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Knoxville

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Knoxville Flights as Low as $78

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Fri, Apr 11 - Fri, Apr 18
DEN
Denver Intl.
DSM
Des Moines Intl.
$78 Roundtrip, found 2 days ago
$78
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Fri, Apr 11 from Denver Intl. to Des Moines Intl., returning Fri, Apr 18, priced at $78 found 2 days ago
Frontier Airlines
Fri, Apr 11 - Wed, Apr 23
DEN
Denver Intl.
DSM
Des Moines Intl.
$80 Roundtrip, found 2 days ago
$80
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Fri, Apr 11 from Denver Intl. to Des Moines Intl., returning Wed, Apr 23, priced at $80 found 2 days ago
Frontier Airlines
Fri, Apr 11 - Mon, Apr 14
DEN
Denver Intl.
DSM
Des Moines Intl.
$88 Roundtrip, found 2 days ago
$88
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Fri, Apr 11 from Denver Intl. to Des Moines Intl., returning Mon, Apr 14, priced at $88 found 2 days ago
Frontier Airlines
Mon, Apr 14 - Fri, Apr 18
DEN
Denver Intl.
DSM
Des Moines Intl.
$108 Roundtrip, found 4 days ago
$108
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Mon, Apr 14 from Denver Intl. to Des Moines Intl., returning Fri, Apr 18, priced at $108 found 4 days ago
Frontier Airlines
Mon, Apr 14 - Wed, Apr 23
DEN
Denver Intl.
DSM
Des Moines Intl.
$128 Roundtrip, found 2 days ago
$128
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Mon, Apr 14 from Denver Intl. to Des Moines Intl., returning Wed, Apr 23, priced at $128 found 2 days ago
Frontier Airlines
Mon, Mar 3 - Sun, Mar 9
DEN
Denver Intl.
DSM
Des Moines Intl.
$138 Roundtrip, found 5 days ago
$138
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Mon, Mar 3 from Denver Intl. to Des Moines Intl., returning Sun, Mar 9, priced at $138 found 5 days ago
Frontier Airlines
Tue, May 6 - Wed, May 14
SNA
John Wayne
DSM
Des Moines Intl.
$140 Roundtrip, found 20 hours ago
$140
Roundtrip
found 20 hours ago
Select Frontier Airlines flight, departing Tue, May 6 from John Wayne to Des Moines Intl., returning Wed, May 14, priced at $140 found 20 hours ago
Frontier Airlines
Fri, Apr 11 - Mon, Apr 21
DEN
Denver Intl.
DSM
Des Moines Intl.
$141 Roundtrip, found 4 days ago
$141
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Fri, Apr 11 from Denver Intl. to Des Moines Intl., returning Mon, Apr 21, priced at $141 found 4 days ago
Frontier Airlines
Fri, Apr 11 - Wed, Apr 23
DEN
Denver Intl.
DSM
Des Moines Intl.
$148 Roundtrip, found 2 days ago
$148
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Fri, Apr 11 from Denver Intl. to Des Moines Intl., returning Wed, Apr 23, priced at $148 found 2 days ago
United
Fri, Feb 14 - Mon, Feb 17
ORD
O'Hare Intl.
DSM
Des Moines Intl.
$189 Roundtrip, found 3 hours ago
$189
Roundtrip
found 3 hours ago
Select United flight, departing Fri, Feb 14 from O'Hare Intl. to Des Moines Intl., returning Mon, Feb 17, priced at $189 found 3 hours ago
Delta
Tue, Mar 11 - Mon, Mar 24
ORD
O'Hare Intl.
DSM
Des Moines Intl.
$209 Roundtrip, found 1 day ago
$209
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Mar 11 from O'Hare Intl. to Des Moines Intl., returning Mon, Mar 24, priced at $209 found 1 day ago
American Airlines
Thu, Mar 6 - Tue, Mar 11
DEN
Denver Intl.
DSM
Des Moines Intl.
$218 Roundtrip, found 2 days ago
$218
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Mar 6 from Denver Intl. to Des Moines Intl., returning Tue, Mar 11, priced at $218 found 2 days ago
Frontier Airlines
Sat, Feb 1 - Fri, Feb 7
IAH
George Bush Intercontinental
DSM
Des Moines Intl.
$259 Roundtrip, found 1 day ago
$259
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sat, Feb 1 from George Bush Intercontinental to Des Moines Intl., returning Fri, Feb 7, priced at $259 found 1 day ago
Frontier Airlines
Sat, Jan 25 - Fri, Jan 31
BOS
Logan Intl.
DSM
Des Moines Intl.
$360 Roundtrip, found 4 hours ago
$360
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Sat, Jan 25 from Logan Intl. to Des Moines Intl., returning Fri, Jan 31, priced at $360 found 4 hours ago
American Airlines
Wed, Nov 26 - Tue, Dec 2
SAT
San Antonio Intl.
DSM
Des Moines Intl.
$367 Roundtrip, found 1 day ago
$367
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Nov 26 from San Antonio Intl. to Des Moines Intl., returning Tue, Dec 2, priced at $367 found 1 day ago
Alaska Airlines
Fri, May 9 - Sun, May 11
SNA
John Wayne
DSM
Des Moines Intl.
$784 Roundtrip, found 20 hours ago
$784
Roundtrip
found 20 hours ago
Select Alaska Airlines flight, departing Fri, May 9 from John Wayne to Des Moines Intl., returning Sun, May 11, priced at $784 found 20 hours ago

Cheap Flights to Knoxville

Fall in love at first flight with your vacation to Knoxville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Knoxville on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Knoxville, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Knoxville

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Knoxville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to Knoxville?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Knoxville are in April, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Knoxville?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Knoxville.

What airport is best to fly into Knoxville?

When you’re planning your trip to Knoxville, convenience is the name of the game. Luckily, Knoxville Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your Knoxville must-do list.

How much are flights to Knoxville?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Knoxville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $78, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Knoxville?

The trick to saving a stack of cash on your flight to Knoxville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $78 right now, why wait?

Knoxville Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$78

Last Minute Hotel Deals in Knoxville

Cobblestone Hotel & Suites - Knoxville
Cobblestone Hotel & Suites - Knoxville
2.5 out of 5
1212 Eric Dr, Knoxville, IA
The price is $150 per night from Jan 26 to Jan 27
$150
includes taxes & fees
Jan 26 - Jan 27
Book a stay at this business-friendly hotel in Knoxville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (385 reviews)
"Signage for hotel stinks! We drove past the unmarked road twice! The 2 front desk women were sooo unfriendly! Only hotel ( besides Super 8) in town, so options are limited."

Reviewed on Jan 12, 2025

Cobblestone Hotel & Suites - Knoxville
Super 8 by Wyndham Knoxville
Super 8 by Wyndham Knoxville
2 out of 5
2205 N Lincoln St, Knoxville, IA
The price is $91 per night from Feb 6 to Feb 7
$91
includes taxes & fees
Feb 6 - Feb 7
Book a stay at this business-friendly motel in Knoxville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions National Sprint Car Hall of ...
6.6/10 (258 reviews)
"Perfect location to stay."

Reviewed on Sep 26, 2024

Super 8 by Wyndham Knoxville
Red Carpet Motel
Red Carpet Motel
2 out of 5
1702 North Lincoln Street, Knoxville, IA
Book a stay at this business-friendly motel in Knoxville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
5.8/10 (108 reviews)
"Yes"

Reviewed on Jul 28, 2024

Get rates
Red Carpet Motel
Charming Iowa Abode Near Knoxville Raceway!
Charming Iowa Abode Near Knoxville Raceway!
3 out of 5
Knoxville
Stay at this 3-star cottage in Knoxville. Enjoy free parking, a marina, and air conditioning. Popular attractions Peace Tree Brewing Company and National Sprint ...
8/10 Very Good! (1 review)
Nice place- would stay again
"There are no pet friendly hotels in Knoxville so we were very happy to find this pretty house for our stay when back for a family funeral. Pros: ample parking, good location, very clean, large space, nice kitchen, large yard, DISH TV, pet friendly, rapid response from owner, sleeps multiple people ..."

Reviewed on Nov 10, 2023

Get rates
Charming Iowa Abode Near Knoxville Raceway!
Links Bos Landen Hotel & Spa of Pella, Trademark by Wyndham
Links Bos Landen Hotel & Spa of Pella, Trademark by Wyndham
2.5 out of 5
2508 Bos Landen Dr, Pella, IA
The price is $89 per night from Jan 28 to Jan 29
$89
includes taxes & fees
Jan 28 - Jan 29
Book a stay at this golf hotel in Pella. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (535 reviews)
"nice rooms"

Reviewed on Jan 21, 2025

Links Bos Landen Hotel & Spa of Pella, Trademark by Wyndham
Country Inn & Suites by Radisson, Indianola, IA
Country Inn & Suites by Radisson, Indianola, IA
2.5 out of 5
501 E Trail Ridge Avenue, Indianola, IA
The price is $118 per night from Jan 31 to Feb 1
$118
includes taxes & fees
Jan 31 - Feb 1
Book a stay at this business-friendly hotel in Indianola. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (601 reviews)
"This is our regular hotel choice when staying in Indianola. Always clean and quiet"

Reviewed on Dec 29, 2024

Country Inn & Suites by Radisson, Indianola, IA
Baymont by Wyndham Pella
Baymont by Wyndham Pella
2.5 out of 5
2104 Washington St, Pella, IA
The price is $70 per night from Jan 30 to Jan 31
$70
includes taxes & fees
Jan 30 - Jan 31
Book a stay at this business-friendly hotel in Pella. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (873 reviews)
"employees were personable and worked well together"

Reviewed on Jan 21, 2025

Baymont by Wyndham Pella
AmericInn by Wyndham Newton
AmericInn by Wyndham Newton
2.5 out of 5
4401 S 22nd Avenue E, Newton, IA
The price is $95 per night from Jan 25 to Jan 26
$95
includes taxes & fees
Jan 25 - Jan 26
Book a stay at this business-friendly hotel in Newton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (389 reviews)
"The staff were very kind and hospitable. The room was spacious & clean. The shower had great water pressure & plenty of hot water. The pool & hot tub were great. All of the breakfast items were delicious except the hot food items. I feel like they had been out for awhile, but we didn’t go down for ..."

Reviewed on Jan 20, 2025

AmericInn by Wyndham Newton
See all 83 properties in Knoxville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.