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St. James

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St. James Flights as Low as $380

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$380 Roundtrip, found 2 hours ago
$380
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $380 found 2 hours ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$386 Roundtrip, found 2 hours ago
$386
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $386 found 2 hours ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$413 Roundtrip, found 2 hours ago
$413
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $413 found 2 hours ago
American Airlines
Sat, Oct 11 - Fri, Oct 17
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$413 Roundtrip, found 14 hours ago
$413
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Fri, Oct 17, priced at $413 found 14 hours ago
American Airlines
Sat, Oct 11 - Fri, Oct 17
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$419 Roundtrip, found 14 hours ago
$419
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Fri, Oct 17, priced at $419 found 14 hours ago
American Airlines
Fri, Oct 10 - Sat, Oct 11
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$424 Roundtrip, found 5 days ago
$424
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Oct 10 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Sat, Oct 11, priced at $424 found 5 days ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$426 Roundtrip, found 2 hours ago
$426
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $426 found 2 hours ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$432 Roundtrip, found 2 hours ago
$432
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $432 found 2 hours ago
American Airlines
Fri, Oct 10 - Sat, Oct 11
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$437 Roundtrip, found 5 days ago
$437
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Oct 10 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Sat, Oct 11, priced at $437 found 5 days ago
American Airlines
Fri, Oct 10 - Sat, Oct 11
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$442 Roundtrip, found 5 days ago
$442
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Oct 10 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Sat, Oct 11, priced at $442 found 5 days ago
American Airlines
Sat, Oct 11 - Fri, Oct 17
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$446 Roundtrip, found 14 hours ago
$446
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Fri, Oct 17, priced at $446 found 14 hours ago
American Airlines
Fri, Oct 10 - Fri, Oct 17
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$446 Roundtrip, found 1 day ago
$446
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Oct 10 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Fri, Oct 17, priced at $446 found 1 day ago
American Airlines
Fri, Oct 10 - Sat, Oct 11
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$448 Roundtrip, found 5 days ago
$448
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Oct 10 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Sat, Oct 11, priced at $448 found 5 days ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$450 Roundtrip, found 2 hours ago
$450
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $450 found 2 hours ago
United
Mon, Oct 6 - Sat, Oct 18
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$462 Roundtrip, found 2 days ago
$462
Roundtrip
found 2 days ago
Select United flight, departing Mon, Oct 6 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Sat, Oct 18, priced at $462 found 2 days ago
American Airlines
Fri, Aug 8 - Mon, Aug 11
MSY
Louis Armstrong New Orleans Intl.
TBN
St. Robert Regional
$504 Roundtrip, found 2 days ago
$504
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Aug 8 from Louis Armstrong New Orleans Intl. to St. Robert Regional, returning Mon, Aug 11, priced at $504 found 2 days ago

Cheap Flights to St. James

Fall in love at first flight with your vacation to St. James by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to St. James on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in St. James, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to St. James

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to St. James with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the COU airport.

What is the cheapest month to fly to St. James?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to St. James are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to St. James?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to St. James.

What airport is best to fly into St. James?

When you’re planning your trip to St. James, convenience is the name of the game. Luckily, St. James St. Robert Regional Airport is nearby so you can deplane and get going on checking off everything on your St. James must-do list.

How much are flights to St. James?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to St. James on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $380, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to St. James?

The trick to saving a stack of cash on your flight to St. James? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $380 right now, why wait?

St. James Flight Information
Destination airport
Columbia Regional
Destination airport IATA code
COU
Roundtrip price
$380

Last Minute Hotel Deals in St. James

Greenlight Inn & Suites

Greenlight Inn & Suites

2 out of 5
110 N Outer Rd, St. James, MO
Book a stay at this business-friendly hotel in St. James. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (308 reviews)
"Great budget friendly option! We just needed a bed to sleep in for the night and decent breakfast options during a cross country road trip."

Reviewed on Jul 28, 2025

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Greenlight Inn & Suites
Economy Inn

Economy Inn

2.5 out of 5
102 N Outer Rd, St. James, MO
Stay at this motel in St. James. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (448 reviews)
"Clean, quiet, and incredible staff!"

Reviewed on Jul 27, 2025

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Economy Inn
Finns Motel

Finns Motel

2.5 out of 5
777 Grover St, St. James, MO
Stay at this motel in St. James. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.8/10 Good! (314 reviews)
"It was clean and quiet, no poblems!"

Reviewed on Jul 27, 2025

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Finns Motel
Baymont by Wyndham Rolla

Baymont by Wyndham Rolla

2.5 out of 5
1801 Martin Springs Dr, I-44 Exit 184, Rolla, MO
Book a stay at this business-friendly hotel in Rolla. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,002 reviews)
"Appreciated the clean and comfy room. The staff at check in wasn’t super friendly, but overall still a good stay."

Reviewed on Jul 29, 2025

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Baymont by Wyndham Rolla
Days Inn by Wyndham Rolla

Days Inn by Wyndham Rolla

2.5 out of 5
2006 N Bishop Ave, Rolla, MO
Book a stay at this business-friendly hotel in Rolla. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,009 reviews)
Quiet, comfortable, Clean
"On my way moving from one state to another and this hotel was my mid way stay. Nice and quiet."

Reviewed on Jul 16, 2025

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Days Inn by Wyndham Rolla
Comfort Suites Rolla

Comfort Suites Rolla

2.5 out of 5
1650 Old Wire Outer Rd, Rolla, MO
Book a stay at this business-friendly hotel in Rolla. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (868 reviews)
Comfortable Stay
"Overall, a good stay. The TV in our room was not connecting, and after we attempted to troubleshoot the issue, the manager on duty relocated us to a new room, which we appreciated. The beds were comfortable and the room was clean."

Reviewed on Jul 23, 2025

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Comfort Suites Rolla
Econo Lodge Rolla I-44 Exit 184 Near Missouri University of Science and Technology

Econo Lodge Rolla I-44 Exit 184 Near Missouri University of Science and Technology

2 out of 5
1417 Martin Springs Dr, Rolla, MO
Stay at this hotel in Rolla. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Allgood-Bailey Stadium and Stonehenge Replica are located ...
6.8/10 (524 reviews)
"Staff was very kind & efficient. Rooms were old but clean. No bed bugs, used mattress covers & watched housekeeping pull off & wash comfortrrs"

Reviewed on Jul 19, 2025

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Econo Lodge Rolla I-44 Exit 184 Near Missouri University of Science and Technology
Days Inn & Suites by Wyndham Cuba

Days Inn & Suites by Wyndham Cuba

2 out of 5
97 Ozark Drive, Cuba, MO
Book a stay at this business-friendly hotel in Cuba. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
7.2/10 Good! (724 reviews)
"The manager was helpful in recommending restaurants. The pool was very warm. Breakfast was good."

Reviewed on Jul 29, 2025

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Days Inn & Suites by Wyndham Cuba
See all 186 properties in St. James
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.