Search Cheap Flights to
Knoxville

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Knoxville Flights as Low as $121

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Tue, Mar 11 - Tue, Mar 18
BWI
Baltimore Washington Intl. Thurgood Marshall
DSM
Des Moines Intl.
$121 Roundtrip, found 1 day ago
$121
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Tue, Mar 11 from Baltimore Washington Intl. Thurgood Marshall to Des Moines Intl., returning Tue, Mar 18, priced at $121 found 1 day ago
Frontier Airlines
Mon, Mar 17 - Tue, Mar 18
BWI
Baltimore Washington Intl. Thurgood Marshall
DSM
Des Moines Intl.
$140 Roundtrip, found 1 day ago
$140
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Mar 17 from Baltimore Washington Intl. Thurgood Marshall to Des Moines Intl., returning Tue, Mar 18, priced at $140 found 1 day ago
Frontier Airlines
Fri, Mar 14 - Tue, Mar 18
BWI
Baltimore Washington Intl. Thurgood Marshall
DSM
Des Moines Intl.
$151 Roundtrip, found 1 day ago
$151
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Mar 14 from Baltimore Washington Intl. Thurgood Marshall to Des Moines Intl., returning Tue, Mar 18, priced at $151 found 1 day ago
Frontier Airlines
Mon, Mar 17 - Sat, Mar 22
BWI
Baltimore Washington Intl. Thurgood Marshall
DSM
Des Moines Intl.
$160 Roundtrip, found 1 day ago
$160
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Mar 17 from Baltimore Washington Intl. Thurgood Marshall to Des Moines Intl., returning Sat, Mar 22, priced at $160 found 1 day ago
Frontier Airlines
Fri, Mar 14 - Wed, Mar 19
BWI
Baltimore Washington Intl. Thurgood Marshall
DSM
Des Moines Intl.
$170 Roundtrip, found 2 hours ago
$170
Roundtrip
found 2 hours ago
Select Frontier Airlines flight, departing Fri, Mar 14 from Baltimore Washington Intl. Thurgood Marshall to Des Moines Intl., returning Wed, Mar 19, priced at $170 found 2 hours ago
Frontier Airlines
Fri, Mar 14 - Sat, Mar 22
BWI
Baltimore Washington Intl. Thurgood Marshall
DSM
Des Moines Intl.
$171 Roundtrip, found 1 day ago
$171
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Mar 14 from Baltimore Washington Intl. Thurgood Marshall to Des Moines Intl., returning Sat, Mar 22, priced at $171 found 1 day ago
Frontier Airlines
Fri, Mar 14 - Fri, Mar 21
BWI
Baltimore Washington Intl. Thurgood Marshall
DSM
Des Moines Intl.
$181 Roundtrip, found 1 day ago
$181
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Mar 14 from Baltimore Washington Intl. Thurgood Marshall to Des Moines Intl., returning Fri, Mar 21, priced at $181 found 1 day ago
Frontier Airlines
Tue, Apr 29 - Fri, May 9
DCA
Ronald Reagan Washington National
DSM
Des Moines Intl.
$250 Roundtrip, found 6 days ago
$250
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Tue, Apr 29 from Ronald Reagan Washington National to Des Moines Intl., returning Fri, May 9, priced at $250 found 6 days ago
Frontier Airlines
Thu, Feb 27 - Mon, Mar 3
CLT
Charlotte-Douglas Intl.
DSM
Des Moines Intl.
$284 Roundtrip, found 1 day ago
$284
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Feb 27 from Charlotte-Douglas Intl. to Des Moines Intl., returning Mon, Mar 3, priced at $284 found 1 day ago
Delta
Tue, May 13 - Tue, May 20
FLL
Fort Lauderdale - Hollywood Intl.
DSM
Des Moines Intl.
$308 Roundtrip, found 1 day ago
$308
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, May 13 from Fort Lauderdale - Hollywood Intl. to Des Moines Intl., returning Tue, May 20, priced at $308 found 1 day ago
American Airlines
Wed, Apr 30 - Tue, May 6
DCA
Ronald Reagan Washington National
DSM
Des Moines Intl.
$327 Roundtrip, found 6 days ago
$327
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Apr 30 from Ronald Reagan Washington National to Des Moines Intl., returning Tue, May 6, priced at $327 found 6 days ago
United
Wed, Apr 30 - Tue, May 6
DCA
Ronald Reagan Washington National
DSM
Des Moines Intl.
$346 Roundtrip, found 6 days ago
$346
Roundtrip
found 6 days ago
Select United flight, departing Wed, Apr 30 from Ronald Reagan Washington National to Des Moines Intl., returning Tue, May 6, priced at $346 found 6 days ago
Delta
Tue, Jun 17 - Tue, Jun 24
FWA
Fort Wayne Intl.
DSM
Des Moines Intl.
$355 Roundtrip, found 1 day ago
$355
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jun 17 from Fort Wayne Intl. to Des Moines Intl., returning Tue, Jun 24, priced at $355 found 1 day ago
Delta
Fri, Mar 7 - Mon, Mar 10
JAX
Jacksonville Intl.
DSM
Des Moines Intl.
$382 Roundtrip, found 6 days ago
$382
Roundtrip
found 6 days ago
Select Delta flight, departing Fri, Mar 7 from Jacksonville Intl. to Des Moines Intl., returning Mon, Mar 10, priced at $382 found 6 days ago
American Airlines
Tue, Mar 4 - Mon, Mar 10
RDU
Raleigh - Durham Intl.
DSM
Des Moines Intl.
$417 Roundtrip, found 18 hours ago
$417
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Tue, Mar 4 from Raleigh - Durham Intl. to Des Moines Intl., returning Mon, Mar 10, priced at $417 found 18 hours ago
Delta
Wed, Jun 11 - Tue, Jun 17
ATL
Hartsfield-Jackson Atlanta Intl.
DSM
Des Moines Intl.
$448 Roundtrip, found 6 days ago
$448
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Jun 11 from Hartsfield-Jackson Atlanta Intl. to Des Moines Intl., returning Tue, Jun 17, priced at $448 found 6 days ago

Cheap Flights to Knoxville

Fall in love at first flight with your vacation to Knoxville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Knoxville on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Knoxville, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Knoxville

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Knoxville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to Knoxville?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Knoxville are in March, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Knoxville?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Knoxville.

What airport is best to fly into Knoxville?

When you’re planning your trip to Knoxville, convenience is the name of the game. Luckily, Knoxville Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your Knoxville must-do list.

How much are flights to Knoxville?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Knoxville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $121, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Knoxville?

The trick to saving a stack of cash on your flight to Knoxville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $121 right now, why wait?

Knoxville Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$120

Last Minute Hotel Deals in Knoxville

Super 8 by Wyndham Knoxville
Super 8 by Wyndham Knoxville
2 out of 5
2205 N Lincoln St, Knoxville, IA
The price is $88 per night from Mar 2 to Mar 3
$88
includes taxes & fees
Mar 2 - Mar 3
Book a stay at this business-friendly motel in Knoxville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions National Sprint Car Hall of ...
6.6/10 (259 reviews)
"Nice and clean property"

Reviewed on Feb 7, 2025

Super 8 by Wyndham Knoxville
Cobblestone Hotel & Suites - Knoxville
Cobblestone Hotel & Suites - Knoxville
2.5 out of 5
1212 Eric Dr, Knoxville, IA
The price is $133 per night from Mar 7 to Mar 8
$133
includes taxes & fees
Mar 7 - Mar 8
Book a stay at this business-friendly hotel in Knoxville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (386 reviews)
"The property is modern and the room is nice. The front desk clerk was pleasant. Parking is very convenient."

Reviewed on Feb 13, 2025

Cobblestone Hotel & Suites - Knoxville
Charming Iowa Abode Near Knoxville Raceway!
Charming Iowa Abode Near Knoxville Raceway!
3 out of 5
Knoxville
Stay at this 3-star cottage in Knoxville. Enjoy free parking, a marina, and air conditioning. Popular attractions Peace Tree Brewing Company and National Sprint ...
8/10 Very Good! (1 review)
Nice place- would stay again
"There are no pet friendly hotels in Knoxville so we were very happy to find this pretty house for our stay when back for a family funeral. Pros: ample parking, good location, very clean, large space, nice kitchen, large yard, DISH TV, pet friendly, rapid response from owner, sleeps multiple people ..."

Reviewed on Nov 10, 2023

Get rates
Charming Iowa Abode Near Knoxville Raceway!
Red Carpet Motel
Red Carpet Motel
2 out of 5
1702 North Lincoln Street, Knoxville, IA
Book a stay at this business-friendly motel in Knoxville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
5.8/10 (108 reviews)
"Yes"

Reviewed on Jul 28, 2024

Get rates
Red Carpet Motel
Country Inn & Suites by Radisson, Indianola, IA
Country Inn & Suites by Radisson, Indianola, IA
2.5 out of 5
501 E Trail Ridge Avenue, Indianola, IA
The price is $123 per night from Feb 28 to Mar 1
$123
includes taxes & fees
Feb 28 - Mar 1
Book a stay at this business-friendly hotel in Indianola. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (604 reviews)
"More outlets outside to plug in diesel engines, would be helpful."

Reviewed on Jan 22, 2025

Country Inn & Suites by Radisson, Indianola, IA
EverSpring Inn & Suites
EverSpring Inn & Suites
2.5 out of 5
2401 A Ave West, Oskaloosa, IA
The price is $111 per night from Feb 24 to Feb 25
$111
includes taxes & fees
Feb 24 - Feb 25
Book a stay at this business-friendly hotel in Oskaloosa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (547 reviews)
"The staff was very friendly. The stay was convertible. But very disappointed at the continental breakfast. Only 2 pieces of french toast. A few biscuits, dry cereal and bread. The coffee was empty. Breakfast was at 6am. And this was at 7:25am. Sent my daughter to Casey's to bring back some warm ..."

Reviewed on Feb 6, 2025

EverSpring Inn & Suites
Baymont by Wyndham Pella
Baymont by Wyndham Pella
2.5 out of 5
2104 Washington St, Pella, IA
The price is $75 per night from Mar 4 to Mar 5
$75
includes taxes & fees
Mar 4 - Mar 5
Book a stay at this business-friendly hotel in Pella. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (882 reviews)
"Friendly staff clean clean rooms"

Reviewed on Feb 18, 2025

Baymont by Wyndham Pella
Links Bos Landen Hotel & Spa of Pella, Trademark by Wyndham
Links Bos Landen Hotel & Spa of Pella, Trademark by Wyndham
2.5 out of 5
2508 Bos Landen Dr, Pella, IA
The price is $91 per night from Feb 24 to Feb 25
$91
includes taxes & fees
Feb 24 - Feb 25
Book a stay at this golf hotel in Pella. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (537 reviews)
"nice rooms"

Reviewed on Jan 21, 2025

Links Bos Landen Hotel & Spa of Pella, Trademark by Wyndham
See all 83 properties in Knoxville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.