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Knoxville

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Knoxville Flights as Low as $130

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Mon, Aug 18 - Thu, Aug 21
DEN
Denver Intl.
DSM
Des Moines Intl.
$130 Roundtrip, found 1 day ago
$130
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Aug 18 from Denver Intl. to Des Moines Intl., returning Thu, Aug 21, priced at $130 found 1 day ago
Frontier Airlines
Fri, Sep 12 - Sun, Sep 14
DEN
Denver Intl.
DSM
Des Moines Intl.
$133 Roundtrip, found 1 day ago
$133
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Sep 12 from Denver Intl. to Des Moines Intl., returning Sun, Sep 14, priced at $133 found 1 day ago
United
Mon, Aug 18 - Thu, Aug 21
DEN
Denver Intl.
DSM
Des Moines Intl.
$160 Roundtrip, found 1 day ago
$160
Roundtrip
found 1 day ago
Select United flight, departing Mon, Aug 18 from Denver Intl. to Des Moines Intl., returning Thu, Aug 21, priced at $160 found 1 day ago
American Airlines
Mon, Aug 18 - Thu, Aug 21
DEN
Denver Intl.
DSM
Des Moines Intl.
$169 Roundtrip, found 1 day ago
$169
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Aug 18 from Denver Intl. to Des Moines Intl., returning Thu, Aug 21, priced at $169 found 1 day ago
Delta
Thu, Sep 11 - Thu, Sep 11
DEN
Denver Intl.
DSM
Des Moines Intl.
$191 Roundtrip, found 1 day ago
$191
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Sep 11 from Denver Intl. to Des Moines Intl., returning Thu, Sep 11, priced at $191 found 1 day ago
American Airlines
Tue, Jul 29 - Sun, Aug 3
ORD
O'Hare Intl.
DSM
Des Moines Intl.
$197 Roundtrip, found 1 day ago
$197
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jul 29 from O'Hare Intl. to Des Moines Intl., returning Sun, Aug 3, priced at $197 found 1 day ago
Bargain Flight
Mon, Aug 25 - Fri, Aug 29
PHL
Philadelphia Intl.
DSM
Des Moines Intl.
$227 Roundtrip, found 1 day ago
$227
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Mon, Aug 25 from Philadelphia Intl. to Des Moines Intl., returning Fri, Aug 29, priced at $227 found 1 day ago
Bargain Flight
Thu, Sep 11 - Wed, Sep 17
CLT
Charlotte-Douglas Intl.
DSM
Des Moines Intl.
$235 Roundtrip, found 2 hours ago
$235
Roundtrip
found 2 hours ago
Select Bargain Flight flight, departing Thu, Sep 11 from Charlotte-Douglas Intl. to Des Moines Intl., returning Wed, Sep 17, priced at $235 found 2 hours ago
Delta
Sat, Oct 18 - Tue, Oct 21
PWM
Portland Intl. Jetport
DSM
Des Moines Intl.
$257 Roundtrip, found 1 day ago
$257
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Oct 18 from Portland Intl. Jetport to Des Moines Intl., returning Tue, Oct 21, priced at $257 found 1 day ago
American Airlines
Thu, Aug 28 - Thu, Sep 11
MSO
Missoula Intl.
DSM
Des Moines Intl.
$259 Roundtrip, found 23 hours ago
$259
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Thu, Aug 28 from Missoula Intl. to Des Moines Intl., returning Thu, Sep 11, priced at $259 found 23 hours ago
Bargain Flight
Fri, Jul 25 - Tue, Jul 29
TPA
Tampa Intl.
DSM
Des Moines Intl.
$275 Roundtrip, found 1 day ago
$275
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Fri, Jul 25 from Tampa Intl. to Des Moines Intl., returning Tue, Jul 29, priced at $275 found 1 day ago
Bargain Flight
Mon, Jul 14 - Wed, Jul 16
SAT
San Antonio Intl.
DSM
Des Moines Intl.
$287 Roundtrip, found 1 day ago
$287
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Mon, Jul 14 from San Antonio Intl. to Des Moines Intl., returning Wed, Jul 16, priced at $287 found 1 day ago
Frontier Airlines
Mon, Jul 21 - Mon, Jul 28
ATL
Hartsfield-Jackson Atlanta Intl.
DSM
Des Moines Intl.
$289 Roundtrip, found 1 day ago
$289
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Jul 21 from Hartsfield-Jackson Atlanta Intl. to Des Moines Intl., returning Mon, Jul 28, priced at $289 found 1 day ago
American Airlines
Wed, Jul 30 - Wed, Aug 6
JAX
Jacksonville Intl.
DSM
Des Moines Intl.
$338 Roundtrip, found 1 day ago
$338
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Jul 30 from Jacksonville Intl. to Des Moines Intl., returning Wed, Aug 6, priced at $338 found 1 day ago
Delta
Sat, Aug 9 - Wed, Aug 13
DAL
Love Field
DSM
Des Moines Intl.
$381 Roundtrip, found 1 day ago
$381
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Aug 9 from Love Field to Des Moines Intl., returning Wed, Aug 13, priced at $381 found 1 day ago
Delta
Wed, Jul 30 - Sat, Aug 2
SRQ
Sarasota-Bradenton Intl.
DSM
Des Moines Intl.
$427 Roundtrip, found 11 hours ago
$427
Roundtrip
found 11 hours ago
Select Delta flight, departing Wed, Jul 30 from Sarasota-Bradenton Intl. to Des Moines Intl., returning Sat, Aug 2, priced at $427 found 11 hours ago

Cheap Flights to Knoxville

Fall in love at first flight with your vacation to Knoxville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Knoxville on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Knoxville, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Knoxville

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Knoxville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to Knoxville?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Knoxville are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Knoxville?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 12 to choose from for your flight to Knoxville.

What airport is best to fly into Knoxville?

When you’re planning your trip to Knoxville, convenience is the name of the game. Luckily, Knoxville Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your Knoxville must-do list.

How much are flights to Knoxville?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Knoxville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $130, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Knoxville?

The trick to saving a stack of cash on your flight to Knoxville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $130 right now, why wait?

Knoxville Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$130

Last Minute Hotel Deals in Knoxville

Cobblestone Hotel & Suites - Knoxville
Cobblestone Hotel & Suites - Knoxville
2.5 out of 5
1212 Eric Dr, Knoxville, IA
Book a stay at this business-friendly hotel in Knoxville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (426 reviews)
"Got there late. Easy check in. Secure"

Reviewed on Jul 2, 2025

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Cobblestone Hotel & Suites - Knoxville
Super 8 by Wyndham Knoxville
Super 8 by Wyndham Knoxville
2 out of 5
2205 N Lincoln St, Knoxville, IA
Book a stay at this business-friendly motel in Knoxville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions National Sprint Car Hall of ...
6.6/10 (278 reviews)
"The shower head did not work properly because water was continually running somewhere behind the wall causing very low pressure."

Reviewed on Jun 16, 2025

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Super 8 by Wyndham Knoxville
Charming Iowa Abode Near Knoxville Raceway!
Charming Iowa Abode Near Knoxville Raceway!
3 out of 5
Knoxville
Stay at this 3-star cottage in Knoxville. Enjoy free parking, a marina, and air conditioning. Popular attractions National Sprint Car Hall of Fame and Knoxville ...
Nice place- would stay again
"There are no pet friendly hotels in Knoxville so we were very happy to find this pretty house for our stay when back for a family funeral. Pros: ample parking, good location, very clean, large space, nice kitchen, large yard, DISH TV, pet friendly, rapid response from owner, sleeps multiple people ..."

Reviewed on Nov 10, 2023

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Charming Iowa Abode Near Knoxville Raceway!
Hot Tub, Water Access: Cabin Near Lake Red Rock!
Hot Tub, Water Access: Cabin Near Lake Red Rock!
3 out of 5
Knoxville
Stay at this 3-star cottage in Knoxville. Enjoy free parking, balconies, and air conditioning. Popular attractions Bos Landen Golf Club and Lake Red Rock are ...
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Hot Tub, Water Access: Cabin Near Lake Red Rock!
Links Bos Landen Hotel & Spa of Pella, Trademark by Wyndham
Links Bos Landen Hotel & Spa of Pella, Trademark by Wyndham
2.5 out of 5
2508 Bos Landen Dr, Pella, IA
Book a stay at this golf hotel in Pella. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.4/10 Very Good! (588 reviews)
"Beautiful hotel, friendly staff, clean, great breakfast with many choices including eggs and meat."

Reviewed on Jul 3, 2025

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Links Bos Landen Hotel & Spa of Pella, Trademark by Wyndham
Country Inn & Suites by Radisson, Indianola, IA
Country Inn & Suites by Radisson, Indianola, IA
2.5 out of 5
501 E Trail Ridge Avenue, Indianola, IA
Book a stay at this business-friendly hotel in Indianola. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (644 reviews)
"Everything was really nice except the breakfast. Free breakfast with very unhealthy choices"

Reviewed on Jul 6, 2025

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Country Inn & Suites by Radisson, Indianola, IA
Days Inn by Wyndham Newton
Days Inn by Wyndham Newton
2 out of 5
1605 W 19th St S, Newton, IA
Book a stay at this business-friendly hotel in Newton. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Jasper County Historical Museum ...
7.4/10 Good! (491 reviews)
Great no frills hotel!
"Great basic room- everything was clean and in good working order. Great hotel for the price! Breakfast was pretty slim, but still well maintained, and we were thankful for what they did have. Would definitely stay again."

Reviewed on Jul 4, 2025

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Days Inn by Wyndham Newton
Baymont by Wyndham Pella
Baymont by Wyndham Pella
2.5 out of 5
2104 Washington St, Pella, IA
Book a stay at this business-friendly hotel in Pella. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (940 reviews)
"It was very clean but I thought the building could be updated."

Reviewed on Jul 7, 2025

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Baymont by Wyndham Pella
See all 100 properties in Knoxville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.