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Choose from 316 Wykoff Hotel Deals

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
  • 1 hour drive from Ed's Museum
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.4/10 Very Good! (2,178 reviews)
"What an incredible hotel. From the Valet to the Front Desk, and the restaurants…. INCREDIBLE! The access to downtown and the underground mall are a great treat. Had no idea we could go down the elevator and right j in not Mayo Clinic without going outside! Big bonus!! Do it now! I will be…."

Reviewed on Jul 2, 2026

Kahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
  • 1 hour drive from Ed's Museum
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (1,604 reviews)
"Staff was very helpful and pleasant both at check in and check out. Breakfast was very good. Location was perfect, walking distance to many restaurants and civic center. Would definitely stay here again."

Reviewed on Jul 3, 2026

Kahler Inn and Suites - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3 out of 5
401 6th St Sw Rochester MN
  • 1 hour drive from Ed's Museum
Book a stay at this golf hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. ...
8.6/10 Excellent! (1,004 reviews)
"Room was dated and waste can had not been emptied. Front desk staff were not especially helpful."

Reviewed on Jul 2, 2026

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw Rochester MN
  • 1 hour drive from Ed's Museum
Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,004 reviews)
"The room was very clean. Excellent stay for the price."

Reviewed on Jun 30, 2026

Med City Inn & Suites - Mayo Clinic Area
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 out of 5
1517 16th St Sw Rochester MN
  • 1 hour drive from Ed's Museum
Book a stay at this family-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.2/10 Very Good! (967 reviews)
"Loved our stay here. The pool was a hit with the kids. The staff were amazing, helpful, and friendly. Slept great. Didn't love the lighting (cold white light) and obvious wear and tear in the room, but was clean and comfortable. Would stay again."

Reviewed on Jul 3, 2026

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3 out of 5
4353 Canal Pl SE Rochester MN
  • 53 min drive from Ed's Museum
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.4/10 Good! (1,067 reviews)
"My go to hotel in Rochester now. Always excellent in all areas"

Reviewed on Jul 1, 2026

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
  • 1 hour drive from Ed's Museum
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,000 reviews)
"The good: Clean room, comfortable bed, very kind staff, great breakfast, convenient parking garage. The bad: Wall outlets in the room were all very loose and nothing would stay plugged in (the weight of the plug would cause it to fall out). There were no bath towels in the room (I assume the cleaning ..."

Reviewed on Jul 1, 2026

Hyatt House Rochester/Mayo Clinic Area
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4 out of 5
101 11TH Avenue SW Rochester MN
  • 1 hour drive from Ed's Museum
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9.4/10 Exceptional! (1,000 reviews)
"Very friendly staff and conventily located!"

Reviewed on Jul 1, 2026

EVEN Hotel Rochester - Mayo Clinic Area by IHG
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S Rochester MN
  • 58 min drive from Ed's Museum
Book a stay at this spa hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful staff in our ...
8/10 Very Good! (1,372 reviews)
"Clean room and bathroom. Budget-friendly. Comfortable beds. The refrigerator was not cold. My 15 yo daughter and I only needed to stay for one night, so it was not a big deal. There was only one usable outlet near the bed, which prevented more than one person to plug anything in next to the bed. ..."

Reviewed on Jul 2, 2026

AmericInn by Wyndham Rochester Near Mayo Clinic
Hampton Inn Rochester-South

Hampton Inn Rochester-South

2.5 out of 5
1755 S Broadway Rochester MN
  • 58 min drive from Ed's Museum
Stay at this hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,003 reviews)
"The rooms were clean and comfortable. There were two kinds of excellent soups being served when we arrived at 6pm with bread and crackers... we've never seen a hotel do that before! The breakfast was great, too!"

Reviewed on Jul 2, 2026

Hampton Inn Rochester-South
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
  • 1 hour drive from Ed's Museum
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and ...
8.8/10 Excellent! (1,001 reviews)
"Everything"

Reviewed on Jul 2, 2026

Hotel Indigo Rochester – Mayo Clinic Area by IHG
The Berkman

The Berkman

3 out of 5
217 14th Ave SW Rochester MN
  • 1 hour drive from Ed's Museum
Book a stay at this golf aparthotel in Rochester. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...
9.6/10 Exceptional! (421 reviews)
"Wonderful property with a few caveats. The amenities are great, and the location is ideal for St Mary’s. The apartment is large and parking safe and easy. That said, the bed is very hard and pillows aren’t great. The vents also hit directly on your face in the bed, so that was hard to get used to. ..."

Reviewed on Jul 2, 2026

The Berkman
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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