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Hotels in Southern Minnesota

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Choose from 1143 Southern Minnesota Hotel Deals

Kahler Grand Hotel
Kahler Grand Hotel
3 out of 5
20 2nd Ave Sw, Rochester, MN
  • 2 min walk from Mayo Clinic
The price is $187 per night from Mar 2 to Mar 3
$187
includes taxes & fees
Mar 2 - Mar 3
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.2/10 Very Good! (1,300 reviews)
excellent location for Mayo Clinic
"Beautiful hotel in amazing location. Restaurants, shops, ease of getting around all plusses. Lobby staff great. Very good bed, everything very clean. Would be a 5 not a 4 if water temp in shower was more consistent, and we hadn't been missed for room/towel refresh one day. Housekeeping did come but ..."

Reviewed on Feb 28, 2025

Kahler Grand Hotel
Med City Inn & Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area
2.5 out of 5
435 16th Ave Nw, Rochester, MN
  • 26 min walk from Mayo Clinic
The price is $92 per night from Mar 2 to Mar 3
$92
includes taxes & fees
Mar 2 - Mar 3
Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,001 reviews)
"The free shuttle to Mayo Clinic was a real plus for us. The staff were very friendly and accomodating."

Reviewed on Feb 19, 2025

Med City Inn & Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
3.5 out of 5
9 3rd Ave Nw, Rochester, MN
  • 3 min walk from Mayo Clinic
The price is $169 per night from Mar 2 to Mar 3
$169
includes taxes & fees
Mar 2 - Mar 3
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
7.6/10 Good! (1,309 reviews)
"I’ve stayed here several times and it is always very nice! Front desk is courteous. Close to the Mayo Clinic for medical appointments. Extremely convenient!"

Reviewed on Feb 25, 2025

Kahler Inn and Suites - Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
3 out of 5
110 Civic Center Drive NW, Rochester, MN
  • 7 min walk from Mayo Clinic
The price is $131 per night from Mar 9 to Mar 10
$131
includes taxes & fees
Mar 9 - Mar 10
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (830 reviews)
"The hospitality here is fantastic. My mother and I loved the soup and the breakfast, and we thought our room was clean and comfortable. We will be staying here again!"

Reviewed on Feb 24, 2025

Hyatt House Rochester/Mayo Clinic Area
AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic
3 out of 5
1625 Broadway Ave S, Rochester, MN
  • 4 min drive from Mayo Clinic
The price is $88 per night from Mar 16 to Mar 17
$88
includes taxes & fees
Mar 16 - Mar 17
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful ...
7.8/10 Good! (732 reviews)
"It was impossible to regulate the temperature in the room. If the thermostat was on heat whether set at 65 or 75 the room temp would jump to 85. Turning the heat off when -20 outside not an option so spent the night adjusting thermostat every 45-60 minutes! Ugh!"

Reviewed on Feb 23, 2025

AmericInn by Wyndham Rochester Near Mayo Clinic
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 out of 5
1517 16th St Sw, Rochester, MN
  • 5 min drive from Mayo Clinic
The price is $108 per night from Mar 16 to Mar 17
$108
includes taxes & fees
Mar 16 - Mar 17
Book a stay at this family-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.2/10 Very Good! (563 reviews)
"Nice, clean property. Only issue is bugs, but that is explainable with the warm weather."

Reviewed on Feb 25, 2025

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Country Inn & Suites by Radisson, Mankato Hotel and Conference Center, MN
Country Inn & Suites by Radisson, Mankato Hotel and Conference Center, MN
3 out of 5
1900 Premier Drive, Mankato, MN
  • 4 hours drive from Mayo Clinic
The price is $112 per night from Mar 9 to Mar 10
$112
includes taxes & fees
Mar 9 - Mar 10
Stay at this 3-star business-friendly hotel in Mankato. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.8/10 Good! (759 reviews)
"Very comfortable. Hwy access nearby."

Reviewed on Feb 24, 2025

Country Inn & Suites by Radisson, Mankato Hotel and Conference Center, MN
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3 out of 5
401 6th St Sw, Rochester, MN
  • 8 min walk from Mayo Clinic
The price is $142 per night from Mar 2 to Mar 3
$142
includes taxes & fees
Mar 2 - Mar 3
Book a stay at this golf hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. ...
8.2/10 Very Good! (1,003 reviews)
"Always friendly staff and quite place to stsy"

Reviewed on Feb 25, 2025

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
3.5 out of 5
220 S Broadway, Rochester, MN
  • 6 min walk from Mayo Clinic
The price is $135 per night from Mar 7 to Mar 8
$135
includes taxes & fees
Mar 7 - Mar 8
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and ...
8.8/10 Excellent! (698 reviews)
"Rooms are clean and neat."

Reviewed on Feb 26, 2025

Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
3 out of 5
1125 2nd St Sw, Rochester, MN
  • 19 min walk from Mayo Clinic
The price is $111 per night from Mar 21 to Mar 22
$111
includes taxes & fees
Mar 21 - Mar 22
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (729 reviews)
"Very Friendly and accommodating Staff. Room was perfect with plenty of room, a nice shower and a comfortable bed. The complimentary fresh baked cookies and variety of beverages available 24 hours at the front desk as well as a great breakfast was a very nice added bonus. I will not hesitate to book ..."

Reviewed on Feb 26, 2025

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
AmericInn by Wyndham Mankato Event Center
AmericInn by Wyndham Mankato Event Center
2.5 out of 5
240 Stadium Road, Mankato, MN
  • 4 hours drive from Mayo Clinic
The price is $106 per night from Mar 2 to Mar 3
$106
includes taxes & fees
Mar 2 - Mar 3
Book a stay at this business-friendly hotel in Mankato. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,001 reviews)
"Guests were very loud in the hallway in the middle of the night. Multiple times. Within earshot of the front desk. Nothing was done about it."

Reviewed on Feb 24, 2025

AmericInn by Wyndham Mankato Event Center
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
2.5 out of 5
4141 Maine Avenue SE, Rochester, MN
  • 10 min drive from Mayo Clinic
The price is $98 per night from Mar 23 to Mar 24
$98
includes taxes & fees
Mar 23 - Mar 24
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,000 reviews)
"Good property"

Reviewed on Feb 23, 2025

Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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