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Choose from 330 Wykoff Hotel Deals

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
  • 1 hour drive from Ed's Museum
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.4/10 Very Good! (1,959 reviews)
Overall, I had a good experience. That being said, I stayed in two different rooms. The first room was in the newer part of the building and it was so cold. No heat came out of the vents. I was miserable. The second night I stayed in the older part, it was fantastic.

Reviewed on Mar 20, 2026

Kahler Grand Hotel
Aspen Suites

Aspen Suites

3 out of 5
1211 2nd Street Rochester MN
  • 1 hour drive from Ed's Museum
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (770 reviews)
Best place to stay close to St. Mary’s Hospital. Warm and comfortable.

Reviewed on Mar 18, 2026

Aspen Suites
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
  • 1 hour drive from Ed's Museum
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (1,539 reviews)
Rooms are a little dated

Reviewed on Mar 20, 2026

Kahler Inn and Suites - Mayo Clinic Area
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4 out of 5
101 11TH Avenue SW Rochester MN
  • 1 hour drive from Ed's Museum
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9.4/10 Exceptional! (1,002 reviews)
Hotel was clean staff bery friendly

Reviewed on Mar 20, 2026

EVEN Hotel Rochester - Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
  • 1 hour drive from Ed's Museum
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and ...
8.8/10 Excellent! (963 reviews)
Perfect downtown location walking distance (skyway) to civic center

Reviewed on Mar 20, 2026

Hotel Indigo Rochester – Mayo Clinic Area by IHG
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 out of 5
1517 16th St Sw Rochester MN
  • 1 hour drive from Ed's Museum
Book a stay at this family-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.4/10 Very Good! (858 reviews)
Room is very clean. Hallways needed to be vacuumed but could have been due to weather. Polite staff!

Reviewed on Mar 20, 2026

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

3 out of 5
1125 2nd St Sw Rochester MN
  • 1 hour drive from Ed's Museum
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff ...
8.6/10 Excellent! (976 reviews)
The stay was good continental breakfast was good but the staff was rude and very impersonalable. When i am traveling 8 hours from home to have surgery and see a specialist I certainly don't want to be staying at hotel where the employees are rude and disrespectful and make you feel like an ...

Reviewed on Mar 20, 2026

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S Rochester MN
  • 58 min drive from Ed's Museum
Book a stay at this spa hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful staff in our ...
8.2/10 Very Good! (1,231 reviews)
Very nice staff. Breakfast fresh and good

Reviewed on Mar 21, 2026

AmericInn by Wyndham Rochester Near Mayo Clinic
Spark by Hilton Rochester South

Spark by Hilton Rochester South

3 out of 5
4165 Maine Ave SE Rochester MN
  • 52 min drive from Ed's Museum
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Spark by Hilton Rochester South
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
  • 1 hour drive from Ed's Museum
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,000 reviews)
Perfect for visiting Mayo Clinic

Reviewed on Mar 18, 2026

Hyatt House Rochester/Mayo Clinic Area
Brentwood Inn & Suites

Brentwood Inn & Suites

2.5 out of 5
123 Fourth Ave. NW Rochester MN
  • 1 hour drive from Ed's Museum
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,003 reviews)
Nice place and can get to the clinic via subway. The place is very dated and could use some upgrades.

Reviewed on Mar 20, 2026

Brentwood Inn & Suites
Aspen Select

Aspen Select

3.5 out of 5
1215 2nd St SW Rochester MN
  • 1 hour drive from Ed's Museum
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (1,004 reviews)
Aspen Select is a solid choice near St Mary's hospital. The staff are kind and attentive and although the outside may not be as new as other options, the rooms are comfortable with pullouts and recliners and amenities.

Reviewed on Mar 20, 2026

Aspen Select
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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