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Featured Greenville Family Hotels

Super 8 by Wyndham Greenville
1700 State Route 127, Greenville, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly motel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

Comfort Inn & Suites Greenville I-70
2265 S. State Route 127, Greenville, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

SureStay Hotel by Best Western Greenville
1731 S State Route 127, Greenville, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels with Pools in Greenville

SureStay Hotel by Best Western Greenville
1731 S State Route 127, Greenville, IL
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the helpful staff ...
7.4/10 Good! (506 reviews)
Overnight retreat
"Second time i was staying over in Greenville and had a room one door down from previous stay. Big and clean. Smelled good, quiet and again one of the most comfy beds I've ever slept in. Front desk was helpful, and polite."
Reviewed on Mar 18, 2025

Comfort Inn & Suites Greenville I-70
2265 S. State Route 127, Greenville, IL
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (360 reviews)
"Staff was great. There was glass in the pool. My child cut their toe and another cut their foot. Very disappointing. Rooms are basic and need updating."
Reviewed on Mar 2, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels With Connecting Rooms in Greenville

Super 8 by Wyndham Greenville
1700 State Route 127, Greenville, IL
Book a stay at this business-friendly motel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
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Top Points of Interests in Greenville
- Hotels near Greenville Country Club
- Hotels near Patriot's Park
- Hotels near Carlyle Lake
- Hotels near Lake Lou Yeager
- Hotels near Copper Dock Winery
- Hotels near Hazlet State Park
- Hotels near Governors Run Golf Course
- Hotels near McGath's Lake Trail
- Hotels near Crooked Creek Winery
- Hotels near Spillway Recreation Area
- Hotels near Korte Recreation Center
- Hotels near Vandalia State House
- Hotels near West Access Marina
- Hotels near Litchfield Museum and Route 66 Welcome Center
- Hotels near The Winery at Shale Lake
- Hotels near Henry's Rabbit Ranch
- Hotels near Silver Lake Park
- Hotels near Clinton County Fairgrounds
- Hotels near Timber Lakes Golf Course
Cities near Greenville
- Edwardsville Hotels (31.22 mi)
- Southern Illinois Hotels (45.85 mi)
- Litchfield Hotels (23.59 mi)
- Troy Hotels (29.31 mi)
- Centralia Hotels (29.41 mi)
- Vandalia Hotels (17.8 mi)
- Highland Hotels (17.44 mi)
- Central United States Hotels (233.4 mi)
- Central Illinois Hotels (92.1 mi)
- Lebanon Hotels (29.1 mi)
- Carlyle Hotels (19.56 mi)
- Historic Route 66 Hotels (505.22 mi)
- Staunton Hotels (21.93 mi)
- Hillsboro Hotels (19.06 mi)
- Pocahontas Hotels (8.15 mi)
- Breese Hotels (20.01 mi)
- Sorento Hotels (11.38 mi)
- Mulberry Grove Hotels (8.07 mi)
- Hamel Hotels (22.91 mi)
- Brownstown Hotels (25.73 mi)
Car Rentals Near Greenville
- Car rentals in Edwardsville
- Car rentals in Southern Illinois
- Car rentals in Litchfield
- Car rentals in Troy
- Car rentals in Centralia
- Car rentals in Vandalia
- Car rentals in Highland
- Car rentals in Central United States
- Car rentals in Central Illinois
- Car rentals in Lebanon
- Car rentals in Carlyle
- Car rentals in Historic Route 66
- Car rentals in Staunton
- Car rentals in Hillsboro
- Car rentals in Pocahontas
- Car rentals in Breese
Top Family Hotel Destinations
- Las Vegas Family Hotels
- Arcade Family Hotels
- Branson Family Hotels
- Biloxi Family Hotels
- Ocean City Family Hotels
- Orlando Family Hotels
- Buffalo Family Hotels
- Reno Family Hotels
- Colorado Springs Family Hotels
- Phoenix Family Hotels
- Niagara Falls Family Hotels
- New York Family Hotels
- Whistler Family Hotels
- Houston Family Hotels
- Fort Walton Beach Family Hotels
- Pensacola Beach Family Hotels
- Tampa Family Hotels
- Myrtle Beach Family Hotels
- Miami Beach Family Hotels
- Birmingham Family Hotels
Top Booked Hotels in Greenville
- Super 8 by Wyndham Greenville
- SureStay Hotel by Best Western Greenville
- Holiday Inn Express & Suites Vandalia by IHG
- Quality Inn & Suites Vandalia near I-70 and Hwy 51
- Holiday Inn Express & Suites Litchfield West by IHG
- Seasons Inn & Suites Highland
- Best Western Plus Centralia Hotel & Suites
- Baymont by Wyndham Litchfield
- Hampton Inn by Hilton Litchfield
- Ramada by Wyndham Vandalia
- Quality Inn Litchfield Route 66
- Super 8 by Wyndham Staunton
- Americas Best Value Inn Vandalia