Search Cheap Flights to
Mexico

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Mexico Flights as Low as $377

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Fri, May 23 - Wed, May 28
BOS
Logan Intl.
COU
Columbia Regional
$377 Roundtrip, found 5 hours ago
$377
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Fri, May 23 from Logan Intl. to Columbia Regional, returning Wed, May 28, priced at $377 found 5 hours ago
American Airlines
Fri, May 23 - Wed, May 28
CMH
John Glenn Columbus Intl.
COU
Columbia Regional
$477 Roundtrip, found 5 hours ago
$477
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Fri, May 23 from John Glenn Columbus Intl. to Columbia Regional, returning Wed, May 28, priced at $477 found 5 hours ago
American Airlines
Fri, May 23 - Tue, May 27
CMH
John Glenn Columbus Intl.
COU
Columbia Regional
$487 Roundtrip, found 5 hours ago
$487
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Fri, May 23 from John Glenn Columbus Intl. to Columbia Regional, returning Tue, May 27, priced at $487 found 5 hours ago
American Airlines
Sat, May 24 - Sun, May 25
CMH
John Glenn Columbus Intl.
COU
Columbia Regional
$494 Roundtrip, found 5 hours ago
$494
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sat, May 24 from John Glenn Columbus Intl. to Columbia Regional, returning Sun, May 25, priced at $494 found 5 hours ago
American Airlines
Wed, May 21 - Sat, May 31
CMH
John Glenn Columbus Intl.
COU
Columbia Regional
$494 Roundtrip, found 5 hours ago
$494
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Wed, May 21 from John Glenn Columbus Intl. to Columbia Regional, returning Sat, May 31, priced at $494 found 5 hours ago
American Airlines
Sat, May 24 - Tue, May 27
CMH
John Glenn Columbus Intl.
COU
Columbia Regional
$504 Roundtrip, found 5 hours ago
$504
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sat, May 24 from John Glenn Columbus Intl. to Columbia Regional, returning Tue, May 27, priced at $504 found 5 hours ago
American Airlines
Fri, May 23 - Wed, May 28
CMH
John Glenn Columbus Intl.
COU
Columbia Regional
$506 Roundtrip, found 5 hours ago
$506
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Fri, May 23 from John Glenn Columbus Intl. to Columbia Regional, returning Wed, May 28, priced at $506 found 5 hours ago
American Airlines
Tue, May 20 - Tue, May 27
CMH
John Glenn Columbus Intl.
COU
Columbia Regional
$514 Roundtrip, found 5 hours ago
$514
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, May 20 from John Glenn Columbus Intl. to Columbia Regional, returning Tue, May 27, priced at $514 found 5 hours ago
American Airlines
Wed, May 21 - Thu, May 29
CMH
John Glenn Columbus Intl.
COU
Columbia Regional
$521 Roundtrip, found 5 hours ago
$521
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Wed, May 21 from John Glenn Columbus Intl. to Columbia Regional, returning Thu, May 29, priced at $521 found 5 hours ago
American Airlines
Tue, May 20 - Thu, May 29
CMH
John Glenn Columbus Intl.
COU
Columbia Regional
$532 Roundtrip, found 5 hours ago
$532
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, May 20 from John Glenn Columbus Intl. to Columbia Regional, returning Thu, May 29, priced at $532 found 5 hours ago
American Airlines
Wed, May 21 - Sun, May 25
CMH
John Glenn Columbus Intl.
COU
Columbia Regional
$532 Roundtrip, found 5 hours ago
$532
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Wed, May 21 from John Glenn Columbus Intl. to Columbia Regional, returning Sun, May 25, priced at $532 found 5 hours ago
American Airlines
Fri, May 23 - Wed, May 28
BOS
Logan Intl.
COU
Columbia Regional
$534 Roundtrip, found 5 hours ago
$534
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Fri, May 23 from Logan Intl. to Columbia Regional, returning Wed, May 28, priced at $534 found 5 hours ago
American Airlines
Sun, May 25 - Sat, May 31
BOS
Logan Intl.
COU
Columbia Regional
$535 Roundtrip, found 5 hours ago
$535
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sun, May 25 from Logan Intl. to Columbia Regional, returning Sat, May 31, priced at $535 found 5 hours ago
American Airlines
Thu, May 22 - Tue, May 27
CMH
John Glenn Columbus Intl.
COU
Columbia Regional
$543 Roundtrip, found 5 hours ago
$543
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Thu, May 22 from John Glenn Columbus Intl. to Columbia Regional, returning Tue, May 27, priced at $543 found 5 hours ago
American Airlines
Sat, May 24 - Sun, May 25
BOS
Logan Intl.
COU
Columbia Regional
$545 Roundtrip, found 5 hours ago
$545
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sat, May 24 from Logan Intl. to Columbia Regional, returning Sun, May 25, priced at $545 found 5 hours ago
American Airlines
Thu, May 22 - Thu, May 29
CMH
John Glenn Columbus Intl.
COU
Columbia Regional
$560 Roundtrip, found 5 hours ago
$560
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Thu, May 22 from John Glenn Columbus Intl. to Columbia Regional, returning Thu, May 29, priced at $560 found 5 hours ago

Cheap Flights to Mexico

Fall in love at first flight with your vacation to Mexico by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Mexico on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Mexico, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Mexico

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Mexico with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the COU airport.

What is the cheapest month to fly to Mexico?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Mexico are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Mexico?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Mexico.

What airport is best to fly into Mexico?

When you’re planning your trip to Mexico, convenience is the name of the game. Luckily, Mexico Columbia Regional Airport is nearby so you can deplane and get going on checking off everything on your Mexico must-do list.

How much are flights to Mexico?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Mexico on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $377, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Mexico?

The trick to saving a stack of cash on your flight to Mexico? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $377 right now, why wait?

Mexico Flight Information
Destination airport
Columbia Regional
Destination airport IATA code
COU
Roundtrip price
$376

Last Minute Hotel Deals in Mexico

Best Western Teal Lake Inn
Best Western Teal Lake Inn
2.5 out of 5
3602 S Clark St, Mexico, MO
The price is $112 per night from May 28 to May 29
$112
includes taxes & fees
May 28 - May 29
Book a stay at this business-friendly hotel in Mexico. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (408 reviews)
"There on business two days. Clean , decent breakfast, nice room."

Reviewed on Apr 20, 2025

Best Western Teal Lake Inn
Amerihost Inn & Suites - Mexico
Amerihost Inn & Suites - Mexico
2.5 out of 5
900 Vance Rd, Mexico, MO
The price is $73 per night from Apr 30 to May 1
$73
includes taxes & fees
Apr 30 - May 1
Book a stay at this business-friendly motel in Mexico. Enjoy free WiFi, free parking, and a fitness center. Popular attractions Green Estates and Teal Lake Park ...
5.4/10 (324 reviews)
Service was great.
"It was great just needed privacy and quiet The only issue i had was the tv. Only 8 channels worked"

Reviewed on Mar 26, 2025

Amerihost Inn & Suites - Mexico
Days Inn by Wyndham Mexico
Days Inn by Wyndham Mexico
2 out of 5
2902 S. Clark, Mexico, MO
The price is $110 per night from May 4 to May 5
$110
includes taxes & fees
May 4 - May 5
Stay at this hotel in Mexico. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Lakeview Park and Teal Lake are located nearby.
6.8/10 (277 reviews)
"Quiet clean rooms"

Reviewed on Dec 26, 2024

Days Inn by Wyndham Mexico
Budget Inn
Budget Inn
2 out of 5
1010 E Liberty St, Mexico, MO
The price is $73 per night from Apr 30 to May 1
$73
includes taxes & fees
Apr 30 - May 1
Book a stay at this business-friendly motel in Mexico. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Presser Performing Arts Center ...
"Clean Large room"

Reviewed on Mar 14, 2025

Budget Inn
Country Inn & Suites by Radisson, Columbia, MO
Country Inn & Suites by Radisson, Columbia, MO
2.5 out of 5
817 N Keene St, Columbia, MO
The price is $90 per night from May 8 to May 9
$90
includes taxes & fees
May 8 - May 9
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,479 reviews)
"Very nice place with a great hot tub! Staff was fun and professional. would stay again!"

Reviewed on Apr 27, 2025

Country Inn & Suites by Radisson, Columbia, MO
Wingate by Wyndham - Columbia
Wingate by Wyndham - Columbia
3 out of 5
3101 Wingate Ct, Columbia, MO
The price is $98 per night from May 5 to May 6
$98
includes taxes & fees
May 5 - May 6
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,075 reviews)
"The location was convenient. Everything met or exceeded my expectations."

Reviewed on Apr 25, 2025

Wingate by Wyndham - Columbia
Best Western Plus Columbia Inn
Best Western Plus Columbia Inn
2.5 out of 5
2904 Clark Lane, Columbia, MO
The price is $81 per night from May 11 to May 12
$81
includes taxes & fees
May 11 - May 12
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,134 reviews)
"Staff very nice. Comfortable and clean. Great value!"

Reviewed on Apr 22, 2025

Best Western Plus Columbia Inn
Drury Plaza Hotel Columbia East
Drury Plaza Hotel Columbia East
3 out of 5
3100 Interstate 70 Dr. SE, Columbia, MO
The price is $106 per night from May 10 to May 11
$106
includes taxes & fees
May 10 - May 11
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.6/10 Exceptional! (1,110 reviews)
"Dinner happy hour."

Reviewed on Apr 25, 2025

Drury Plaza Hotel Columbia East
See all 210 properties in Mexico
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.