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Hotels in De Soto

Choose from 298 De Soto Hotel Deals

Gundersen Hotel & Suites
Gundersen Hotel & Suites
2.5 out of 5
1520 Clinic Court, La Crosse, WI
  • 12 hours drive from Mississippi River
Book a stay at this business-friendly hotel in La Crosse. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,002 reviews)
"The staff were great. Room and facilities are very nice. Breakfast is standard. I was there on a Wednesday night and there were motorcycles racing up and down the road from 1-3AM"

Reviewed on Jul 10, 2025

Gundersen Hotel & Suites
AmericInn by Wyndham Viroqua
AmericInn by Wyndham Viroqua
2.5 out of 5
1325 N Main St, Viroqua, WI
  • 11 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Viroqua. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Viroqua Country Club and Sidie ...
8/10 Very Good! (293 reviews)
"Great stay"

Reviewed on Jul 12, 2025

AmericInn by Wyndham Viroqua
Boarders Inn & Suites by Cobblestone Hotels – Waukon
Boarders Inn & Suites by Cobblestone Hotels – Waukon
3.5 out of 5
407 Rossville Rd, Waukon, IA
  • 10 hours drive from Mississippi River
Stay at this 3.5-star business-friendly hotel in Waukon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (389 reviews)
"Clean and staff was very friendly."

Reviewed on Jul 4, 2025

Boarders Inn & Suites by Cobblestone Hotels – Waukon
MIDWAY MOTEL
MIDWAY MOTEL
2.5 out of 5
850 N Main St, Viroqua, WI
  • 11 hours drive from Mississippi River
Stay at this hotel in Viroqua. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Viroqua Country Club and Sidie Hollow Park are located ...
8.4/10 Very Good! (23 reviews)
"It was clean and it was easy to go to the places that I needed to when we were there."

Reviewed on Jul 9, 2025

MIDWAY MOTEL
Adriatic
Adriatic
2 out of 5
3438 Mormon Coulee Rd, La Crosse, WI
  • 12 hours drive from Mississippi River
Stay at this hotel in La Crosse. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions St. Rose of Viterbo Convent and Mary of the Angels ...
6.8/10 (21 reviews)
"The affordable rate was great."

Reviewed on Jun 22, 2025

Adriatic
Scenic Valley Motel
Scenic Valley Motel
2 out of 5
1608 Main St, Lansing, IA
  • 11 hours drive from Mississippi River
Stay at this motel in Lansing. Enjoy free WiFi, free parking, and housekeeping. Popular attractions Mount Hosmer Park and Lansing City Library are located ...
8.2/10 Very Good! (94 reviews)
"Great little cabin. Really enjoyed our stay. Just wished there was a hot tub."

Reviewed on Jun 30, 2025

Scenic Valley Motel
Welch Motel
Welch Motel
2.5 out of 5
3643 Mormon Coulee Rd., La Crosse, WI
  • 12 hours drive from Mississippi River
Stay at this motel in La Crosse. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.8/10 (240 reviews)
"Slightly outdated, but clean and comfortable. Good hotel for the price."

Reviewed on Jun 22, 2025

Welch Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in De Soto

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Frequently Asked Questions About De Soto hotels

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How many hotels are there in De Soto?

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