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Hotels in Southern Minnesota

Choose from 1196 Southern Minnesota Hotel Deals

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
  • 2 min walk from Mayo Clinic
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.4/10 Very Good! (2,132 reviews)
"1"

Reviewed on Jun 3, 2026

Kahler Grand Hotel
Treasure Island Resort & Casino

Treasure Island Resort & Casino

3 out of 5
5734 Sturgeon Lake Road Welch MN
  • 2 hours drive from Mayo Clinic
Book a stay at this spa hotel in Welch. Enjoy free WiFi, free parking, and a full-service spa. Popular attractions Treasure Island Casino and Island Xtreme Bowl ...
8.6/10 Excellent! (336 reviews)
"The room was nice but one really horrible thing was that the shower floor was extremely slippery. I didn't have too much trouble but if my husband had used it it could have been bad since he is currently using a cane for back trouble. The staff at the concert were awesome since there were no seats ..."

Reviewed on Jun 2, 2026

Treasure Island Resort & Casino
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
  • 3 min walk from Mayo Clinic
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (1,579 reviews)
"Front staff was very friendly and helpful - appreciated the early check-in. Staff we met in the hall were friendly and welcoming."

Reviewed on Jun 3, 2026

Kahler Inn and Suites - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3 out of 5
401 6th St Sw Rochester MN
  • 8 min walk from Mayo Clinic
Book a stay at this golf hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. ...
8.6/10 Excellent! (1,013 reviews)
"Came up for a Mayo visit. I selected this location because they advertised sound"

Reviewed on Jun 3, 2026

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
  • 7 min walk from Mayo Clinic
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,008 reviews)
"Found a bed bug"

Reviewed on Jun 3, 2026

Hyatt House Rochester/Mayo Clinic Area
Redwood Lodge

Redwood Lodge

2 out of 5
1382 E Bridge St Redwood Falls MN
  • 7 hours drive from Mayo Clinic
Stay at this hotel in Redwood Falls. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
9/10 Wonderful! (892 reviews)
"I liked staying at the Redwood Lodge. On my second overnight trip, I had to lodge elsewhere as the price was getting unaffordable for the working man. The breakfast buffet was outstanding. My biggest problem was I was assigned the only room in the building that did not have a number on the door. ..."

Reviewed on Jun 2, 2026

Redwood Lodge
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
  • 6 min walk from Mayo Clinic
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and ...
8.8/10 Excellent! (1,007 reviews)
"This is our go to place whenever we have appt at Mayo."

Reviewed on Jun 3, 2026

Hotel Indigo Rochester – Mayo Clinic Area by IHG
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw Rochester MN
  • 26 min walk from Mayo Clinic
Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,004 reviews)
"Cost-effective lodging. Room, facility, staff, & breakfast are adequate. I would go again if need an economical place to stay."

Reviewed on Jun 4, 2026

Med City Inn & Suites - Mayo Clinic Area
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4 out of 5
101 11TH Avenue SW Rochester MN
  • 17 min walk from Mayo Clinic
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9.4/10 Exceptional! (1,004 reviews)
"Extremely slow & impersonal front desk. Messed up our keys & had to spend 10 minutes getting it resolved. Very competent & kind breakfast server & decent breakfast options. Parking, shuttle & location all good."

Reviewed on Jun 2, 2026

EVEN Hotel Rochester - Mayo Clinic Area by IHG
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 out of 5
1517 16th St Sw Rochester MN
  • 5 min drive from Mayo Clinic
Book a stay at this family-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.2/10 Very Good! (931 reviews)
"The bathroom was not good. Specifically the toilet area and bathtub"

Reviewed on Jun 3, 2026

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3 out of 5
4353 Canal Pl SE Rochester MN
  • 11 min drive from Mayo Clinic
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.4/10 Good! (1,059 reviews)
"Really nice property. Front desk clerk Rao was very helpful when I checked in. Room was wonderful and roomy. Hot showers and comfy beds. Breakfast has nice variety of choices."

Reviewed on Jun 2, 2026

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Hampton Inn Rochester-South

Hampton Inn Rochester-South

2.5 out of 5
1755 S Broadway Rochester MN
  • 4 min drive from Mayo Clinic
Stay at this hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,001 reviews)
"Clean and convenient"

Reviewed on Jun 3, 2026

Hampton Inn Rochester-South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Southern Minnesota

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