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Southeast Missouri

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Southeast Missouri Flights as Low as $118

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Sat, Feb 8 - Tue, Feb 11
CLT
Charlotte-Douglas Intl.
STL
Lambert-St. Louis Intl.
$118 Roundtrip, found 6 days ago
$118
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Sat, Feb 8 from Charlotte-Douglas Intl. to Lambert-St. Louis Intl., returning Tue, Feb 11, priced at $118 found 6 days ago
Frontier Airlines
Sat, Feb 8 - Sun, Feb 9
CLT
Charlotte-Douglas Intl.
STL
Lambert-St. Louis Intl.
$128 Roundtrip, found 6 days ago
$128
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Sat, Feb 8 from Charlotte-Douglas Intl. to Lambert-St. Louis Intl., returning Sun, Feb 9, priced at $128 found 6 days ago
Frontier Airlines
Tue, Dec 10 - Wed, Dec 18
CLT
Charlotte-Douglas Intl.
STL
Lambert-St. Louis Intl.
$132 Roundtrip, found 3 days ago
$132
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Tue, Dec 10 from Charlotte-Douglas Intl. to Lambert-St. Louis Intl., returning Wed, Dec 18, priced at $132 found 3 days ago
Frontier Airlines
Fri, Feb 14 - Wed, Feb 19
CLT
Charlotte-Douglas Intl.
STL
Lambert-St. Louis Intl.
$138 Roundtrip, found 6 days ago
$138
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Fri, Feb 14 from Charlotte-Douglas Intl. to Lambert-St. Louis Intl., returning Wed, Feb 19, priced at $138 found 6 days ago
Frontier Airlines
Fri, Feb 14 - Sat, Feb 15
CLT
Charlotte-Douglas Intl.
STL
Lambert-St. Louis Intl.
$142 Roundtrip, found 6 days ago
$142
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Fri, Feb 14 from Charlotte-Douglas Intl. to Lambert-St. Louis Intl., returning Sat, Feb 15, priced at $142 found 6 days ago
Frontier Airlines
Thu, Feb 6 - Sun, Feb 9
CLT
Charlotte-Douglas Intl.
STL
Lambert-St. Louis Intl.
$148 Roundtrip, found 6 days ago
$148
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Thu, Feb 6 from Charlotte-Douglas Intl. to Lambert-St. Louis Intl., returning Sun, Feb 9, priced at $148 found 6 days ago
Frontier Airlines
Wed, Dec 11 - Wed, Dec 18
CLT
Charlotte-Douglas Intl.
STL
Lambert-St. Louis Intl.
$152 Roundtrip, found 3 days ago
$152
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Wed, Dec 11 from Charlotte-Douglas Intl. to Lambert-St. Louis Intl., returning Wed, Dec 18, priced at $152 found 3 days ago
Frontier Airlines
Fri, Nov 22 - Thu, Nov 28
CLT
Charlotte-Douglas Intl.
STL
Lambert-St. Louis Intl.
$158 Roundtrip, found 1 day ago
$158
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Nov 22 from Charlotte-Douglas Intl. to Lambert-St. Louis Intl., returning Thu, Nov 28, priced at $158 found 1 day ago
Spirit Airlines
Tue, Feb 4 - Tue, Feb 11
CLT
Charlotte-Douglas Intl.
STL
Lambert-St. Louis Intl.
$225 Roundtrip, found 6 days ago
$225
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Tue, Feb 4 from Charlotte-Douglas Intl. to Lambert-St. Louis Intl., returning Tue, Feb 11, priced at $225 found 6 days ago
Frontier Airlines
Tue, Nov 19 - Sat, Nov 23
OKC
Will Rogers World
STL
Lambert-St. Louis Intl.
$232 Roundtrip, found 3 days ago
$232
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Tue, Nov 19 from Will Rogers World to Lambert-St. Louis Intl., returning Sat, Nov 23, priced at $232 found 3 days ago
Contour Airlines
Fri, Nov 29 - Mon, Dec 2
CLT
Charlotte-Douglas Intl.
PAH
Barkley Regional
$238 Roundtrip, found 7 hours ago
$238
Roundtrip
found 7 hours ago
Select Contour Airlines flight, departing Fri, Nov 29 from Charlotte-Douglas Intl. to Barkley Regional, returning Mon, Dec 2, priced at $238 found 7 hours ago
Delta
Tue, Dec 10 - Wed, Dec 11
CLT
Charlotte-Douglas Intl.
STL
Lambert-St. Louis Intl.
$336 Roundtrip, found 3 days ago
$336
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Dec 10 from Charlotte-Douglas Intl. to Lambert-St. Louis Intl., returning Wed, Dec 11, priced at $336 found 3 days ago
American Airlines
Fri, Dec 13 - Sat, Dec 14
CLT
Charlotte-Douglas Intl.
STL
Lambert-St. Louis Intl.
$348 Roundtrip, found 3 days ago
$348
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Dec 13 from Charlotte-Douglas Intl. to Lambert-St. Louis Intl., returning Sat, Dec 14, priced at $348 found 3 days ago
United
Fri, Dec 13 - Sat, Dec 14
CLT
Charlotte-Douglas Intl.
STL
Lambert-St. Louis Intl.
$368 Roundtrip, found 3 days ago
$368
Roundtrip
found 3 days ago
Select United flight, departing Fri, Dec 13 from Charlotte-Douglas Intl. to Lambert-St. Louis Intl., returning Sat, Dec 14, priced at $368 found 3 days ago
American Airlines
Thu, Nov 21 - Thu, Nov 28
BNA
Nashville Intl.
PAH
Barkley Regional
$546 Roundtrip, found 2 days ago
$546
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Nov 21 from Nashville Intl. to Barkley Regional, returning Thu, Nov 28, priced at $546 found 2 days ago
American Airlines
Wed, Nov 20 - Sat, Nov 23
OKC
Will Rogers World
PAH
Barkley Regional
$720 Roundtrip, found 15 hours ago
$720
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Wed, Nov 20 from Will Rogers World to Barkley Regional, returning Sat, Nov 23, priced at $720 found 15 hours ago

Cheap Flights to Southeast Missouri

Fall in love at first flight with your vacation to Southeast Missouri by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southeast Missouri on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Southeast Missouri, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Southeast Missouri

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southeast Missouri with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Southeast Missouri?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southeast Missouri are in February, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Southeast Missouri?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Southeast Missouri.

What airport is best to fly into Southeast Missouri?

When you’re planning your trip to Southeast Missouri, convenience is the name of the game. Luckily, Southeast Missouri Cape Girardeau Municipal Airport is nearby so you can deplane and get going on checking off everything on your Southeast Missouri must-do list.

How much are flights to Southeast Missouri?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southeast Missouri on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $118, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Southeast Missouri?

The trick to saving a stack of cash on your flight to Southeast Missouri? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $118 right now, why wait?

Southeast Missouri Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$221

Last Minute Hotel Deals in Southeast Missouri

Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MO
2 out of 5
4101 Highway 67 N, Poplar Bluff, MO
The price is $79 per night from Nov 18 to Nov 19
$79
includes taxes & fees
Nov 18 - Nov 19
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,005 reviews)
"I like thr quite. Dislike the security."

Reviewed on Nov 14, 2024

Motel 6 Poplar Bluff, MO
Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MO
2.5 out of 5
1625 W Columbia St, Farmington, MO
The price is $59 per night from Nov 23 to Nov 24
$59
includes taxes & fees
Nov 23 - Nov 24
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (791 reviews)
Great stay
"Wonderful stay, great price... I was pleasantly surprised... will be back!"

Reviewed on Nov 12, 2024

Baymont Inn and Suites by Wyndham Farmington, MO
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
The price is $81 per night from Nov 24 to Nov 25
$81
includes taxes & fees
Nov 24 - Nov 25
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,001 reviews)
"Stayed here with my wife and daughter while in town to attend a concert happening after the rodeo. Everything with this property was great. The room was clean, the beds & bedding were clean and comfortable, the highway is easy to access, and the staff was great. No complaints and would stay here ..."

Reviewed on Nov 14, 2024

Pear Tree Inn Cape Girardeau West
The Riverview
The Riverview
3.5 out of 5
777 Main St, Cape Girardeau, MO
The price is $121 per night from Nov 18 to Nov 19
$121
includes taxes & fees
Nov 18 - Nov 19
Stay at this 3.5-star hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and Riverfront ...
9/10 Wonderful! (81 reviews)
"The hotel was beautiful and clean. Very convenient with dining options and casino all located inside with the hotel. The restaurant, Beacon 53, was absolutely amazing and the staff was friendly and helpful."

Reviewed on Nov 10, 2024

The Riverview
Auburn Place Hotel And Suites
Auburn Place Hotel And Suites
2.5 out of 5
3265 William St, Cape Girardeau, MO
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
8.8/10 Excellent! (1,004 reviews)
Great for families
"I love going here when we visit! The pool is great during down time and the kids love playing the games. They have a good breakfast and are usually pretty friendly"

Reviewed on Nov 14, 2024

Get rates
Auburn Place Hotel And Suites
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
3 out of 5
3303 Campster Drive, Cape Girardeau, MO
The price is $107 per night from Nov 21 to Nov 22
$107
includes taxes & fees
Nov 21 - Nov 22
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (813 reviews)
"Awesome customer service and excellent facilities. Room was top notch for price!!"

Reviewed on Nov 16, 2024

Drury Inn & Suites Cape Girardeau
Candlewood Suites Cape Girardeau, an IHG Hotel
Candlewood Suites Cape Girardeau, an IHG Hotel
2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
The price is $103 per night from Dec 15 to Dec 16
$103
includes taxes & fees
Dec 15 - Dec 16
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (695 reviews)
Amazing value for amazing stay!
"This was my first time at candlewood suites, we went for a fun weekend at Cape Con and we were so impressed with our room! It was an amazing value and the rooms were extremely clean and well stocked. The pool was also a plus!! We will absolutely be returning, Candlewood made us want to make this ..."

Reviewed on Nov 4, 2024

Candlewood Suites Cape Girardeau, an IHG Hotel
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
2.5 out of 5
3253 William Street, Cape Girardeau, MO
The price is $107 per night from Dec 1 to Dec 2
$107
includes taxes & fees
Dec 1 - Dec 2
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (999 reviews)
"Our only complaint was the kids channels weren’t working on the TV. Other than that clean, quiet, polite, good eating area"

Reviewed on Nov 10, 2024

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
See all 536 properties in Southeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.