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Featured Northwest Hotels

Kahler Grand Hotel
Kahler Grand Hotel
3 out of 5
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.2/10 Very Good! (1,363 reviews)
"Great hotel!"

Reviewed on May 21, 2025

Kahler Grand Hotel
AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic
3 out of 5
1625 Broadway Ave S, Rochester, MN
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful ...
8/10 Very Good! (859 reviews)
"All in all it’s a good place when staying for Mayo appts. Seems to be an older property though and in need of repairs - whoever cleans rooms doesn’t do a thorough job."

Reviewed on May 22, 2025

AmericInn by Wyndham Rochester Near Mayo Clinic
Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
3.5 out of 5
9 3rd Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
7.6/10 Good! (1,351 reviews)
"I’ve been staying here since March of 2009. This was one of my most unsatisfied stay!! We got to our room and went to use the bathroom and there was a long streak of bowls going down on the front of the stool!!! Then my husband went to the air on and the filters were on the floor and they were so ..."

Reviewed on May 18, 2025

Kahler Inn and Suites - Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
3 out of 5
110 Civic Center Drive NW, Rochester, MN
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (899 reviews)
"Bathroom outlet didn’t work. A lamp didn’t have a light bulb. Found dog food under a shelf."

Reviewed on May 20, 2025

Hyatt House Rochester/Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 out of 5
220 S Broadway, Rochester, MN
Fully refundable
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and ...
8.8/10 Excellent! (766 reviews)
"Beautiful property, CRAVE was great option for dinner on site. Parking structure under renovation currently. Close to Mayo Clinic and connected to Skyway."

Reviewed on May 19, 2025

Hotel Indigo Rochester – Mayo Clinic Area by IHG
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
3 out of 5
1125 2nd St Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (787 reviews)
"Wonderful staff!"

Reviewed on May 21, 2025

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
Med City Inn & Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area
2.5 out of 5
435 16th Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,001 reviews)
"Stayed there because the hotel was closest to the Mayo Clinic. I loved how spacious the rooms were and how accommodating the staff was when I told them I needed another night in this same room. They’re all polite and easy to talk too. Had no issues with the establishment. Breakfast was always so ..."

Reviewed on May 19, 2025

Med City Inn & Suites - Mayo Clinic Area
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3 out of 5
161 13th Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
9/10 Wonderful! (708 reviews)
"Really lovely space, except the hot tub was not terribly warm"

Reviewed on May 18, 2025

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3 out of 5
4353 Canal Pl SE, Rochester, MN
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.2/10 Good! (1,001 reviews)
"the pool and spa are well maintained and clean. Hours are very good for swimming. Breakfast buffet is plentiful and well maintained. The attendant at breakfast is attentive and helpful."

Reviewed on May 20, 2025

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
The Berkman
The Berkman
3 out of 5
217 14th Ave SW, Rochester, MN
Fully refundableReserve now, pay when you stay
Stay at this 3-star golf aparthotel in Rochester. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...
9.6/10 Exceptional! (293 reviews)
"We always have a very nice stay at the Berkman. It’s always clean and meets all of our needs. Great location if you have appointments at st. Mary’s."

Reviewed on May 18, 2025

The Berkman
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3 out of 5
401 6th St Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
Book a stay at this golf hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. ...
8.4/10 Very Good! (1,004 reviews)
"This was our second stay over the past year and we will be back in six months. The hotel is always clean, the linens are clean, but unscented detergent used… This is a real plus if you have allergies like I do! Friendly and responsive staff. Good breakfast. The shuttle service between the hotel and ..."

Reviewed on May 22, 2025

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
EVEN Hotel Rochester - Mayo Clinic Area by IHG
EVEN Hotel Rochester - Mayo Clinic Area by IHG
4 out of 5
101 11TH Avenue SW, Suite A, Rochester, MN
Fully refundable
Stay at this 4-star business-friendly hotel in Rochester. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
9.4/10 Exceptional! (826 reviews)
"A bit high on cost but great room and people."

Reviewed on May 22, 2025

EVEN Hotel Rochester - Mayo Clinic Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Northwest

Rochester is a city that has a lot going on, but you have your sights set on Northwest. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Northwest has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Northwest hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Rochester so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Northwest underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Northwest city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Northwest cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Northwest at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Northwest hotel you want, book it, and never look back. Because your great escape is ahead of you.