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Featured Northwest Hotels

Kahler Grand Hotel
Kahler Grand Hotel
3 out of 5
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.2/10 Very Good! (1,338 reviews)
"Very courteous staff. Very helpful."

Reviewed on Apr 12, 2025

Kahler Grand Hotel
AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic
3 out of 5
1625 Broadway Ave S, Rochester, MN
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful ...
8/10 Very Good! (799 reviews)
"Moldy windows"

Reviewed on Apr 9, 2025

AmericInn by Wyndham Rochester Near Mayo Clinic
Med City Inn & Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area
2.5 out of 5
435 16th Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,001 reviews)
"Very nice place to stay! Good price, good breakfast options, convenient, pool, hot tub, nice staff & clean room."

Reviewed on Apr 8, 2025

Med City Inn & Suites - Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
3 out of 5
110 Civic Center Drive NW, Rochester, MN
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (867 reviews)
"Staff was friendly and helpful. There were two volleyball teams there when we stayed, yet the place was fairly quiet. Could use a little higher grade of tissue and toilet paper - it was pretty scratchy and rough."

Reviewed on Apr 6, 2025

Hyatt House Rochester/Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
3.5 out of 5
9 3rd Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
7.6/10 Good! (1,339 reviews)
"If have appointments at mayo clinic, it is very convenient. It’s a nice property. They are doing renovations. The restaurant on site doesn’t open till 3, would have been nice to have it as a lunch option"

Reviewed on Apr 7, 2025

Kahler Inn and Suites - Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 out of 5
220 S Broadway, Rochester, MN
Fully refundable
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and ...
8.8/10 Excellent! (729 reviews)
"Very comfortable. Nice room and on property restaurant was very good."

Reviewed on Apr 7, 2025

Hotel Indigo Rochester – Mayo Clinic Area by IHG
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3 out of 5
4353 Canal Pl SE, Rochester, MN
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.4/10 Good! (1,001 reviews)
"It was comfortable, good location for shopping."

Reviewed on Apr 8, 2025

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
EVEN Hotel Rochester - Mayo Clinic Area by IHG
EVEN Hotel Rochester - Mayo Clinic Area by IHG
4 out of 5
101 11TH Avenue SW, Suite A, Rochester, MN
Fully refundable
Stay at this 4-star business-friendly hotel in Rochester. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
9.4/10 Exceptional! (815 reviews)
Clean, comfortable, convenient.
"I am very particular about hotels/accommodations. I’ve stayed here many times and I will continue to do so. It is clean, comfortable, convenient, and everyone is helpful and friendly."

Reviewed on Apr 10, 2025

EVEN Hotel Rochester - Mayo Clinic Area by IHG
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 out of 5
1517 16th St Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
Book a stay at this family-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.2/10 Very Good! (585 reviews)
"Property was good, staff was friendly and helpful. The pool area was very busy and there were no towels available the entire time we were in the pool area (approximately an hour). I understand because of the size of the crowd but it was still a negative."

Reviewed on Apr 6, 2025

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Hampton Inn Rochester-South
Hampton Inn Rochester-South
2.5 out of 5
1755 S Broadway, Rochester, MN
Fully refundableReserve now, pay when you stay
Stay at this hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,006 reviews)
"I was there overnight for an appointment at the Mayo Clinc, I was able to check"

Reviewed on Apr 11, 2025

Hampton Inn Rochester-South
The Berkman
The Berkman
3 out of 5
217 14th Ave SW, Rochester, MN
Fully refundableReserve now, pay when you stay
Stay at this 3-star golf aparthotel in Rochester. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...
9.6/10 Exceptional! (282 reviews)
"Love the berkman. We stay here at the request of my son every time he has an appt at the mayo. He loves the golf simulator! It's a beautiful place. Highly recommended"

Reviewed on Apr 1, 2025

The Berkman
TownePlace Suites by Marriott Rochester Mayo Clinic Area
TownePlace Suites by Marriott Rochester Mayo Clinic Area
3 out of 5
601 2ND STREET SW, Rochester, MN
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful staff in our ...
9.6/10 Exceptional! (397 reviews)
"The room well equipped with the conveniences need for an extended stay. Unfortunately, there was only one slow elevator operating for my 4 day stay."

Reviewed on Apr 9, 2025

TownePlace Suites by Marriott Rochester Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Northwest

Rochester is a city that has a lot going on, but you have your sights set on Northwest. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Northwest has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Northwest hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Rochester so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Northwest underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Northwest city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Northwest cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Northwest at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $88
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Northwest hotel you want, book it, and never look back. Because your great escape is ahead of you.