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Mexico

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Mexico Flights as Low as $325

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Wed, Oct 1 - Thu, Oct 9
ATL
Hartsfield-Jackson Atlanta Intl.
COU
Columbia Regional
$325 Roundtrip, found 4 days ago
$325
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Oct 1 from Hartsfield-Jackson Atlanta Intl. to Columbia Regional, returning Thu, Oct 9, priced at $325 found 4 days ago
American Airlines
Sat, Oct 11 - Fri, Oct 17
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$337 Roundtrip, found 2 days ago
$337
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Fri, Oct 17, priced at $337 found 2 days ago
American Airlines
Fri, Oct 10 - Fri, Oct 17
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$349 Roundtrip, found 4 days ago
$349
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, Oct 10 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Fri, Oct 17, priced at $349 found 4 days ago
American Airlines
Sat, Oct 11 - Fri, Oct 17
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$377 Roundtrip, found 2 days ago
$377
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Fri, Oct 17, priced at $377 found 2 days ago
American Airlines
Wed, Oct 8 - Sat, Oct 11
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$380 Roundtrip, found 2 hours ago
$380
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Wed, Oct 8 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Sat, Oct 11, priced at $380 found 2 hours ago
American Airlines
Wed, Oct 8 - Sat, Oct 11
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$386 Roundtrip, found 2 hours ago
$386
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Wed, Oct 8 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Sat, Oct 11, priced at $386 found 2 hours ago
American Airlines
Fri, Oct 10 - Fri, Oct 17
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$389 Roundtrip, found 4 days ago
$389
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, Oct 10 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Fri, Oct 17, priced at $389 found 4 days ago
American Airlines
Tue, Oct 7 - Tue, Oct 21
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$395 Roundtrip, found 5 hours ago
$395
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, Oct 7 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 21, priced at $395 found 5 hours ago
American Airlines
Sat, Oct 4 - Tue, Oct 7
ATL
Hartsfield-Jackson Atlanta Intl.
COU
Columbia Regional
$404 Roundtrip, found 17 hours ago
$404
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Sat, Oct 4 from Hartsfield-Jackson Atlanta Intl. to Columbia Regional, returning Tue, Oct 7, priced at $404 found 17 hours ago
American Airlines
Wed, Oct 8 - Sat, Oct 11
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$410 Roundtrip, found 2 hours ago
$410
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Wed, Oct 8 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Sat, Oct 11, priced at $410 found 2 hours ago
American Airlines
Wed, Oct 8 - Sat, Oct 11
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$410 Roundtrip, found 2 hours ago
$410
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Wed, Oct 8 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Sat, Oct 11, priced at $410 found 2 hours ago
American Airlines
Sat, Aug 23 - Tue, Aug 26
JFK
John F. Kennedy Intl.
COU
Columbia Regional
$430 Roundtrip, found 15 hours ago
$430
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Sat, Aug 23 from John F. Kennedy Intl. to Columbia Regional, returning Tue, Aug 26, priced at $430 found 15 hours ago
American Airlines
Sat, Aug 2 - Sat, Aug 9
JAX
Jacksonville Intl.
COU
Columbia Regional
$436 Roundtrip, found 1 day ago
$436
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Aug 2 from Jacksonville Intl. to Columbia Regional, returning Sat, Aug 9, priced at $436 found 1 day ago
United
Mon, Sep 29 - Fri, Oct 10
ATL
Hartsfield-Jackson Atlanta Intl.
COU
Columbia Regional
$446 Roundtrip, found 6 days ago
$446
Roundtrip
found 6 days ago
Select United flight, departing Mon, Sep 29 from Hartsfield-Jackson Atlanta Intl. to Columbia Regional, returning Fri, Oct 10, priced at $446 found 6 days ago
American Airlines
Thu, Aug 28 - Sun, Aug 31
GSO
Piedmont Triad Intl.
COU
Columbia Regional
$470 Roundtrip, found 19 hours ago
$470
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Thu, Aug 28 from Piedmont Triad Intl. to Columbia Regional, returning Sun, Aug 31, priced at $470 found 19 hours ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
LGA
LaGuardia
COU
Columbia Regional
$477 Roundtrip, found 15 hours ago
$477
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Wed, Aug 20 from LaGuardia to Columbia Regional, returning Wed, Aug 27, priced at $477 found 15 hours ago

Cheap Flights to Mexico

Fall in love at first flight with your vacation to Mexico by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Mexico on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Mexico, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Mexico

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Mexico with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the COU airport.

What is the cheapest month to fly to Mexico?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Mexico are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Mexico?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Mexico.

What airport is best to fly into Mexico?

When you’re planning your trip to Mexico, convenience is the name of the game. Luckily, Mexico Columbia Regional Airport is nearby so you can deplane and get going on checking off everything on your Mexico must-do list.

How much are flights to Mexico?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Mexico on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $325, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Mexico?

The trick to saving a stack of cash on your flight to Mexico? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $325 right now, why wait?

Mexico Flight Information
Destination airport
Columbia Regional
Destination airport IATA code
COU
Roundtrip price
$324

Last Minute Hotel Deals in Mexico

Capital O Amerihost Inn and Suites Mexico Hwy 54 MO

Capital O Amerihost Inn and Suites Mexico Hwy 54 MO

2.5 out of 5
900 Vance Rd, Mexico, MO
Book a stay at this business-friendly motel in Mexico. Enjoy free WiFi, free parking, and a fitness center. Popular attractions Green Estates and Teal Lake Park ...
5.4/10 (353 reviews)
"Nice place"

Reviewed on Jul 21, 2025

Get rates
Capital O Amerihost Inn and Suites Mexico Hwy 54 MO
Best Western Teal Lake Inn

Best Western Teal Lake Inn

2.5 out of 5
3602 S Clark St, Mexico, MO
Book a stay at this business-friendly hotel in Mexico. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (434 reviews)
"Simply clean and tidy. Nice and friendly staff"

Reviewed on Jul 19, 2025

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Best Western Teal Lake Inn
Days Inn by Wyndham Mexico

Days Inn by Wyndham Mexico

2 out of 5
2902 S. Clark, Mexico, MO
Stay at this hotel in Mexico. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Green Estates and Lakeview Park are located nearby.
6.8/10 (284 reviews)
"Very comfortable bed and clean room. Very nice when I asked for more coffee for my room."

Reviewed on Jun 24, 2025

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Days Inn by Wyndham Mexico
America's Value Inn Mexico

America's Value Inn Mexico

1.5 out of 5
4224 S Clark St, Mexico, MO
Stay at this motel in Mexico. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Green Estates and Teal Lake Park are located ...
5.2/10 (18 reviews)
"who ever owns this property I met him ,seems to be very humble. He needs to update this property . i dont mind paying more if everything is well maintained and welcoming."

Reviewed on Apr 6, 2025

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America's Value Inn Mexico
Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

3 out of 5
3100 Interstate 70 Dr. SE, Columbia, MO
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.6/10 Exceptional! (1,207 reviews)
"Always comfortable and pleasant"

Reviewed on Jul 23, 2025

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Drury Plaza Hotel Columbia East
Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia

3 out of 5
3101 Wingate Ct, Columbia, MO
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,122 reviews)
"Great place for trade"

Reviewed on Jul 22, 2025

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Wingate by Wyndham - Columbia
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

2.5 out of 5
817 N Keene St, Columbia, MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,548 reviews)
"Our room was clean and fresh and the bed was excellent for a good night’s rest. The breakfast area was nice and clean and we had a good a good selection for breakfast."

Reviewed on Jul 24, 2025

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Country Inn & Suites by Radisson, Columbia, MO
Ramada by Wyndham Columbia

Ramada by Wyndham Columbia

2.5 out of 5
901 Conley Rd, Columbia, MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,012 reviews)
"I love that it had an outdoor pool! And breakfast was really good!"

Reviewed on Jul 21, 2025

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Ramada by Wyndham Columbia
See all 206 properties in Mexico
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.