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Byron

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Byron Flights as Low as $212

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$212 Roundtrip, found 6 hours ago
$212
Roundtrip
found 6 hours ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $212 found 6 hours ago
Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$242 Roundtrip, found 6 hours ago
$242
Roundtrip
found 6 hours ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $242 found 6 hours ago
Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$283 Roundtrip, found 6 hours ago
$283
Roundtrip
found 6 hours ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $283 found 6 hours ago
Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$293 Roundtrip, found 6 hours ago
$293
Roundtrip
found 6 hours ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $293 found 6 hours ago
Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$303 Roundtrip, found 6 hours ago
$303
Roundtrip
found 6 hours ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $303 found 6 hours ago
American Airlines
Sat, Sep 5 - Tue, Sep 15
EWR
Newark Liberty Intl. Airport
RST
Rochester Intl.
$303 Roundtrip, found 6 hours ago
$303
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Sat, Sep 5 from Newark Liberty Intl. Airport to Rochester Intl., returning Tue, Sep 15, priced at $303 found 6 hours ago
Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$308 Roundtrip, found 6 hours ago
$308
Roundtrip
found 6 hours ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $308 found 6 hours ago
Delta
Tue, Sep 29 - Tue, Oct 6
MEM
Memphis Intl.
RST
Rochester Intl.
$308 Roundtrip, found 6 hours ago
$308
Roundtrip
found 6 hours ago
Select Delta flight, departing Tue, Sep 29 from Memphis Intl. to Rochester Intl., returning Tue, Oct 6, priced at $308 found 6 hours ago
Delta
Tue, Sep 15 - Mon, Sep 28
DEN
Denver Intl.
RST
Rochester Intl.
$313 Roundtrip, found 6 hours ago
$313
Roundtrip
found 6 hours ago
Select Delta flight, departing Tue, Sep 15 from Denver Intl. to Rochester Intl., returning Mon, Sep 28, priced at $313 found 6 hours ago
Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$313 Roundtrip, found 6 hours ago
$313
Roundtrip
found 6 hours ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $313 found 6 hours ago
American Airlines
Tue, Sep 15 - Mon, Sep 28
DEN
Denver Intl.
RST
Rochester Intl.
$318 Roundtrip, found 6 hours ago
$318
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Tue, Sep 15 from Denver Intl. to Rochester Intl., returning Mon, Sep 28, priced at $318 found 6 hours ago
American Airlines
Sat, Sep 5 - Sat, Sep 12
EWR
Newark Liberty Intl. Airport
RST
Rochester Intl.
$320 Roundtrip, found 6 hours ago
$320
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Sat, Sep 5 from Newark Liberty Intl. Airport to Rochester Intl., returning Sat, Sep 12, priced at $320 found 6 hours ago
Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$323 Roundtrip, found 6 hours ago
$323
Roundtrip
found 6 hours ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $323 found 6 hours ago
Delta
Wed, Sep 9 - Mon, Sep 28
DEN
Denver Intl.
RST
Rochester Intl.
$327 Roundtrip, found 6 hours ago
$327
Roundtrip
found 6 hours ago
Select Delta flight, departing Wed, Sep 9 from Denver Intl. to Rochester Intl., returning Mon, Sep 28, priced at $327 found 6 hours ago
American Airlines
Sat, Sep 5 - Fri, Sep 11
EWR
Newark Liberty Intl. Airport
RST
Rochester Intl.
$329 Roundtrip, found 6 hours ago
$329
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Sat, Sep 5 from Newark Liberty Intl. Airport to Rochester Intl., returning Fri, Sep 11, priced at $329 found 6 hours ago
American Airlines
Sun, Sep 6 - Thu, Sep 10
SDF
Louisville Intl.
RST
Rochester Intl.
$356 Roundtrip, found 6 hours ago
$356
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Sun, Sep 6 from Louisville Intl. to Rochester Intl., returning Thu, Sep 10, priced at $356 found 6 hours ago

Cheap Flights to Byron

Fall in love at first flight with your vacation to Byron by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Byron on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Byron, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Byron

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Byron with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the RST airport.

What is the cheapest month to fly to Byron?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Byron are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Byron?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Byron.

What airport is best to fly into Byron?

When you’re planning your trip to Byron, convenience is the name of the game. Luckily, Byron Rochester Intl. Airport is nearby so you can deplane and get going on checking off everything on your Byron must-do list.

How much are flights to Byron?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Byron on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $212, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Byron?

The trick to saving a stack of cash on your flight to Byron? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $212 right now, why wait?

Byron Flight Information
Destination airport
Rochester Intl.
Destination airport IATA code
RST
Roundtrip price
$211

Last Minute Hotel Deals in Byron

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
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Kahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,688 reviews)
"The major problem we encountered during our stay was that electronic keys were not getting us into the room. It took 4 attempts to get an electronic keep to work!"

Reviewed on Aug 25, 2026

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Kahler Inn and Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw Rochester MN
Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
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EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4 out of 5
101 11TH Avenue SW Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
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EVEN Hotel Rochester - Mayo Clinic Area by IHG
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 out of 5
1517 16th St Sw Rochester MN
Book a stay at this family-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
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Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S Rochester MN
Book a stay at this spa hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful staff in our ...
8/10 Very Good! (1,452 reviews)
"When we arrived in our room, we discovered that the refrigerator had not been checked during the cleaning process, because there was food in there and the freezer had completely frozen shut. The fridge /freezer was unusable. Instead of replacing it, they just defrosted it, and said it was fine. The ..."

Reviewed on Aug 26, 2026

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AmericInn by Wyndham Rochester Near Mayo Clinic
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3 out of 5
401 6th St Sw Rochester MN
Book a stay at this golf hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. ...
8.6/10 Excellent! (1,022 reviews)
"We loved our stay! Staff was excellent, we will be back"

Reviewed on Aug 25, 2026

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Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and ...
8.8/10 Excellent! (1,007 reviews)
"This is my first time staying at Hotel Indigo. The staff was amazing. I had to keep adding nights and they were so accommodating. The room was just right. It was clean , well stocked and easy access to the Mayo Clinic. I really liked the front desk people. Super friendly and helpful. Love the attached ..."

Reviewed on Aug 23, 2026

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Hotel Indigo Rochester – Mayo Clinic Area by IHG
See all 382 properties in Byron
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.