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Byron

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Byron Flights as Low as $189

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$189 Roundtrip, found 1 day ago
$189
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $189 found 1 day ago
Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$259 Roundtrip, found 1 day ago
$259
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $259 found 1 day ago
Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$269 Roundtrip, found 1 day ago
$269
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $269 found 1 day ago
Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$274 Roundtrip, found 1 day ago
$274
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $274 found 1 day ago
Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$279 Roundtrip, found 1 day ago
$279
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $279 found 1 day ago
Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$284 Roundtrip, found 1 day ago
$284
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $284 found 1 day ago
American Airlines
Sat, Jul 25 - Tue, Jul 28
ATL
Hartsfield-Jackson Atlanta Intl.
RST
Rochester Intl.
$305 Roundtrip, found 1 day ago
$305
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Jul 25 from Hartsfield-Jackson Atlanta Intl. to Rochester Intl., returning Tue, Jul 28, priced at $305 found 1 day ago
Delta
Tue, Sep 8 - Sat, Sep 12
LGA
LaGuardia
RST
Rochester Intl.
$308 Roundtrip, found 5 hours ago
$308
Roundtrip
found 5 hours ago
Select Delta flight, departing Tue, Sep 8 from LaGuardia to Rochester Intl., returning Sat, Sep 12, priced at $308 found 5 hours ago
Delta
Fri, Oct 9 - Mon, Oct 12
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$319 Roundtrip, found 1 day ago
$319
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Oct 9 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Mon, Oct 12, priced at $319 found 1 day ago
Delta
Sat, Aug 22 - Tue, Aug 25
LGA
LaGuardia
RST
Rochester Intl.
$333 Roundtrip, found 5 days ago
$333
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Aug 22 from LaGuardia to Rochester Intl., returning Tue, Aug 25, priced at $333 found 5 days ago
Delta
Tue, Sep 8 - Sat, Sep 12
LGA
LaGuardia
RST
Rochester Intl.
$358 Roundtrip, found 5 hours ago
$358
Roundtrip
found 5 hours ago
Select Delta flight, departing Tue, Sep 8 from LaGuardia to Rochester Intl., returning Sat, Sep 12, priced at $358 found 5 hours ago
American Airlines
Tue, Sep 8 - Sat, Sep 12
LGA
LaGuardia
RST
Rochester Intl.
$371 Roundtrip, found 5 hours ago
$371
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, Sep 8 from LaGuardia to Rochester Intl., returning Sat, Sep 12, priced at $371 found 5 hours ago
American Airlines
Tue, Jul 28 - Wed, Aug 5
PDX
Portland Intl.
RST
Rochester Intl.
$372 Roundtrip, found 1 day ago
$372
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jul 28 from Portland Intl. to Rochester Intl., returning Wed, Aug 5, priced at $372 found 1 day ago
Delta
Tue, Oct 6 - Fri, Oct 9
MSP
Minneapolis - St. Paul Intl.
RST
Rochester Intl.
$387 Roundtrip, found 6 days ago
$387
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Oct 6 from Minneapolis - St. Paul Intl. to Rochester Intl., returning Fri, Oct 9, priced at $387 found 6 days ago
Delta
Tue, Sep 8 - Sat, Sep 12
LGA
LaGuardia
RST
Rochester Intl.
$388 Roundtrip, found 5 hours ago
$388
Roundtrip
found 5 hours ago
Select Delta flight, departing Tue, Sep 8 from LaGuardia to Rochester Intl., returning Sat, Sep 12, priced at $388 found 5 hours ago
Delta
Tue, Sep 8 - Sat, Sep 12
LGA
LaGuardia
RST
Rochester Intl.
$392 Roundtrip, found 5 hours ago
$392
Roundtrip
found 5 hours ago
Select Delta flight, departing Tue, Sep 8 from LaGuardia to Rochester Intl., returning Sat, Sep 12, priced at $392 found 5 hours ago

Cheap Flights to Byron

Fall in love at first flight with your vacation to Byron by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Byron on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Byron, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Byron

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Byron with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the RST airport.

What is the cheapest month to fly to Byron?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Byron are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Byron?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Byron.

What airport is best to fly into Byron?

When you’re planning your trip to Byron, convenience is the name of the game. Luckily, Byron Rochester Intl. Airport is nearby so you can deplane and get going on checking off everything on your Byron must-do list.

How much are flights to Byron?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Byron on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $189, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Byron?

The trick to saving a stack of cash on your flight to Byron? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $189 right now, why wait?

Byron Flight Information
Destination airport
Rochester Intl.
Destination airport IATA code
RST
Roundtrip price
$188

Last Minute Hotel Deals in Byron

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.4/10 Very Good! (2,168 reviews)
"2nd stay at Kahler Grand. Super convenient. Good bed & linens, front desk and valet parking staff are incredibly helpful. Quiet. Our room was small, but adequate. Small bathroom. Multiple restaurant options inside hotel or within easy walk. Charlton & Eisenberg are literally across the street, as ..."

Reviewed on Jun 27, 2026

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Kahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (1,606 reviews)
"Clean, breakfast good, can walk to favorite restaurant"

Reviewed on Jun 28, 2026

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Kahler Inn and Suites - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3 out of 5
401 6th St Sw Rochester MN
Book a stay at this golf hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. ...
8.6/10 Excellent! (1,006 reviews)
"This hotel was a good stay. I cannot say enough amazin"

Reviewed on Jun 28, 2026

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Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw Rochester MN
Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,009 reviews)
"Location is nice for running. The gym equipment was only 2 pieces but was well maintained. The key card stopped working 4x in 3 days, and of course it’s when you have a lot in your hands and walking all the way to the front desk is inconvenient. The internet stopped working several times in the middle ..."

Reviewed on Jun 28, 2026

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Med City Inn & Suites - Mayo Clinic Area
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 out of 5
1517 16th St Sw Rochester MN
Book a stay at this family-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.2/10 Very Good! (958 reviews)
"The beds were very comfortable. The rooms were cozy. The waterslide was a huge hit with my granddaughter. Couldn't keep her out of the pool! The only thing that was an issue was the ice machines were out of ice most of the time. We had to go from machine to machine just to get a full bucket. Overall, ..."

Reviewed on Jun 26, 2026

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Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3 out of 5
4353 Canal Pl SE Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.4/10 Good! (1,064 reviews)
"Good"

Reviewed on Jun 27, 2026

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La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,004 reviews)
"Difficult review to write The staff was excellent with me, very pleasant and accommodating The reason for my poor review is the location of the hotel situated directly beside the train tracks and crossing. Our first night 3 trains came by the hotel from 12:30am to 6:00am, each one blowing their whistle ..."

Reviewed on Jun 27, 2026

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Hyatt House Rochester/Mayo Clinic Area
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4 out of 5
101 11TH Avenue SW Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9.4/10 Exceptional! (1,003 reviews)
"The room & property was comfortable. Only dislike was the taste of the water. The machines needed new filters or maybe just the water in that area. I have stayed here many times & will continue to."

Reviewed on Jun 28, 2026

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EVEN Hotel Rochester - Mayo Clinic Area by IHG
See all 371 properties in Byron
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.