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Choose from 335 Wykoff Hotel Deals
Kahler Grand Hotel
The property was beautiful. Very large. Many different shops and places to eat. Attached to part of Mayo Clinic.
Reviewed on Apr 30, 2026
Kahler Inn and Suites - Mayo Clinic Area
1
Reviewed on Apr 29, 2026
Med City Inn & Suites - Mayo Clinic Area
Pool is wonderful with play stuff for kids and a great hot tub. The breakfast area is the cleanest ever! There is no meat for breakfast but otherwise anything you'd need. Great job there! The property is attached to Famous Dave's BBQ and it is GREAT! The property is old but clean. If you had to, ...
Reviewed on Apr 27, 2026
AmericInn by Wyndham Rochester Near Mayo Clinic
Excellent
Reviewed on Apr 29, 2026
Hyatt House Rochester/Mayo Clinic Area
Excelente
Reviewed on Apr 29, 2026
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
I realized at some point in the evening the over night oximetry machine I had from the Mayo Clinic was missing. Assuming I forgot it on the hotel shuttle I went to the front desk in a panic. The lack of concern from the desk attendant was quite disappointing. Knowing she could have made a quick call ...
Reviewed on Apr 29, 2026
EVEN Hotel Rochester - Mayo Clinic Area by IHG
One of the best hotels I've ever stayed at. The staff were very friendly and helpful. The only downside would be the parking situation, which the staff was very helpful in explaining it. I also love how i cant hear people out in the hallway or next door. Lots of privacy and rest.
Reviewed on Apr 25, 2026
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Looks newly renovated, decorated and furnished. Contemporary decor and fixtures. Comfortable rooms..Cool indoor pool inside of an atrium... Convenient location for Mayo Clinic....Nearby restaurants. FREE PARKING.. Decent free breakfast. All in all great bang for your buck.. Would stay again for sure. ...
Reviewed on Apr 30, 2026
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Good stay
Reviewed on Apr 22, 2026
Hampton Inn Rochester-South
The breakfast at this hotel was so delicious with oatmeal, waffles, fresh bagels and a varoety of toppings. They also have eggs, sausage and potatoes. This is a beautiful location, quiet and SO CLEAN. The staff were always kind and helpful.
Reviewed on Apr 29, 2026
The Berkman
Really the best place I've stayed in Rochester and being across the street from St Mary's was very helpful in getting in and out of the hospital. The staff and accommodations were perfect.
Reviewed on Apr 27, 2026
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
Cookies in the afternoon are great. So is the fruited water.
Reviewed on Apr 24, 2026
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