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Knoxville

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Knoxville Flights as Low as $119

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, May 14 - Sat, May 24
DEN
Denver Intl.
DSM
Des Moines Intl.
$119 Roundtrip, found 6 days ago
$119
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Wed, May 14 from Denver Intl. to Des Moines Intl., returning Sat, May 24, priced at $119 found 6 days ago
Delta
Mon, May 19 - Wed, May 28
LAS
Harry Reid Intl.
DSM
Des Moines Intl.
$221 Roundtrip, found 1 day ago
$221
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, May 19 from Harry Reid Intl. to Des Moines Intl., returning Wed, May 28, priced at $221 found 1 day ago
Frontier Airlines
Wed, Apr 23 - Wed, Apr 30
DCA
Ronald Reagan Washington National
DSM
Des Moines Intl.
$248 Roundtrip, found 19 hours ago
$248
Roundtrip
found 19 hours ago
Select Frontier Airlines flight, departing Wed, Apr 23 from Ronald Reagan Washington National to Des Moines Intl., returning Wed, Apr 30, priced at $248 found 19 hours ago
Frontier Airlines
Sun, Mar 30 - Mon, Apr 7
IND
Indianapolis Intl.
DSM
Des Moines Intl.
$249 Roundtrip, found 1 day ago
$249
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Mar 30 from Indianapolis Intl. to Des Moines Intl., returning Mon, Apr 7, priced at $249 found 1 day ago
Delta
Fri, Apr 18 - Tue, Apr 22
ABE
Lehigh Valley Intl.
DSM
Des Moines Intl.
$261 Roundtrip, found 14 hours ago
$261
Roundtrip
found 14 hours ago
Select Delta flight, departing Fri, Apr 18 from Lehigh Valley Intl. to Des Moines Intl., returning Tue, Apr 22, priced at $261 found 14 hours ago
Frontier Airlines
Sat, Mar 29 - Fri, Apr 4
ELP
El Paso Intl.
DSM
Des Moines Intl.
$280 Roundtrip, found 17 hours ago
$280
Roundtrip
found 17 hours ago
Select Frontier Airlines flight, departing Sat, Mar 29 from El Paso Intl. to Des Moines Intl., returning Fri, Apr 4, priced at $280 found 17 hours ago
Frontier Airlines
Mon, Apr 14 - Fri, Apr 18
ONT
Los Angeles - Ontario Intl.
DSM
Des Moines Intl.
$310 Roundtrip, found 2 days ago
$310
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Mon, Apr 14 from Los Angeles - Ontario Intl. to Des Moines Intl., returning Fri, Apr 18, priced at $310 found 2 days ago
Frontier Airlines
Fri, Mar 28 - Mon, Mar 31
MCO
Orlando Intl.
DSM
Des Moines Intl.
$311 Roundtrip, found 11 hours ago
$311
Roundtrip
found 11 hours ago
Select Frontier Airlines flight, departing Fri, Mar 28 from Orlando Intl. to Des Moines Intl., returning Mon, Mar 31, priced at $311 found 11 hours ago
Delta
Sat, Mar 29 - Tue, Apr 1
HSV
Huntsville Intl.
DSM
Des Moines Intl.
$325 Roundtrip, found 14 hours ago
$325
Roundtrip
found 14 hours ago
Select Delta flight, departing Sat, Mar 29 from Huntsville Intl. to Des Moines Intl., returning Tue, Apr 1, priced at $325 found 14 hours ago
Frontier Airlines
Fri, Apr 11 - Sat, Apr 19
LAX
Los Angeles Intl.
DSM
Des Moines Intl.
$330 Roundtrip, found 2 days ago
$330
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Fri, Apr 11 from Los Angeles Intl. to Des Moines Intl., returning Sat, Apr 19, priced at $330 found 2 days ago
Delta
Sat, May 17 - Tue, May 20
SAN
San Diego Intl.
DSM
Des Moines Intl.
$336 Roundtrip, found 16 hours ago
$336
Roundtrip
found 16 hours ago
Select Delta flight, departing Sat, May 17 from San Diego Intl. to Des Moines Intl., returning Tue, May 20, priced at $336 found 16 hours ago
United
Fri, Aug 1 - Sat, Aug 9
SMF
Sacramento Intl.
DSM
Des Moines Intl.
$372 Roundtrip, found 9 hours ago
$372
Roundtrip
found 9 hours ago
Select United flight, departing Fri, Aug 1 from Sacramento Intl. to Des Moines Intl., returning Sat, Aug 9, priced at $372 found 9 hours ago
American Airlines
Fri, Sep 5 - Sun, Sep 7
CLD
McClellan-Palomar
DSM
Des Moines Intl.
$407 Roundtrip, found 9 hours ago
$407
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Fri, Sep 5 from McClellan-Palomar to Des Moines Intl., returning Sun, Sep 7, priced at $407 found 9 hours ago
Delta
Sat, Mar 29 - Tue, Apr 1
BHM
Birmingham Intl.
DSM
Des Moines Intl.
$504 Roundtrip, found 14 hours ago
$504
Roundtrip
found 14 hours ago
Select Delta flight, departing Sat, Mar 29 from Birmingham Intl. to Des Moines Intl., returning Tue, Apr 1, priced at $504 found 14 hours ago
United
Wed, May 21 - Wed, May 28
COD
Yellowstone Regional
DSM
Des Moines Intl.
$583 Roundtrip, found 1 day ago
$583
Roundtrip
found 1 day ago
Select United flight, departing Wed, May 21 from Yellowstone Regional to Des Moines Intl., returning Wed, May 28, priced at $583 found 1 day ago
Lufthansa
Fri, May 16 - Tue, May 27
NBO
Jomo Kenyatta Intl.
DSM
Des Moines Intl.
$1,317 Roundtrip, found 19 hours ago
$1,317
Roundtrip
found 19 hours ago
Select Lufthansa flight, departing Fri, May 16 from Jomo Kenyatta Intl. to Des Moines Intl., returning Tue, May 27, priced at $1,317 found 19 hours ago

Cheap Flights to Knoxville

Fall in love at first flight with your vacation to Knoxville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Knoxville on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Knoxville, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Knoxville

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Knoxville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to Knoxville?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Knoxville are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Knoxville?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Knoxville.

What airport is best to fly into Knoxville?

When you’re planning your trip to Knoxville, convenience is the name of the game. Luckily, Knoxville Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your Knoxville must-do list.

How much are flights to Knoxville?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Knoxville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $119, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Knoxville?

The trick to saving a stack of cash on your flight to Knoxville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $119 right now, why wait?

Knoxville Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$118

Last Minute Hotel Deals in Knoxville

Cobblestone Hotel & Suites - Knoxville
Cobblestone Hotel & Suites - Knoxville
2.5 out of 5
1212 Eric Dr, Knoxville, IA
The price is $100 per night from Mar 31 to Apr 1
$100
includes taxes & fees
Mar 31 - Apr 1
Book a stay at this business-friendly hotel in Knoxville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (393 reviews)
"Channels on tv kept freezing, or saying we be right back,annoying."

Reviewed on Mar 25, 2025

Cobblestone Hotel & Suites - Knoxville
Super 8 by Wyndham Knoxville
Super 8 by Wyndham Knoxville
2 out of 5
2205 N Lincoln St, Knoxville, IA
The price is $80 per night from Mar 27 to Mar 28
$80
includes taxes & fees
Mar 27 - Mar 28
Book a stay at this business-friendly motel in Knoxville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions National Sprint Car Hall of ...
6.6/10 (260 reviews)
"Very clean and modern rooms. Extra blankets in the room would have been nice."

Reviewed on Mar 5, 2025

Super 8 by Wyndham Knoxville
Charming Iowa Abode Near Knoxville Raceway!
Charming Iowa Abode Near Knoxville Raceway!
3 out of 5
Knoxville
Stay at this 3-star cottage in Knoxville. Enjoy free parking, a marina, and air conditioning. Popular attractions Peace Tree Brewing Company and National Sprint ...
8/10 Very Good! (1 review)
Nice place- would stay again
"There are no pet friendly hotels in Knoxville so we were very happy to find this pretty house for our stay when back for a family funeral. Pros: ample parking, good location, very clean, large space, nice kitchen, large yard, DISH TV, pet friendly, rapid response from owner, sleeps multiple people ..."

Reviewed on Nov 10, 2023

Get rates
Charming Iowa Abode Near Knoxville Raceway!
Red Carpet Motel
Red Carpet Motel
2 out of 5
1702 North Lincoln Street, Knoxville, IA
Book a stay at this business-friendly motel in Knoxville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
5.8/10 (108 reviews)
"Yes"

Reviewed on Jul 28, 2024

Get rates
Red Carpet Motel
EverSpring Inn & Suites
EverSpring Inn & Suites
2.5 out of 5
2401 A Ave West, Oskaloosa, IA
The price is $111 per night from Mar 27 to Mar 28
$111
includes taxes & fees
Mar 27 - Mar 28
Book a stay at this business-friendly hotel in Oskaloosa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (554 reviews)
"I Will use again when in the area."

Reviewed on Mar 16, 2025

EverSpring Inn & Suites
Country Inn & Suites by Radisson, Indianola, IA
Country Inn & Suites by Radisson, Indianola, IA
2.5 out of 5
501 E Trail Ridge Avenue, Indianola, IA
The price is $132 per night from Mar 28 to Mar 29
$132
includes taxes & fees
Mar 28 - Mar 29
Book a stay at this business-friendly hotel in Indianola. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (606 reviews)
"The staff was super accommodating and friendly rooms were super clean. Everything looked great. Had a wonderful day. Will be checking out tomorrow."

Reviewed on Mar 6, 2025

Country Inn & Suites by Radisson, Indianola, IA
Links Bos Landen Hotel & Spa of Pella, Trademark by Wyndham
Links Bos Landen Hotel & Spa of Pella, Trademark by Wyndham
2.5 out of 5
2508 Bos Landen Dr, Pella, IA
The price is $93 per night from Mar 27 to Mar 28
$93
includes taxes & fees
Mar 27 - Mar 28
Book a stay at this golf hotel in Pella. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (542 reviews)
"The spa was so good. The room was quiet and clean"

Reviewed on Mar 22, 2025

Links Bos Landen Hotel & Spa of Pella, Trademark by Wyndham
Country Inn & Suites by Radisson, Pella, IA
Country Inn & Suites by Radisson, Pella, IA
2.5 out of 5
315 Roosevelt Road, Pella, IA
The price is $117 per night from Apr 20 to Apr 21
$117
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Pella. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (497 reviews)
"Cookies at the check in front desk. My check in person was really great . The staff was really professional and overall my room was really clean."

Reviewed on Mar 21, 2025

Country Inn & Suites by Radisson, Pella, IA
See all 83 properties in Knoxville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.