Search for Cheap Deals onHotels in St. Charles
Choose from 505 St. Charles Hotel Deals
Kahler Grand Hotel
No breakfast Parking in structure attached to hotel
Reviewed on Mar 27, 2026
Kahler Inn and Suites - Mayo Clinic Area
Breakfast was great. Staff awesome. Room clean. Parking challenging
Reviewed on Mar 27, 2026
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Aspen Suites
The staff is incredibly friendly and accommodating. A free shuttle to Mayo Clinic stops right outside the front lobby doors, Mayo St. Mary's Hospital is just across the street, and there are several restaurant options in walking distance from the property. The kitchenette in the suite, complementary ...
Reviewed on Mar 26, 2026
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Very clean. Ɓed was way too soft. The dining menu was limited but good. Had 3 meals there and were very satisfied. Servers were all incredible.
Reviewed on Mar 25, 2026
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
This was your second time staying here. Our first time we were in a pool side room and it was fine. Our second time thr tub wouldn’t drain. I went to the front desk. The front desk employee was so rude about it. The hot tub wasn’t “hot” and they do not enforce the 15 people in the hot tub rule even ...
Reviewed on Mar 27, 2026
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
Great
Reviewed on Mar 27, 2026
Spark by Hilton Rochester South
Clean room soft bed and pillows
Reviewed on Mar 23, 2026
Aspen Select
Aspen Select is a solid choice near St Mary's hospital. The staff are kind and attentive and although the outside may not be as new as other options, the rooms are comfortable with pullouts and recliners and amenities.
Reviewed on Mar 20, 2026
Brentwood Inn & Suites
Stayed for 4 nights while husband completed appointments at the Mayo Clinic. We didn't eat the breakfast, so not sure how that is. The rooms are good and the underground access to the Mayo Clinic is priceless.
Reviewed on Mar 27, 2026
Hyatt House Rochester/Mayo Clinic Area
The breakfast was good. The front desk receptionist was very rude.
Reviewed on Mar 27, 2026
AmericInn by Wyndham Rochester Near Mayo Clinic
The staff was friendly, the room was clean and updated. The attached restaurant was convenient and had great food and staff. Would stay here again.
Reviewed on Mar 27, 2026
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