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5 Star Hotels in Destin

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Featured 5 Star Destin Hotels

The Henderson Beach Resort & Spa
5 out of 5
Fully refundableReserve now, pay when you stay
  • 5 min drive from Destin Beaches
The price is $371 per night from Jan 5 to Jan 6
$371
includes taxes & fees
Jan 5 - Jan 6, 2025
Stay at this 5-star luxury resort in Destin. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
The Henderson Beach Resort & Spa
Palazzo del Mar 11 Bedroom Holiday Home by Five Star Properties
5 out of 5
  • 6 min drive from Destin Beaches
Stay at this 5-star luxury vacation home in Destin. Enjoy free parking, a beach locale, and balconies or patios. Popular attractions Big Kahuna's Water and Adventure ...
Palazzo del Mar 11 Bedroom Holiday Home by Five Star Properties
Capitano 7 Bedroom Holiday Home by Five Star Properties
5 out of 5
  • 7 min drive from Destin Beaches
Stay at this 5-star luxury vacation home in Destin. Enjoy free parking, a beach locale, and balconies or patios. Popular attractions Big Kahuna's Water and Adventure ...
Capitano 7 Bedroom Holiday Home by Five Star Properties
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Palazzo del Mar by Five Star Properties
5 out of 5
  • 6 min drive from Destin Beaches
Stay at this 5-star luxury vacation home in Destin. Enjoy free WiFi, free parking, and free bicycles on site. Popular attractions Big Kahuna's Water and Adventure ...
Palazzo del Mar by Five Star Properties
Millenia 7 Bedroom Holiday Home by Five Star Properties
5 out of 5
  • 7 min drive from Destin Beaches
Stay at this 5-star luxury villa in Destin. Enjoy free parking, balconies or patios, and cable TV channels. Popular attractions Big Kahuna's Water and Adventure ...
Millenia 7 Bedroom Holiday Home by Five Star Properties
Casa Esmeralda by Five Star Properties
5 out of 5
  • 7 min drive from Destin Beaches
Stay at this 5-star luxury vacation home in Destin. Enjoy free parking, private pools, and private spa tubs. Popular attractions Big Kahuna's Water and Adventure ...
Casa Esmeralda by Five Star Properties
Vista del Mare 4 Bedroom Holiday Home by Five Star Properties
5 out of 5
  • 7 min drive from Destin Beaches
Stay at this 5-star luxury vacation home in Destin. Enjoy free parking, balconies or patios, and cable TV channels. Popular attractions Big Kahuna's Water and ...
Vista del Mare 4 Bedroom Holiday Home by Five Star Properties
Stranded on a Sandbar 8 Bedroom Holiday Home by Five Star Properties
Stay at this 5-star luxury vacation home in Miramar Beach. Enjoy free parking, balconies or patios, and cable TV channels. Popular attractions Sandestin Golf ...
Stranded on a Sandbar 8 Bedroom Holiday Home by Five Star Properties
Casa de Palms 5 Bedroom Holiday Home by Five Star Properties
5 out of 5
  • 8 min drive from Destin Beaches
Stay at this 5-star luxury vacation home in Miramar Beach. Enjoy free parking, balconies or patios, and cable TV channels. Popular attractions Sandestin Golf ...
Casa de Palms 5 Bedroom Holiday Home by Five Star Properties
Modern Paradise by Five Star Properties
5 out of 5
  • 7 min drive from Destin Beaches
Stay at this 5-star luxury vacation home in Destin. Enjoy free WiFi, free parking, and a fitness center. Popular attractions Big Kahuna's Water and Adventure ...
Modern Paradise by Five Star Properties
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

5-Star Hotel in Destin

It’s time. No more meh motels and so-so stays. This vacation it’s all about living it up, and that starts with a great hotel. You want first-class service and award-winning restaurants. Well, let us introduce you to a 5-star hotel in Destin.

So nice you’ll blink twice

What makes a hotel worthy of supreme star-age? For starters, the service has to be top-notch and personalized. These hotels often have 24-hour room service, a welcome gift upon your arrival, and help you with your bags—even if you travel light.

Are they nicer? Heck yeah, they are! Most 5-star hotels have jaw-dropping aesthetics that give an authentic feel of class. And we’re not talking about that faux-gold soap dish your Aunt Tilda puts out for the guests—it’s the real deal.

Stars in your eyes

Are 5-stars hotels worth it? If you like the finer things in life, then yes, they sure are. But we also know you’re the type that likes to get your caviar on a fish stick budget. We’re right there with you, and that is why we make it easy to find the best 5-star hotel in Destin for you. Sort by:

  • Price: Want to live large, but keep that budget balanced? We got you. We have 5-star hotels starting at $371.

  • Amenities: Destin skyline view? Maybe a heated indoor pool? Looking for a Michelin-star restaurant? Search for the hotels that have the amenities you desire.

  • Hotwire Hot Rate: We’ll tell you the name of the hotel after you book, and you might just save a ton.

When you’re looking for the top 5-star hotels in Destin—but don’t want to pay top dollar—let us help you out. You can get that posh palace of your dreams, and have money left to take on Destin your way.