Search Cheap Flights toSoutheast Missouri
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Southeast Missouri Flights as Low as $153
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
Tue, Mar 11 - Tue, Mar 18
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$153 Roundtrip, found 1 day ago
$153
Roundtrip
found 1 day ago
Mon, Mar 10 - Tue, Mar 18
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$163 Roundtrip, found 1 day ago
$163
Roundtrip
found 1 day ago
Fri, Mar 14 - Tue, Mar 18
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$194 Roundtrip, found 1 day ago
$194
Roundtrip
found 1 day ago
Sat, Mar 15 - Tue, Mar 18
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$202 Roundtrip, found 1 day ago
$202
Roundtrip
found 1 day ago
Thu, Mar 13 - Tue, Mar 18
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$209 Roundtrip, found 1 day ago
$209
Roundtrip
found 1 day ago
Tue, Mar 4 - Tue, Mar 11
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$217 Roundtrip, found 1 day ago
$217
Roundtrip
found 1 day ago
Fri, May 2 - Sat, May 3
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$217 Roundtrip, found 3 days ago
$217
Roundtrip
found 3 days ago
Tue, Mar 11 - Mon, Mar 17
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$218 Roundtrip, found 13 hours ago
$218
Roundtrip
found 13 hours ago
Tue, Mar 11 - Mon, Mar 17
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$224 Roundtrip, found 13 hours ago
$224
Roundtrip
found 13 hours ago
Tue, Mar 11 - Thu, Mar 13
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$225 Roundtrip, found 1 day ago
$225
Roundtrip
found 1 day ago
Fri, May 2 - Sat, May 3
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$227 Roundtrip, found 3 days ago
$227
Roundtrip
found 3 days ago
Tue, Mar 11 - Mon, Mar 17
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$228 Roundtrip, found 13 hours ago
$228
Roundtrip
found 13 hours ago
Tue, Mar 11 - Mon, Mar 17
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$230 Roundtrip, found 13 hours ago
$230
Roundtrip
found 13 hours ago
Tue, Mar 18 - Tue, Mar 25
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$247 Roundtrip, found 3 days ago
$247
Roundtrip
found 3 days ago
Tue, May 20 - Tue, May 27
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$260 Roundtrip, found 5 days ago
$260
Roundtrip
found 5 days ago
Tue, May 20 - Fri, May 23
DAL
Love Field
STL
Lambert-St. Louis Intl.
$285 Roundtrip, found 5 days ago
$285
Roundtrip
found 5 days ago
Cheap Flights to Southeast Missouri
Fall in love at first flight with your vacation to Southeast Missouri by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southeast Missouri on Hotwire, and you’ll be up, up, and on a getaway in no time.
Because once the wheels are down in Southeast Missouri, the good times start rolling. So buckle up, you’re in for a fun ride.
Frequently Asked Questions About flights to Southeast Missouri
Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southeast Missouri with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.
So all you have to worry about is where you’re headed after the STL airport.
What is the cheapest month to fly to Southeast Missouri?
Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southeast Missouri are in March, but when you book your flight on Hotwire, savings are always in season.
How many airlines fly to Southeast Missouri?
Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Southeast Missouri.
What airport is best to fly into Southeast Missouri?
When you’re planning your trip to Southeast Missouri, convenience is the name of the game. Luckily, Southeast Missouri Cape Girardeau Municipal Airport is nearby so you can deplane and get going on checking off everything on your Southeast Missouri must-do list.
How much are flights to Southeast Missouri?
Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southeast Missouri on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $153, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.
How to get cheap flights to Southeast Missouri?
The trick to saving a stack of cash on your flight to Southeast Missouri? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $153 right now, why wait?
Destination airport | Lambert-St. Louis Intl. |
Destination airport IATA code | STL |
Roundtrip price | $140 |
Last Minute Hotel Deals in Southeast Missouri
The Riverview
777 Main St, Cape Girardeau, MO
The price is $109 per night from Feb 23 to Feb 24
$109
includes taxes & fees
Feb 23 - Feb 24
Stay at this 3.5-star hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and Riverfront ...
9.2/10 Wonderful! (152 reviews)
"Very nice and so easy to get into the casino."
Reviewed on Feb 17, 2025
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
The price is $112 per night from Feb 24 to Feb 25
$112
includes taxes & fees
Feb 24 - Feb 25
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,002 reviews)
"Easy check in. Front desk was incredibly kind and friendly. The room was large and very clean. Guests are provided free dinner and breakfast, and there’s so much to choose from and it’s all delicious. I’d pick this place every time."
Reviewed on Feb 19, 2025
Motel 6 Poplar Bluff, MO
4101 Highway 67 N, Poplar Bluff, MO
The price is $76 per night from Feb 23 to Feb 24
$76
includes taxes & fees
Feb 23 - Feb 24
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,003 reviews)
"Staff was great, there was no coffee in room or lobby. Had to go to front desk for tp."
Reviewed on Feb 19, 2025
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
3253 William Street, Cape Girardeau, MO
The price is $112 per night from Mar 1 to Mar 2
$112
includes taxes & fees
Mar 1 - Mar 2
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (999 reviews)
"Always a great stay!"
Reviewed on Feb 17, 2025
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St, Farmington, MO
The price is $64 per night from Feb 28 to Mar 1
$64
includes taxes & fees
Feb 28 - Mar 1
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (858 reviews)
"Exceeded my expectations for the price. Good breakfast"
Reviewed on Feb 18, 2025
Drury Inn & Suites Cape Girardeau
3303 Campster Drive, Cape Girardeau, MO
The price is $107 per night from Feb 24 to Feb 25
$107
includes taxes & fees
Feb 24 - Feb 25
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (892 reviews)
"Very nicely updated Comfortable beds Friendly and helpful staff"
Reviewed on Feb 17, 2025
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
The price is $88 per night from Feb 23 to Feb 24
$88
includes taxes & fees
Feb 23 - Feb 24
Book a stay at this business-friendly hotel in Jackson. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (507 reviews)
"Friendly staff and clean. No noise room comfortable."
Reviewed on Jan 27, 2025
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy, Cape Girardeau, MO
The price is $71 per night from Mar 2 to Mar 3
$71
includes taxes & fees
Mar 2 - Mar 3
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,005 reviews)
"Nice quiet, safe hotel"
Reviewed on Feb 14, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeast Missouri Hotels
- Motel 6 Poplar Bluff, MO
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
- Baymont Inn and Suites by Wyndham Farmington, MO
- La Quinta Inn & Suites by Wyndham Festus - St. Louis South
- Quality Inn
- Candlewood Suites Cape Girardeau, an IHG Hotel
- Days Inn and Suites by Wyndham Sikeston
- Fairfield Inn & Suites by Marriott Poplar Bluff