Search for Cheap Deals on
Hotels in Southern Minnesota

Check Last Minute Southern Minnesota Hotel Deals

Tonight Dec 29 - Dec 30Next weekend Jan 3 - Jan 5

Choose from 1093 Southern Minnesota Hotel Deals

Kahler Grand Hotel
Kahler Grand Hotel
3 out of 5
20 2nd Ave Sw, Rochester, MN
  • 2 min walk from Mayo Clinic
The price is $172 per night from Dec 30 to Dec 31
$172
includes taxes & fees
Dec 30 - Dec 31
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
8/10 Very Good! (1,238 reviews)
Perfect place
"Great place"

Reviewed on Dec 22, 2024

Kahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
3.5 out of 5
9 3rd Ave Nw, Rochester, MN
  • 3 min walk from Mayo Clinic
The price is $160 per night from Dec 30 to Dec 31
$160
includes taxes & fees
Dec 30 - Dec 31
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
7.6/10 Good! (1,284 reviews)
"The light switch by the door of the room did not turn any light on."

Reviewed on Dec 27, 2024

Kahler Inn and Suites - Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
3 out of 5
110 Civic Center Drive NW, Rochester, MN
  • 7 min walk from Mayo Clinic
The price is $128 per night from Jan 12 to Jan 13
$128
includes taxes & fees
Jan 12 - Jan 13, 2025
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (787 reviews)
"The property was very nice - comfy clean rooms. What set it apart for us was the staff. The check-in clerk/bartender Scott was very personable and multi-tasked all of the lobby demands very well. The breakfast staff was very outgoing and friendly, and service-oriented."

Reviewed on Dec 22, 2024

Hyatt House Rochester/Mayo Clinic Area
AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic
3 out of 5
1625 Broadway Ave S, Rochester, MN
  • 4 min drive from Mayo Clinic
The price is $85 per night from Jan 1 to Jan 2
$85
includes taxes & fees
Jan 1 - Jan 2, 2025
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful ...
8/10 Very Good! (653 reviews)
"Our stay at the Americinn in Rochester Mn. was very good. The Staff was very polite and very help full. I would highly recommend this hotel."

Reviewed on Dec 23, 2024

AmericInn by Wyndham Rochester Near Mayo Clinic
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
4 out of 5
101 11TH Avenue SW, Suite A, Rochester, MN
  • 17 min walk from Mayo Clinic
The price is $132 per night from Jan 24 to Jan 25
$132
includes taxes & fees
Jan 24 - Jan 25, 2025
Stay at this 4-star business-friendly hotel in Rochester. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
9.4/10 Exceptional! (766 reviews)
"WATCH OUT! Parking is an issue, and most you have to pay for. There are yoga mats in the room, which is odd. No Bible."

Reviewed on Dec 24, 2024

EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
3.5 out of 5
220 S Broadway, Rochester, MN
  • 6 min walk from Mayo Clinic
The price is $140 per night from Jan 10 to Jan 11
$140
includes taxes & fees
Jan 10 - Jan 11, 2025
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and ...
8.8/10 Excellent! (660 reviews)
"New clean rooms"

Reviewed on Dec 26, 2024

Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3 out of 5
401 6th St Sw, Rochester, MN
  • 8 min walk from Mayo Clinic
The price is $142 per night from Dec 30 to Dec 31
$142
includes taxes & fees
Dec 30 - Dec 31
Book a stay at this golf hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. ...
8.2/10 Very Good! (999 reviews)
Perfect spot for shuttles to Mayo
"Convenient for shuttling to Mayo. Great restaurant attached. Comfortable and quiet."

Reviewed on Dec 21, 2024

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Hampton Inn Rochester-South
Hampton Inn Rochester-South
2.5 out of 5
1755 S Broadway, Rochester, MN
  • 4 min drive from Mayo Clinic
The price is $96 per night from Jan 24 to Jan 25
$96
includes taxes & fees
Jan 24 - Jan 25, 2025
Stay at this hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,001 reviews)
A great stay
"The front desk clerk was friendly and welcoming while still being professional and he made check-in a great experience after a long day. Hotel is clean, our room was clean, and beds very comfortable. Great hospitality and making us feel like valued guests. Definitely will recommend and stay here ..."

Reviewed on Dec 25, 2024

Hampton Inn Rochester-South
Med City Inn & Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area
2.5 out of 5
435 16th Ave Nw, Rochester, MN
  • 26 min walk from Mayo Clinic
The price is $92 per night from Dec 30 to Dec 31
$92
includes taxes & fees
Dec 30 - Dec 31
Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,004 reviews)
Comfortable Stay
"Good hotel to stay at when visiting Mayo Clinic"

Reviewed on Dec 27, 2024

Med City Inn & Suites - Mayo Clinic Area
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3 out of 5
4353 Canal Pl SE, Rochester, MN
  • 11 min drive from Mayo Clinic
The price is $82 per night from Jan 5 to Jan 6
$82
includes taxes & fees
Jan 5 - Jan 6, 2025
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.4/10 Good! (1,000 reviews)
"It was so peaceful and the rooms were so nice. Perfect place to stay!! Actually I didn't want to leave."

Reviewed on Dec 21, 2024

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 out of 5
1517 16th St Sw, Rochester, MN
  • 5 min drive from Mayo Clinic
The price is $97 per night from Jan 5 to Jan 6
$97
includes taxes & fees
Jan 5 - Jan 6, 2025
Book a stay at this family-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.2/10 Very Good! (490 reviews)
"Friendlu staff, deliciois breakfast, clean. Safe. What else would you want!"

Reviewed on Dec 20, 2024

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
3 out of 5
1125 2nd St Sw, Rochester, MN
  • 19 min walk from Mayo Clinic
The price is $119 per night from Jan 1 to Jan 2
$119
includes taxes & fees
Jan 1 - Jan 2, 2025
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (692 reviews)
"Nice location for St. Mary’s at Mayo and shuttle service available. Hotel has had some upgrades over the years that I have noticed."

Reviewed on Dec 9, 2024

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Southern Minnesota

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Southern Minnesota hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Southern Minnesota.

Choosing the right hotel in Minnesota has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Southern Minnesota’s 1,093 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $82. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Southern Minnesota hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Southern Minnesota. No matter your reason for visiting Southern Minnesota, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Southern Minnesota hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Southern Minnesota for as low as $82.

How many hotels are there in Southern Minnesota?

With over 1,093 hotels in Southern Minnesota, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $82.

How to find cheap car rentals in Southern Minnesota?

Finding a cheap car rental deal in Southern Minnesota is as easy as scoring cheap hotels in Southern Minnesota. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.