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Byron

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Byron Flights as Low as $191

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Sat, Aug 1 - Tue, Aug 4
STL
Lambert-St. Louis Intl.
RST
Rochester Intl.
$191 Roundtrip, found 2 days ago
$191
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, Aug 1 from Lambert-St. Louis Intl. to Rochester Intl., returning Tue, Aug 4, priced at $191 found 2 days ago
Delta
Tue, Aug 4 - Mon, Aug 10
STL
Lambert-St. Louis Intl.
RST
Rochester Intl.
$230 Roundtrip, found 2 days ago
$230
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Aug 4 from Lambert-St. Louis Intl. to Rochester Intl., returning Mon, Aug 10, priced at $230 found 2 days ago
Delta
Mon, Aug 3 - Sat, Aug 8
STL
Lambert-St. Louis Intl.
RST
Rochester Intl.
$238 Roundtrip, found 2 days ago
$238
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Aug 3 from Lambert-St. Louis Intl. to Rochester Intl., returning Sat, Aug 8, priced at $238 found 2 days ago
Delta
Tue, Aug 4 - Sun, Aug 9
STL
Lambert-St. Louis Intl.
RST
Rochester Intl.
$253 Roundtrip, found 2 days ago
$253
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Aug 4 from Lambert-St. Louis Intl. to Rochester Intl., returning Sun, Aug 9, priced at $253 found 2 days ago
Delta
Sat, Sep 5 - Wed, Sep 9
STL
Lambert-St. Louis Intl.
RST
Rochester Intl.
$266 Roundtrip, found 3 days ago
$266
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Sep 5 from Lambert-St. Louis Intl. to Rochester Intl., returning Wed, Sep 9, priced at $266 found 3 days ago
American Airlines
Wed, Sep 2 - Tue, Sep 15
EWR
Newark Liberty Intl. Airport
RST
Rochester Intl.
$270 Roundtrip, found 20 hours ago
$270
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Wed, Sep 2 from Newark Liberty Intl. Airport to Rochester Intl., returning Tue, Sep 15, priced at $270 found 20 hours ago
Delta
Thu, Sep 10 - Sat, Sep 12
STL
Lambert-St. Louis Intl.
RST
Rochester Intl.
$272 Roundtrip, found 3 days ago
$272
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, Sep 10 from Lambert-St. Louis Intl. to Rochester Intl., returning Sat, Sep 12, priced at $272 found 3 days ago
Delta
Tue, Aug 4 - Fri, Aug 7
STL
Lambert-St. Louis Intl.
RST
Rochester Intl.
$277 Roundtrip, found 2 days ago
$277
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Aug 4 from Lambert-St. Louis Intl. to Rochester Intl., returning Fri, Aug 7, priced at $277 found 2 days ago
Delta
Fri, Aug 7 - Mon, Aug 10
STL
Lambert-St. Louis Intl.
RST
Rochester Intl.
$278 Roundtrip, found 2 days ago
$278
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Aug 7 from Lambert-St. Louis Intl. to Rochester Intl., returning Mon, Aug 10, priced at $278 found 2 days ago
Delta
Mon, Aug 3 - Mon, Aug 10
STL
Lambert-St. Louis Intl.
RST
Rochester Intl.
$285 Roundtrip, found 2 days ago
$285
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Aug 3 from Lambert-St. Louis Intl. to Rochester Intl., returning Mon, Aug 10, priced at $285 found 2 days ago
Delta
Sat, Sep 5 - Fri, Sep 11
STL
Lambert-St. Louis Intl.
RST
Rochester Intl.
$287 Roundtrip, found 3 days ago
$287
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Sep 5 from Lambert-St. Louis Intl. to Rochester Intl., returning Fri, Sep 11, priced at $287 found 3 days ago
American Airlines
Tue, Jun 30 - Tue, Jul 14
DTW
Detroit Metropolitan Wayne County
RST
Rochester Intl.
$291 Roundtrip, found 6 days ago
$291
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Jun 30 from Detroit Metropolitan Wayne County to Rochester Intl., returning Tue, Jul 14, priced at $291 found 6 days ago
American Airlines
Tue, Sep 8 - Sat, Sep 12
LGA
LaGuardia
RST
Rochester Intl.
$308 Roundtrip, found 2 hours ago
$308
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Tue, Sep 8 from LaGuardia to Rochester Intl., returning Sat, Sep 12, priced at $308 found 2 hours ago
American Airlines
Wed, Aug 26 - Sun, Aug 30
BDL
Bradley Intl.
RST
Rochester Intl.
$324 Roundtrip, found 12 hours ago
$324
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Wed, Aug 26 from Bradley Intl. to Rochester Intl., returning Sun, Aug 30, priced at $324 found 12 hours ago
Delta
Thu, Jul 23 - Tue, Jul 28
FLL
Fort Lauderdale - Hollywood Intl.
RST
Rochester Intl.
$396 Roundtrip, found 17 hours ago
$396
Roundtrip
found 17 hours ago
Select Delta flight, departing Thu, Jul 23 from Fort Lauderdale - Hollywood Intl. to Rochester Intl., returning Tue, Jul 28, priced at $396 found 17 hours ago
Delta
Mon, Aug 10 - Sun, Aug 16
MYR
Myrtle Beach Intl.
RST
Rochester Intl.
$407 Roundtrip, found 11 hours ago
$407
Roundtrip
found 11 hours ago
Select Delta flight, departing Mon, Aug 10 from Myrtle Beach Intl. to Rochester Intl., returning Sun, Aug 16, priced at $407 found 11 hours ago

Cheap Flights to Byron

Fall in love at first flight with your vacation to Byron by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Byron on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Byron, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Byron

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Byron with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the RST airport.

What is the cheapest month to fly to Byron?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Byron are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Byron?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Byron.

What airport is best to fly into Byron?

When you’re planning your trip to Byron, convenience is the name of the game. Luckily, Byron Rochester Intl. Airport is nearby so you can deplane and get going on checking off everything on your Byron must-do list.

How much are flights to Byron?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Byron on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $191, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Byron?

The trick to saving a stack of cash on your flight to Byron? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $191 right now, why wait?

Byron Flight Information
Destination airport
Rochester Intl.
Destination airport IATA code
RST
Roundtrip price
$190

Last Minute Hotel Deals in Byron

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.4/10 Very Good! (2,168 reviews)
"2nd stay at Kahler Grand. Super convenient. Good bed & linens, front desk and valet parking staff are incredibly helpful. Quiet. Our room was small, but adequate. Small bathroom. Multiple restaurant options inside hotel or within easy walk. Charlton & Eisenberg are literally across the street, as ..."

Reviewed on Jun 27, 2026

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Kahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (1,607 reviews)
"Excellent hotel and customer service!"

Reviewed on Jun 29, 2026

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Kahler Inn and Suites - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3 out of 5
401 6th St Sw Rochester MN
Book a stay at this golf hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. ...
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Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw Rochester MN
Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,010 reviews)
"For some reason, they didn’t give me the king size room that I had reserved. No reason nor explanation given - i didn’t know til entering the room. Breakfast at 6:00 wasn’t ready. Oatmeal, pancake mix, hot hings tricked out between 6:00and 6:20."

Reviewed on Jun 28, 2026

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Med City Inn & Suites - Mayo Clinic Area
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 out of 5
1517 16th St Sw Rochester MN
Book a stay at this family-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.2/10 Very Good! (958 reviews)
"The beds were very comfortable. The rooms were cozy. The waterslide was a huge hit with my granddaughter. Couldn't keep her out of the pool! The only thing that was an issue was the ice machines were out of ice most of the time. We had to go from machine to machine just to get a full bucket. Overall, ..."

Reviewed on Jun 26, 2026

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Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3 out of 5
4353 Canal Pl SE Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.4/10 Good! (1,064 reviews)
"Good"

Reviewed on Jun 27, 2026

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La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,004 reviews)
"Difficult review to write The staff was excellent with me, very pleasant and accommodating The reason for my poor review is the location of the hotel situated directly beside the train tracks and crossing. Our first night 3 trains came by the hotel from 12:30am to 6:00am, each one blowing their whistle ..."

Reviewed on Jun 27, 2026

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Hyatt House Rochester/Mayo Clinic Area
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4 out of 5
101 11TH Avenue SW Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9.4/10 Exceptional! (1,004 reviews)
"The room & property was comfortable. Only dislike was the taste of the water. The machines needed new filters or maybe just the water in that area. I have stayed here many times & will continue to."

Reviewed on Jun 28, 2026

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EVEN Hotel Rochester - Mayo Clinic Area by IHG
See all 371 properties in Byron
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.