Search for Cheap Deals onHotels in Southern Minnesota
Choose from 1162 Southern Minnesota Hotel Deals

AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S, Rochester, MN
Book a stay at this spa hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful staff in our ...
8/10 Very Good! (932 reviews)
"The room was clean & that's what we really look for. Our room could use a couple things fixed but we reserved thru Expedia, that's what you get, one of the block of rooms. The breakfast was the usual, lots to pick from. Staff were great. We ate at the attached restaurant which was convenient & great ..."
Reviewed on Jul 16, 2025

Kahler Grand Hotel
20 2nd Ave Sw, Rochester, MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.2/10 Very Good! (1,450 reviews)
"Always clean, always convenient"
Reviewed on Jul 14, 2025

Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw, Rochester, MN
Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,000 reviews)
Great place to stay at an excellent price!
"We have stayed here often and will continue to do so in the future."
Reviewed on Jul 16, 2025

Spark by Hilton Rochester South
4165 Maine Ave SE, Rochester, MN
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (75 reviews)
"Very nice property, quiet area off the main road through Rochester. Would have been nice if they had more of a patio for outdoor seating. There were a couple tables outside the pool but were taken by several other groups so we made due with some chairs and a bench. There were softball games and pro ..."
Reviewed on Jul 15, 2025

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW, Rochester, MN
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (965 reviews)
"The room was clean and spacious, beds were comfortable and it had a little kitchenette. The parking garage was full, and we had to park on the street where we could see broken bottles and intoxicated people walking around. It wasn’t the safest area to leave a vehicle."
Reviewed on Jul 12, 2025

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw, Rochester, MN
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
7.8/10 Good! (1,367 reviews)
"Location to Mayo"
Reviewed on Jul 11, 2025

Aspen Select
1215 2nd St SW, Rochester, MN
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (1,000 reviews)
"Lots of construction around property! Hard to walk much less drive. Can’t blame hotel for that. Place was different, rooms had glass walls that faced hallways. With curtain drawn no problem. Good restaurant right next door. With low price we paid pretty satisfied."
Reviewed on Jul 14, 2025

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
4353 Canal Pl SE, Rochester, MN
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.2/10 Good! (1,029 reviews)
"bathtub needs updating"
Reviewed on Jul 15, 2025

Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway, Rochester, MN
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and ...
8.8/10 Excellent! (791 reviews)
"Nice place will stay again"
Reviewed on Jul 13, 2025

EVEN Hotel Rochester - Mayo Clinic Area by IHG
101 11TH Avenue SW, Suite A, Rochester, MN
Stay at this 4-star business-friendly hotel in Rochester. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
9.4/10 Exceptional! (850 reviews)
"This is an excellent place to stay for access to St. Mary's and other Mayo Clinic locations. The staff is friendly and helpful and the rooms are very clean. Has workout equipment in room if you're at the Even and you can bring your pet at the Staybridge, what could be better?"
Reviewed on Jul 15, 2025

St James Hotel, a Historic Hotel of America
406 Main St., Red Wing, MN
Stay at this 3.5-star spa hotel in Red Wing. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the comfy rooms in ...
9/10 Wonderful! (1,004 reviews)
Lovely historical hotel!
"This hotel is absolutely stunning and a must-stay when in Red Wing. So much to explore within the building itself. Wonderful on-site restaurant with a patio and weekend music. Within walking distance of everything you need. The complimentary YMCA pass is a plus."
Reviewed on Jul 6, 2025

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
1517 16th St Sw, Rochester, MN
Book a stay at this family-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.2/10 Very Good! (648 reviews)
"Nice place to stay"
Reviewed on Jul 16, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Booked Hotels in Southern Minnesota
- AmericInn by Wyndham Rochester Near Mayo Clinic
- Kahler Grand Hotel
- Med City Inn & Suites - Mayo Clinic Area
- Spark by Hilton Rochester South
- Kahler Inn and Suites - Mayo Clinic Area
- Aspen Select
- La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
- St James Hotel, a Historic Hotel of America
- Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
- SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
- Country Inn & Suites Rochester South Mayo Clinic
- Econo Lodge Mayo Clinic Area
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