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Florence Flights as Low as $499

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Cheap Flights to Florence

Fall in love at first flight with your vacation to Florence by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Florence on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Florence, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Florence

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Florence with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MSL airport.

What is the cheapest month to fly to Florence?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Florence are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Florence?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Florence.

What airport is best to fly into Florence?

When you’re planning your trip to Florence, convenience is the name of the game. Luckily, Florence Northwest Alabama Regional Airport is nearby so you can deplane and get going on checking off everything on your Florence must-do list.

How much are flights to Florence?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Florence on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $499, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Florence?

The trick to saving a stack of cash on your flight to Florence? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $499 right now, why wait?

Florence Flight Information
Destination airport
Florence
Destination airport IATA code
MSL

Last Minute Hotel Deals in Florence

Renaissance Shoals Resort and Spa
Renaissance Shoals Resort and Spa
3.5 out of 5
10 Hightower Place, Florence, AL
The price is $286 per night from May 11 to May 12
$286
includes taxes & fees
May 11 - May 12
Stay at this 3.5-star spa resort in Florence. Enjoy free parking, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (701 reviews)
"Beautiful and clean"

Reviewed on May 5, 2025

Renaissance Shoals Resort and Spa
Comfort Suites Florence Shoals Area
Comfort Suites Florence Shoals Area
2.5 out of 5
140 Matthew Paul Ct, Florence, AL
The price is $143 per night from Jun 6 to Jun 7
$143
includes taxes & fees
Jun 6 - Jun 7
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (680 reviews)
"Large, very clean rooms. Very nice hotel."

Reviewed on May 4, 2025

Comfort Suites Florence Shoals Area
The Stricklin Hotel
The Stricklin Hotel
3.5 out of 5
317 N Court St, Florence, AL
The price is $218 per night from May 7 to May 8
$218
includes taxes & fees
May 7 - May 8
Stay at this 3.5-star business-friendly hotel in Florence. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (673 reviews)
Quick trip
"Great location and amazing staff at the desk. Ill request a room with a view of the street next time! Fun bars and restaurants on property or right next door as well."

Reviewed on Apr 23, 2025

The Stricklin Hotel
Baymont by Wyndham Florence/Muscle Shoals
Baymont by Wyndham Florence/Muscle Shoals
2.5 out of 5
115 Ana Drive, Florence, AL
The price is $83 per night from May 7 to May 8
$83
includes taxes & fees
May 7 - May 8
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property ...
7.4/10 Good! (778 reviews)
"The beds were very hard and uncomfortable. No blankets. Bed frame made a loud metallic popping sound when I would either get into bed or roll over."

Reviewed on May 4, 2025

Baymont by Wyndham Florence/Muscle Shoals
Hampton Inn Florence Midtown near University of North Alabama
Hampton Inn Florence Midtown near University of North Alabama
2.5 out of 5
2281 Florence Blvd, Florence, AL
The price is $159 per night from May 18 to May 19
$159
includes taxes & fees
May 18 - May 19
Stay at this hotel in Florence. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (528 reviews)
Honors Band at UNA
"The room was very clean and spacious. We loved the bathroom. The food was great. My son loved making his own waffle. The staff was very helpful and engaging. Will definitely stay again on our next visit to UNA!"

Reviewed on May 4, 2025

Hampton Inn Florence Midtown near University of North Alabama
Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
2.5 out of 5
180 Etta Gray Street, Florence, AL
The price is $124 per night from Jun 1 to Jun 2
$124
includes taxes & fees
Jun 1 - Jun 2
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (533 reviews)
"Everything was on point. Very happy."

Reviewed on Apr 21, 2025

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
Budget Inn & Suites
Budget Inn & Suites
2.5 out of 5
1238 Florence Boulevard, Florence, AL
The price is $73 per night from May 12 to May 13
$73
includes taxes & fees
May 12 - May 13
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.6/10 Good! (107 reviews)
"Privacy"

Reviewed on May 3, 2025

Budget Inn & Suites
Hampton Inn & Suites Florence-Downtown
Hampton Inn & Suites Florence-Downtown
2.5 out of 5
505 S Court St, Florence, AL
The price is $230 per night from May 8 to May 9
$230
includes taxes & fees
May 8 - May 9
Stay at this hotel in Florence. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (660 reviews)
Went the way you extra mile
"I was a bit surprised by the hotel compared to the price I paid.. I expected a little more luxury. Price was at least 30 to 40% higher than it should have been for that quality hotel. But there was a good bed and things were clean. I was most impressed with Melanie at the front desk. I arrived at ..."

Reviewed on Apr 20, 2025

Hampton Inn & Suites Florence-Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.