Inn & Suites by Radisson, Prairie du Chien
AmericInn by Wyndham Boscobel

AmericInn by Wyndham Boscobel

3 out of 5
1700 Elm St Boscobel WI
  • 10 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Boscobel. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (504 reviews)
"This hotel is being remodeled and there’s quite a bit of work going on in the daytime. Some mud and drywall dust in hallways. Service was great and staff was helpful and courteous."

Reviewed on Jun 24, 2026

AmericInn by Wyndham Boscobel
Northwood Inn Prairie Du Chien

Northwood Inn Prairie Du Chien

2 out of 5
1930 S Marquette Rd Prairie Du Chien WI
  • 10 hours drive from Mississippi River
Stay at this hotel in Prairie Du Chien. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Riverside Square and O'Brien Park are located ...
8.4/10 Very Good! (141 reviews)
"We were passing through and looking for a place to stay in Prairie Du Chien . I chose the Northwood Inn based on the many positive reviews and a very reasonable price. It was a very good choice. I would normally expect to pay close to twice the rate at many chain hotels for a room this nice with ..."

Reviewed on Jun 28, 2026

Northwood Inn Prairie Du Chien
Microtel Inn & Suites by Wyndham Prairie du Chien

Microtel Inn & Suites by Wyndham Prairie du Chien

2.5 out of 5
1833 S Marquette Road Prairie Du Chien WI
  • 10 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Prairie Du Chien. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and ...
8.2/10 Very Good! (615 reviews)
"Very nice place but customer service is terrible"

Reviewed on Jun 26, 2026

Microtel Inn & Suites by Wyndham Prairie du Chien
Scenic Valley Motel

Scenic Valley Motel

2 out of 5
1608 Main St Lansing IA
  • 11 hours drive from Mississippi River
Stay at this motel in Lansing. Enjoy free WiFi, free parking, and housekeeping. Popular attractions Mount Hosmer Park and Lansing City Library are located ...
8.2/10 Very Good! (129 reviews)
"Just like a motel should be. You'll definitely get your money's worth."

Reviewed on Jun 21, 2026

Scenic Valley Motel
Prairie Voyager

Prairie Voyager

2.5 out of 5
1010 S Marquette Rd Prairie Du Chien WI
  • 10 hours drive from Mississippi River
Stay at this motel in Prairie Du Chien. Enjoy free WiFi, free parking, and a picnic area. Popular attractions O'Brien Park and Lochner Park are located ...
8.6/10 Excellent! (138 reviews)
"Smoke Alarms went off in the night both of our stays. Otherwise everything else was great."

Reviewed on Jun 28, 2026

Prairie Voyager
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Seneca

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Seneca.

Choosing the right hotel in Wisconsin has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Seneca’s 200 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $72. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Seneca hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Seneca. No matter your reason for visiting Seneca, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Seneca hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Seneca for as low as $72.

How many hotels are there in Seneca?

With over 200 hotels in Seneca, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $72.

How to find cheap car rentals in Seneca?

Finding a cheap car rental deal in Seneca is as easy as scoring cheap hotels in Seneca. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.