Search for Cheap Deals onHotels in Byron
Choose from 394 Byron Hotel Deals

Kahler Grand Hotel
Clean and close to the Mayo Clinic.
Reviewed on Apr 11, 2026

Kahler Inn and Suites - Mayo Clinic Area
It was a huge disappointment. We bought our own breakfast. The coffee was unsinkable and many others were complaining of same.
Reviewed on Apr 11, 2026

Hotel Indigo Rochester – Mayo Clinic Area by IHG
I had to travel to The Mayo Clinic in Rochester, MN, for a week.and was given the name of the hotel as one choice close to the clinics I had to visit by the concierge service. It is connected via indoor skyway to the main outpatient Mayo campus, including the Gonda building. The parking was very ...
Reviewed on Apr 9, 2026

EVEN Hotel Rochester - Mayo Clinic Area by IHG
Parking lot was full and had to park on street, did get a parking ticket.
Reviewed on Apr 11, 2026

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Breakfast was fine, didn’t use the pool facilities.
Reviewed on Apr 11, 2026

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Hot water was not available in bathroom. Rm 818.
Reviewed on Apr 11, 2026

Aspen Suites
This hotel had spacious clean rooms with kitchens and comfy beds. They offered complimentary breakfast, laundry, and light supper. That was a happy surprise. The shuttle to Mayo Clinic came by often. Underground parking was also free.
Reviewed on Apr 10, 2026

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
Well stocked breakfast bar.
Reviewed on Apr 10, 2026

Spark by Hilton Rochester South
Breakfast was interesting Little prepackaged everythings Nothing that looked appetizing Did not even dip my toe
Reviewed on Apr 10, 2026

AmericInn by Wyndham Rochester Near Mayo Clinic
Good breakfast, big hot tub, nice pool space
Reviewed on Apr 9, 2026

Brentwood Inn & Suites
Parking was good. The shuttle to Mayo was very helpful. With all the construction going on, it was great to be let off right at the door. The breakfast - I didn't really like having to take the cold food from the frig and heat it in the microwave. There were many trying to use at the same time. The ...
Reviewed on Apr 10, 2026

Hyatt House Rochester/Mayo Clinic Area
The hotel itself had all the amenities. The room tv stand that had the microwave and fridge the doors did not close properly. It was difficult to get to the fridge as the tv stand door kept closing in on it. The closet door had stains on it as well and the light pole had not been wiped down. The ...
Reviewed on Apr 8, 2026
Find cheap hotels in Byron
You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Byron hotel with Hotwire to complete your one-of-a-kind travel checklist.
For you, intrepid voyager, Hotwire has a large selection of the best hotels in Byron.
Choosing the right hotel in Minnesota has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Byron’s 394 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $80. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Byron hotel deals at the last minute.
While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Byron. No matter your reason for visiting Byron, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.
Frequently Asked Questions About Byron hotels
Where can I find the best last-minute travel deals?
If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Byron for as low as $80.
How many hotels are there in Byron?
With over 394 hotels in Byron, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $80.
How to find cheap car rentals in Byron?
Finding a cheap car rental deal in Byron is as easy as scoring cheap hotels in Byron. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.
- Rochester Hotels
- Owatonna Hotels
- Lake City Hotels
- Austin Hotels
- Southern Minnesota Hotels
- Zumbrota Hotels
- Stewartville Hotels
- Chatfield Hotels
- Kasson Hotels
- Spring Valley Hotels
- Oronoco Hotels
- Plainview Hotels
- Goodhue Hotels
- Central United States Hotels
- Kenyon Hotels
- Eyota Hotels
- Blooming Prairie Hotels
- Grand Meadow Hotels
- Mantorville Hotels
- Southeast Minnesota Hotels


