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St. James

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St. James Flights as Low as $380

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$380 Roundtrip, found 2 hours ago
$380
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $380 found 2 hours ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$386 Roundtrip, found 2 hours ago
$386
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $386 found 2 hours ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$426 Roundtrip, found 2 hours ago
$426
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $426 found 2 hours ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$432 Roundtrip, found 2 hours ago
$432
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $432 found 2 hours ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$450 Roundtrip, found 2 hours ago
$450
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $450 found 2 hours ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$456 Roundtrip, found 2 hours ago
$456
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $456 found 2 hours ago
United
Tue, Oct 14 - Fri, Oct 17
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$456 Roundtrip, found 22 hours ago
$456
Roundtrip
found 22 hours ago
Select United flight, departing Tue, Oct 14 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Fri, Oct 17, priced at $456 found 22 hours ago
United
Sat, Oct 11 - Fri, Oct 17
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$457 Roundtrip, found 22 hours ago
$457
Roundtrip
found 22 hours ago
Select United flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Fri, Oct 17, priced at $457 found 22 hours ago
American Airlines
Fri, Oct 10 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$457 Roundtrip, found 8 hours ago
$457
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Fri, Oct 10 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $457 found 8 hours ago
United
Sat, Oct 11 - Mon, Oct 13
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$468 Roundtrip, found 22 hours ago
$468
Roundtrip
found 22 hours ago
Select United flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Mon, Oct 13, priced at $468 found 22 hours ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$472 Roundtrip, found 2 hours ago
$472
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $472 found 2 hours ago
United
Fri, Oct 10 - Fri, Oct 17
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$476 Roundtrip, found 22 hours ago
$476
Roundtrip
found 22 hours ago
Select United flight, departing Fri, Oct 10 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Fri, Oct 17, priced at $476 found 22 hours ago
United
Fri, Oct 10 - Mon, Oct 13
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$487 Roundtrip, found 22 hours ago
$487
Roundtrip
found 22 hours ago
Select United flight, departing Fri, Oct 10 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Mon, Oct 13, priced at $487 found 22 hours ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$496 Roundtrip, found 2 hours ago
$496
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $496 found 2 hours ago
American Airlines
Fri, Jun 20 - Thu, Jun 26
PDX
Portland Intl.
COU
Columbia Regional
$576 Roundtrip, found 1 day ago
$576
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Jun 20 from Portland Intl. to Columbia Regional, returning Thu, Jun 26, priced at $576 found 1 day ago
American Airlines
Mon, Jun 2 - Sat, Jun 7
BOS
Logan Intl.
COU
Columbia Regional
$638 Roundtrip, found 4 days ago
$638
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, Jun 2 from Logan Intl. to Columbia Regional, returning Sat, Jun 7, priced at $638 found 4 days ago

Cheap Flights to St. James

Fall in love at first flight with your vacation to St. James by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to St. James on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in St. James, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to St. James

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to St. James with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the COU airport.

What is the cheapest month to fly to St. James?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to St. James are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to St. James?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to St. James.

What airport is best to fly into St. James?

When you’re planning your trip to St. James, convenience is the name of the game. Luckily, St. James St. Robert Regional Airport is nearby so you can deplane and get going on checking off everything on your St. James must-do list.

How much are flights to St. James?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to St. James on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $380, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to St. James?

The trick to saving a stack of cash on your flight to St. James? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $380 right now, why wait?

St. James Flight Information
Destination airport
Columbia Regional
Destination airport IATA code
COU
Roundtrip price
$380

Last Minute Hotel Deals in St. James

Greenlight Inn & Suites
Greenlight Inn & Suites
2 out of 5
110 N Outer Rd, St. James, MO
Book a stay at this business-friendly hotel in St. James. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (238 reviews)
"Nice place to stay on our way through the area."

Reviewed on May 27, 2025

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Greenlight Inn & Suites
Economy Inn
Economy Inn
2.5 out of 5
102 N Outer Rd, St. James, MO
Stay at this motel in St. James. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (427 reviews)
"Amazing staff, very accomodating and generous! Clean rooms and comfy beds!"

Reviewed on May 28, 2025

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Economy Inn
Finns Motel
Finns Motel
2.5 out of 5
777 Grover St, St. James, MO
Stay at this motel in St. James. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.8/10 Good! (298 reviews)
"Ended up needing a place to stay last minute on a long haul home. Found this place online and from the reviews and pricing we gave it a shot. My friend and i had a great experience and the staff was so polite! Definitely recommend if you’re passing through Missouri and need a place to stay in a pinch, ..."

Reviewed on May 22, 2025

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Finns Motel
Days Inn by Wyndham Rolla
Days Inn by Wyndham Rolla
2.5 out of 5
2006 N Bishop Ave, Rolla, MO
Book a stay at this business-friendly hotel in Rolla. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,000 reviews)
"Convenient location just off the highway. Only scramble eggs for breakfast. No other options or pastries."

Reviewed on May 2, 2025

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Days Inn by Wyndham Rolla
Baymont by Wyndham Rolla
Baymont by Wyndham Rolla
2.5 out of 5
1801 Martin Springs Dr, I-44 Exit 184, Rolla, MO
Book a stay at this business-friendly hotel in Rolla. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,003 reviews)
"Fast & friendly service at check in. Room looked great."

Reviewed on May 26, 2025

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Baymont by Wyndham Rolla
Fairfield Inn & Suites by Marriott Rolla
Fairfield Inn & Suites by Marriott Rolla
2.5 out of 5
1670 Old Wire Outer Road, Rolla, MO
Stay at this hotel in Rolla. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.6/10 Exceptional! (428 reviews)
"Everything was super clean and beds were comfy. Breakfast was above average for continental breakfast. Big variety of things to choose from and staff were very helpful and friendly."

Reviewed on May 27, 2025

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Fairfield Inn & Suites by Marriott Rolla
Days Inn & Suites by Wyndham Cuba
Days Inn & Suites by Wyndham Cuba
2 out of 5
97 Ozark Drive, Cuba, MO
Book a stay at this business-friendly hotel in Cuba. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
7.2/10 Good! (686 reviews)
"Clean comfortable bed"

Reviewed on May 17, 2025

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Days Inn & Suites by Wyndham Cuba
Econo Lodge Rolla I-44 Exit 184 Near Missouri University of Science and Technology
Econo Lodge Rolla I-44 Exit 184 Near Missouri University of Science and Technology
2 out of 5
1417 Martin Springs Dr, Rolla, MO
Stay at this hotel in Rolla. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Allgood-Bailey Stadium and Lions Club Park are located ...
6.8/10 (498 reviews)
"Very close to Missouri S&T where our Grandson is graduating. Nice clean room and reasonably priced is what we like and appreciate."

Reviewed on May 17, 2025

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Econo Lodge Rolla I-44 Exit 184 Near Missouri University of Science and Technology
See all 181 properties in St. James
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.