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Byron

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Byron Flights as Low as $189

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$189 Roundtrip, found 10 hours ago
$189
Roundtrip
found 10 hours ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $189 found 10 hours ago
Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$249 Roundtrip, found 10 hours ago
$249
Roundtrip
found 10 hours ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $249 found 10 hours ago
Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$259 Roundtrip, found 10 hours ago
$259
Roundtrip
found 10 hours ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $259 found 10 hours ago
Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$269 Roundtrip, found 10 hours ago
$269
Roundtrip
found 10 hours ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $269 found 10 hours ago
American Airlines
Sat, Sep 5 - Tue, Sep 15
EWR
Newark Liberty Intl. Airport
RST
Rochester Intl.
$277 Roundtrip, found 19 hours ago
$277
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Sat, Sep 5 from Newark Liberty Intl. Airport to Rochester Intl., returning Tue, Sep 15, priced at $277 found 19 hours ago
Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$284 Roundtrip, found 10 hours ago
$284
Roundtrip
found 10 hours ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $284 found 10 hours ago
Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$288 Roundtrip, found 10 hours ago
$288
Roundtrip
found 10 hours ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $288 found 10 hours ago
American Airlines
Fri, Sep 4 - Sat, Sep 12
EWR
Newark Liberty Intl. Airport
RST
Rochester Intl.
$296 Roundtrip, found 1 day ago
$296
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Sep 4 from Newark Liberty Intl. Airport to Rochester Intl., returning Sat, Sep 12, priced at $296 found 1 day ago
American Airlines
Fri, Sep 25 - Mon, Sep 28
DEN
Denver Intl.
RST
Rochester Intl.
$298 Roundtrip, found 19 hours ago
$298
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Fri, Sep 25 from Denver Intl. to Rochester Intl., returning Mon, Sep 28, priced at $298 found 19 hours ago
Delta
Fri, Sep 11 - Sun, Sep 13
LGA
LaGuardia
RST
Rochester Intl.
$308 Roundtrip, found 3 hours ago
$308
Roundtrip
found 3 hours ago
Select Delta flight, departing Fri, Sep 11 from LaGuardia to Rochester Intl., returning Sun, Sep 13, priced at $308 found 3 hours ago
American Airlines
Fri, Sep 25 - Mon, Sep 28
DEN
Denver Intl.
RST
Rochester Intl.
$313 Roundtrip, found 19 hours ago
$313
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Fri, Sep 25 from Denver Intl. to Rochester Intl., returning Mon, Sep 28, priced at $313 found 19 hours ago
American Airlines
Fri, Sep 4 - Sat, Sep 12
EWR
Newark Liberty Intl. Airport
RST
Rochester Intl.
$315 Roundtrip, found 1 day ago
$315
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Sep 4 from Newark Liberty Intl. Airport to Rochester Intl., returning Sat, Sep 12, priced at $315 found 1 day ago
American Airlines
Fri, Sep 25 - Mon, Sep 28
DEN
Denver Intl.
RST
Rochester Intl.
$319 Roundtrip, found 19 hours ago
$319
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Fri, Sep 25 from Denver Intl. to Rochester Intl., returning Mon, Sep 28, priced at $319 found 19 hours ago
American Airlines
Fri, Sep 4 - Sat, Sep 12
EWR
Newark Liberty Intl. Airport
RST
Rochester Intl.
$322 Roundtrip, found 1 day ago
$322
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Sep 4 from Newark Liberty Intl. Airport to Rochester Intl., returning Sat, Sep 12, priced at $322 found 1 day ago
Delta
Tue, Oct 6 - Fri, Oct 9
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$327 Roundtrip, found 5 days ago
$327
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Oct 6 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Fri, Oct 9, priced at $327 found 5 days ago
American Airlines
Tue, Jul 14 - Tue, Jul 21
PIA
Greater Peoria Regional
RST
Rochester Intl.
$561 Roundtrip, just found
$561
Roundtrip
just found
Select American Airlines flight, departing Tue, Jul 14 from Greater Peoria Regional to Rochester Intl., returning Tue, Jul 21, priced at $561 just found

Cheap Flights to Byron

Fall in love at first flight with your vacation to Byron by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Byron on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Byron, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Byron

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Byron with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the RST airport.

What is the cheapest month to fly to Byron?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Byron are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Byron?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Byron.

What airport is best to fly into Byron?

When you’re planning your trip to Byron, convenience is the name of the game. Luckily, Byron Rochester Intl. Airport is nearby so you can deplane and get going on checking off everything on your Byron must-do list.

How much are flights to Byron?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Byron on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $189, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Byron?

The trick to saving a stack of cash on your flight to Byron? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $189 right now, why wait?

Byron Flight Information
Destination airport
Rochester Intl.
Destination airport IATA code
RST
Roundtrip price
$188

Last Minute Hotel Deals in Byron

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.4/10 Very Good! (2,200 reviews)
"After reading some prior reviews, I was nervous about our stay. However, guest services checked us in and made sure it was ok if we were in the same side as the plaza as there was music until 9pm and it may be a little loud. That wasn't a problem for us and the music wasn’t loud. Our bathroom was ..."

Reviewed on Jul 11, 2026

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Kahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (1,621 reviews)
"Rooms had an odor to them that wasn’t appealing, outlets were scarce."

Reviewed on Jul 10, 2026

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Kahler Inn and Suites - Mayo Clinic Area
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 out of 5
1517 16th St Sw Rochester MN
Book a stay at this family-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.2/10 Very Good! (983 reviews)
"The room itself was a good size, but the humidity was unbearable. It was so damp that even the bed sheets felt wet. I left my suitcase open overnight, and by the next morning all of my clothes felt humid and had developed a musty smell after just one night. The rooms are carpeted, and because of ..."

Reviewed on Jul 10, 2026

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Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3 out of 5
401 6th St Sw Rochester MN
Book a stay at this golf hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. ...
8.6/10 Excellent! (1,015 reviews)
"Dedicated gluten free kitchen for dining at Twig restaurant"

Reviewed on Jul 11, 2026

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Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw Rochester MN
Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,015 reviews)
"No one at front desk to check in. Took an hour. And the restaurant next door did not honor the discount for the property."

Reviewed on Jul 11, 2026

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Med City Inn & Suites - Mayo Clinic Area
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S Rochester MN
Book a stay at this spa hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful staff in our ...
8/10 Very Good! (1,384 reviews)
"Ok"

Reviewed on Jul 11, 2026

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AmericInn by Wyndham Rochester Near Mayo Clinic
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4 out of 5
101 11TH Avenue SW Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9.4/10 Exceptional! (1,018 reviews)
"Great staff and guest"

Reviewed on Jul 10, 2026

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EVEN Hotel Rochester - Mayo Clinic Area by IHG
Hampton Inn Rochester-South

Hampton Inn Rochester-South

2.5 out of 5
1755 S Broadway Rochester MN
Stay at this hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,009 reviews)
"I stayed here two nights while preparing for surgery on the third day. Our room was clean and quiet at night. Air conditioning worked well. Staff was very pleasant. Breakfast was typical, offering basic protein and carbohydrate choices. I met several other individuals connected with Mayo’s exemplary ..."

Reviewed on Jul 7, 2026

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Hampton Inn Rochester-South
See all 377 properties in Byron
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.