Search for Cheap Deals onHotels in St. Charles
Choose from 502 St. Charles Hotel Deals
White Valley Motel
Very nice owner i wil come back again thank you..
Reviewed on Nov 14, 2025
Kahler Grand Hotel
There was not a free breakfast, so be prepared. Otherwise a very clean property. The staff were very courteous and approachable!
Reviewed on Jan 9, 2026
Kahler Inn and Suites - Mayo Clinic Area
We enjoy staying at Kahler Inn & Suites. So nice to be so close to Mayo Clinic. You don't have to go outside. You can walk from the hotel tp Mayo. Everyone is so friendly and the breakfast is great!
Reviewed on Jan 9, 2026
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Great stay, convenient and Crave being attached was an added bonus.
Reviewed on Jan 9, 2026
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Great clean and friendly hotel. Rooms were spacious and had a notably nice smell when you first walk in.
Reviewed on Jan 1, 2026
Aspen Suites
Multiple Mayo appts. Only issue entirely not to do with hotel- shuttle service was nice but several times the bus had 3x the allowed passenger limit. 65 counted on a 20 something passenger bus. Could have gotten off and waited an hour for last bus but heard it at 71 on it the day before!
Reviewed on Jan 8, 2026
Hyatt House Rochester/Mayo Clinic Area
Fast and easy
Reviewed on Jan 9, 2026
AmericInn by Wyndham Rochester Near Mayo Clinic
Room was nice. Good service. Unfortunately the lock on our room wouldn't work... Even after maintenance changed the battery and we tried seven different key cards. Luckily we weren't going anywhere after we got in.
Reviewed on Jan 9, 2026
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Friendly staff and very clean
Reviewed on Jan 1, 2026
Hampton Inn Rochester-South
Excellent
Reviewed on Jan 7, 2026
Spark by Hilton Rochester South
Manager was very nice. All the staff were great. Nice hotel.
Reviewed on Jan 8, 2026
Holiday Inn Express Rochester South - Mayo Area by IHG
Room very clean. Lady at front desk not very friendly and breakfast was cold
Reviewed on Jan 8, 2026
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