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Hotels in St. Charles

Choose from 487 St. Charles Hotel Deals

White Valley Motel
White Valley Motel
2.5 out of 5
449 W. 6th Street, St. Charles, MN
  • 1 hour drive from Mayo Clinic
Stay at this motel in St. Charles. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Whitewater River is located nearby.
5.8/10 (110 reviews)
"Place is clean but old. Staff got great personality and nice"

Reviewed on Jun 22, 2025

White Valley Motel
Kahler Grand Hotel
Kahler Grand Hotel
3 out of 5
20 2nd Ave Sw, Rochester, MN
  • 2 min walk from Mayo Clinic
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.2/10 Very Good! (1,410 reviews)
"Unique pool on top floor. Nice clean rooms. Very helpful front desk as staff."

Reviewed on Jun 20, 2025

Kahler Grand Hotel
AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic
3 out of 5
1625 Broadway Ave S, Rochester, MN
  • 4 min drive from Mayo Clinic
Book a stay at this spa hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful staff in our ...
8/10 Very Good! (895 reviews)
"We've been staying at this hotel when we come to mayo clinic every couple of weeks, for over a year. The breakfast area and food options have gone downhill--not kept up well. Used to have more attention given it."

Reviewed on Jun 21, 2025

AmericInn by Wyndham Rochester Near Mayo Clinic
Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
3 out of 5
110 Civic Center Drive NW, Rochester, MN
  • 7 min walk from Mayo Clinic
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (938 reviews)
Mayo Stay
"We really enjoy staying at the Hyatt House when my husband has appointments at Mayo. Just the right walking distance, easy to park, good breakfast and friendly peeps!"

Reviewed on Jun 22, 2025

Hyatt House Rochester/Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
3.5 out of 5
9 3rd Ave Nw, Rochester, MN
  • 3 min walk from Mayo Clinic
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
7.8/10 Good! (1,364 reviews)
"Conveniently connected to Mayo Clinic, decent room but definitely outdated. The bed dust ruffle had stains, which made the bed feel dirty, no room service, shower nozzle was difficult to work, room smelled"

Reviewed on Jun 20, 2025

Kahler Inn and Suites - Mayo Clinic Area
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3 out of 5
4353 Canal Pl SE, Rochester, MN
  • 11 min drive from Mayo Clinic
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.2/10 Good! (1,004 reviews)
"Good"

Reviewed on Jun 21, 2025

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
EVEN Hotel Rochester - Mayo Clinic Area by IHG
EVEN Hotel Rochester - Mayo Clinic Area by IHG
4 out of 5
101 11TH Avenue SW, Suite A, Rochester, MN
  • 17 min walk from Mayo Clinic
Stay at this 4-star business-friendly hotel in Rochester. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
9.4/10 Exceptional! (840 reviews)
"The property was clean and neat! It was an excellent stay!"

Reviewed on Jun 20, 2025

EVEN Hotel Rochester - Mayo Clinic Area by IHG
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3 out of 5
401 6th St Sw, Rochester, MN
  • 8 min walk from Mayo Clinic
Stay at this 3-star golf hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. ...
8.4/10 Very Good! (1,004 reviews)
"There are several buildings. It was difficult to know which one was ours."

Reviewed on Jun 22, 2025

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Country Inn & Suites Rochester South Mayo Clinic
Country Inn & Suites Rochester South Mayo Clinic
3 out of 5
77 Woodlake Drive SE, Rochester, MN
  • 8 min drive from Mayo Clinic
Stay at this 3-star family-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (1,001 reviews)
"Donna at the front desk was very polite and accommodating. My first room was facing the street and I asked for a different room and the 2nd room was perfect. She knew the area very well and suggested somewhere to eat that was very close . The hotel also provides a free shuttle to the Mayo ..."

Reviewed on Jun 16, 2025

Country Inn & Suites Rochester South Mayo Clinic
Express Suites Riverport Inn & Suites
Express Suites Riverport Inn & Suites
3 out of 5
900 Bruski Dr, Winona, MN
  • 2 hours drive from Mayo Clinic
Stay at this 3-star business-friendly hotel in Winona. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,002 reviews)
"The front desk person was very nice and helpful. She made everything very easy and quick which was good because we were tired from traveling all day."

Reviewed on Jun 16, 2025

Express Suites Riverport Inn & Suites
Aspen Select
Aspen Select
3.5 out of 5
1215 2nd St SW, Rochester, MN
  • 21 min walk from Mayo Clinic
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (1,002 reviews)
"Staff is excellent, location is convenient, rooms are comfortable and clean."

Reviewed on Jun 18, 2025

Aspen Select
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 out of 5
220 S Broadway, Rochester, MN
  • 6 min walk from Mayo Clinic
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and ...
8.8/10 Excellent! (780 reviews)
"Always a great choice!"

Reviewed on Jun 16, 2025

Hotel Indigo Rochester – Mayo Clinic Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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