Search Cheap Flights to
Muscatine

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Muscatine Flights as Low as $230

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Sat, May 24 - Tue, May 27
FLL
Fort Lauderdale - Hollywood Intl.
MLI
Quad City Intl.
$230 Roundtrip, found 6 hours ago
$230
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Sat, May 24 from Fort Lauderdale - Hollywood Intl. to Quad City Intl., returning Tue, May 27, priced at $230 found 6 hours ago
United
Sat, May 24 - Tue, May 27
FLL
Fort Lauderdale - Hollywood Intl.
MLI
Quad City Intl.
$233 Roundtrip, found 6 hours ago
$233
Roundtrip
found 6 hours ago
Select United flight, departing Sat, May 24 from Fort Lauderdale - Hollywood Intl. to Quad City Intl., returning Tue, May 27, priced at $233 found 6 hours ago
Delta
Sat, May 24 - Wed, May 28
FLL
Fort Lauderdale - Hollywood Intl.
MLI
Quad City Intl.
$237 Roundtrip, found 6 hours ago
$237
Roundtrip
found 6 hours ago
Select Delta flight, departing Sat, May 24 from Fort Lauderdale - Hollywood Intl. to Quad City Intl., returning Wed, May 28, priced at $237 found 6 hours ago
Delta
Sat, May 24 - Tue, May 27
FLL
Fort Lauderdale - Hollywood Intl.
MLI
Quad City Intl.
$244 Roundtrip, found 6 hours ago
$244
Roundtrip
found 6 hours ago
Select Delta flight, departing Sat, May 24 from Fort Lauderdale - Hollywood Intl. to Quad City Intl., returning Tue, May 27, priced at $244 found 6 hours ago
Delta
Wed, May 21 - Wed, May 28
FLL
Fort Lauderdale - Hollywood Intl.
MLI
Quad City Intl.
$247 Roundtrip, found 6 hours ago
$247
Roundtrip
found 6 hours ago
Select Delta flight, departing Wed, May 21 from Fort Lauderdale - Hollywood Intl. to Quad City Intl., returning Wed, May 28, priced at $247 found 6 hours ago
Delta
Wed, Jun 18 - Sat, Jun 21
ROC
Greater Rochester Intl.
MLI
Quad City Intl.
$250 Roundtrip, found 7 hours ago
$250
Roundtrip
found 7 hours ago
Select Delta flight, departing Wed, Jun 18 from Greater Rochester Intl. to Quad City Intl., returning Sat, Jun 21, priced at $250 found 7 hours ago
Delta
Sat, Sep 13 - Tue, Sep 16
FLL
Fort Lauderdale - Hollywood Intl.
MLI
Quad City Intl.
$251 Roundtrip, found 6 days ago
$251
Roundtrip
found 6 days ago
Select Delta flight, departing Sat, Sep 13 from Fort Lauderdale - Hollywood Intl. to Quad City Intl., returning Tue, Sep 16, priced at $251 found 6 days ago
Delta
Sat, May 24 - Mon, May 26
FLL
Fort Lauderdale - Hollywood Intl.
MLI
Quad City Intl.
$253 Roundtrip, found 6 hours ago
$253
Roundtrip
found 6 hours ago
Select Delta flight, departing Sat, May 24 from Fort Lauderdale - Hollywood Intl. to Quad City Intl., returning Mon, May 26, priced at $253 found 6 hours ago
Delta
Wed, May 21 - Tue, May 27
FLL
Fort Lauderdale - Hollywood Intl.
MLI
Quad City Intl.
$255 Roundtrip, found 6 hours ago
$255
Roundtrip
found 6 hours ago
Select Delta flight, departing Wed, May 21 from Fort Lauderdale - Hollywood Intl. to Quad City Intl., returning Tue, May 27, priced at $255 found 6 hours ago
United
Sat, May 24 - Tue, May 27
FLL
Fort Lauderdale - Hollywood Intl.
MLI
Quad City Intl.
$258 Roundtrip, found 6 hours ago
$258
Roundtrip
found 6 hours ago
Select United flight, departing Sat, May 24 from Fort Lauderdale - Hollywood Intl. to Quad City Intl., returning Tue, May 27, priced at $258 found 6 hours ago
Delta
Fri, Sep 12 - Tue, Sep 16
FLL
Fort Lauderdale - Hollywood Intl.
MLI
Quad City Intl.
$260 Roundtrip, found 6 days ago
$260
Roundtrip
found 6 days ago
Select Delta flight, departing Fri, Sep 12 from Fort Lauderdale - Hollywood Intl. to Quad City Intl., returning Tue, Sep 16, priced at $260 found 6 days ago
Delta
Wed, May 21 - Mon, May 26
FLL
Fort Lauderdale - Hollywood Intl.
MLI
Quad City Intl.
$264 Roundtrip, found 6 hours ago
$264
Roundtrip
found 6 hours ago
Select Delta flight, departing Wed, May 21 from Fort Lauderdale - Hollywood Intl. to Quad City Intl., returning Mon, May 26, priced at $264 found 6 hours ago
American Airlines
Fri, May 23 - Mon, May 26
FLL
Fort Lauderdale - Hollywood Intl.
MLI
Quad City Intl.
$273 Roundtrip, found 6 hours ago
$273
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Fri, May 23 from Fort Lauderdale - Hollywood Intl. to Quad City Intl., returning Mon, May 26, priced at $273 found 6 hours ago
American Airlines
Sat, May 24 - Tue, May 27
FLL
Fort Lauderdale - Hollywood Intl.
MLI
Quad City Intl.
$274 Roundtrip, found 6 hours ago
$274
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Sat, May 24 from Fort Lauderdale - Hollywood Intl. to Quad City Intl., returning Tue, May 27, priced at $274 found 6 hours ago
United
Mon, Apr 21 - Mon, Apr 28
ROC
Greater Rochester Intl.
MLI
Quad City Intl.
$354 Roundtrip, found 1 day ago
$354
Roundtrip
found 1 day ago
Select United flight, departing Mon, Apr 21 from Greater Rochester Intl. to Quad City Intl., returning Mon, Apr 28, priced at $354 found 1 day ago
American Airlines
Fri, Apr 18 - Sat, Apr 19
DFW
Dallas-Fort Worth Intl.
MLI
Quad City Intl.
$609 Roundtrip, found 10 hours ago
$609
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Fri, Apr 18 from Dallas-Fort Worth Intl. to Quad City Intl., returning Sat, Apr 19, priced at $609 found 10 hours ago

Cheap Flights to Muscatine

Fall in love at first flight with your vacation to Muscatine by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Muscatine on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Muscatine, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Muscatine

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Muscatine with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MLI airport.

What is the cheapest month to fly to Muscatine?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Muscatine are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Muscatine?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Muscatine.

What airport is best to fly into Muscatine?

When you’re planning your trip to Muscatine, convenience is the name of the game. Luckily, Muscatine Quad City Intl. Airport is nearby so you can deplane and get going on checking off everything on your Muscatine must-do list.

How much are flights to Muscatine?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Muscatine on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $230, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Muscatine?

The trick to saving a stack of cash on your flight to Muscatine? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $230 right now, why wait?

Muscatine Flight Information
Destination airport
Quad City Intl.
Destination airport IATA code
MLI
Roundtrip price
$229

Last Minute Hotel Deals in Muscatine

Best Western Muscatine / Pearl City Hotel
Best Western Muscatine / Pearl City Hotel
2.5 out of 5
305 Cleveland St, Muscatine, IA
The price is $101 per night from Apr 20 to Apr 21
$101
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Muscatine. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (441 reviews)
"Nice clean place with easy check in"

Reviewed on Feb 23, 2025

Best Western Muscatine / Pearl City Hotel
Hampton Inn Muscatine
Hampton Inn Muscatine
2.5 out of 5
3303 N Port Drive, Muscatine, IA
The price is $104 per night from Apr 24 to Apr 25
$104
includes taxes & fees
Apr 24 - Apr 25
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and Muscatine Municipal Golf ...
8.4/10 Very Good! (418 reviews)
"We were greeted by a very friendly desk agent. We then entered our room to find it squeaking clean. The only drawback was that the breakfast was awful. But we weren’t there for breakfast. Highly recommended."

Reviewed on Apr 14, 2025

Hampton Inn Muscatine
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
4 out of 5
119 Mississippi Drive West, Muscatine, IA
The price is $178 per night from Apr 25 to Apr 26
$178
includes taxes & fees
Apr 25 - Apr 26
Stay at this 4-star business-friendly hotel in Muscatine. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Riverside Park and Muscatine ...
9.4/10 Exceptional! (246 reviews)
"Really nice room, restaurant, and area around the hotel. 10/10 - will stay there again."

Reviewed on Feb 1, 2025

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
AmericInn by Wyndham Muscatine
AmericInn by Wyndham Muscatine
2.5 out of 5
3115 Hwy 61 North, Muscatine, IA
The price is $90 per night from Apr 21 to Apr 22
$90
includes taxes & fees
Apr 21 - Apr 22
Book a stay at this business-friendly hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and ...
7.4/10 Good! (365 reviews)
"Check in/Check out process was very fast and easy. Staff was great!"

Reviewed on Apr 6, 2025

AmericInn by Wyndham Muscatine
Comfort Inn Muscatine near Hwy 61
Comfort Inn Muscatine near Hwy 61
2.5 out of 5
115 Cleveland St, Muscatine, IA
The price is $80 per night from Apr 19 to Apr 20
$80
includes taxes & fees
Apr 19 - Apr 20
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and Geneva Golf and Country ...
7.6/10 Good! (183 reviews)
"Stayed here for 1 night when a friend was in town. Hotel was clean and comfortable. Breakfast in the morning was very good as well. Id stay here again for a great budget hotel with no frills"

Reviewed on Apr 7, 2025

Comfort Inn Muscatine near Hwy 61
The Sage Hotel
The Sage Hotel
2 out of 5
2402 Park Ave, Muscatine, IA
The price is $69 per night from Apr 20 to Apr 21
$69
includes taxes & fees
Apr 20 - Apr 21
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and Geneva Golf and Country ...
6.6/10 (41 reviews)
"Nice a peaceful"

Reviewed on Mar 31, 2025

The Sage Hotel
Stoney Creek Hotel Quad Cities - Moline
Stoney Creek Hotel Quad Cities - Moline
2.5 out of 5
101 18th St, Moline, IL
The price is $113 per night from Apr 17 to Apr 18
$113
includes taxes & fees
Apr 17 - Apr 18
Book a stay at this business-friendly hotel in Moline. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,074 reviews)
"No issues with checking in. Staff courteous. Would stay again."

Reviewed on Apr 9, 2025

Stoney Creek Hotel Quad Cities - Moline
Isle Casino Hotel - Bettendorf
Isle Casino Hotel - Bettendorf
3 out of 5
1777 Isle Pkwy, Bettendorf, IA
The price is $99 per night from Apr 17 to Apr 18
$99
includes taxes & fees
Apr 17 - Apr 18
Stay at this 3-star business-friendly hotel in Bettendorf. Enjoy free WiFi, free parking, and a marina. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,005 reviews)
"Nicr"

Reviewed on Apr 11, 2025

Isle Casino Hotel - Bettendorf
See all 299 properties in Muscatine
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.