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Florence Flights as Low as $378

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Cheap Flights to Florence

Fall in love at first flight with your vacation to Florence by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Florence on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Florence, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Florence

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Florence with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MSL airport.

What is the cheapest month to fly to Florence?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Florence are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Florence?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Florence.

What airport is best to fly into Florence?

When you’re planning your trip to Florence, convenience is the name of the game. Luckily, Florence Northwest Alabama Regional Airport is nearby so you can deplane and get going on checking off everything on your Florence must-do list.

How much are flights to Florence?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Florence on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $378, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Florence?

The trick to saving a stack of cash on your flight to Florence? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $378 right now, why wait?

Florence Flight Information
Destination airport
Florence
Destination airport IATA code
MSL

Last Minute Hotel Deals in Florence

Renaissance Shoals Resort and Spa
Renaissance Shoals Resort and Spa
3.5 out of 5
10 Hightower Place, Florence, AL
Stay at this 3.5-star spa resort in Florence. Enjoy free parking, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (710 reviews)
"N/A"

Reviewed on May 22, 2025

Renaissance Shoals Resort and Spa
The Stricklin Hotel
The Stricklin Hotel
3.5 out of 5
317 N Court St, Florence, AL
Stay at this 3.5-star business-friendly hotel in Florence. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (696 reviews)
"Air in room was subpar. Check in was a cluster, and heard doors slamming all night long."

Reviewed on Jun 15, 2025

The Stricklin Hotel
Comfort Suites Florence Shoals Area
Comfort Suites Florence Shoals Area
2.5 out of 5
140 Matthew Paul Ct, Florence, AL
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (689 reviews)
"Rooms were clean and personal was very polite and friendly. The only downside the pool was closed but when we made our reservation we knew about this. I'm pretty sure when they are done with the renovations on the pool area will make it 10 times better"

Reviewed on May 29, 2025

Comfort Suites Florence Shoals Area
Baymont by Wyndham Florence/Muscle Shoals
Baymont by Wyndham Florence/Muscle Shoals
2.5 out of 5
115 Ana Drive, Florence, AL
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property ...
7.2/10 Good! (795 reviews)
"I always use this hotel every time I go to Florence. Very convenient."

Reviewed on Jun 6, 2025

Baymont by Wyndham Florence/Muscle Shoals
Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
2.5 out of 5
180 Etta Gray Street, Florence, AL
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (544 reviews)
Nice place to stay!
"Nice place to stay and in a great location"

Reviewed on Jun 17, 2025

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
Residence Inn Florence Marriott
Residence Inn Florence Marriott
3 out of 5
1000 Sweetwater Ave, Florence, AL
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Regency Square Mall and Children's ...
9/10 Wonderful! (308 reviews)
"The staff was so nice and the rooms were so nice and clean"

Reviewed on Jun 4, 2025

Residence Inn Florence Marriott
Hampton Inn Florence Midtown near University of North Alabama
Hampton Inn Florence Midtown near University of North Alabama
2.5 out of 5
2281 Florence Blvd, Florence, AL
Stay at this hotel in Florence. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (528 reviews)
Honors Band at UNA
"The room was very clean and spacious. We loved the bathroom. The food was great. My son loved making his own waffle. The staff was very helpful and engaging. Will definitely stay again on our next visit to UNA!"

Reviewed on May 4, 2025

Hampton Inn Florence Midtown near University of North Alabama
Budget Inn & Suites
Budget Inn & Suites
2.5 out of 5
1238 Florence Boulevard, Florence, AL
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.6/10 Good! (114 reviews)
"Have stayed here multiple times and this is my go to place to stay. The gentleman that runs it is excellent and takes good care of all his guests.. highly recommend"

Reviewed on Jun 16, 2025

Budget Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.