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Choose from 320 Wykoff Hotel Deals

Kahler Grand Hotel
Kahler Grand Hotel
3 out of 5
20 2nd Ave Sw, Rochester, MN
  • 1 hour drive from Ed's Museum
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.2/10 Very Good! (1,373 reviews)
"Very convenient location. Some things are dated but kept up well."

Reviewed on May 30, 2025

Kahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
3.5 out of 5
9 3rd Ave Nw, Rochester, MN
  • 1 hour drive from Ed's Museum
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
7.6/10 Good! (1,348 reviews)
"Convenient to MAYO Clinic"

Reviewed on May 28, 2025

Kahler Inn and Suites - Mayo Clinic Area
AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic
3 out of 5
1625 Broadway Ave S, Rochester, MN
  • 58 min drive from Ed's Museum
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful ...
8/10 Very Good! (873 reviews)
"Centrally located"

Reviewed on May 27, 2025

AmericInn by Wyndham Rochester Near Mayo Clinic
Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
3 out of 5
110 Civic Center Drive NW, Rochester, MN
  • 1 hour drive from Ed's Museum
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (904 reviews)
"all was fine"

Reviewed on May 28, 2025

Hyatt House Rochester/Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 out of 5
220 S Broadway, Rochester, MN
  • 1 hour drive from Ed's Museum
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and ...
8.8/10 Excellent! (771 reviews)
"Beautiful property, CRAVE was great option for dinner on site. Parking structure under renovation currently. Close to Mayo Clinic and connected to Skyway."

Reviewed on May 19, 2025

Hotel Indigo Rochester – Mayo Clinic Area by IHG
Med City Inn & Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area
2.5 out of 5
435 16th Ave Nw, Rochester, MN
  • 1 hour drive from Ed's Museum
Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,001 reviews)
"If you ever have to be an outpatient at the Mayo Clinic and need somewhere to stay while trying to conserve money and yet have a nice place. I highly recommend you stay here at the med city Inn and suites! Famous Dave’s is connected in the front and you get a discount to eat there and delivered to ..."

Reviewed on May 25, 2025

Med City Inn & Suites - Mayo Clinic Area
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
3 out of 5
1125 2nd St Sw, Rochester, MN
  • 1 hour drive from Ed's Museum
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (798 reviews)
"n/a"

Reviewed on May 28, 2025

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3 out of 5
4353 Canal Pl SE, Rochester, MN
  • 53 min drive from Ed's Museum
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.2/10 Good! (1,012 reviews)
"Everything was good for our stay,the only problem was the AC room was too hot !! But we enjoyed the pool definitely we staying there again when we came back to Minnesota!!"

Reviewed on May 27, 2025

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
EVEN Hotel Rochester - Mayo Clinic Area by IHG
EVEN Hotel Rochester - Mayo Clinic Area by IHG
4 out of 5
101 11TH Avenue SW, Suite A, Rochester, MN
  • 1 hour drive from Ed's Museum
Stay at this 4-star business-friendly hotel in Rochester. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
9.4/10 Exceptional! (828 reviews)
"It was a nice hotel but our sheets had a stain by the head of the bed."

Reviewed on May 28, 2025

EVEN Hotel Rochester - Mayo Clinic Area by IHG
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3 out of 5
401 6th St Sw, Rochester, MN
  • 1 hour drive from Ed's Museum
Book a stay at this golf hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. ...
8.4/10 Very Good! (1,000 reviews)
"Front desk staff were exceptionally friendly and helpful. OK, we stayed for six nights, since we had appointments at the Mayo Clinic - I feel like the hotel goes out of its way to feel like your “home away from home” while in Rochester. I’d definitely stay there again!"

Reviewed on May 26, 2025

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3 out of 5
161 13th Ave Sw, Rochester, MN
  • 1 hour drive from Ed's Museum
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
9/10 Wonderful! (711 reviews)
"Very clean and super nice at front desk"

Reviewed on May 24, 2025

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
The Berkman
The Berkman
3 out of 5
217 14th Ave SW, Rochester, MN
  • 1 hour drive from Ed's Museum
Stay at this 3-star golf aparthotel in Rochester. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...
9.6/10 Exceptional! (295 reviews)
"Great place in Rochester. Nicest hotel"

Reviewed on May 25, 2025

The Berkman
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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