Search Cheap Flights to
Muscatine

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Muscatine Flights as Low as $219

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

United
Sat, Oct 11 - Wed, Oct 15
DEN
Denver Intl.
MLI
Quad City Intl.
$219 Roundtrip, found 11 hours ago
$219
Roundtrip
found 11 hours ago
Select United flight, departing Sat, Oct 11 from Denver Intl. to Quad City Intl., returning Wed, Oct 15, priced at $219 found 11 hours ago
American Airlines
Sat, Oct 11 - Wed, Oct 15
DEN
Denver Intl.
MLI
Quad City Intl.
$229 Roundtrip, found 11 hours ago
$229
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Denver Intl. to Quad City Intl., returning Wed, Oct 15, priced at $229 found 11 hours ago
American Airlines
Sat, Oct 11 - Wed, Oct 15
DEN
Denver Intl.
MLI
Quad City Intl.
$239 Roundtrip, found 11 hours ago
$239
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Denver Intl. to Quad City Intl., returning Wed, Oct 15, priced at $239 found 11 hours ago
United
Sat, Oct 11 - Sat, Oct 18
DEN
Denver Intl.
MLI
Quad City Intl.
$239 Roundtrip, found 1 day ago
$239
Roundtrip
found 1 day ago
Select United flight, departing Sat, Oct 11 from Denver Intl. to Quad City Intl., returning Sat, Oct 18, priced at $239 found 1 day ago
Bargain Flight
Sat, Aug 9 - Sat, Aug 16
RSW
Southwest Florida Intl.
MLI
Quad City Intl.
$243 Roundtrip, found 23 hours ago
$243
Roundtrip
found 23 hours ago
Select Bargain Flight flight, departing Sat, Aug 9 from Southwest Florida Intl. to Quad City Intl., returning Sat, Aug 16, priced at $243 found 23 hours ago
United
Sat, Oct 11 - Wed, Oct 15
DEN
Denver Intl.
MLI
Quad City Intl.
$249 Roundtrip, found 11 hours ago
$249
Roundtrip
found 11 hours ago
Select United flight, departing Sat, Oct 11 from Denver Intl. to Quad City Intl., returning Wed, Oct 15, priced at $249 found 11 hours ago
American Airlines
Wed, Sep 17 - Tue, Sep 23
MCO
Orlando Intl.
MLI
Quad City Intl.
$251 Roundtrip, found 1 day ago
$251
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Sep 17 from Orlando Intl. to Quad City Intl., returning Tue, Sep 23, priced at $251 found 1 day ago
Delta
Tue, Sep 16 - Tue, Sep 23
MCO
Orlando Intl.
MLI
Quad City Intl.
$251 Roundtrip, found 3 days ago
$251
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Sep 16 from Orlando Intl. to Quad City Intl., returning Tue, Sep 23, priced at $251 found 3 days ago
American Airlines
Tue, Aug 5 - Tue, Aug 12
CHA
Chattanooga Metropolitan
MLI
Quad City Intl.
$252 Roundtrip, found 1 day ago
$252
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Aug 5 from Chattanooga Metropolitan to Quad City Intl., returning Tue, Aug 12, priced at $252 found 1 day ago
American Airlines
Sat, Aug 9 - Sat, Aug 16
RSW
Southwest Florida Intl.
MLI
Quad City Intl.
$254 Roundtrip, found 23 hours ago
$254
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Sat, Aug 9 from Southwest Florida Intl. to Quad City Intl., returning Sat, Aug 16, priced at $254 found 23 hours ago
United
Tue, Sep 16 - Tue, Sep 23
MCO
Orlando Intl.
MLI
Quad City Intl.
$256 Roundtrip, found 3 days ago
$256
Roundtrip
found 3 days ago
Select United flight, departing Tue, Sep 16 from Orlando Intl. to Quad City Intl., returning Tue, Sep 23, priced at $256 found 3 days ago
United
Sat, Oct 11 - Wed, Oct 15
DEN
Denver Intl.
MLI
Quad City Intl.
$259 Roundtrip, found 11 hours ago
$259
Roundtrip
found 11 hours ago
Select United flight, departing Sat, Oct 11 from Denver Intl. to Quad City Intl., returning Wed, Oct 15, priced at $259 found 11 hours ago
United
Tue, Sep 16 - Tue, Sep 23
MCO
Orlando Intl.
MLI
Quad City Intl.
$260 Roundtrip, found 3 days ago
$260
Roundtrip
found 3 days ago
Select United flight, departing Tue, Sep 16 from Orlando Intl. to Quad City Intl., returning Tue, Sep 23, priced at $260 found 3 days ago
Delta
Fri, Aug 8 - Sun, Aug 17
RSW
Southwest Florida Intl.
MLI
Quad City Intl.
$263 Roundtrip, found 1 day ago
$263
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Aug 8 from Southwest Florida Intl. to Quad City Intl., returning Sun, Aug 17, priced at $263 found 1 day ago
American Airlines
Thu, Sep 11 - Sat, Sep 13
DFW
Dallas-Fort Worth Intl.
MLI
Quad City Intl.
$429 Roundtrip, found 4 days ago
$429
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Sep 11 from Dallas-Fort Worth Intl. to Quad City Intl., returning Sat, Sep 13, priced at $429 found 4 days ago
Delta
Fri, Aug 8 - Mon, Aug 11
DAL
Love Field
MLI
Quad City Intl.
$565 Roundtrip, found 4 days ago
$565
Roundtrip
found 4 days ago
Select Delta flight, departing Fri, Aug 8 from Love Field to Quad City Intl., returning Mon, Aug 11, priced at $565 found 4 days ago

Cheap Flights to Muscatine

Fall in love at first flight with your vacation to Muscatine by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Muscatine on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Muscatine, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Muscatine

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Muscatine with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MLI airport.

What is the cheapest month to fly to Muscatine?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Muscatine are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Muscatine?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to Muscatine.

What airport is best to fly into Muscatine?

When you’re planning your trip to Muscatine, convenience is the name of the game. Luckily, Muscatine Quad City Intl. Airport is nearby so you can deplane and get going on checking off everything on your Muscatine must-do list.

How much are flights to Muscatine?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Muscatine on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $219, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Muscatine?

The trick to saving a stack of cash on your flight to Muscatine? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $219 right now, why wait?

Muscatine Flight Information
Destination airport
Quad City Intl.
Destination airport IATA code
MLI
Roundtrip price
$219

Last Minute Hotel Deals in Muscatine

Best Western Muscatine / Pearl City Hotel
Best Western Muscatine / Pearl City Hotel
2.5 out of 5
305 Cleveland St, Muscatine, IA
Book a stay at this business-friendly hotel in Muscatine. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (455 reviews)
"Staff was prompt and courteous - they paid good attention to the breakfast area and kept things stocked. Hotel was clean and well kept. Pool area was rather small and very full with lots of kids. Overall, good stay!"

Reviewed on May 19, 2025

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Best Western Muscatine / Pearl City Hotel
AmericInn by Wyndham Muscatine
AmericInn by Wyndham Muscatine
2.5 out of 5
3115 Hwy 61 North, Muscatine, IA
Book a stay at this business-friendly hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and ...
7.4/10 Good! (383 reviews)
"Everything was good, the only thing that didn't work was the hot tub. It had no hot water and the timer was to short hopefully thier fixed by the time we go on our next family trip."

Reviewed on Jul 5, 2025

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AmericInn by Wyndham Muscatine
Hampton Inn Muscatine
Hampton Inn Muscatine
2.5 out of 5
3303 N Port Drive, Muscatine, IA
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and Muscatine Municipal Golf ...
8.4/10 Very Good! (428 reviews)
"The staff were very friendly . The breakfast was better than most and the room was comfortable."

Reviewed on Jul 6, 2025

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Hampton Inn Muscatine
Super 8 by Wyndham Muscatine
Super 8 by Wyndham Muscatine
2 out of 5
2900 N Highway 61, Muscatine, IA
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and Geneva Golf and Country ...
6.2/10 (271 reviews)
"Everything was great!"

Reviewed on Sep 30, 2024

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Super 8 by Wyndham Muscatine
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
4 out of 5
119 Mississippi Drive West, Muscatine, IA
Stay at this 4-star business-friendly hotel in Muscatine. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Riverside Park and Muscatine ...
9.4/10 Exceptional! (261 reviews)
"as expected"

Reviewed on Jul 6, 2025

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The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
The Sage Hotel
The Sage Hotel
2 out of 5
2402 Park Ave, Muscatine, IA
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and Geneva Golf and Country ...
6.6/10 (50 reviews)
"Good owners, with a awesome charisma"

Reviewed on Jun 10, 2025

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The Sage Hotel
Comfort Inn Muscatine near Hwy 61
Comfort Inn Muscatine near Hwy 61
2.5 out of 5
115 Cleveland St, Muscatine, IA
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and Geneva Golf and Country ...
7.6/10 Good! (195 reviews)
"Easy to find. Near restaurants. Affordable."

Reviewed on Jul 5, 2025

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Comfort Inn Muscatine near Hwy 61
Strawberry Farm Bed & Breakfast
Strawberry Farm Bed & Breakfast
3 out of 5
3402 Tipton Rd, Muscatine, IA
Stay at this 3-star B&B in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Geneva Golf and Country Club and Discovery Park ...
9.2/10 Wonderful! (26 reviews)
"Nice place, very nice people"

Reviewed on Jun 21, 2025

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Strawberry Farm Bed & Breakfast
See all 292 properties in Muscatine
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.