Search for Cheap Deals onHotels in Southern Minnesota
Choose from 1234 Southern Minnesota Hotel Deals
Med City Inn & Suites - Mayo Clinic Area
"Hotel hidden behind Famous Dave’s Restaurant, can’t see from road. Room was clean and generous in size. Notified Staff of late check-in and were accommodating, friendly staff. Reasonable rates and met my needs for an overnight stay. Thank you!"
Reviewed on Oct 10, 2026
Kahler Grand Hotel
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
AmericInn by Wyndham Rochester Near Mayo Clinic
"We had to be"
Reviewed on Oct 8, 2026
Kahler Inn and Suites - Mayo Clinic Area
"Could use many upgrades. Staff lacking on giving information. Breakfast was AWESOME! Parking was handy but there is a daily charge. Rooms were okay but could be cleaner and upgrade."
Reviewed on Oct 10, 2026
Brentwood Inn & Suites
Express Suites Riverport Inn & Suites
"Great place to stay and relax while in Winona"
Reviewed on Oct 10, 2026
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
"The place was not bed it just looked more of a motel than hotel. I just like better. That’s why I gave it that score the breakfast was ok. The staff was wonderful np."
Reviewed on Oct 9, 2026
Hotel Indigo Rochester – Mayo Clinic Area by IHG
"Three different rooms - all had old noisy refrigerators. Unplugged from electrical outlet to get to sleep at night. Breakfast is at market rates - not included. Parking at public ramp located next door is also an extra $16 nightly. Enjoyed free transportation to Mayo Clinic for medical appointments. ..."
Reviewed on Oct 9, 2026
Hyatt House Rochester/Mayo Clinic Area
"The room was very clean. Staff were kind and pleasant upon check in."
Reviewed on Oct 7, 2026
AmericInn by Wyndham Mankato Event Center
"It was kind of hard to find, but worth it."
Reviewed on Oct 9, 2026
The Berkman
"Room was awesome! We had the 3 bedroom unit, which had a large and spacious balcony. Plenty of sunlight came through those windows. We couldn’t had had a better room!"
Reviewed on Oct 9, 2026
Find cheap hotels in Southern Minnesota
You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Southern Minnesota hotel with Hotwire to complete your one-of-a-kind travel checklist.
For you, intrepid voyager, Hotwire has a large selection of the best hotels in Southern Minnesota.
Choosing the right hotel in Minnesota has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Southern Minnesota’s 1,234 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $84. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Southern Minnesota hotel deals at the last minute.
While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Southern Minnesota. No matter your reason for visiting Southern Minnesota, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.
Frequently Asked Questions About Southern Minnesota hotels
Where can I find the best last-minute travel deals?
If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Southern Minnesota for as low as $84.
How many hotels are there in Southern Minnesota?
With over 1,234 hotels in Southern Minnesota, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $84.
How to find cheap car rentals in Southern Minnesota?
Finding a cheap car rental deal in Southern Minnesota is as easy as scoring cheap hotels in Southern Minnesota. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.
- Hotel Brand
- Hotel Class
- Near An Airport
- Areas Of Southern Minnesota
- Near An Attraction
- Hotel Theme
- Other Cities Near Southern Minnesota
- Hotels near Mayo Clinic
- Hotels near Mayo Clinic Hospital - Saint Marys Campus
- Hotels near Treasure Island Casino
- Hotels near Mayo Civic Center
- Hotels near Mayo Clinic Health System Event Center
- Hotels near Minnesota State University
- Hotels near Jackpot Junction Casino
- Hotels near St. Olaf College
- Hotels near Lake Pepin
- Hotels near Apache Mall
- Hotels near Winona State University
- Hotels near Carleton College
- Hotels near Rochester Recreation Center
- Hotels near Rochester Community and Technical College
- Hotels near Laura Ingalls Wilder Museum
- Hotels near National Volleyball Center
- Hotels near University of Minnesota-Rochester
- Hotels near Welch Village Ski Area
- Hotels near Forestville Mystery Cave State Park
- Hotels near Mayo Clinic Health System Mankato
- Hotels with Free Parking in Southern Minnesota
- Family Hotels in Southern Minnesota
- Hotels with a Pool in Southern Minnesota
- Pet-friendly Hotels in Southern Minnesota
- Historic Hotels in Southern Minnesota
- Hotels with an Indoor Pool in Southern Minnesota
- Hotels with Hot Tubs in Southern Minnesota
- Resorts & Hotels with Spas in Southern Minnesota
- Luxury Hotels in Southern Minnesota
- Hotel Wedding Venues in Southern Minnesota
- Apartment Hotel in Southern Minnesota
- Winery Hotels in Southern Minnesota
- Romantic Hotels in Southern Minnesota
- Hotels with smoking rooms in Southern Minnesota
- Casinos in Southern Minnesota
- Hotels with Free Airport Shuttle in Southern Minnesota
- Hotels with Waterslides in Southern Minnesota
- Hotels with Early Check-in in Southern Minnesota
- Waterpark Hotels in Southern Minnesota
- Boutique Hotels in Southern Minnesota
- Sioux Falls Hotels
- Bloomington Hotels
- Rochester Hotels
- La Crosse Hotels
- St. Paul Hotels
- Stillwater Hotels
- Mankato Hotels
- Winona Hotels
- Eagan Hotels
- Shakopee Hotels
- Decorah Hotels
- Eden Prairie Hotels
- Red Wing Hotels
- Brookings Hotels
- Woodbury Hotels
- Hudson Hotels
- Okoboji Hotels
- Wabasha Hotels
- Lakeville Hotels
- Burnsville Hotels
