Search Cheap Flights to
Muscatine

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Muscatine Flights as Low as $319

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Tue, Apr 29 - Wed, May 7
PDX
Portland Intl.
MLI
Quad City Intl.
$319 Roundtrip, found 1 day ago
$319
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Apr 29 from Portland Intl. to Quad City Intl., returning Wed, May 7, priced at $319 found 1 day ago
American Airlines
Tue, May 6 - Wed, May 7
PDX
Portland Intl.
MLI
Quad City Intl.
$320 Roundtrip, found 1 day ago
$320
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, May 6 from Portland Intl. to Quad City Intl., returning Wed, May 7, priced at $320 found 1 day ago
Delta
Wed, Jun 18 - Sat, Jun 21
CLT
Charlotte-Douglas Intl.
MLI
Quad City Intl.
$321 Roundtrip, found 21 hours ago
$321
Roundtrip
found 21 hours ago
Select Delta flight, departing Wed, Jun 18 from Charlotte-Douglas Intl. to Quad City Intl., returning Sat, Jun 21, priced at $321 found 21 hours ago
American Airlines
Tue, Feb 25 - Sun, Mar 2
MEM
Memphis Intl.
MLI
Quad City Intl.
$349 Roundtrip, found 1 day ago
$349
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Feb 25 from Memphis Intl. to Quad City Intl., returning Sun, Mar 2, priced at $349 found 1 day ago
American Airlines
Mon, Apr 28 - Wed, May 7
PDX
Portland Intl.
MLI
Quad City Intl.
$349 Roundtrip, found 1 day ago
$349
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Apr 28 from Portland Intl. to Quad City Intl., returning Wed, May 7, priced at $349 found 1 day ago
American Airlines
Mon, May 5 - Sat, May 10
PDX
Portland Intl.
MLI
Quad City Intl.
$350 Roundtrip, found 1 day ago
$350
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, May 5 from Portland Intl. to Quad City Intl., returning Sat, May 10, priced at $350 found 1 day ago
Delta
Tue, Jun 17 - Sat, Jun 21
CLT
Charlotte-Douglas Intl.
MLI
Quad City Intl.
$351 Roundtrip, found 21 hours ago
$351
Roundtrip
found 21 hours ago
Select Delta flight, departing Tue, Jun 17 from Charlotte-Douglas Intl. to Quad City Intl., returning Sat, Jun 21, priced at $351 found 21 hours ago
American Airlines
Wed, Jul 9 - Tue, Jul 15
MYR
Myrtle Beach Intl.
MLI
Quad City Intl.
$354 Roundtrip, found 1 day ago
$354
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Jul 9 from Myrtle Beach Intl. to Quad City Intl., returning Tue, Jul 15, priced at $354 found 1 day ago
American Airlines
Tue, Jul 8 - Tue, Jul 15
MYR
Myrtle Beach Intl.
MLI
Quad City Intl.
$355 Roundtrip, found 1 day ago
$355
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jul 8 from Myrtle Beach Intl. to Quad City Intl., returning Tue, Jul 15, priced at $355 found 1 day ago
Delta
Wed, Apr 30 - Fri, May 9
PDX
Portland Intl.
MLI
Quad City Intl.
$362 Roundtrip, found 1 day ago
$362
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Apr 30 from Portland Intl. to Quad City Intl., returning Fri, May 9, priced at $362 found 1 day ago
Delta
Wed, Jun 18 - Sun, Jun 22
CLT
Charlotte-Douglas Intl.
MLI
Quad City Intl.
$367 Roundtrip, found 21 hours ago
$367
Roundtrip
found 21 hours ago
Select Delta flight, departing Wed, Jun 18 from Charlotte-Douglas Intl. to Quad City Intl., returning Sun, Jun 22, priced at $367 found 21 hours ago
Delta
Mon, Jun 16 - Sat, Jun 21
CLT
Charlotte-Douglas Intl.
MLI
Quad City Intl.
$368 Roundtrip, found 21 hours ago
$368
Roundtrip
found 21 hours ago
Select Delta flight, departing Mon, Jun 16 from Charlotte-Douglas Intl. to Quad City Intl., returning Sat, Jun 21, priced at $368 found 21 hours ago
American Airlines
Tue, Apr 29 - Sun, May 4
PDX
Portland Intl.
MLI
Quad City Intl.
$374 Roundtrip, found 1 day ago
$374
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Apr 29 from Portland Intl. to Quad City Intl., returning Sun, May 4, priced at $374 found 1 day ago
American Airlines
Wed, Apr 30 - Thu, May 8
PDX
Portland Intl.
MLI
Quad City Intl.
$375 Roundtrip, found 1 day ago
$375
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Apr 30 from Portland Intl. to Quad City Intl., returning Thu, May 8, priced at $375 found 1 day ago
Delta
Tue, Apr 29 - Fri, May 2
PDX
Portland Intl.
MLI
Quad City Intl.
$382 Roundtrip, found 1 day ago
$382
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Apr 29 from Portland Intl. to Quad City Intl., returning Fri, May 2, priced at $382 found 1 day ago
American Airlines
Sun, Jun 15 - Sat, Jun 21
CLT
Charlotte-Douglas Intl.
MLI
Quad City Intl.
$419 Roundtrip, found 21 hours ago
$419
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Sun, Jun 15 from Charlotte-Douglas Intl. to Quad City Intl., returning Sat, Jun 21, priced at $419 found 21 hours ago

Cheap Flights to Muscatine

Fall in love at first flight with your vacation to Muscatine by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Muscatine on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Muscatine, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Muscatine

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Muscatine with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MLI airport.

What is the cheapest month to fly to Muscatine?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Muscatine are in April, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Muscatine?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Muscatine.

What airport is best to fly into Muscatine?

When you’re planning your trip to Muscatine, convenience is the name of the game. Luckily, Muscatine Quad City Intl. Airport is nearby so you can deplane and get going on checking off everything on your Muscatine must-do list.

How much are flights to Muscatine?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Muscatine on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $319, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Muscatine?

The trick to saving a stack of cash on your flight to Muscatine? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $319 right now, why wait?

Muscatine Flight Information
Destination airport
Quad City Intl.
Destination airport IATA code
MLI
Roundtrip price
$318

Last Minute Hotel Deals in Muscatine

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
4 out of 5
119 Mississippi Drive West, Muscatine, IA
The price is $160 per night from Mar 14 to Mar 15
$160
includes taxes & fees
Mar 14 - Mar 15
Stay at this 4-star business-friendly hotel in Muscatine. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Riverside Park and Muscatine ...
9.4/10 Exceptional! (245 reviews)
"Really nice room, restaurant, and area around the hotel. 10/10 - will stay there again."

Reviewed on Feb 1, 2025

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
AmericInn by Wyndham Muscatine
AmericInn by Wyndham Muscatine
2.5 out of 5
3115 Hwy 61 North, Muscatine, IA
The price is $90 per night from Mar 2 to Mar 3
$90
includes taxes & fees
Mar 2 - Mar 3
Book a stay at this business-friendly hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and ...
7.4/10 Good! (355 reviews)
Cold
"It was cold in the hallway to and from the pool and anytime you went to breakfast."

Reviewed on Feb 17, 2025

AmericInn by Wyndham Muscatine
Best Western Muscatine / Pearl City Hotel
Best Western Muscatine / Pearl City Hotel
2.5 out of 5
305 Cleveland St, Muscatine, IA
The price is $105 per night from Feb 28 to Mar 1
$105
includes taxes & fees
Feb 28 - Mar 1
Book a stay at this business-friendly hotel in Muscatine. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (432 reviews)
"I stayed at this property while my husband was in the hospital. It is what you would expect for a $89/night stay. The bathroom fixtures were well used and tired looking, although clean. Their complimentary hot breakfast was very good. The overall hotel was clean and all of the front desk staff were ..."

Reviewed on Feb 15, 2025

Best Western Muscatine / Pearl City Hotel
Hampton Inn Muscatine
Hampton Inn Muscatine
2.5 out of 5
3303 N Port Drive, Muscatine, IA
The price is $104 per night from Mar 2 to Mar 3
$104
includes taxes & fees
Mar 2 - Mar 3
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and Muscatine Municipal Golf ...
8.4/10 Very Good! (414 reviews)
"Had a good time"

Reviewed on Dec 21, 2024

Hampton Inn Muscatine
The Sage Hotel
The Sage Hotel
2 out of 5
2402 Park Ave, Muscatine, IA
The price is $69 per night from Feb 24 to Feb 25
$69
includes taxes & fees
Feb 24 - Feb 25
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and Geneva Golf and Country ...
6.6/10 (38 reviews)
"For a very old property, this is a decent value for the price paid. The lobby and breakfast area are clean. The rooms are clean, but not modern. It was quiet and the bed was comfy so it met my needs. I could see that not all rooms, or areas of the property had been addresses by the current owners. ..."

Reviewed on Oct 29, 2024

The Sage Hotel
Wyndham Moline on John Deere Commons
Wyndham Moline on John Deere Commons
3.5 out of 5
1415 River Dr, Moline, IL
The price is $123 per night from Feb 27 to Feb 28
$123
includes taxes & fees
Feb 27 - Feb 28
Book a stay at this eco-certified hotel in Moline. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in ...
8.8/10 Excellent! (1,105 reviews)
"It was super convenient, clean and easy check in. The only down side is they charge for you to park your car. I don’t get this if your at a hotel your most likely from out of town with your car & don’t disclose this. They also put a $50 hold for damages which most are only $25."

Reviewed on Feb 20, 2025

Wyndham Moline on John Deere Commons
Stoney Creek Hotel Quad Cities - Moline
Stoney Creek Hotel Quad Cities - Moline
2.5 out of 5
101 18th St, Moline, IL
The price is $96 per night from Feb 24 to Feb 25
$96
includes taxes & fees
Feb 24 - Feb 25
Book a stay at this business-friendly hotel in Moline. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8/10 Very Good! (1,064 reviews)
Big room, great value
"The room was more than we expected. Very large and roomy. Bed was comfortable and clean. Bathroom was also very clean. Just a few minor things, fridge needed to be defrosted and some of the wallpaper was bubbling. Nothing horrible."

Reviewed on Feb 22, 2025

Stoney Creek Hotel Quad Cities - Moline
Isle Casino Hotel - Bettendorf
Isle Casino Hotel - Bettendorf
3 out of 5
1777 Isle Pkwy, Bettendorf, IA
The price is $114 per night from Feb 24 to Feb 25
$114
includes taxes & fees
Feb 24 - Feb 25
Stay at this 3-star business-friendly hotel in Bettendorf. Enjoy free WiFi, free parking, and a marina. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,006 reviews)
"D"

Reviewed on Feb 21, 2025

Isle Casino Hotel - Bettendorf
See all 300 properties in Muscatine
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.