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Hotels in St. Charles

Choose from 501 St. Charles Hotel Deals

Kahler Grand Hotel
Kahler Grand Hotel
3 out of 5
20 2nd Ave Sw, Rochester, MN
  • 2 min walk from Mayo Clinic
The price is $187 per night from Mar 5 to Mar 6
$187
includes taxes & fees
Mar 5 - Mar 6
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.2/10 Very Good! (1,306 reviews)
"I always stay at the Kahler when I have appointments at Mayo. It’s so convenient to get around, it’s clean and quiet."

Reviewed on Mar 3, 2025

Kahler Grand Hotel
Med City Inn & Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area
2.5 out of 5
435 16th Ave Nw, Rochester, MN
  • 26 min walk from Mayo Clinic
The price is $92 per night from Mar 5 to Mar 6
$92
includes taxes & fees
Mar 5 - Mar 6
Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,004 reviews)
"Great value for the price. Very good breakfast, comfortable bed, easy to get to and close enough to civic center and St Mary's hospital. The hot tub & pool were great"

Reviewed on Mar 2, 2025

Med City Inn & Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
3.5 out of 5
9 3rd Ave Nw, Rochester, MN
  • 3 min walk from Mayo Clinic
The price is $169 per night from Mar 5 to Mar 6
$169
includes taxes & fees
Mar 5 - Mar 6
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
7.6/10 Good! (1,315 reviews)
"Close to Mayo"

Reviewed on Feb 28, 2025

Kahler Inn and Suites - Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
3 out of 5
110 Civic Center Drive NW, Rochester, MN
  • 7 min walk from Mayo Clinic
The price is $132 per night from Mar 21 to Mar 22
$132
includes taxes & fees
Mar 21 - Mar 22
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (833 reviews)
"hotel is nice, pretty clean ,we could leave car during apt in Mayo and pic later"

Reviewed on Feb 27, 2025

Hyatt House Rochester/Mayo Clinic Area
AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic
3 out of 5
1625 Broadway Ave S, Rochester, MN
  • 4 min drive from Mayo Clinic
The price is $88 per night from Mar 16 to Mar 17
$88
includes taxes & fees
Mar 16 - Mar 17
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful ...
7.8/10 Good! (737 reviews)
"had everything we needed"

Reviewed on Mar 1, 2025

AmericInn by Wyndham Rochester Near Mayo Clinic
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
3.5 out of 5
220 S Broadway, Rochester, MN
  • 6 min walk from Mayo Clinic
The price is $137 per night from Apr 4 to Apr 5
$137
includes taxes & fees
Apr 4 - Apr 5
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and ...
8.8/10 Excellent! (700 reviews)
"Rooms are clean and neat."

Reviewed on Feb 26, 2025

Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 out of 5
1517 16th St Sw, Rochester, MN
  • 5 min drive from Mayo Clinic
The price is $108 per night from Mar 16 to Mar 17
$108
includes taxes & fees
Mar 16 - Mar 17
Book a stay at this family-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.2/10 Very Good! (564 reviews)
"Nice, clean property. Only issue is bugs, but that is explainable with the warm weather."

Reviewed on Feb 25, 2025

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3 out of 5
401 6th St Sw, Rochester, MN
  • 8 min walk from Mayo Clinic
The price is $142 per night from Mar 5 to Mar 6
$142
includes taxes & fees
Mar 5 - Mar 6
Book a stay at this golf hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. ...
8.2/10 Very Good! (1,003 reviews)
"Always friendly staff and quite place to stsy"

Reviewed on Feb 25, 2025

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
3 out of 5
1125 2nd St Sw, Rochester, MN
  • 19 min walk from Mayo Clinic
The price is $111 per night from Mar 21 to Mar 22
$111
includes taxes & fees
Mar 21 - Mar 22
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (732 reviews)
"Great"

Reviewed on Mar 2, 2025

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
Aspen Select
Aspen Select
3.5 out of 5
1215 2nd St SW, Rochester, MN
  • 21 min walk from Mayo Clinic
The price is $147 per night from Mar 6 to Mar 7
$147
includes taxes & fees
Mar 6 - Mar 7
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (1,003 reviews)
"Desk clerk at check in was very personable and helpful."

Reviewed on Feb 28, 2025

Aspen Select
Staybridge Suites Rochester - Mayo Clinic Area, an IHG Hotel
Staybridge Suites Rochester - Mayo Clinic Area, an IHG Hotel
3 out of 5
101 11th Ave SW, Rochester, MN
  • 17 min walk from Mayo Clinic
The price is $141 per night from Mar 22 to Mar 23
$141
includes taxes & fees
Mar 22 - Mar 23
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (321 reviews)
"Very kind staff as most guests are patients snd families at Mayo Clinic."

Reviewed on Feb 28, 2025

Staybridge Suites Rochester - Mayo Clinic Area, an IHG Hotel
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
4 out of 5
101 11TH Avenue SW, Suite A, Rochester, MN
  • 17 min walk from Mayo Clinic
The price is $147 per night from Mar 30 to Mar 31
$147
includes taxes & fees
Mar 30 - Mar 31
Stay at this 4-star business-friendly hotel in Rochester. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
9.4/10 Exceptional! (792 reviews)
Great!
"We stayed for a basketball tournament. There were tonssss of kids and they handled the chaos so well. Overall, the staff was great and happy to help as needed! Very clean and modern hotel rooms."

Reviewed on Feb 24, 2025

EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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