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Hotels in Southeast Minnesota

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Tonight Mar 15 - Mar 16Next weekend Mar 21 - Mar 23

Choose from 924 Southeast Minnesota Hotel Deals

Kahler Grand Hotel
Kahler Grand Hotel
3 out of 5
20 2nd Ave Sw, Rochester, MN
  • 2 min walk from Mayo Clinic
The price is $187 per night from Mar 16 to Mar 17
$187
includes taxes & fees
Mar 16 - Mar 17
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.2/10 Very Good! (1,310 reviews)
"Great"

Reviewed on Mar 13, 2025

Kahler Grand Hotel
AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic
3 out of 5
1625 Broadway Ave S, Rochester, MN
  • 4 min drive from Mayo Clinic
The price is $88 per night from Mar 19 to Mar 20
$88
includes taxes & fees
Mar 19 - Mar 20
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful ...
7.8/10 Good! (754 reviews)
Pretty Amazing
"This hotel was pretty amazing. We loved the pool and hot tub. Service was good. It was clean. The bed was extra comfortable and I got extra pillows like I requested.We would definitely stay here again."

Reviewed on Mar 13, 2025

AmericInn by Wyndham Rochester Near Mayo Clinic
Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
3 out of 5
110 Civic Center Drive NW, Rochester, MN
  • 7 min walk from Mayo Clinic
The price is $124 per night from Mar 22 to Mar 23
$124
includes taxes & fees
Mar 22 - Mar 23
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (842 reviews)
"Easy access to everything i needed"

Reviewed on Mar 12, 2025

Hyatt House Rochester/Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
3.5 out of 5
9 3rd Ave Nw, Rochester, MN
  • 3 min walk from Mayo Clinic
The price is $169 per night from Mar 16 to Mar 17
$169
includes taxes & fees
Mar 16 - Mar 17
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
7.6/10 Good! (1,323 reviews)
"Fan in bathroom is to loud"

Reviewed on Mar 13, 2025

Kahler Inn and Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area
2.5 out of 5
435 16th Ave Nw, Rochester, MN
  • 26 min walk from Mayo Clinic
The price is $92 per night from Mar 16 to Mar 17
$92
includes taxes & fees
Mar 16 - Mar 17
Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,004 reviews)
"Wonderful breakfast. Spacious room. Clean and friendly."

Reviewed on Mar 9, 2025

Med City Inn & Suites - Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 out of 5
220 S Broadway, Rochester, MN
  • 6 min walk from Mayo Clinic
The price is $135 per night from Apr 11 to Apr 12
$135
includes taxes & fees
Apr 11 - Apr 12
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and ...
8.8/10 Excellent! (705 reviews)
"Excellent for my second stay going through treatment at the Mayo Clinic."

Reviewed on Mar 9, 2025

Hotel Indigo Rochester – Mayo Clinic Area by IHG
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3 out of 5
401 6th St Sw, Rochester, MN
  • 8 min walk from Mayo Clinic
The price is $142 per night from Mar 16 to Mar 17
$142
includes taxes & fees
Mar 16 - Mar 17
Book a stay at this golf hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. ...
8.2/10 Very Good! (1,001 reviews)
"Nice hotel, helpful staff and excellent shuttle service to Mayo locations."

Reviewed on Mar 12, 2025

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
3 out of 5
1125 2nd St Sw, Rochester, MN
  • 19 min walk from Mayo Clinic
The price is $111 per night from Mar 22 to Mar 23
$111
includes taxes & fees
Mar 22 - Mar 23
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (740 reviews)
"Very nice property. Clean. Friendly staff."

Reviewed on Mar 14, 2025

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
EVEN Hotel Rochester - Mayo Clinic Area by IHG
EVEN Hotel Rochester - Mayo Clinic Area by IHG
4 out of 5
101 11TH Avenue SW, Suite A, Rochester, MN
  • 17 min walk from Mayo Clinic
The price is $129 per night from Mar 22 to Mar 23
$129
includes taxes & fees
Mar 22 - Mar 23
Stay at this 4-star business-friendly hotel in Rochester. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
9.4/10 Exceptional! (798 reviews)
"I liked the fitness aspect in each room (no I did not use it, but it was a nice to have). The rooms were clean, comfortable and very modern. Staff were fantastic and very helpful. Food tasted great and came out so quickly. Fantastic stay."

Reviewed on Mar 7, 2025

EVEN Hotel Rochester - Mayo Clinic Area by IHG
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 out of 5
1517 16th St Sw, Rochester, MN
  • 5 min drive from Mayo Clinic
The price is $108 per night from Mar 20 to Mar 21
$108
includes taxes & fees
Mar 20 - Mar 21
Book a stay at this family-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.2/10 Very Good! (573 reviews)
"The hotel was a bit on the noisy side, but the complimentary breakfast was incredible!"

Reviewed on Mar 13, 2025

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Holiday Inn Express Rochester South - Mayo Area by IHG
Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 out of 5
4141 Maine Avenue SE, Rochester, MN
  • 10 min drive from Mayo Clinic
The price is $97 per night from Mar 23 to Mar 24
$97
includes taxes & fees
Mar 23 - Mar 24
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,001 reviews)
"Very quiet, clean, great staff and easy parking"

Reviewed on Mar 7, 2025

Holiday Inn Express Rochester South - Mayo Area by IHG
Staybridge Suites Rochester - Mayo Clinic Area by IHG
Staybridge Suites Rochester - Mayo Clinic Area by IHG
3 out of 5
101 11th Ave SW, Rochester, MN
  • 17 min walk from Mayo Clinic
The price is $148 per night from Mar 22 to Mar 23
$148
includes taxes & fees
Mar 22 - Mar 23
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (331 reviews)
"We will definitely stay again, friendly staff, clean rooms, free shuttle to Mayo Clinic."

Reviewed on Mar 13, 2025

Staybridge Suites Rochester - Mayo Clinic Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Southeast Minnesota

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Frequently Asked Questions About Southeast Minnesota hotels

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