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São Francisco

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São Francisco Flights as Low as $436

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Air Europa
Tue, Mar 25 - Thu, Mar 27
JFK
John F. Kennedy Intl.
LIS
Humberto Delgado
$436 Roundtrip, found 14 hours ago
$436
Roundtrip
found 14 hours ago
Select Air Europa flight, departing Tue, Mar 25 from John F. Kennedy Intl. to Humberto Delgado, returning Thu, Mar 27, priced at $436 found 14 hours ago
TAP Portugal
Wed, Mar 19 - Thu, Mar 27
EWR
Newark Liberty Intl. Airport
LIS
Humberto Delgado
$528 Roundtrip, found 2 days ago
$528
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Wed, Mar 19 from Newark Liberty Intl. Airport to Humberto Delgado, returning Thu, Mar 27, priced at $528 found 2 days ago
United
Mon, Mar 10 - Fri, Mar 28
SJU
Luis Munoz Marin Intl.
LIS
Humberto Delgado
$541 Roundtrip, found 1 day ago
$541
Roundtrip
found 1 day ago
Select United flight, departing Mon, Mar 10 from Luis Munoz Marin Intl. to Humberto Delgado, returning Fri, Mar 28, priced at $541 found 1 day ago
Air Canada
Tue, Mar 25 - Tue, Apr 8
CLE
Hopkins Intl.
LIS
Humberto Delgado
$565 Roundtrip, found 20 hours ago
$565
Roundtrip
found 20 hours ago
Select Air Canada flight, departing Tue, Mar 25 from Hopkins Intl. to Humberto Delgado, returning Tue, Apr 8, priced at $565 found 20 hours ago
American Airlines
Mon, Mar 10 - Fri, Mar 28
SJU
Luis Munoz Marin Intl.
LIS
Humberto Delgado
$566 Roundtrip, found 1 day ago
$566
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Mar 10 from Luis Munoz Marin Intl. to Humberto Delgado, returning Fri, Mar 28, priced at $566 found 1 day ago
American Airlines
Tue, Nov 11 - Wed, Nov 19
LAX
Los Angeles Intl.
LIS
Humberto Delgado
$571 Roundtrip, found 2 days ago
$571
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Nov 11 from Los Angeles Intl. to Humberto Delgado, returning Wed, Nov 19, priced at $571 found 2 days ago
Air Canada
Wed, Apr 2 - Tue, Apr 8
JFK
John F. Kennedy Intl.
LIS
Humberto Delgado
$572 Roundtrip, found 1 day ago
$572
Roundtrip
found 1 day ago
Select Air Canada flight, departing Wed, Apr 2 from John F. Kennedy Intl. to Humberto Delgado, returning Tue, Apr 8, priced at $572 found 1 day ago
Iberia
Tue, Nov 11 - Wed, Nov 19
LAX
Los Angeles Intl.
LIS
Humberto Delgado
$573 Roundtrip, found 2 days ago
$573
Roundtrip
found 2 days ago
Select Iberia flight, departing Tue, Nov 11 from Los Angeles Intl. to Humberto Delgado, returning Wed, Nov 19, priced at $573 found 2 days ago
Scandinavian Airlines
Wed, Mar 26 - Wed, Apr 2
EWR
Newark Liberty Intl. Airport
LIS
Humberto Delgado
$601 Roundtrip, found 6 days ago
$601
Roundtrip
found 6 days ago
Select Scandinavian Airlines flight, departing Wed, Mar 26 from Newark Liberty Intl. Airport to Humberto Delgado, returning Wed, Apr 2, priced at $601 found 6 days ago
Swiss International Air Lines
Wed, Apr 2 - Tue, Apr 8
JFK
John F. Kennedy Intl.
LIS
Humberto Delgado
$603 Roundtrip, found 1 day ago
$603
Roundtrip
found 1 day ago
Select Swiss International Air Lines flight, departing Wed, Apr 2 from John F. Kennedy Intl. to Humberto Delgado, returning Tue, Apr 8, priced at $603 found 1 day ago
Lufthansa
Tue, Mar 25 - Mon, Mar 31
JFK
John F. Kennedy Intl.
LIS
Humberto Delgado
$613 Roundtrip, found 1 day ago
$613
Roundtrip
found 1 day ago
Select Lufthansa flight, departing Tue, Mar 25 from John F. Kennedy Intl. to Humberto Delgado, returning Mon, Mar 31, priced at $613 found 1 day ago
Virgin Atlantic
Mon, Mar 3 - Tue, Mar 11
BOS
Logan Intl.
LIS
Humberto Delgado
$629 Roundtrip, found 3 days ago
$629
Roundtrip
found 3 days ago
Select Virgin Atlantic flight, departing Mon, Mar 3 from Logan Intl. to Humberto Delgado, returning Tue, Mar 11, priced at $629 found 3 days ago
Delta
Mon, Mar 24 - Tue, Apr 1
AVL
Asheville Regional
LIS
Humberto Delgado
$641 Roundtrip, found 2 days ago
$641
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Mar 24 from Asheville Regional to Humberto Delgado, returning Tue, Apr 1, priced at $641 found 2 days ago
Air Canada
Sat, Mar 22 - Tue, Mar 25
LGA
LaGuardia
LIS
Humberto Delgado
$652 Roundtrip, found 2 days ago
$652
Roundtrip
found 2 days ago
Select Air Canada flight, departing Sat, Mar 22 from LaGuardia to Humberto Delgado, returning Tue, Mar 25, priced at $652 found 2 days ago
Air Canada
Tue, Jun 10 - Fri, Jul 4
GEG
Spokane Intl.
LIS
Humberto Delgado
$1,178 Roundtrip, found 1 day ago
$1,178
Roundtrip
found 1 day ago
Select Air Canada flight, departing Tue, Jun 10 from Spokane Intl. to Humberto Delgado, returning Fri, Jul 4, priced at $1,178 found 1 day ago
Air Canada
Sun, Jun 22 - Wed, Jul 2
CHS
Charleston Intl.
LIS
Humberto Delgado
$1,246 Roundtrip, found 1 day ago
$1,246
Roundtrip
found 1 day ago
Select Air Canada flight, departing Sun, Jun 22 from Charleston Intl. to Humberto Delgado, returning Wed, Jul 2, priced at $1,246 found 1 day ago

Cheap Flights to São Francisco

Fall in love at first flight with your vacation to São Francisco by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to São Francisco on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in São Francisco, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to São Francisco

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to São Francisco with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the LIS airport.

What is the cheapest month to fly to São Francisco?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to São Francisco are in March, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to São Francisco?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to São Francisco.

What airport is best to fly into São Francisco?

When you’re planning your trip to São Francisco, convenience is the name of the game. Luckily, São Francisco Humberto Delgado Airport is nearby so you can deplane and get going on checking off everything on your São Francisco must-do list.

How much are flights to São Francisco?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to São Francisco on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $436, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to São Francisco?

The trick to saving a stack of cash on your flight to São Francisco? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $436 right now, why wait?

São Francisco Flight Information
Destination airport
Humberto Delgado
Destination airport IATA code
LIS
Roundtrip price
$436

Last Minute Hotel Deals in São Francisco

Locke de Santa Joana
Locke de Santa Joana
4 out of 5
18 Rua Camilo Castelo Branco, Lisbon
The price is $96 per night from Feb 23 to Feb 24
$96
includes taxes & fees
Feb 23 - Feb 24
Stay at this 4-star hotel in Lisbon. Enjoy an outdoor pool, 2 restaurants, and 3 bars/lounges. Popular attractions Marquis of Pombal Square and Avenida da Liberdade ...
9.4/10 Exceptional! (489 reviews)
"Nice and very helpful team"

Reviewed on Feb 17, 2025

Locke de Santa Joana
Radisson Blu Hotel
Radisson Blu Hotel
4 out of 5
Avenida Marechal Craveiro Lopes, 390, Campo Grande, Lisbon
The price is $105 per night from Feb 28 to Mar 1
$105
includes taxes & fees
Feb 28 - Mar 1
Stay at this 4-star hotel in Lisbon. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,831 reviews)
"The rooms and beds are comfortable"

Reviewed on Feb 17, 2025

Radisson Blu Hotel
Meliá Lisboa Aeroporto
Meliá Lisboa Aeroporto
4 out of 5
Aeroporto Internacional de Lisboa, Rua C, Lisbon
The price is $176 per night from Mar 2 to Mar 3
$176
includes taxes & fees
Mar 2 - Mar 3
Stay at this 4-star spa hotel in Lisbon. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the pool in our reviews. ...
9.2/10 Wonderful! (2,161 reviews)
"Super convenient place to stay before a trip; the check in and check out were easy. The beds are very comfortable and the rooms are modern and clean. Also enjoyed the Sauna and pool, very nice."

Reviewed on Feb 18, 2025

Meliá Lisboa Aeroporto
easyHotel Lisbon
easyHotel Lisbon
2 out of 5
R. de Santa Marta 60, Lisbon
The price is $67 per night from Feb 27 to Feb 28
$67
includes taxes & fees
Feb 27 - Feb 28
Stay at this hotel in Lisbon. Enjoy breakfast (surcharge), parking (surcharge), and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,240 reviews)
"Came here after a long journey overseas just for sleeping and it did the job. Would have stayed longer! Very clean and the staff were very hospitable"

Reviewed on Feb 17, 2025

easyHotel Lisbon
Hotel Mundial
Hotel Mundial
4 out of 5
Praça Martim Moniz, 2, Lisbon
The price is $150 per night from Feb 23 to Feb 24
$150
includes taxes & fees
Feb 23 - Feb 24
Stay at this 4-star eco-certified hotel in Lisbon. Enjoy free breakfast, free WiFi, and an attached winery. Our guests praise the breakfast and the bar in our ...
8.8/10 Excellent! (1,000 reviews)
"Very nice hotel, nice buffet breakfast every morning. Close to walking anywhere you want to go."

Reviewed on Feb 15, 2025

Hotel Mundial
HF Fénix Lisboa
HF Fénix Lisboa
4 out of 5
Praca Marques de Pombal, 8, Lisbon
The price is $117 per night from Feb 23 to Feb 24
$117
includes taxes & fees
Feb 23 - Feb 24
Stay at this 4-star hotel in Lisbon. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our ...
9/10 Wonderful! (999 reviews)
Great weekend!
"Nice hotel for a weekend stay. Walking distance to the sights, even in February ;) we benefited from so good weather so that helped. Hot breakfast I could take or leave, not the warmest, but a variety of options and lots of fruit. We really liked Lisbon, found everyone to be very friendly and whilst ..."

Reviewed on Feb 15, 2025

HF Fénix Lisboa
Holiday Inn Lisbon, an IHG Hotel
Holiday Inn Lisbon, an IHG Hotel
4 out of 5
Avenida Antonio Jose De Almeida 28-A, Lisbon
The price is $113 per night from Feb 25 to Feb 26
$113
includes taxes & fees
Feb 25 - Feb 26
Stay at this 4-star business-friendly hotel in Lisbon. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the breakfast and the pool ...
8.4/10 Very Good! (1,001 reviews)
"👍"

Reviewed on Feb 9, 2025

Holiday Inn Lisbon, an IHG Hotel
Hotel Borges Chiado
Hotel Borges Chiado
3 out of 5
Rua Garrett, 108-110, Lisbon
The price is $116 per night from Feb 23 to Feb 24
$116
includes taxes & fees
Feb 23 - Feb 24
Stay at this 3-star hotel in Lisbon. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our ...
8.2/10 Very Good! (1,002 reviews)
"Hotel is in an excellent location, room was very spacious and clean. The hotel was excellent value for money and I cannot recommend enough - good job!"

Reviewed on Feb 17, 2025

Hotel Borges Chiado
See all 8,540 properties in São Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.