Search for Cheap Deals on
4 Star Hotels in Puerto Santa Ana

Photo by Paula Vernimmen

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking!


Featured 4 Star Puerto Santa Ana Hotels

Wyndham Guayaquil Puerto Santa Ana
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 7 min drive from U.S. Consulate General
The price is $115 per night from Feb 2 to Feb 3
$115
includes taxes & fees
Feb 2 - Feb 3
Stay at this 4.5-star luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
Wyndham Guayaquil Puerto Santa Ana
TRYP by Wyndham Guayaquil Airport
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 8 min drive from U.S. Consulate General
The price is $85 per night from Feb 2 to Feb 3
$85
includes taxes & fees
Feb 2 - Feb 3
Stay at this 4.5-star luxury hotel in Guayaquil. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the breakfast and the helpful staff in ...
TRYP by Wyndham Guayaquil Airport
Hilton Colon Guayaquil
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 7 min drive from U.S. Consulate General
The price is $123 per night from Jan 31 to Feb 1
$123
includes taxes & fees
Jan 31 - Feb 1
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
Hilton Colon Guayaquil
Save an average of 15% on thousands of hotels when you're signed in
Unipark by Oro Verde Hotels
4 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min drive from U.S. Consulate General
The price is $70 per night from Jan 25 to Jan 26
$70
includes taxes & fees
Jan 25 - Jan 26
Book a stay at this spa hotel in Guayaquil. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the comfy rooms in our ...
Unipark by Oro Verde Hotels
Grand Hotel Guayaquil, Ascend Hotel Collection
4 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min drive from U.S. Consulate General
The price is $72 per night from Feb 17 to Feb 18
$72
includes taxes & fees
Feb 17 - Feb 18
Stay at this 4-star family-friendly hotel in Guayaquil. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in ...
Grand Hotel Guayaquil, Ascend Hotel Collection
Hotel Puerto Pacifico Guayaquil Airport
4 out of 5
Fully refundableReserve now, pay when you stay
  • 9 min drive from U.S. Consulate General
The price is $79 per night from Jan 26 to Jan 27
$79
includes taxes & fees
Jan 26 - Jan 27
Stay at this 4-star family-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
Hotel Puerto Pacifico Guayaquil Airport
Hotel Palace Guayaquil
4 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min drive from U.S. Consulate General
The price is $75 per night from Jan 24 to Jan 25
$75
includes taxes & fees
Jan 24 - Jan 25
Stay at this 4-star business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Hotel Palace Guayaquil
Hotel del Parque
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 10 min drive from U.S. Consulate General
The price is $329 per night from Jan 27 to Jan 28
$329
includes taxes & fees
Jan 27 - Jan 28
Stay at this 4.5-star luxury hotel in Samborondon. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Guayaquil Historic Park and Museum ...
Hotel del Parque
Airbnb Urbanor
4 out of 5
  • 7 min drive from U.S. Consulate General
Stay at this 4-star apartment in Guayaquil. Enjoy free WiFi, a 24-hour front desk, and dry cleaning or laundry services. Popular attractions City Mall and Guayaquil ...
Airbnb Urbanor
Suitesecu Guayaquil
4.5 out of 5
  • 8 min drive from U.S. Consulate General
The price is $37 per night from Jan 24 to Jan 25
$37
includes taxes & fees
Jan 24 - Jan 25
Stay at this 4.5-star luxury aparthotel in Guayaquil. Enjoy free WiFi, free valet parking, and a 24-hour front desk. Popular attractions Mall del Sol Shopping ...
Suitesecu Guayaquil
Casa García
4 out of 5
  • 10 min drive from U.S. Consulate General
The price is $198 per night from Jan 29 to Jan 30
$198
includes taxes & fees
Jan 29 - Jan 30
Stay at this 4-star business-friendly hotel in Samborondon. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Museum of Cocoa and Chocolate ...
Casa García
Departamentos en la Garzota
4.5 out of 5
  • 8 min drive from U.S. Consulate General
The price is $32 per night from Feb 19 to Feb 20
$32
includes taxes & fees
Feb 19 - Feb 20
Stay at this 4.5-star luxury aparthotel in Guayaquil. Enjoy free WiFi, dry cleaning or laundry services, and laundry facilities. Popular attractions Mall del ...
Departamentos en la Garzota
Don't see what you're looking for?
See all available properties in Puerto Santa Ana
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4-star hotels in Puerto Santa Ana

When you want to live it up, but not bust your bank account, then there’s nothing better than a 4-star hotel in Puerto Santa Ana for your next trip. You’ll get all the amenities you can think of (and then some) at a rate within your means.

No fault in our stars

So what’s with the star rating anyway? Good question. The star rating has little to do with the price, and more to do with the amenities. 4-Star hotels in Puerto Santa Ana as well as everywhere else, usually have all those thoughtful touches that make you go “Ooh,” “Ahh,” and ”YES!” Think amenities like luxury bedding, high-end electronics, concierge service, and restaurants that make eating in a gourmet experience.

Stars that shine

You know there are as many underground spots, inviting lounges, memory-making music venues as there are stars in the sky. But you’ll need the funds to check them all off. That’s why we give you the chance to take us up on the Hotwire Hot Rate. You can snag Puerto Santa Ana 4-star hotels and still have plenty of leftover cash to paint the town whatever color you want. Filter hotels by:

  • Hotwire Hot Rate: We’ll snag you a crazy deal on a room by finding your hotel name after you book.
  • Price: You know that paying full price is for suckers? You can get a cheap 4-star hotel in Puerto Santa Ana starting at $32 per night.
  • Amenities: What makes you flip for your trip? Full-service spa? Heated pool? 24-hour room service? Get a hotel that’ll send you over the moon.

Do you deserve a swanky hotel with a ton of amenities? Yes, yes you do. And you also deserve a sweet deal on it. Book with Hotwire today and get that star-studded Puerto Santa Ana 4-star hotel and have plenty of cash left over to spend at that secret super star joint in the city.