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Byron Vacation Packages

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Byron Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3 out of 5
Price was $491, price is now $459 per person
$459
per person
Jan 18 - Jan 21
found 23 hours ago
Roundtrip flight included
Los Angeles (LAX) to Rochester (RST)
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. Popular attractions Mayo Civic Center and Marcus Rochester Cinema are located nearby.
Nice place!

Reviewed on Nov 10, 2026

The Berkman

The Berkman

3 out of 5
Price was $614, price is now $564 per person
$564
per person
Dec 18 - Dec 20
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Rochester (RST)
Book a stay at this golf aparthotel in Rochester. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular attractions Mayo Civic Center and Kutzky Park Tennis Center are located nearby.

Alexander Mansion Bed and Breakfast

Alexander Mansion Bed and Breakfast

3.5 out of 5
Price was $934, price is now $866 per person
$866
per person
Dec 14 - Dec 18
found 1 day ago
Roundtrip non-stop flight included
New York (LGA) to Rochester (RST)
Stay at this B&B in Winona. Enjoy free parking, a business center, and daily housekeeping. Popular attractions Winona Arts Center and Watkins Heritage Museum are located nearby.
Wonderful host Richard and the beautiful home

Reviewed on Nov 2, 2026

Extended Stay America Suites Rochester North

Extended Stay America Suites Rochester North

2.5 out of 5
Price was $511, price is now $474 per person
$474
per person
Jan 18 - Jan 21
found 23 hours ago
Roundtrip flight included
Los Angeles (LAX) to Rochester (RST)
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Mayo Civic Center and Douglas State Trail Head Rochester are located nearby.

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

3 out of 5
Price was $523, price is now $490 per person
$490
per person
Dec 18 - Dec 20
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Rochester (RST)
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff in our reviews. Popular attractions Mayo Civic Center and Kutzky Park Tennis Center are located nearby.
Clean, spacious and very modern. Would definitely stay here again.

Reviewed on Nov 6, 2026

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
Price was $536, price is now $504 per person
$504
per person
Dec 18 - Dec 20
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Rochester (RST)
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Mayo Civic Center and Shops University Square are located nearby.
Clean and nice hotel. Excellent breakfast.

Reviewed on Nov 13, 2026

Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
Price was $541, price is now $510 per person
$510
per person
Dec 18 - Dec 20
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Rochester (RST)
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mayo Civic Center and Plummer Building are located nearby.
Very convenient to Mayo Clinic using subway access from hotel. No need to walk outside.

Reviewed on Nov 13, 2026

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3 out of 5
Price was $519, price is now $489 per person
$489
per person
Dec 18 - Dec 20
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Rochester (RST)
Book a stay at this golf hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. Popular attractions Mayo Civic Center and Soldiers Field Veterans Memorial are located nearby.
I love the swimming pool

Reviewed on Nov 13, 2026

Byron Vacation Packages 3-4 Night Stays

Price found within the past 48 hours. Click for updated prices.
Extended Stay America Suites Rochester North

Extended Stay America Suites Rochester North

2.5 out of 5
Price was $511, price is now $474 per person
$474
per person
Jan 18 - Jan 21
found 23 hours ago
Roundtrip flight included
Los Angeles (LAX) to Rochester (RST)
Aspen Select

Aspen Select

3.5 out of 5
Kutzky Park
Price was $1,016, price is now $886 per person
$886
per person
Dec 14 - Dec 18
found 1 day ago
Roundtrip non-stop flight included
New York (LGA) to Rochester (RST)
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

3 out of 5
Kutzky Park
Price was $1,033, price is now $953 per person
$953
per person
Dec 14 - Dec 18
found 1 day ago
Roundtrip non-stop flight included
New York (LGA) to Rochester (RST)
Alexander Mansion Bed and Breakfast

Alexander Mansion Bed and Breakfast

3.5 out of 5
Historic Downtown Winona
Price was $934, price is now $866 per person
$866
per person
Dec 14 - Dec 18
found 1 day ago
Roundtrip non-stop flight included
New York (LGA) to Rochester (RST)

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Wed, Jan 20 - Tue, Feb 9
IND
Indianapolis Intl.
RST
Rochester Intl.
$396 Roundtrip, found 1 day ago
$396
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Jan 20 from Indianapolis Intl. to Rochester Intl., returning Tue, Feb 9, priced at $396 found 1 day ago
Delta
Fri, Dec 11 - Sat, Dec 19
ORD
O'Hare Intl.
RST
Rochester Intl.
$398 Roundtrip, found 4 days ago
$398
Roundtrip
found 4 days ago
Select Delta flight, departing Fri, Dec 11 from O'Hare Intl. to Rochester Intl., returning Sat, Dec 19, priced at $398 found 4 days ago
Delta
Mon, Nov 16 - Mon, Nov 23
DTW
Detroit Metropolitan Wayne County
RST
Rochester Intl.
$439 Roundtrip, found 18 hours ago
$439
Roundtrip
found 18 hours ago
Select Delta flight, departing Mon, Nov 16 from Detroit Metropolitan Wayne County to Rochester Intl., returning Mon, Nov 23, priced at $439 found 18 hours ago
American Airlines
Sat, Dec 12 - Sat, Dec 19
ORD
O'Hare Intl.
RST
Rochester Intl.
$477 Roundtrip, found 1 hour ago
$477
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Sat, Dec 12 from O'Hare Intl. to Rochester Intl., returning Sat, Dec 19, priced at $477 found 1 hour ago