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Muscatine

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Muscatine Flights as Low as $225

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Cheap Flights to Muscatine

Fall in love at first flight with your vacation to Muscatine by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Muscatine on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Muscatine, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Muscatine

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Muscatine with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MLI airport.

What is the cheapest month to fly to Muscatine?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Muscatine are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Muscatine?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 12 to choose from for your flight to Muscatine.

What airport is best to fly into Muscatine?

When you’re planning your trip to Muscatine, convenience is the name of the game. Luckily, Muscatine Quad City Intl. Airport is nearby so you can deplane and get going on checking off everything on your Muscatine must-do list.

How much are flights to Muscatine?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Muscatine on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $225, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Muscatine?

The trick to saving a stack of cash on your flight to Muscatine? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $225 right now, why wait?

Muscatine Flight Information
Destination airport
Quad City Intl.
Destination airport IATA code
MLI
Roundtrip price
$225

Last Minute Hotel Deals in Muscatine

AmericInn by Wyndham Muscatine

AmericInn by Wyndham Muscatine

2.5 out of 5
3115 Hwy 61 North Muscatine IA
Book a stay at this business-friendly hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and ...
7.6/10 Good! (441 reviews)
They charged me 200 extra even tho no smoking was even done in the room.

Reviewed on Apr 10, 2026

AmericInn by Wyndham Muscatine
Best Western Muscatine / Pearl City Hotel

Best Western Muscatine / Pearl City Hotel

2.5 out of 5
305 Cleveland St Muscatine IA
Book a stay at this business-friendly hotel in Muscatine. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (512 reviews)
Was great came from out of state and had family over swimming and hang out there was no complaints and staff was great and helpful my family and I had a great time will definitely stay again.. !!!!pool was perfect temperature l!!!! Thank you others are very cold can’t swim.

Reviewed on Apr 11, 2026

Best Western Muscatine / Pearl City Hotel
Strawberry Farm Bed & Breakfast

Strawberry Farm Bed & Breakfast

3 out of 5
3402 Tipton Rd Muscatine IA
Stay at this B&B in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Geneva Golf and Country Club and Muscatine Arboretum are ...
9.4/10 Exceptional! (28 reviews)
We had our choices of whatever we wanted for breakfast. It was perfect!

Reviewed on Oct 28, 2025

Strawberry Farm Bed & Breakfast
The Sage Hotel

The Sage Hotel

2 out of 5
2402 Park Ave Muscatine IA
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and Geneva Golf and Country ...
7/10 Good! (66 reviews)
If I wasn’t my friend was in hospice, and I went through a great expense to get there and I didn’t spent much time there,I would have loss the money I paid and gone somewhere else. The place was dirty. Equipment did not work. repairs being done on the building.

Reviewed on Mar 17, 2026

The Sage Hotel
Hampton Inn Muscatine

Hampton Inn Muscatine

2.5 out of 5
3303 N Port Drive Muscatine IA
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and Muscatine Municipal Golf ...
8.4/10 Very Good! (475 reviews)
Need more Equpiment and more weight

Reviewed on Mar 26, 2026

Hampton Inn Muscatine
Comfort Inn Muscatine near Hwy 61

Comfort Inn Muscatine near Hwy 61

2.5 out of 5
115 Cleveland St Muscatine IA
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and Geneva Golf and Country ...
7.8/10 Good! (231 reviews)
Helpful staff. Clean rooms

Reviewed on Apr 8, 2026

Comfort Inn Muscatine near Hwy 61
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

4 out of 5
119 Mississippi Drive West Muscatine IA
Book a stay at this business-friendly hotel in Muscatine. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Riverside Park and Muscatine ...
9.6/10 Exceptional! (287 reviews)
We were there for a wedding and the hotel and service were excellent. As far as the food was concerned, my pork chop was not the best but my wife's chicken was delicious. This is a very nice hotel.

Reviewed on Mar 29, 2026

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
Wyndham Moline on John Deere Commons

Wyndham Moline on John Deere Commons

3.5 out of 5
1415 River Dr Moline IL
Book a stay at this business-friendly hotel in Moline. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,242 reviews)
Quiet

Reviewed on Apr 13, 2026

Wyndham Moline on John Deere Commons
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.