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Hotels in Southern Minnesota

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Tonight May 3 - May 4Next weekend May 9 - May 11

Choose from 1144 Southern Minnesota Hotel Deals

Kahler Grand Hotel
Kahler Grand Hotel
3 out of 5
20 2nd Ave Sw, Rochester, MN
  • 2 min walk from Mayo Clinic
The price is $187 per night from May 8 to May 9
$187
includes taxes & fees
May 8 - May 9
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.2/10 Very Good! (1,348 reviews)
"I stayed at Kahler Grand Hotel because it is convenient for Mayo Clinic visits. The hotel is old but they have done many renovations. There are a lot of shops and restaurants within walking distance. The staff was helpful and responsive. The AC in my room was not working well even after the maintenance ..."

Reviewed on Apr 30, 2025

Kahler Grand Hotel
AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic
3 out of 5
1625 Broadway Ave S, Rochester, MN
  • 4 min drive from Mayo Clinic
The price is $88 per night from May 4 to May 5
$88
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful ...
8/10 Very Good! (830 reviews)
"Over the top"

Reviewed on Apr 29, 2025

AmericInn by Wyndham Rochester Near Mayo Clinic
Med City Inn & Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area
2.5 out of 5
435 16th Ave Nw, Rochester, MN
  • 26 min walk from Mayo Clinic
The price is $102 per night from May 5 to May 6
$102
includes taxes & fees
May 5 - May 6
Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,002 reviews)
"And they have a shuttle to the Mayo clinic every hour."

Reviewed on May 2, 2025

Med City Inn & Suites - Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
3 out of 5
110 Civic Center Drive NW, Rochester, MN
  • 7 min walk from Mayo Clinic
The price is $123 per night from May 23 to May 24
$123
includes taxes & fees
May 23 - May 24
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (877 reviews)
"All was great except the construction in the area!"

Reviewed on Apr 26, 2025

Hyatt House Rochester/Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 out of 5
220 S Broadway, Rochester, MN
  • 6 min walk from Mayo Clinic
The price is $135 per night from May 16 to May 17
$135
includes taxes & fees
May 16 - May 17
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and ...
8.8/10 Excellent! (743 reviews)
"Quiet and very modern clean rooms"

Reviewed on Apr 30, 2025

Hotel Indigo Rochester – Mayo Clinic Area by IHG
Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
3.5 out of 5
9 3rd Ave Nw, Rochester, MN
  • 3 min walk from Mayo Clinic
The price is $175 per night from May 4 to May 5
$175
includes taxes & fees
May 4 - May 5
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
7.6/10 Good! (1,347 reviews)
Nice place
"Very nice rooms"

Reviewed on May 1, 2025

Kahler Inn and Suites - Mayo Clinic Area
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
3 out of 5
1125 2nd St Sw, Rochester, MN
  • 19 min walk from Mayo Clinic
The price is $111 per night from May 23 to May 24
$111
includes taxes & fees
May 23 - May 24
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (776 reviews)
"Nice place, good cookies"

Reviewed on May 2, 2025

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3 out of 5
4353 Canal Pl SE, Rochester, MN
  • 11 min drive from Mayo Clinic
The price is $78 per night from May 5 to May 6
$78
includes taxes & fees
May 5 - May 6
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.2/10 Good! (1,002 reviews)
"All good except the TV. Every time you turn it on, you had to select input on the TV. Remote control didn't work."

Reviewed on Apr 28, 2025

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
TownePlace Suites by Marriott Rochester Mayo Clinic Area
TownePlace Suites by Marriott Rochester Mayo Clinic Area
3 out of 5
601 2ND STREET SW, Rochester, MN
  • 7 min walk from Mayo Clinic
The price is $125 per night from May 16 to May 17
$125
includes taxes & fees
May 16 - May 17
Stay at this 3-star hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful staff in our ...
9.6/10 Exceptional! (408 reviews)
"Always comfortable to stay here. Clean, quiet and convenient location."

Reviewed on Apr 25, 2025

TownePlace Suites by Marriott Rochester Mayo Clinic Area
The Berkman
The Berkman
3 out of 5
217 14th Ave SW, Rochester, MN
  • 24 min walk from Mayo Clinic
The price is $137 per night from May 16 to May 17
$137
includes taxes & fees
May 16 - May 17
Stay at this 3-star golf aparthotel in Rochester. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...
9.6/10 Exceptional! (287 reviews)
"Great staff at check in"

Reviewed on Apr 30, 2025

The Berkman
EVEN Hotel Rochester - Mayo Clinic Area by IHG
EVEN Hotel Rochester - Mayo Clinic Area by IHG
4 out of 5
101 11TH Avenue SW, Suite A, Rochester, MN
  • 17 min walk from Mayo Clinic
The price is $139 per night from May 25 to May 26
$139
includes taxes & fees
May 25 - May 26
Stay at this 4-star business-friendly hotel in Rochester. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
9.4/10 Exceptional! (818 reviews)
"Would stay again"

Reviewed on Apr 27, 2025

EVEN Hotel Rochester - Mayo Clinic Area by IHG
Hampton Inn Rochester-South
Hampton Inn Rochester-South
2.5 out of 5
1755 S Broadway, Rochester, MN
  • 4 min drive from Mayo Clinic
The price is $102 per night from May 30 to May 31
$102
includes taxes & fees
May 30 - May 31
Stay at this hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,001 reviews)
"Old but nice"

Reviewed on Apr 30, 2025

Hampton Inn Rochester-South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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