Search Deals on
Byron Vacation Packages

Build your package with 2 more options

Byron Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.
Super 8 by Wyndham Rochester Mayo Clinic Area

Super 8 by Wyndham Rochester Mayo Clinic Area

2 out of 5
Price was $443, price is now $401 per person
$401
per person
Sep 6 - Sep 10
found 1 day ago
Roundtrip non-stop flight included
Milwaukee (MKE) to Rochester (RST)
Stay at this hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mayo Civic Center and Olmsted County Fairgrounds are located nearby.
When I arrived to my room, it was about 90° in there, and I went to turn the AC unit on and the light was on to change filter.As the plastic cover was broke, I removed the filter and cleaned it.Reinstalled it. I let the lady at the front desk know about it.And I told her I took kleenex and folded it up in wedged it in the cover to hold it in place

Reviewed on Aug 5, 2026

Aspen Select

Aspen Select

3.5 out of 5
Price was $594, price is now $474 per person
$474
per person
Sep 6 - Sep 10
found 1 day ago
Roundtrip non-stop flight included
Milwaukee (MKE) to Rochester (RST)
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Mayo Civic Center and Apache Mall are located nearby.
The staff help was amazing...from the moment we checked in to the moment we left. Along with I had forgot my apple watch charger in the room and I was already about 45 mins out of Rochester and the hotel called me to let me know that I had left it and stated they could mail it to me. Monday night the front desk person made cookies for the desk. I had an issue with the A/C in the room and with out hestitation, the staff person moved usto another room. All and all a great experience. And they had free parking...huge bonus!!

Reviewed on Aug 5, 2026

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

3 out of 5
Price was $972, price is now $861 per person
$861
per person
Oct 19 - Oct 23
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Rochester (RST)
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff in our reviews. Popular attractions Mayo Civic Center and Kutzky Park Tennis Center are located nearby.

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
Price was $508, price is now $450 per person
$450
per person
Sep 6 - Sep 10
found 1 day ago
Roundtrip non-stop flight included
Milwaukee (MKE) to Rochester (RST)
Book a stay at this spa hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful staff in our reviews. Popular attractions Mayo Civic Center and Olmsted County Fairgrounds are located nearby.

The Towers At Kahler Grand Hotel

The Towers At Kahler Grand Hotel

4 out of 5
Price was $1,362, price is now $1,214 per person
$1,214
per person
Sep 6 - Sep 10
found 1 day ago
Roundtrip non-stop flight included
Milwaukee (MKE) to Rochester (RST)
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the helpful staff in our reviews. Popular attractions Mayo Civic Center and Plummer Building are located nearby.
Everyone was very helpful throughout our stay. Our Tower Suite was wonderful and amenities were great.

Reviewed on Jun 29, 2026

Baymont by Wyndham Rochester Mayo Clinic Area

Baymont by Wyndham Rochester Mayo Clinic Area

2.5 out of 5
Price was $454, price is now $409 per person
$409
per person
Sep 6 - Sep 10
found 1 day ago
Roundtrip non-stop flight included
Milwaukee (MKE) to Rochester (RST)
Stay at this motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mayo Civic Center and Olmsted County Fairgrounds are located nearby.
Location

Reviewed on Aug 5, 2026

Aspen Suites

Aspen Suites

3 out of 5
Price was $642, price is now $587 per person
$587
per person
Sep 6 - Sep 10
found 1 day ago
Roundtrip non-stop flight included
Milwaukee (MKE) to Rochester (RST)
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Mayo Civic Center and Kutzky Park Tennis Center are located nearby.
The hotel is a standard hotel. I did enjoy having a full fridge and a little kitchen. If staying for awhile in Rodchester. I would feel comfortable staying at the Aspen.

Reviewed on Aug 5, 2026

The Berkman

The Berkman

3 out of 5
Price was $1,043, price is now $954 per person
$954
per person
Oct 19 - Oct 23
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Rochester (RST)
Book a stay at this golf aparthotel in Rochester. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular attractions Mayo Civic Center and Kutzky Park Tennis Center are located nearby.
Good stuff

Reviewed on Aug 2, 2026

Byron Vacation Packages 3-4 Night Stays

Price found within the past 48 hours. Click for updated prices.
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
Price was $508, price is now $450 per person
$450
per person
Sep 6 - Sep 10
found 1 day ago
Roundtrip non-stop flight included
Milwaukee (MKE) to Rochester (RST)
Aspen Select

Aspen Select

3.5 out of 5
Kutzky Park
Price was $594, price is now $474 per person
$474
per person
Sep 6 - Sep 10
found 1 day ago
Roundtrip non-stop flight included
Milwaukee (MKE) to Rochester (RST)
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

3 out of 5
Kutzky Park
Price was $972, price is now $861 per person
$861
per person
Oct 19 - Oct 23
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Rochester (RST)
The Towers At Kahler Grand Hotel

The Towers At Kahler Grand Hotel

4 out of 5
Downtown Rochester
Price was $1,362, price is now $1,214 per person
$1,214
per person
Sep 6 - Sep 10
found 1 day ago
Roundtrip non-stop flight included
Milwaukee (MKE) to Rochester (RST)

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Tue, Oct 6 - Sun, Oct 11
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$189 Roundtrip, found 4 days ago
$189
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Oct 6 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Sun, Oct 11, priced at $189 found 4 days ago
Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$259 Roundtrip, found 4 days ago
$259
Roundtrip
found 4 days ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $259 found 4 days ago
Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$269 Roundtrip, found 4 days ago
$269
Roundtrip
found 4 days ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $269 found 4 days ago
American Airlines
Wed, Sep 9 - Fri, Sep 11
EWR
Newark Liberty Intl. Airport
RST
Rochester Intl.
$280 Roundtrip, found 5 days ago
$280
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Sep 9 from Newark Liberty Intl. Airport to Rochester Intl., returning Fri, Sep 11, priced at $280 found 5 days ago