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De Soto

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De Soto Flights as Low as $418

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Wed, May 28 - Sat, May 31
AVL
Asheville Regional
LSE
La Crosse Municipal
$418 Roundtrip, found 13 hours ago
$418
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, May 28 from Asheville Regional to La Crosse Municipal, returning Sat, May 31, priced at $418 found 13 hours ago
American Airlines
Wed, May 28 - Sat, May 31
AVL
Asheville Regional
LSE
La Crosse Municipal
$489 Roundtrip, found 13 hours ago
$489
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, May 28 from Asheville Regional to La Crosse Municipal, returning Sat, May 31, priced at $489 found 13 hours ago
American Airlines
Fri, May 30 - Sat, May 31
AVL
Asheville Regional
LSE
La Crosse Municipal
$495 Roundtrip, found 13 hours ago
$495
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Fri, May 30 from Asheville Regional to La Crosse Municipal, returning Sat, May 31, priced at $495 found 13 hours ago
American Airlines
Wed, May 28 - Tue, Jun 3
AVL
Asheville Regional
LSE
La Crosse Municipal
$500 Roundtrip, found 13 hours ago
$500
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, May 28 from Asheville Regional to La Crosse Municipal, returning Tue, Jun 3, priced at $500 found 13 hours ago
American Airlines
Fri, May 30 - Tue, Jun 3
AVL
Asheville Regional
LSE
La Crosse Municipal
$505 Roundtrip, found 13 hours ago
$505
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Fri, May 30 from Asheville Regional to La Crosse Municipal, returning Tue, Jun 3, priced at $505 found 13 hours ago
American Airlines
Tue, May 27 - Sat, May 31
AVL
Asheville Regional
LSE
La Crosse Municipal
$510 Roundtrip, found 13 hours ago
$510
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Tue, May 27 from Asheville Regional to La Crosse Municipal, returning Sat, May 31, priced at $510 found 13 hours ago
American Airlines
Wed, May 28 - Sun, Jun 1
AVL
Asheville Regional
LSE
La Crosse Municipal
$524 Roundtrip, found 13 hours ago
$524
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, May 28 from Asheville Regional to La Crosse Municipal, returning Sun, Jun 1, priced at $524 found 13 hours ago
American Airlines
Fri, May 30 - Sun, Jun 1
AVL
Asheville Regional
LSE
La Crosse Municipal
$529 Roundtrip, found 13 hours ago
$529
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Fri, May 30 from Asheville Regional to La Crosse Municipal, returning Sun, Jun 1, priced at $529 found 13 hours ago
American Airlines
Tue, May 27 - Sun, Jun 1
AVL
Asheville Regional
LSE
La Crosse Municipal
$534 Roundtrip, found 13 hours ago
$534
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Tue, May 27 from Asheville Regional to La Crosse Municipal, returning Sun, Jun 1, priced at $534 found 13 hours ago
American Airlines
Mon, May 26 - Sat, May 31
AVL
Asheville Regional
LSE
La Crosse Municipal
$540 Roundtrip, found 13 hours ago
$540
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Mon, May 26 from Asheville Regional to La Crosse Municipal, returning Sat, May 31, priced at $540 found 13 hours ago
American Airlines
Mon, May 26 - Sun, Jun 1
AVL
Asheville Regional
LSE
La Crosse Municipal
$564 Roundtrip, found 13 hours ago
$564
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Mon, May 26 from Asheville Regional to La Crosse Municipal, returning Sun, Jun 1, priced at $564 found 13 hours ago
American Airlines
Wed, May 28 - Sat, May 31
AVL
Asheville Regional
LSE
La Crosse Municipal
$592 Roundtrip, found 13 hours ago
$592
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, May 28 from Asheville Regional to La Crosse Municipal, returning Sat, May 31, priced at $592 found 13 hours ago
American Airlines
Wed, May 28 - Sat, May 31
AVL
Asheville Regional
LSE
La Crosse Municipal
$620 Roundtrip, found 13 hours ago
$620
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, May 28 from Asheville Regional to La Crosse Municipal, returning Sat, May 31, priced at $620 found 13 hours ago
American Airlines
Wed, May 28 - Sat, May 31
AVL
Asheville Regional
LSE
La Crosse Municipal
$634 Roundtrip, found 13 hours ago
$634
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, May 28 from Asheville Regional to La Crosse Municipal, returning Sat, May 31, priced at $634 found 13 hours ago
American Airlines
Tue, May 27 - Fri, May 30
AVL
Asheville Regional
LSE
La Crosse Municipal
$712 Roundtrip, found 13 hours ago
$712
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Tue, May 27 from Asheville Regional to La Crosse Municipal, returning Fri, May 30, priced at $712 found 13 hours ago
American Airlines
Sat, May 31 - Sat, May 31
AVL
Asheville Regional
LSE
La Crosse Municipal
$728 Roundtrip, found 13 hours ago
$728
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Sat, May 31 from Asheville Regional to La Crosse Municipal, returning Sat, May 31, priced at $728 found 13 hours ago

Cheap Flights to De Soto

Fall in love at first flight with your vacation to De Soto by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to De Soto on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in De Soto, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to De Soto

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to De Soto with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the LSE airport.

What is the cheapest month to fly to De Soto?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to De Soto are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to De Soto?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to De Soto.

What airport is best to fly into De Soto?

When you’re planning your trip to De Soto, convenience is the name of the game. Luckily, De Soto La Crosse Municipal Airport is nearby so you can deplane and get going on checking off everything on your De Soto must-do list.

How much are flights to De Soto?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to De Soto on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $418, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to De Soto?

The trick to saving a stack of cash on your flight to De Soto? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $418 right now, why wait?

De Soto Flight Information
Destination airport
La Crosse Municipal
Destination airport IATA code
LSE
Roundtrip price
$418

Last Minute Hotel Deals in De Soto

Gundersen Hotel & Suites
Gundersen Hotel & Suites
2.5 out of 5
1520 Clinic Court, La Crosse, WI
The price is $206 per night from May 7 to May 8
$206
includes taxes & fees
May 7 - May 8
Book a stay at this business-friendly hotel in La Crosse. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,000 reviews)
"Great place ♡"

Reviewed on Apr 26, 2025

Gundersen Hotel & Suites
Boarders Inn & Suites by Cobblestone Hotels – Waukon
Boarders Inn & Suites by Cobblestone Hotels – Waukon
3.5 out of 5
407 Rossville Rd, Waukon, IA
The price is $100 per night from May 7 to May 8
$100
includes taxes & fees
May 7 - May 8
Stay at this 3.5-star business-friendly hotel in Waukon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (373 reviews)
"Everything was good"

Reviewed on Mar 26, 2025

Boarders Inn & Suites by Cobblestone Hotels – Waukon
AmericInn by Wyndham Viroqua
AmericInn by Wyndham Viroqua
2.5 out of 5
1325 N Main St, Viroqua, WI
The price is $137 per night from May 13 to May 14
$137
includes taxes & fees
May 13 - May 14
Book a stay at this business-friendly hotel in Viroqua. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Fortney Underground Theater and ...
8/10 Very Good! (282 reviews)
"Good location & nice breakfast. Friendly staff."

Reviewed on Apr 30, 2025

AmericInn by Wyndham Viroqua
Welch Motel
Welch Motel
2.5 out of 5
3643 Mormon Coulee Rd., La Crosse, WI
The price is $68 per night from May 7 to May 8
$68
includes taxes & fees
May 7 - May 8
Stay at this motel in La Crosse. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.8/10 (229 reviews)
"Outdated but a place to stay for the price"

Reviewed on Mar 19, 2025

Welch Motel
Scenic Valley Motel
Scenic Valley Motel
2 out of 5
1608 Main St, Lansing, IA
The price is $102 per night from May 7 to May 8
$102
includes taxes & fees
May 7 - May 8
Stay at this motel in Lansing. Enjoy free WiFi, free parking, and housekeeping. Popular attractions Mount Hosmer Park and Lansing City Library are located ...
8/10 Very Good! (83 reviews)
"We were visiting friends in town and just wanted somewhere to lay our heads. Beds were firm but not hard. In our room there were 3 different types of pillows on each bed. Very clean and updated. Easy check in and out Worked perfect for what we needed and the price was great as well"

Reviewed on Jan 31, 2025

Scenic Valley Motel
Adriatic
Adriatic
2 out of 5
3438 Mormon Coulee Rd, La Crosse, WI
The price is $65 per night from Jun 1 to Jun 2
$65
includes taxes & fees
Jun 1 - Jun 2
Stay at this hotel in La Crosse. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions La Crosse Center and St. Rose of Viterbo Convent ...
7.2/10 Good! (14 reviews)
"Very close to my family and quiet"

Reviewed on Apr 24, 2025

Adriatic
MIDWAY MOTEL
MIDWAY MOTEL
2.5 out of 5
850 N Main St, Viroqua, WI
The price is $111 per night from May 22 to May 23
$111
includes taxes & fees
May 22 - May 23
Stay at this hotel in Viroqua. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Fortney Underground Theater and Viroqua Country Club ...
8.8/10 Excellent! (16 reviews)
"It was a wonderful stay. No surprises. I will return."

Reviewed on Apr 6, 2025

MIDWAY MOTEL
See all 294 properties in De Soto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.